Patents Assigned to Center for Innovative Technology
  • Patent number: 5391846
    Abstract: With proper handling, Gallium-Indium-Tin eutectics are suitable for use as a substitute for mercury in switch applications. The eutectics should be acid washed to prevent oxidation of the metal components of the eutectic while in the switch housing and, further, the switch housing should be filled with an inert gas. Preventing oxidation ensures long term performance of the switch. In addition, provisions need to be made to prevent wetting of the switch housing by the eutectic. Experiments have shown that acid washing of metallic switch housings prior to adding the Gallium-Indium-Tin eutectic reduces or eliminates wetting by the eutectic. In addition, experiments have shown that coating the walls of the switch housing with a fluoropolymer coating prevents wetting by the eutectic.
    Type: Grant
    Filed: February 25, 1993
    Date of Patent: February 21, 1995
    Assignee: The Center for Innovative Technology
    Inventors: Larry T. Taylor, James Rancourt, Carlos Perry, Jr.
  • Patent number: 5387629
    Abstract: Polymers containing the phosphine oxide moiety are identified as being particularly useful in applications where resistance to atomic oxygen etching is required and in applications where second order nonlinear optical effects will be utilized. Particularly preferred polymers for these two applications include poly(arylene ether phosphine oxide)s (PEPOS), and novel PEPOS which include phenolphthalein sub-units and derivatives thereof have been prepared.
    Type: Grant
    Filed: July 30, 1993
    Date of Patent: February 7, 1995
    Assignees: The Center for Innovative Technology, Virginia Polytechnic Institute & State University, Virginia Tech Intellectual Properties, Inc.
    Inventors: James E. McGrath, Carrington D. Smith, Duane B. Priddy, Jr., Timothy Pickering
  • Patent number: 5382680
    Abstract: Allosteric hemoglobin modifier compounds having the general structural formula: ##STR1## wherein the R.sub.2, R.sub.3, R.sub.4, R.sub.5, and R.sub.6 moieties may be hydrogen, halogen or alkyl groups and may be the same or different, and wherein the R.sub.7 and R.sub.8 moieties may be hydrogen or methyl groups and may be the same or different.
    Type: Grant
    Filed: June 26, 1991
    Date of Patent: January 17, 1995
    Assignee: The Center for Innovative Technology
    Inventors: Donald J. Abraham, Ahmed Mehanna, Ramnarayan Randad
  • Patent number: 5381229
    Abstract: An optical interferometer comprises a multi-mode sapphire fiber as a high temperature sensor. One end of the sapphire fiber is coupled to a silica fiber and, in turn, to the sapphire fiber. The sapphire fiber sensor produces reference and sensor reflections that produce optical fringes at the output of a detector coupled to the silica optical fiber via an opto-coupler. The optical fringes are related to displacements of the sensor which, in turn, can provide an indirect measurement of pressure, strain or temperature of the surface.
    Type: Grant
    Filed: August 31, 1992
    Date of Patent: January 10, 1995
    Assignee: Center for Innovative Technology
    Inventors: Kent Murphy, Ashish Vengsarkar, Shari Feth, Richard Claus, Sridhar Gollapudi, Anbo Wang
  • Patent number: 5357040
    Abstract: Fine particles of semi-crystalline ketone-containing aromatic polymers (PEEK, PEKK, etc.) are produced by controlling the rate and conditions of hydrolysis of an amorphous polyarylketimine intermediate. The choice of acid and its concentrations affects the rate of ketimine hydrolysis and subsequent particle formation. In addition, zero or reduced amounts of agitation during hydrolysis has been found to promote the formation of smaller (submicron) sized particles which are spherical in shape, while greater amounts of agitation or shear stress applied during hydrolysis results in nonspherical, larger particles. Carbon fiber reinforced composites were made from aqueous suspensions of these particles that were dispersed or stabilized by a water soluble polymer.
    Type: Grant
    Filed: February 24, 1993
    Date of Patent: October 18, 1994
    Assignees: The Center for Innovative Technology, Virginia Polytechnic Institute & State University, Virginia Tech Intellectual Properties, Inc.
