Patents Assigned to Centre National de la Recherche Scientique
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Publication number: 20210277191Abstract: A subtractive method for structuring a hydrogel, comprising the following steps: producing a hydrogel layer containing benzophenone (3) on a substrate (6), the hydrogel not having any photocleavable group; bringing the hydrogel layer into contact with an oxygen tank (4); selectively illuminating the hydrogel layer with a light (5) capable of activating the benzophenone in order to convert the illuminated zone of the hydrogel layer into a liquid; and eliminating the liquid.Type: ApplicationFiled: June 27, 2019Publication date: September 9, 2021Applicants: ALVEOLE, Centre National de la Recherche Scientique, Université de BordeauxInventors: Vincent Studer, Aurélien Pasturel
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Publication number: 20210060515Abstract: Product for printing proteins comprising a substrate (1), a nanoscale polymer first layer (3), which is nonstick for the proteins, deposited on the substrate (1), and a second layer of a benzophenone (2), deposited on the first layer (3), wherein the second layer (2) is solid and soluble in a solvent, and the first layer (3) is insoluble in the solvent.Type: ApplicationFiled: March 19, 2019Publication date: March 4, 2021Applicants: ALVEOLE, Centre National de la Recherche Scientique, Université de BordeauxInventors: Vincent Studer, Louise Bonnemay
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Patent number: 10906016Abstract: The present invention relates to the field of manufacturing nanoparticles, and specifically to a method for manufacturing diamond nanoparticles, or nanodiamonds, by detonation at least one explosive charge, wherein said at least one explosive charge is nanostructured.Type: GrantFiled: February 28, 2013Date of Patent: February 2, 2021Assignees: ISL—Institut Franco-allemand de recherches de Saint-Louis, CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (C.N.R.S.)Inventors: Denis Spitzer, Vincent Pichot, Benedikt Risse
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Patent number: 10596264Abstract: The invention relates to LAH4 peptides and functional derivatives thereof and their use for improving transduction efficiency of viruses into target cells.Type: GrantFiled: June 28, 2012Date of Patent: March 24, 2020Assignees: Genethon, Centre National de la Recherche Scientique, Institut National de la Sainte et de la Recherche MadicaleInventors: David Fenard, Antoine Kichler, Samia Martin
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Publication number: 20190001252Abstract: A subject of the present invention is the use of a compound having the general formula (I): (I) wherein V, W, X4, X5, X6, X7, X?4, X?5, X?6, X?7, Y, Y?, R3, R?3, R4 and R?4 are as defined in any one of claims 1 to 11, for the detection, capture and/or separation of polluting gases, in particular those selected from the group comprising carbon dioxide, methane, sulfur dioxide, nitrogen oxides, carbon monoxide, linear hydrocarbons, linear mono-olefins and their mixtures, and preferably carbon dioxide. Another subject of the invention is a compound of formula (I) wherein V, W, X4, X5, X6, X7, X?4, X?5, X?6, X?7, Y, Y?, R3, R?3, R4 and R?4 are as defined in any one of claims 12 to 21.Type: ApplicationFiled: December 23, 2016Publication date: January 3, 2019Applicants: Centre National de la Recherche Scientique -CNRS-, Université d'Aix-MarseilleInventors: Jean-Manuel Raimundo, Vinicius Demétrio da Silva, Philip Leslie Llewellyn, Julien Rodriguez, Olivier Yves Claude Siri
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Patent number: 9611320Abstract: The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. The present disclosure is further directed to methods comprising detection of progastrin, including methods of diagnosing colorectal cancer and methods of monitoring efficacy of anti-cancer therapy in subjects suffering from colorectal cancer.Type: GrantFiled: October 15, 2010Date of Patent: April 4, 2017Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (CNRS), LES LABORATOIRES SERVIERInventors: Julie Pannequin, Laure Boudier, Dominique Joubert, Frédéric Hollande
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Patent number: 9487582Abstract: The present disclosure is directed to methods of treating pancreatic cancer in subject using cancer with antibodies that specifically bind to progastrin.Type: GrantFiled: January 4, 2011Date of Patent: November 8, 2016Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (CNRS), LES LABORATORIES SERVIERInventors: Leïla Houhou, Dominique Joubert, Frédéric Hollande
