Patents Assigned to Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET)
  • Patent number: 10995610
    Abstract: Tracers for oil recovery, particularly fluorescent nanotracers conservative in aqueous phases. The tracer comprises a core-shell nanoparticle tailored according to the operation to be traced. It contains a fluorescent core that allows the detection thereof in the field and a functionalized polymeric shell that provides increased stability in high salinity aqueous phases. A method for preparing said nanotracer. Given the nanotracer versatility, it can be used both for tracing fracking steps as well as meshes of secondary and tertiary recovery.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: May 4, 2021
    Assignees: YPF Technologia S.A., Consejo Nacional De Investigaciones Científicas Y Técnicas (Conicet)
    Inventors: Alejandra Calvo, María Laura Vera, María Laura Dell'Archiprete, Melina Vanesa Cozzarin, Juan Martín Giussi, Mónica Gonzalez, Félix Gregorio Requejo, Omar Azzaroni
  • Patent number: 10857522
    Abstract: A process for producing propylene glycol from glycerol including a catalyst of Cu and Ce at concentrations of up to 15% of each metal. In addition, it is described a catalyst of Cu and Ce to perform the selective reduction of glycerol and the process of production of such catalyst.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: December 8, 2020
    Assignees: CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET), UNIVERSIDAD NACIONAL DEL LITORAL, INIS BIOTECH LLC.
    Inventors: Raul Alberto Comelli, Lisandro Roberto Ferrari
  • Patent number: 10822612
    Abstract: The present invention relates to a method of enhancing the activity of a transcription factor in a plant comprising expressing in said plant a chimeric protein comprising a GIF moiety comprising a GIF domain or fragment thereof, and a DNA binding domain (DBD) moiety. The chimeric proteins comprise a GIF moiety comprising a GIF domain or fragment thereof, or a polypeptide with an amino acid sequence having at least 85%, preferably at least 90%, even more preferably at least 95% sequence identity to the amino acid sequence of a GIF domain or fragment thereof; and a DBD moiety comprising the DBD or plant transcription factor whose activity enhancement is intended, or a binding protein which is capable of forming a tertiary complex with the DBD or transcription factor whose activity modification and/or enhancement is intended. The invention also relates to polynucleotides and polypeptides useful in the method of the invention.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: November 3, 2020
    Assignees: CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET), UNIVERSIDAD NACIONAL DE ROSARIO
    Inventors: Carla Schommer, Javier Palatnik, Juan Manuel Debernardi, Ramiro Esteban Rodriguez Virasoro
  • Patent number: 10608246
    Abstract: The present invention is directed to an anode for a lithium-ion battery and a method of manufacturing the same. The anode is manufactured from a material composed of Si and C known as SBA-15/C having a porous structure of mesopores interconnected by micropores, wherein carbon nanofibers occupy the pore space of the porous structure. The anode has improved conductivity properties and allows to mitigate the drawbacks linked to the volumetric expansion of the anode during the operation of a lithium-ion battery.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: March 31, 2020
    Assignees: YPF TECHNOLOGIA S.A., CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET), UNIVERSIDAD NACIONAL DE CÓRDOBA
    Inventors: German Lener, Ezequiel Leiva, Daniel Barraco Diaz, Manuel Otero
  • Patent number: 10490866
    Abstract: A method for the acid dissolution of LiCoO2 contained in the cathode of lithium ion batteries, using acetic or tartaric acid as leaching agent, the method being characterized in that it comprises a first stage and a second stage, wherein said first stage comprises the step of separating the cathode components, while said second stage comprises the step of dissolving the pure LiCoO2 with at least one acid. The method allows achieving an economically viable complete recycling process with low environmental impact.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: November 26, 2019