    Inventors: James E. McGrath, Keith R. Lyon, Richey M. Davis, Ann Texier, Atilla Gungor
  • Patent number: 5355417
    Abstract: An active noise control system using a compact sound source is effective to reduce aircraft engine duct noise. The fan noise from a turbofan engine is controlled using an adaptive filtered-x LMS algorithm. Single multi channel control systems are used to control the fan blade passage frequency (BPF) tone and the BPF tone and the first harmonic of the BPF tone for a plane wave excitation. A multi channel control system is used to control any spinning mode. The multi channel control system to control both fan tones and a high pressure compressor BPF tone simultaneously. In order to make active control of turbofan inlet noise a viable technology, a compact sound source is employed to generate the control field. This control field sound source consists of an array of identical thin, cylindrically curved panels with an inner radius of curvature corresponding to that of the engine inlet.
    Type: Grant
    Filed: October 21, 1992
    Date of Patent: October 11, 1994
    Assignees: The Center for Innovative Technology, Virginia Polytechnic Institute & State University, Virginia Tech Intellectual Properties, Inc.
    Inventors: Ricardo Burdisso, Chris R. Fuller, Walter F. O'Brien, Russell H. Thomas, Mary E. Dungan
  • Patent number: 5346830
    Abstract: An E. coli heterologous gene expression system comprising a multicopy expression vector comprising an F promoter from bacteriophage P2; and at least one copy of a DNA sequence comprising a delta gene from satellite P4 operably linked to a regulatable promoter on a different replicon is disclosed.
    Type: Grant
    Filed: March 8, 1993
    Date of Patent: September 13, 1994
    Assignee: The Center for Innovative Technology
    Inventor: Gail Christie
  • Patent number: 5339374
    Abstract: The fibers are bound together about 1 cm apart. An oxy-propane torch is used to heat the fibers so that they fuse together. At the same time, the two relatively movable translational stages to which the fibers are clamped are pulled apart to form a biconical tapered region in the fibers. The fibers are tapered until a desired coupling ratio is achieved. After the insertion loss is measured, the torch is reintroduced into the taper region and one side (e.g., the right side) of the taper region is rotated with a minimal increase in the taper length, i.e., the distance between the two stations is increased only enough to keep an even tension in the taper region.
    Type: Grant
    Filed: May 26, 1993
    Date of Patent: August 16, 1994
    Assignees: The Center for Innovative Technology, Virginia Polytechnic Institute & State University, Virginia Tech Intellectual Properties, Inc.
    Inventors: Kent A. Murphy, Michael F. Gunther, Richard O. Claus
  • Patent number: 5336485
    Abstract: Ionizable congeners of aromatic and aliphatic alcohols provide potent cytoprotective properties in vivo and in vitro. Alpha-tocopherol succinate, cholesteryl succinate, cholesteryl sulfate, dihydrocholesterol succinate, dihydrocholesterol sulfate, and ergosterol analogs are particularly good cytoprotective agents. In addition, the tris salts of these compounds have superior cytoprotective properties.
    Type: Grant
    Filed: March 10, 1993
    Date of Patent: August 9, 1994
    Assignees: Center for Innovative Technology, Virginia Commonwealth University
    Inventor: Marc W. Fariss
  • Patent number: 5333622
    Abstract: A custom-molded earplug (18) for swimming protection, hearing protection, and the like, is fabricated in situ by depositing a foaming material (14 or 24) within a person's ear (10 or 42) and allowing the foaming material to form foam (16 or 44). Acoustic and electronic equipment such as a Helmholtz resonator or other tuned device capable of modifying sound waves, a communications transmitter, a communications receiver, a communications transceiver, a hearing aid, an ear microphone, a personal earphone, and a hearing test transducer or probe tube can be fabricated in the ear in a similar fashion. Temperature sensing elements may also be incorporated within or positioned by the foaming material to provide an in the ear thermometer.
