Patents Assigned to Chugai Pharamceutical Co.
  • Inhibitors of bruton's tyrosine kinase
    Patent number: 9802920
    Abstract: This application discloses compounds according to generic Formula (I): wherein all variables are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are useful for the treatment of oncological, auto-immune, and inflammatory diseases caused by aberrant B-cell activation. Also disclosed are compositions containing compounds of Formula I and at least one carrier, diluent or excipient.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: October 31, 2017
    Assignees: Hoffman-La Roche Inc., Chugai Pharamceutical Co.
    Inventors: Romyr Dominique, Norman Kong, Yan Lou, Francisco Javier Lopez-Tapia, Sung-Sau So