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Publication number: 20150189844Abstract: The invention relates to a method for obtaining a plant in which a homologous recombination event has occurred, preferably resulting in targeting gene insertion in the genome of said plant, by regeneration of the plant from in vitro culture.Type: ApplicationFiled: July 19, 2013Publication date: July 9, 2015Applicants: Biogemma, Centre National de la Recherche Scientique, Université Blaise Pascal, Université d'AuvergneInventors: Wyatt Paul, Ayhan Ayar, Charles White, Maria-Eugenia Gallego
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Publication number: 20150184122Abstract: A guiding device in which cells are confined between a support surface and a textured surface of a substrate, said textured surface having an anisotropic three-dimensional structure having a repeating pattern that repeats according to a repeat axis, said repeating pattern having a succession of guide spaces adjacent to one another according to the repeat axis, each of said guide spaces being capable of receiving at least one portion of one of the cells and being oriented according to a direction of anisotropy to guide a movement of the cells in the direction of anisotropy.Type: ApplicationFiled: September 17, 2012Publication date: July 2, 2015Applicants: Institut Curie, Centre National de la Recherche Scientique - CNRS, Societe de Developpement et de Recherche IndustrielleInventors: Maël Le Berre, Matthieu Piel, Yanjun Liu
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Publication number: 20150157997Abstract: The present invention relates to the field of manufacturing nanoparticles, and specifically to a method for manufacturing diamond nanoparticles, or nanodiamonds, by detonation at least one explosive charge, wherein said at least one explosive charge is nanostructured.Type: ApplicationFiled: February 28, 2013Publication date: June 11, 2015Applicants: ISL - Institut Franco-allemand de recherches de Saint-Louis, CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (C.N.R.S.)Inventors: Denis Spitzer, Vincent Pichot, Benedikt Risse
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Publication number: 20150153471Abstract: An electromagnetic system for exploring the seabed in a marine environment includes a current injection module with two electrodes spaced apart from one another, said injection electrodes being capable of injecting a current at a predetermined voltage into the marine environment close to the seabed, said injection electrodes having a contact surface with the marine environment. The system includes a data acquisition module with at least two measuring sensors for measuring electrical or magnetic data at at least two points of the marine environment close to the seabed, and a power supply module for supplying power to the current injection module. Each electrode includes one or more separate conductive elements that are electrically connected to each other and arranged in such a way as to form a conductive network or a multilayer conductive assembly having a large contact surface with the marine environment.Type: ApplicationFiled: January 9, 2013Publication date: June 4, 2015Applicants: UNIVERSITE DE BRETAGNE OCCIDENTALE - UBO, CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE - CNRSInventors: Jean-François D'eu, Pascal Tarits, Fabien Gaspari
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Publication number: 20150068131Abstract: A process for manufacturing an abrasive wire formed by abrasive particles held on a central core by a binder comprises depositing abrasive particles on the central core, each particle comprising a magnetic material that has a relative permeability greater than 50 and that represents at least 1% of the volume of the abrasive particle, and depositing binder on the central core to keep the abrasive particles attached to it. The core has south poles and north poles alternating along either its circumference or its length.Type: ApplicationFiled: March 29, 2013Publication date: March 12, 2015Applicants: Commissarial a renergie atomique et aux energies alternatives, Thermocompact, CEntre NAtional de la Recherche ScientiqueInventors: Gérald Sanchez, Michel Ly, Sophie Rivoirard, Arnaud Grifford
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Publication number: 20150060737Abstract: The invention relates to novel block copolymers that enable a good dispersion of nanofillers in water and also to a dispersion of nanofillers obtained owing to these block copolymers. This dispersion may be used as a transparent electrode in organic solar cells or other photoemitter or photoreceptor devices.Type: ApplicationFiled: April 3, 2013Publication date: March 5, 2015Applicants: Arkema France, Centre National De La Recherche Scientique, Universite De Bordeaux 1, Institut Polytechnique De BordeauxInventors: Christophe Navarro, Katerina Bethani, Cyril Brochon, Henri Cramail, Guillaume Fleury, Georges Hadziioannou, Eric Cloutet