    Assignees: CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET), UNIVERSIDAD NACIONAL DE CUYO, INIS BIOTECH LLC
    Inventors: Mario Humberto Rodriguez, Daniela S. Suarez, Eliana G. Pinna, Celina N. Zeballos
  • Patent number: 10456465
    Abstract: The present invention is based, in part, on the discovery that galectin-1 (Gal1) plays a role in viral-associated PTLD, e.g., EBV-associated PTLD and hypoxia associated angiogenesis disorders. Accordingly, the invention relates to compositions, kits, and method for diagnosing, prognosing, monitoring, treating and modulating viral-associated PTLD, e.g., EBV-associated PTLD and hypoxia associated angiogenesis disorders.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: October 29, 2019
    Assignees: Dana-Farber Cancer Institute, Inc., The Brigham and Women's Hospital, Inc., Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Fundacion Sales
    Inventors: Margaret A. Shipp, Jing Ouyang, Kunihiko Takeyama, Jeffery L. Kutok, Scott J. Rodig, Gabriel Rabinovich, Diego Omar Croci Russo, Mariana Salatino
  • Patent number: 10385114
    Abstract: The invention relates to the identification of Secreted Protein, Acidic and Rich in Cysteine (SPARC) as a new therapeutic target in patients with fulminant hepatitis and allows the development of a strategy destined to protect the liver form damage. The invention relates to the treatment of acute liver failure or fulminant hepatitis by administering to a subject in need thereof an agent that inhibits at least partially the expression of SPARC and/or interferes with its biological function.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: August 20, 2019
    Assignees: INIS BIOTECH LLC, CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET), FUNDACION INSTITUTO LELOIR (FIL), ASOCIACION CIVIL DE ESTUDIOS SUPERIORES (ACES)
    Inventors: Guillermo Daniel Mazzolini, Estanislao Peixoto, Jorge Aquino, Maria C. Atorrasagasti, Osvaldo Podhjacer
  • Publication number: 20190240406
    Abstract: A method for controlling an insulin injection device and a system for delivering insulin in a patient in need thereof. The method includes the steps of defining a time interval; receiving the level of blood glucose; computing an insulin dose to be injected in the next time interval, and transmitting the computed insulin dose to be injected to the insulin injection device.
    Type: Application
    Filed: October 13, 2017
    Publication date: August 8, 2019
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ÉCOLE CENTRALE DE NANTES, CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES, UNIVERSITÉ DE NANTES, CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET), INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)
    Inventors: Claude MOOG, Nicolas MAGDELAINE, Santiago RIVADENEIRA, Lucy CHAILLOUS, Michel KREMPF
  • Patent number: 10119145
    Abstract: The present disclosure provides engineered microorganisms, engineered biosynthetic pathways, methods of producing lipid compounds using genetically engineered microorganisms, and the products synthesized by those organisms. In particular, the disclosure provides genetically engineered microorganisms for the production of multi-methyl branched fatty acids (MMBFAs) and MMBFA esters (wax esters) derived from these fatty acids. In addition, the disclosure provides methods for producing acylglycerols with one of more of their acyl substituents being an MMBFA, and methods for producing alcohols derived from MMBFAs (fatty alcohols).
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 6, 2018
    Assignee: CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)
    Inventors: Hugo Gramajo, Ana Arabolaza, Santiago Comba, Simón Menendez-Bravo, Héctor Álvarez
  • Publication number: 20180147556
    Abstract: Bi-structured matrix for purification and handling of solid reagents, which comprises at least a polymer solid carrier coated with at least one hydrosoluble polymer, and manufacturing processes. The solid carrier may be, among others, cross-linked polyurethane foam or a micropipette tip. The hydrosoluble polymer may be, among others, polyvinylalcohol, agarose, hydroxyethylcellulose or combinations thereof. The matrix may further comprise a polymer produced from monomers of glycidyl metacrylate (GMA), dimethyl acrylamide (DMAAm), 2-hydroxyethyl metacrylate, metacrylic acid, or combinations thereof.