    Type: Grant
    Filed: July 17, 1992
    Date of Patent: August 2, 1994
    Assignee: The Center for Innovative Technology
    Inventors: John G. Casali, Daniel W. Mauney
  • Patent number: 5334520
    Abstract: Methods are provided for enhancing the production of PHB from a transformed E. coli host which includes the genes coding for the PHB biosynthetic pathway. By inserting the genes coding for PHB into a host which includes a lactose utilization system, a low cost minimal medium including whey can be used as the fuel and carbon source for PHB production. A plasmid which codes for the PHB biosynthetic pathway plus four hundred extra bases on either side of the first and last genes in the pathway has been inserted into the host and has been shown to produce a larger amount of PHB accumulation in a shorter period of time than other plasmid constructs. CaCl.sub.2 has been shown to be an effective agglomerating agent for agglomerating PHB which has been produced in a transformed E. coli host.
    Type: Grant
    Filed: May 25, 1990
    Date of Patent: August 2, 1994
    Assignee: Center for Innovative Technology
    Inventor: Douglas E. Dennis
  • Patent number: 5329439
    Abstract: A three-phase, pulse-width-modulated, switching rectifier, with zero-voltage-switching.
    Type: Grant
    Filed: June 15, 1992
    Date of Patent: July 12, 1994
    Assignee: Center for Innovative Technology
    Inventors: Dusan Borojevic, Fred C. Lee, Vlatko Vlatkovic
  • Patent number: 5328603
    Abstract: Improved cellulosic beads for use as supports in bioaffinity chromatography are produced by dissolution of cellulose in a chaotropic cellulose solvent, formation of the dissolved cellulose into droplets, and immersion of the droplets into a non-solvent capable of solvent interchange with the cellulose solvent to form generally spherical porous cellulose beads of narrow particle size distribution. The beads formed are preferably made with cellulose having a degree of polymerization between 100 and 200, and the resulting beads when saturated with water without drying contain between 1% and 7% cellulose by weight and have a particle size of at least about 0.3 mm. The beads can be activated by a suitable activation method, and specific bioaffinity ligands are bound to the active sites in the beads. The beads reacted ligands, the beads then used in bioaffinity chromatography to isolate specific bioaffinity molecules having molecular weights between 5,000 and 500,000 from complex solutions.
    Type: Grant
    Filed: August 19, 1992
    Date of Patent: July 12, 1994
    Assignee: The Center for Innovative Technology
    Inventors: William H. Velander, Jeffrey A. Kaster, Wolfgang G. Glasser
  • Patent number: 5327225
    Abstract: An optical fiber surface plasmon resonance (SPR) sensor includes both a metal layer and an overlay or underlay material on its surface. Existing fiber based SPR devices are inherently incapable of monitoring aqueous systems which have a refractive index ranging between 1.33 and 1.35, and existing prism based SPR sensors have proved too cumbersome for online chemical and biochemical analyses. Inclusion of the overlay or underlay material on the SPR sensor allows monitoring media with a refractive index from 1.00 to the 1.39 barrier and above. Hence, the SPR sensor allows monitoring important biochemical and chemical aqueous processes where the media typically have a refractive index between 1.33 and 1.35. In operation, samples are simply applied to the sensing region of the SPR sensor where the metal layer and overlay or underlay materials are coated, introducing a polarized beam of light into the optical fiber, and detecting surface plasmon resonance.
    Type: Grant
    Filed: January 28, 1993
    Date of Patent: July 5, 1994
    Assignee: The Center for Innovative Technology
    Inventors: William J. H. Bender, Raymond E. Dessy
  • Patent number: 5325283
    Abstract: An isolated zero-voltage-switching converter in which the magnetizing inductance of the isolating transformer is a resonant element and an open circuit is provided on the secondary side of the transformer during the time interval when both primary switches are off. When the secondary of the transformer is open, the magnetizing inductance is in series with the capacitances of the primary switches, thus forming a resonant circuit.
    Type: Grant
    Filed: June 8, 1992
    Date of Patent: June 28, 1994
    Assignee: Center for Innovative Technology
    Inventors: Richard W. Farrington, Milan M. Jovanovic, Fred C. Lee
  • Patent number: 5311957
    Abstract: A steering linkage in which a pair of steering arms rotatably mounted on the vehicle frame are jointed by a tie rod to form, in combination, a parallelogram. For each wheel, a steering arm slidably engages a crank arm secured to a king pin that rotatably mounts the wheel to the frame. The pivot point of each steering arm is arranged so that a given angular rotation of both steering arms produces a differential angular wheel rotation that maintains the point of intersection of the steered wheel axes proximate the axis of the fixed wheels or more generally, the rotational axis of all wheels proximate a fixed point.
