Patents Assigned to CorMatrix Cardiovascular, Inc.
  • Patent number: 9066993
    Abstract: A remodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch having an internal region configured to receive a device therein, the bioremodelable material comprising an extracellular matrix (ECM) composition that includes an ECM scaffold component derived from a mammalian source and at least a bioactive component selected from the group consisting of a statin and a chitin derivative.
    Type: Grant
    Filed: September 24, 2012
    Date of Patent: June 30, 2015
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Patent number: 9060969
    Abstract: Disclosed herein are compositions and methods for treating or preventing a cardiac arrhythmia in a subject.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: June 23, 2015
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Patent number: 9044319
    Abstract: Anchored cardiovascular valves having a support member with at least one leaflet formed therein that is sized and configured to selectively restrict regurgitating blood through the valve, and at least one anchoring mechanism. In a preferred embodiment of the invention, the anchored valves have two anchoring mechanisms, i.e. proximal and distal anchoring mechanisms.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: June 2, 2015
    Assignee: Cormatrix Cardiovascular, Inc.
    Inventor: Robert Matheny
  • Patent number: 9034647
    Abstract: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: May 19, 2015
    Assignee: CORMATRIX CARDIOVASCULAR, INC.
    Inventor: Robert G Matheny
  • Patent number: 9034367
    Abstract: The invention is to articles made from extracellular matrix sheets that encase biodegradable polymeric material. Methods of healing wounds or regenerating tissue at sites of defect by placing said articles in mammals are claimed. The biodegradable polymer can change quality upon contact with a physiological parameter such as temperature or pH that causes, for example, a liquid polymer to gel or harden. The degradation of the polymer can be controlled to suit a tissue regeneration or wound healing time course. Additional components such as proteins, cells and drugs can be added to the biopolymer composition.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: May 19, 2015
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventors: Robert G. Matheny, Beecher C. Lewis
  • Patent number: 9011526
    Abstract: A seamless prosthetic valve having an outer abluminal surface, a triple walled intermediate portion, and at least one valve leaflet that is configured to selectively restrict fluid flow through the valve, the valve leaflet being formed by suturing the triple walled intermediate portion at a first commissure connection point.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: April 21, 2015
    Assignee: CorMatrix Cardiovascular, Inc
    Inventor: Robert G Matheny
  • Patent number: 8980296
    Abstract: Disclosed herein are compositions and methods for treating or preventing cardiac arrhythmia in a subject.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: March 17, 2015
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventors: Robert G. Matheny, Beecher C. Lewis
  • Patent number: 8877224
    Abstract: Disclosed herein are compositions and methods for treating or preventing a cardiac arrhythmia in a subject.
    Type: Grant
    Filed: May 24, 2012
    Date of Patent: November 4, 2014
    Assignee: CorMatrix Cardiovascular, Inc
    Inventors: Robert G. Matheny, Beecher C. Lewis
  • Patent number: 8871511
    Abstract: Methods for treating a cardiovascular disorder comprising concomitant administration of one or more extracellular matrix (ECM) based compositions directly to damaged or diseased cardiovascular tissue associated with the cardiovascular disorder, and provision of ventricular assistance. In a preferred embodiment, the ECM based compositions include an ECM material derived from a mammalian source.
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: October 28, 2014
    Assignee: CorMatrix Cardiovascular, Inc
    Inventors: Robert G Matheny, Anna Fallon
  • Patent number: 8845719
    Abstract: Extracellular matrix (ECM) material conduits are disclosed. Methods for regenerating atrioventricular valves to replace defective atrioventricular valves within a heart of a subject using the ECM material conduits are also disclosed. Methods of sterilizing and decellularizing an ECM material are also disclosed.
    Type: Grant
    Filed: May 24, 2012
    Date of Patent: September 30, 2014
    Assignee: CorMatrix Cardiovascular, Inc
    Inventor: Robert G. Matheny
  • Publication number: 20140249623
    Abstract: Anchored cardiovascular valves having a support member with at least one leaflet formed therein that is sized and configured to selectively restrict regurgitating blood through the valve, and at least one anchoring mechanism. In a preferred embodiment of the invention, the anchored valves have two anchoring mechanisms, i.e.
    Type: Application
    Filed: March 1, 2013
    Publication date: September 4, 2014
    Applicant: Cormatrix Cardiovascular, Inc.
    Inventor: Robert Matheny
  • Patent number: 8808363
    Abstract: A vascular prosthesis comprising a tubular shaped expandable ECM member and at least one anchoring mechanism. In one embodiment, the anchoring mechanism comprises proximal and distal single or dual-ring anchors. In one embodiment, the anchoring mechanism comprises a multiple-ring anchor. The anchors preferably comprise a biodegradable metal, such as magnesium. The anchors can also comprise a shape memory alloy, such as nitinol, and a cross-linked ECM material. In some embodiments, the ECM member includes a pharmacological agent.
    Type: Grant
    Filed: August 31, 2012
    Date of Patent: August 19, 2014
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventors: Michael David Perry, Robert G. Matheny
  • Patent number: 8795728
    Abstract: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
    Type: Grant
    Filed: January 2, 2013
    Date of Patent: August 5, 2014
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny
  • Patent number: 8785198
    Abstract: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: July 22, 2014
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny
  • Patent number: 8785197
    Abstract: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: July 22, 2014
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny
  • Patent number: 8778012
    Abstract: An extracellular matrix (ECM) construct having a biodegradable support scaffold that includes a plurality of biodegradable microneedles that are capable of piercing tissue and anchoring therein, and at least a first layer of first ECM material disposed on the top surface of the support scaffold.
    Type: Grant
    Filed: November 27, 2012
    Date of Patent: July 15, 2014
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G. Matheny
  • Patent number: D718862
    Type: Grant
    Filed: May 7, 2013
    Date of Patent: December 2, 2014
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny
  • Patent number: D718864
    Type: Grant
    Filed: May 7, 2013
    Date of Patent: December 2, 2014
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny
  • Patent number: D718865
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: December 2, 2014
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny
  • Patent number: D726914
    Type: Grant
    Filed: July 24, 2013
    Date of Patent: April 14, 2015
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert Matheny