    Type: Application
    Filed: December 11, 2015
    Publication date: May 31, 2018
    Applicants: CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET), UNIVERSIDAD NACIONAL DE QUILMES, INIS BIOTECH LLC
    Inventors: Mirna SANCHEZ, Mariano GRASSELLI, Leandro J. MARTINEZ
  • Patent number: 9896695
    Abstract: The present invention provides isolated HaHB11 polypeptides and nucleic acids encoding the same. Also provided are methods of introducing a nucleic acid encoding HaHB11 polypeptides into a plant cell, plant part or plant, e.g., to increase tolerance to abiotic stress, to delay development and/or prolong the life span of a plant, and/or to increase yield from the plant. The invention also provides nucleic acids comprising HaHB11 promoter sequences and methods for expressing a nucleotide sequence of interest operably associated with the HaHB11 promoters of the invention in a plant cell, plant part, or plant. Also provided are transformed plants, plant tissues, plant cells and plant seed comprising the nucleic acids, expression cassettes and vectors of the invention.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: February 20, 2018
    Assignees: Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Universidad Nacional del Litoral (UNL)
    Inventors: Raquel Lia Chan, Julieta Virginia Cabello, Jorge Ignacio Giacomelli
  • Publication number: 20170362601
    Abstract: The present invention relates to a method of enhancing the activity of a transcription factor in a plant comprising expressing in said plant a chimeric protein comprising a GIF moiety comprising a GIF domain or fragment thereof, and a DNA binding domain (DBD) moiety. The chimeric proteins comprise a GIF moiety comprising a GIF domain or fragment thereof, or a polypeptide with an amino acid sequence having at least 85%, preferably at least 90%, even more preferably at least 95% sequence identity to the amino acid sequence of a GIF domain or fragment thereof; and a DBD moiety comprising the DBD or plant transcription factor whose activity enhancement is intended, or a binding protein which is capable of forming a tertiary complex with the DBD or transcription factor whose activity modification and/or enhancement is intended. The invention also relates to polynucleotides and polypeptides useful in the method of the invention.
    Type: Application
    Filed: December 16, 2015
    Publication date: December 21, 2017
    Applicants: CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET), UNIVERSIDAD NACIONAL DE ROSARIO
    Inventors: Carla SCHOMMER, Javier PALATNIK, Juan Manuel DEBERNARDI, Ramiro Esteban RODRIGUEZ VIRASORO
  • Publication number: 20170354957
    Abstract: A process for producing propylene glycol from glycerol including a catalyst of Cu and Ce at concentrations of up to 15% of each metal. In addition, it is described a catalyst of Cu and Ce to perform the selective reduction of glycerol and the process of production of such catalyst.
    Type: Application
    Filed: December 16, 2015
    Publication date: December 14, 2017
    Applicants: CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET), UNIVERSIDAD NACIONAL DEL LITORAL, INIS BIOTECH LLC
    Inventors: Raul Alberto COMELLI, Lisandro Roberto FERRARI
  • Patent number: 9801927
    Abstract: The invention relates to pharmaceutical compositions using a polypeptide comprising at least one CXXC motif, such as Giardia parasite's variable surface proteins (VSP) or a fragment thereof to raise by oral or mucosal vaccination an immune response against a heterologous selected antigen, such as tumor antigen, microbial antigen or other antigen.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: October 31, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), ASSITANCE PUBLIQUE HOPITAUX DE PARIS, CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET), UNIVERSIDAD CATOLICA DE CORCOBA (UCC)
    Inventors: David Klatzmann, Eliane Piaggio, Hugo Daniel Luján
  • Patent number: 9737515
    Abstract: The present invention relates to compositions and methods for preventing and treating cell proliferation in cancer. More specifically, the present invention relates to compositions and methods for inhibiting tumor growth, and for treating proliferative diseases, particularly colon and breast cancer, with a combined pharmacological approach. Yet more specifically, the compositions for inhibiting tumor growth comprise a combination of: i) a first component which is an ACSL4 inhibitor; and ii) a second component selected from the group consisting of mTOR inhibitor and ER inhibitor.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: August 22, 2017
    Assignee: Consejo Nacional De Investigaciones Cientificas Y Tecnicas (CONICET)
    Inventors: Ernesto Jorge Podesta, Paula Mariana Maloberti, Ulises Daniel Orlando, Melina Andrea Dattilo, Ana Fernanda Castillo, Angela Rosaria Solano
  • Patent number: 9657298
    Abstract: Recombinant bacterial strains comprising heterologous nif genes in its genome, and capable of fixing nitrogen. The strain may be, for example, a recombinant Pseudomonas fluorescens strain comprising heterologous nif genes in its genome. An inoculum and a method for increasing plant productivity are further described.