    Type: Grant
    Filed: September 13, 1993
    Date of Patent: May 17, 1994
    Assignee: Center for Innovative Technology
    Inventors: Colin A. McLaurin, Kao-Chi Chung
  • Patent number: 5309767
    Abstract: A pressure sensor includes a liquid crystal positioned between transparent, electrically conductive films (18 and 20), that are biased by a voltage (V) which induces an electric field (E) that causes the liquid crystal to assume a first state of orientation. Application of pressure (P) to a flexible, transparent film (24) causes the conductive film (20) to move closer to or farther from the conductive film (18), thereby causing a change in the electric field (E'(P)) which causes the liquid crystal to assume a second state of orientation. Polarized light (P.sub.1) is directed into the liquid crystal and transmitted or reflected to an analyzer (A or 30). Changes in the state of orientation of the liquid crystal induced by applied pressure (P) result in a different light intensity being detected at the analyzer (A or 30) as a function of the applied pressure (P).
    Type: Grant
    Filed: October 9, 1992
    Date of Patent: May 10, 1994
    Assignee: Center for Innovative Technology
    Inventors: Devendra S. Parmar, Harlan K. Holmes
  • Patent number: 5309922
    Abstract: A respiratory sound analyzer system for use in the noisy ambient environments, such as in medical transport vehicles including helicopters, boats, aircraft, ambulances, and other vehicles, as well as at fire scenes, disasters, sporting events, rock concerts, and the like, includes an array of miniature accelerometers which are connected to the chest of a patient. Rather than relying on traditional auscultation, the on-board personnel will analyze a conditioned signal on a display screen or other device to monitor a patient's breathing patterns. Successive signals may be stored and compared with each other to determine a deterioration in a patient's breathing pattern, and signals may also be compared with stored normal and abnormal breathing signals. Ambient noise effects can be reduced or eliminated from the sensed breathing signal by a number of means.
    Type: Grant
    Filed: September 21, 1992
    Date of Patent: May 10, 1994
    Assignee: Center for Innovative Technology
    Inventors: Gary L. Schechter, Robert F. Coleman
  • Patent number: 5305645
    Abstract: A conventional dynamic testing machine, such as an MTS (Material Test System) is modified to allow for a new method for dynamically monitoring fatigue damage in a specimen. Load and stroke signals are used to determine phase angle and gain frequency response parameters for a specimen as it is cyclically loaded. Although the cycles required for specimens to fatigue to failure varies greatly from specimen to specimen, the phase shift between the load and stroke signals as well as the gain of the stroke signal remains fairly constant from specimen to specimen. These characteristic parameters can be used to accurately determine the percent of life remaining and residual strength in other specimens.
    Type: Grant
    Filed: May 4, 1992
    Date of Patent: April 26, 1994
    Assignee: The Center for Innovative Technology
    Inventors: Kenneth L. Reifsnider, Ahmad Razvan, Mehran Elahi
  • Patent number: 5301001
    Abstract: An extrinsic Fizeau fiber optic sensor comprises a single-mode fiber, used as an input/output fiber, and a multimode fiber, used purely as a reflector, to form an air gap within a silica tube that acts as a Fizeau cavity. The Fresnel reflection from the glass/air interface at the front of the air gap (reference reflection) and the reflection from the air/glass interface at the far end of the air gap (sensing reflection) interfere in the input/output fiber. The two fibers are allowed to move in the silica tube, and changes in the air gap length cause changes in the phase difference between the reference reflection and the sensing reflection. This phase difference is observed as changes in intensity of the light monitored at the output arm of a fused biconical tapered coupler. The extrinsic Fizeau fiber optic sensor behaves identically whether it is surface mounted or embedded, which is unique to the extrinsic sensor in contrast to intrinsic Fabry-Perot sensors.
    Type: Grant
    Filed: February 12, 1992
    Date of Patent: April 5, 1994
    Assignee: Center For Innovative Technology
    Inventors: Kent A. Murphy, Michael F. Gunther, Ashish M. Vengsarkar, Richard O. Claus