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Publication number: 20140374343Abstract: A device for purifying liquid wastewater, includes: a container suitable for retaining a granulate consisting of solid particles, and for enabling the contact between the solid particles of the granulate and the liquid wastewater flowing in the container between: an inlet for the liquid wastewater to flow into the container, and an outlet for substantially decontaminated water to flow out of the container; a community of microorganisms extending so as to be in contact with the solid particles of the granulate; at least one live benthic invertebrate whose mean size is greater than 250 ?m and which is distributed in the granulate; and at least one live benthic invertebrate whose mean size is from 50 ?m to 250 ?m and which is distributed in the granulate, characterized in that the community of macrobenthic organism and meiobenthic organism species includes a proportion of 60% to 80% of invertebrate detrivorous organisms.Type: ApplicationFiled: January 8, 2013Publication date: December 25, 2014Applicants: INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE, UNIVERSITE PAUL SABATIER (TOULOUSE III), CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (C.N.R.S.)Inventors: Magali Gerino, Philippe Vervier, Jose Miguel Sanchez Perez, Laury Gauthier
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Publication number: 20140305809Abstract: The present invention relates to mutants of the Penicillium amagasakiense glucose oxidase (GOx) enzyme which are of use for assaying glucose and to the development in particular of glucose electrodes and of biocells which use glucose as fuel.Type: ApplicationFiled: September 7, 2012Publication date: October 16, 2014Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUEInventors: Nicolas Mano, Olivier Courjean, Emilie Tremey, Sebastien Gounel
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Publication number: 20140255349Abstract: The invention relates to peptides and functional derivatives thereof and their use for improving transduction efficiency of viruses into target cells.Type: ApplicationFiled: June 28, 2012Publication date: September 11, 2014Applicants: GENETHON, Institut National de la Sainte et de la recherche Madicale, Centre National de la Recherche ScientiqueInventors: David Fenard, Antoine Kichler, Samia Martin
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Publication number: 20140248324Abstract: The novel biomaterial fillers containing cross-linked sodium alginate and the method for manufacturing same are used in the medical field and are intended for filling tissue lesions having a layered structure of varying compositions, such as cartilage, skin or the epithelium. These novel biomaterials have the special feature of being multiphasic, composite and functionalized, for medical use and, in particular, for treating tissue lesions having a layered structure of varying compositions. The biomaterials are particularly suitable for treating focal lesions of the articular cartilage.Type: ApplicationFiled: April 24, 2012Publication date: September 4, 2014Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE, UNIVERSITE DE LORRAINEInventors: Laurent Jacques Grossin, Jean-Claude Voegel, Pierre Gilbert Schaaf, Pierre Gillet, Christel Odette Henrionnet, Patrick Netter
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Publication number: 20140228460Abstract: An interconnected microcellular material, a method for preparing said material using low-value waste from the paper industry, such as industrial lignin, and the use thereof for the production of items such as catalysts, filters or absorbent elements.Type: ApplicationFiled: September 27, 2012Publication date: August 14, 2014Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (CNRS), UNIVERSITE DE BORDEAUXInventors: Herve Deleuze, Claire Forgacz, Marc Birot
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Publication number: 20130177488Abstract: A simple, inexpensive and non-corrosive industrial separation method making it possible to separate zirconium and hafnium tetrachlorides from mixtures thereof, a simple industrial method allowing the zirconium/hafnium separation, and a method making it possible to produce fractions enriched with zirconium and containing hafnium at a trace level are disclosed.Type: ApplicationFiled: August 2, 2011Publication date: July 11, 2013Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUEInventors: Catherine Santini-Scampucci, Yves Chauvin, Paul Campbell
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Publication number: 20110097479Abstract: The present invention concerns electrode materials capable of redox reactions by electrons and alkali ions exchange with an electrolyte. The applications are in the field of primary (batteries) or secondary electrochemical generators, super capacitors and light modulating system of the super capacitor type.Type: ApplicationFiled: November 22, 2010Publication date: April 28, 2011Applicants: ACEP Inc., Centre National De La Recherche Scientique, Universite De MontrealInventors: Nathalie Ravet, Simon Besner, Martin Simoneau, Alain Vallee, Michel Armand, Jean-Francois Magnan