Patents Assigned to Centre National de la Recherche Scientifique (CRNS)
  • Patent number: 11464407
    Abstract: A method for generating an indicator or biomarker of colour perception in a mammalian subject, where the method may include submitting the mammalian subject to a multicoloured dynamic stimulus comprising displaying, on a display device. The method may include controlling a change over time of at least one of the two colours of the multicolour pattern when displaying the dynamic multicolour stimulus, to vary the displayed luminance of this colour (usually several times). The method may include acquiring, by using an image acquisition device, an oscillatory response of a pupil of the mammalian subject. The method may include generating, from the acquired response, a signal representative of the power of the pupil's oscillatory response as a function of the change over time of at least one of the two colours when displaying the dynamic multicoloured stimulus.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: October 11, 2022
    Assignees: INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE (ICM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CRNS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (AP-HP), SORBONNE UNIVERSITE
    Inventors: Pierre Pouget, Alexis Genin
  • Patent number: 9738712
    Abstract: The present invention relates to variable domain of a camelid heavy-chain antibodies directed to amyloid ? and conjugates thereof. The present invention also relates to the use of these antibody conjugates for treating or diagnosing disorders mediated by amyloid ? deposits.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: August 22, 2017
    Assignees: F. HOFFMAN-LA ROCHE AG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CRNS), INSTITUT PASTEUR, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Pierre Lafaye, Sylvie Bay, Benoit Delatour, Marc Dhenain, Charles Duyckaerts, Tengfei Li, Matthias Vandesquille, Christian Czech, Fiona Grueninger
  • Patent number: 9040934
    Abstract: This invention relates to a two-dimensional detection system for neutron radiation comprising a means (1) for emitting a neutron beam (10), a support means (2) adapted for receiving a sample (3), a photoemission means (5) adapted for being activated by a neutron radiation, a cooled low light level charge-coupled detection device (7). The emission means (1) emits a monochromatic neutron beam (10). The system further comprises a filter means (4), the filter means (4) being located between the support means (2) and the photoemission means (5) and being adapted for trapping at least a substantial part of the monochromatic neutron beam transmitted (12) by the sample (3), and an amplification means (6) located upstream the charge-coupled detection device (7) and coupled with the charge-coupled detection device (7).
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: May 26, 2015
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CRNS), COMMISSARIAT A L'ENERGIE ATOMIQUE
    Inventors: Patrick Francois Baroni, Laurence Marie Noirez
  • Publication number: 20120315194
    Abstract: The invention relates to a gas processing unit adapted for generating a surface plasma in the vicinity of a photocatalyst, that has a planar configuration. The photocatalyst is deposited in the form of a thin layer on a dielectric substrate and at least one plasma supply electrode is formed above the photocatalyst thin layer. Such a configuration increases the interaction between the plasma and the photocatalyst. The unit can be used for a gas processing of the pollution-control, odour reduction or bactericidal treatment type with a high efficiency.
    Type: Application
    Filed: January 6, 2010
    Publication date: December 13, 2012
    Applicants: Centre National De La Recherche Scientifique-CRNS-, Ecole Polytechnique
    Inventors: Antoine Rousseau, Katia Allegraud, Olivier Guaitella
  • Patent number: 7936233
    Abstract: The invention concerns a coaxial automatic impedance adaptor characterized in that it comprises two slugs and has only a lateral translational movement along an axis Ox. The double slug tuner principle is based on the movement of two line segments of different characteristics of 50 O inside a closed cylinder on either side of standard connectors.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: May 3, 2011
    Assignees: Centre National de la Recherche Scientifique - CRNS, Universite des Sciences et Technologies de Lille - USTL
    Inventors: Nicolas Vellas, Christophe Gaquière, Frédéric Bue, Damien Ducatteau
  • Publication number: 20100239466
    Abstract: The invention relates to a gas processing unit adapted for generating a surface plasma in the vicinity of a photocatalyst, that has a planar configuration. The photocatalyst is deposited in the form of a thin layer on a dielectric substrate and at least one plasma supply electrode is formed above the photocatalyst thin layer. Such a configuration increases the interaction between the plasma and the photocatalyst. The unit can be used for a gas processing of the pollution-control, odour reduction or bactericidal treatment type with a high efficiency.
    Type: Application
    Filed: January 6, 2010
    Publication date: September 23, 2010
    Applicants: Ecole Polytechnique, Centre National De La Recherche Scientifique -CRNS-
    Inventors: Antoine Rousseau, Katia Allegraud, Olivier Guaitella
  • Patent number: 7754425
    Abstract: The subject of the present invention is a process for aligning a macromolecule (macromolecules) on the surface S of a support, characterized in that the triple line S/A/B (meniscus) resulting from the contact between a solvent A and the surface S and a medium B is caused to move on the said surface S, the said macromolecules having a part, especially an end, anchored on the surface S, the other part, especially the other end, being in solution in the solvent A. The subject of the present invention is also a process for detecting, measuring the intramolecular distance of, separating and/or assaying a macromolecule in a sample in which a process of alignment according to the invention is used.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: July 13, 2010
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique (CRNS)
    Inventors: David Bensimon, Aaron Bensimon, François Heslot
  • Publication number: 20100121443
    Abstract: The invention relates to a device (1) for the vision correction of an eye (6), comprising: a converter (3, 3A, 3B, 5A, 5B) which can generate an electrical and/or magnetic and/or electromagnetic signal in response to the mechanical energy generated by a movement of the eye; and a soft lens (2) intended to be aligned with the eye. The converter is positioned in relation to the lens such that the electrical and/or magnetic and/or electromagnetic signal generated during the movement of the eye causes the optical properties of the lens to change. The invention is characterised in that the lens (2) includes a polymer material (7) containing a material (4) having a refractive index that can vary under the action of the electrical and/or magnetic and/or electromagnetic signal generated during a movement of the eye.
    Type: Application
    Filed: February 8, 2008
    Publication date: May 13, 2010
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE- CRNS
    Inventors: Francois Michel, Jean-Marc Buisine