Patents Assigned to Byk Gulden Lomberg Chemische Fabrik GmbH
  • Patent number: 6884437
    Abstract: Novel administration forms for acid-labile active compounds are described. The novel administration forms have no enteric layers and are suitable for oral administration.
    Type: Grant
    Filed: April 25, 2003
    Date of Patent: April 26, 2005
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Rudolf Linder, Rango Dietrich
  • Publication number: 20030050329
    Abstract: The invention relates to the combined use of the PDE4 inhibitor N-(3,5-dichloropyrid-4-yl)-3-cyclopropylmethoxy-4-difluoromethoxybenzamide, its pharmacologically tolerable salts or its N-oxide with a PDE3 inhibitor for the treatment of certain disease conditions such as, for example, acute or chronic obstructions of the bronchi.
    Type: Application
    Filed: November 4, 2002
    Publication date: March 13, 2003
    Applicant: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Ulrich Kilian
  • Publication number: 20030007931
    Abstract: A composition comprising a combination of a compound of formula I 1
    Type: Application
    Filed: June 4, 2002
    Publication date: January 9, 2003
    Applicant: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Dietrich Hafner
  • Publication number: 20020188008
    Abstract: The invention relates to the dihydrate of the magnesium salt of pantoprazole.
    Type: Application
    Filed: May 1, 2002
    Publication date: December 12, 2002
    Applicant: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Bernhard Kohl
  • Patent number: 6489327
    Abstract: The invention relates to novel inhibitors of human tryptase which are used in the pharmaceutical industry for the production of medicaments.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: December 3, 2002
    Assignees: Max-Planck-Gesellschaft zur Fordrungder Wisenschaften, e.V., Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Thomas Bär, Thomas Martin, Josef Stadlwieser, Wolf-Rüdiger Ulrich, Andreas Dominik, Ulrich Thibaut, Daniela Bundschuh, Rolf Beume, Karl-Josef Goebel, Wolfram Bode, Luis Moroder, Pedro Jose Barbosa Pereira, Andreas Bergner, Robert Huber, Christian Sommerhoff, Norbert Schaschke
  • Publication number: 20020169320
    Abstract: Compounds of formula (1) in which the substituents have the meanings mentioned in the description, are suitable for the prevention and treatment of gastrointestinal diseases.
    Type: Application
    Filed: March 25, 2002
    Publication date: November 14, 2002
    Applicant: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Jorg Senn-Bilfinger
  • Patent number: 6436953
    Abstract: Compounds of formula (1) in which the substituents have the meanings mentioned in the description, are suitable for the prevention and treatment of gastrointestinal diseases.
    Type: Grant
    Filed: July 19, 2000
    Date of Patent: August 20, 2002
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Jörg Senn-Bilfinger
  • Patent number: 6436952
    Abstract: Compounds of the formula I, in which R1, R2, R3 and R4 have the meanings indicated in the description, are novel active bronchial therapeutics.
    Type: Grant
    Filed: February 15, 2001
    Date of Patent: August 20, 2002
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Dieter Flockerzi
  • Publication number: 20020090397
    Abstract: Acid-labile active compounds are prepared in suppository form, particularly for rectal administration.
    Type: Application
    Filed: March 13, 2002
    Publication date: July 11, 2002
    Applicant: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Rudolf Linder, Rango Dietrich
  • Patent number: 6410569
    Abstract: The invention relates to the dihydrate of the magnesium salt of pantoprazole.
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: June 25, 2002
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Bernhard Kohl
  • Patent number: 6410551
    Abstract: Compounds of formula I, in which R1, R2, R3, R31, R4, R5, R51 and R6 have the meanings indicated in the description, are efficacious bronchial therapeutics.