    Type: Grant
    Filed: November 22, 2012
    Date of Patent: May 23, 2017
    Assignees: CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET), INSTITUTO NACIONAL DE TECNOLOGIA AGROPECUARIA (INTA), INIS BIOTECH LLC
    Inventors: Gabriela Cynthia Soto, Sr., Nicolas Daniel Ayub, Lorena Maria Setten
  • Patent number: 9534025
    Abstract: Polypeptide having activity inducing pathogen plant defence, nucleotide sequence encodes it, microorganism, compositions and methods. The polypeptide is a subtilisin derived from a strain of Acremonium strictum. The polypeptide is encoded by the nucleotide sequence SEQ ID NO: 1 or sequences at least 90% homologous to the same and has the amino acid sequence SEQ ID NO: 2 or sequences at least 90% homologous to the same.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: January 3, 2017
    Assignees: UNIVERSIDAD NACIONAL DE TUCUMAN, CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)
    Inventors: Atilio Pedro Castagnaro, Juan Carlos Diaz Ricci, Nadia Regina Chalfoun, Josefina Racedo, Sergio Miguel Salazar
  • Patent number: 9427458
    Abstract: The present invention concerns methods of treating cancer and methods of inhibiting cancer cell proliferation, particularly methods of treating breast cancer, wherein the methods comprise delivering a dominant-negative inhibitor of endogenous ErbB-2.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: August 30, 2016
    Assignee: Consejo Nacional de Investigaciones Cientificas y Tecnicas, Conicet
    Inventor: Patricia V. Elizalde
  • Patent number: 9357786
    Abstract: Polypeptide having activity inducing pathogen plant defense, nucleotide sequence encodes it, microorganism, compositions and methods. The polypeptide is a subtilisin derived from a strain of Acremonium strictum. The polypeptide is encoded by the nucleotide sequence SEQ ID NO: 1 or sequences at least 90% homologous to the same and has the amino acid sequence SEQ ID NO: 2 or sequences at least 90% homologous to the same.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: June 7, 2016
    Assignees: UNIVERSIDAD NACIONAL DE TUCUMAN, CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)
    Inventors: Atilio Pedro Castagnaro, Juan Carlos Diaz Ricci, Nadia Regina Chalfoun, Josefina Racedo, Sergio Miguel Salazar
  • Patent number: 9255071
    Abstract: A pharmaceutically acceptable salt, prodrug or derivative compound of the formula I, wherein R1 is selected from H, a (C1-C5) alkyl group and a COR4 group; R2 is selected from H, a (C1-C5) alkyl group and a COR5 group; R3 is selected from H, a (C1-C5) alkyl group, a (C1-C5)-O-alkyl group, a cycloalkyl of (C5-C6) carbon atoms, an aryl group, and an aryl (C1-C5) alkyl group wherein the aryl group can be an unsubstituted aryl or substituted with one or more R6 groups and an NHCOR5 group, or the R2 and R3 groups together with N may form a piperidine, morpholine or piperazine group; R4 is selected from H and a (C1-C5)alkyl group; R5 is selected from an aryl group unsubstituted or substituted with one or more R6, linear or branched(C1-C5) alkyl or pyridyne groups and a pyridine group; R6 is selected from (C1-C5)alkyl groups, halogen and nitro.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: February 9, 2016
    Assignees: Consejo Nacional de Investigaciones Cientificas y Técnicas (CONICET), Laboratorios Richmond Sociedad Anónima Comercial Industrial y Financiera
    Inventors: Gerardo Burton, Fernando Javier Duran, Mario David Martinez, Elvira Zini, Veronica Mora Munoz, Lucila Bertoncello