    Type: Grant
    Filed: December 23, 1999
    Date of Patent: June 25, 2002
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Beate Gutterer
  • Patent number: 6395732
    Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, and R3 are hydrogen, 1-4C-alkyl, or halogen; R4, R5, R6, and R9 are hydrogen or 1-4C-alkyl; R7 and R8 are hydrogen, 1-4C-alkyl, 1-4C-alkoxy, or halogen; A is 1-7C-alkylene, 2-7C-alkenylene, 3-7C-cycloalkylene, or phenylene; G is hydrogen, hydroxyl, 1-7C-alkyl, 1-4C-alkyl substituted by fluorine, 2-7C-alkenyl, 3-7C-cycloalkyl, a mono- or di-1-4C-alkylcarbamoyl or -thiocarbamoyl, N-1-4C-alkyl-N′-cyanoamidino, 1-N-1-4C-alkylamino-2-nitroethylene, N-2-propynyl-N′-cyanoamidino, aminosulfonylamidino, —N(R10)R11, the part of the compound of formula (I) bonded to A, glucopyranoside, or a cyclic system or bicyclic system which is optionally substituted by R12 and R13; X is oxygen, N-1-4C-alkyl, NH, or S; Y is oxygen, N-1-4C-alkyl, NH, S, 1,4-piperazinylene, or 1,4-piperidinylene; Z is oxygen, N-1-4C-alkyl, NH, S, or CO; m is from 1 to 7; n is from 0 to 4; t is 0, 1, or 2; and u is 0 or 1, and their salts suitable for controllin
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: May 28, 2002
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Peter Zimmermann, Gerhard Grundler
  • Patent number: 6384047
    Abstract: Compounds 8,9-diethoxy-2-methyl-6-[4(p-toluenesulfonamide) phenyl]-1,2,3,4,4a,10b-hexahydrobenzo[c][1,6]naphthyridine and 9-ethoxy-8-methoxy-2-methyl-6-[4-(p-toluenesulfonamido)phenyl]-1,2,3,4,4a,10b-hexahydrobenzo[c][1,6]naphthyridine and medicament compositions based thereon are useful for treating airway disorders, high blood pressure disorders and concomitant disorders connected therewith.
    Type: Grant
    Filed: December 3, 1999
    Date of Patent: May 7, 2002
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Dieter Flockerzi, Armin Hatzelmann
  • Patent number: 6384048
    Abstract: Tetrahydropyrido compounds of formula (I) in which the substituents have the meanings mentioned in the description, are suitable for the prevention or treatment of gastrointestinal diseases.
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: May 7, 2002
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Jörg Senn-Bilfinger
  • Patent number: 6383510
    Abstract: Acid-labile active compounds are prepared in suppository form, particularly for rectal administration.
    Type: Grant
    Filed: July 6, 2000
    Date of Patent: May 7, 2002
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Rudolf Linder, Rango Dietrich
  • Patent number: 6380196
    Abstract: Compounds of formula I, wherein Het represents a heterocycle having the meaning and R1, R2, R3 and R4 have the meanings as given in the description are novel effective bronchial therapeutics.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: April 30, 2002
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Wolf-Rüdiger Ulrich, Geert Jan Sterk, Margaretha van der Mey
  • Patent number: 6376485
    Abstract: Compounds of formula I in which R1, R2, R3 and A have the meaning set forth in the specification, are selective cyclic nucleotide phosphodiesterase (PDE) inhibitors useful as therapeutics in human and veterinary medicine. They are distinguished by low toxicity, good enteral absorption (high bioavailability), a wide therapeutic breadth and absence of significant side effects.
    Type: Grant
    Filed: January 3, 2001
    Date of Patent: April 23, 2002
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Thomas Martin
  • Publication number: 20020025342
    Abstract: Novel administration form for acid-labile active compounds are described. The novel administration forms have no enteric layers and are suitable for oral administration.
    Type: Application
    Filed: October 26, 2001
    Publication date: February 28, 2002
    Applicant: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Rudolf Linder, Rango Dietrich
  • Patent number: 6333354
    Abstract: A diseased state based on acute or chronic obstruction of vessels and/or bronchi, acute or chronic inflammation and/or edema formation is advantageously treated by the combined administration of a PDE inhibitor with either an adenylate cyclase agonist or a guanylate cyclase agonist to a subject in need of such therapy. Administration can be either concurrent or in either order.
    Type: Grant
    Filed: August 27, 1999
    Date of Patent: December 25, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Christian Schudt
  • Patent number: 6328993
    Abstract: Novel administration form for acid-labile active compounds are described. The novel administration forms have no enteric layers and are suitable for oral administration.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: December 11, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Rudolf Linder, Rango Dietrich