Abstract: The present invention relates to a system and method configured to store and retrieve files and, specifically, to a system and method for encoding files, such as image files or video files, into compressed archive and then later retrieving the files from the compressed archive in response to user requests.

Abstract: Systems and methods for tracking EEG data and providing enhanced seizure detection and prediction are disclosed. The systems and methods use input sensors for receiving and collecting data from a plurality of EEG channels in association with a subject and processing said data to calculate and average Lyapunov exponents for a composite EEG data set. The systems and methods convert the average Lyapunov exponents into graphical representations that are displayed against a time axis. The graphical output adjusts in real-time according to the input data obtained from EEG channels. The systems and methods utilize pattern recognition to output alarms based upon input data and recommend diagnoses related to seizures.

Abstract: Systems and methods for detecting a traumatic brain injury (TBI). The system comprises a sensing arrangement and a control unit. The sensing arrangement collects eye movement data of a user. The control unit is in communication with the sensing arrangement and configured to compare the eye movement data to one or more baseline measurements of eye movement dynamics. The control unit is also configured to generate an alert indicating the presence or severity of the TBI for delivery to control unit administrator if the eye movement data diverges from one or more of the baseline measurements by a threshold amount.

Abstract: In accordance with some embodiments of the disclosed subject matter, systems, methods, and media for selectively presenting images captured by confocal laser endomicroscopy (CLE) are provided. In some embodiments, a method comprises: receiving images captured by a CLE device during brain surgery; providing the images to a convolution neural network (CNN) trained using at least a plurality of images of brain tissue captured by a CLE device and labeled diagnostic or non-diagnostic; receiving an indication, from the CNN, likelihoods that the images are diagnostic images; determining, based on the likelihoods, which of the images are diagnostic images; and in response to determining that an image is a diagnostic image, causing the image to be presented during the brain surgery.

Abstract: A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.

Abstract: An apparatus for surgical lighting is disclosed. The apparatus includes a light emitting element formed with a light source encapsulated within an outer layer. The outer layer includes a biocompatible material. A power supply is coupled to the light source. The apparatus includes an actuating mechanism that controls power from the power supply to the light source to emit light along a surgical area. The light emitting element provides enhanced illumination and other surgical advantages.

Abstract: Disclosed herein is a wheel shield apparatus that includes a pair of elongated parallel tube members in perpendicular engagement with a pair of short parallel tube members, at least one removable side of the wheel shield apparatus is operable to be temporarily opened or removed such that the wheel shield apparatus may be placed around a wheel of a neurosurgical microscope or some other type of heavy wheeled machinery and the removable side may be placed in a closed position such that the wheel shield surrounds the wheel. Each of the pair of elongated parallel tube members and/or each of the pair of short parallel tube members comprises a cavity configured to receive a ballast material to provide sufficient weight to ensure that the wheel shield apparatus contacts the floor such that cables along the floor are pushed out of the way by the wheel shield apparatus and prevented from being run over while the machinery is being transported.

Abstract: In accordance with some embodiments of the disclosed subject matter, systems, methods, and media for selectively presenting images captured by confocal laser endomicroscopy (CLE) are provided. In some embodiments, a method comprises: receiving images captured by a CLE device during brain surgery; providing the images to a convolution neural network (CNN) trained using at least a plurality of images of brain tissue captured by a CLE device and labeled diagnostic or non-diagnostic; receiving an indication, from the CNN, likelihoods that the images are diagnostic images; determining, based on the likelihoods, which of the images are diagnostic images; and in response to determining that an image is a diagnostic image, causing the image to be presented during the brain surgery.

Abstract: A toothbrush system configured to be coupled to an external suction source. The toothbrush system includes a shaft with a main body with a first end and a second end, and a bristle array and a suction port arranged at the second end. The bristle array and the suction port both extend away from the shaft so that an opening of the suction port is proximal to a distal end of the bristle array. The shaft also includes a stem arranged at the first end. The stem includes a passageway that extends through the main body to provide a fluid connection to the suction port, and is configured to be coupled to the external suction source. Also, the handle is removably coupled to the shaft and includes a drive system operably coupled to the bristle array to actuate motion of the bristle array.

Abstract: A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.

Abstract: Various embodiments of a system and method for the treatment of brain cancer using a subdurally-implanted alternating electric field generation apparatus are disclosed herein.

Abstract: Embodiments for a cerebrospinal fluid flow detector for detecting the flow of cerebrospinal fluid are disclosed. In some embodiments, the cerebrospinal fluid flow detector includes a casing with a rotatable wheel having a plurality of radially extending arms disposed therein. The rotatable wheel is in communication with a channel having a distal end in communication with an inlet port and a proximal end in communication with an outlet port such that the flow of cerebrospinal fluid through the channel causes the rotatable wheel to rotate. In some embodiments, each radially extending arm includes at least one radiopaque marker in which movement of the rotatable wheel caused by fluid flow through the channel allows an X-ray imaging apparatus to detect the difference in position of a respective radiopaque marker at multiple times caused by rotation of the rotatable wheel.

Abstract: The invention relates to a composition and use of the composition in the treatment of a disorder, for example, a neurological disease associated with retinoid signaling. The invention also includes the use of a retinoid encapsulated in nanoparticles. The retinoid encapsulated nanoparticles are adapted to increasing lifespan and conferring neuroprotective effects such as preserving motor units, reducing motor impairment, or reducing neuroinflammation in a subject.

Abstract: A medical device is disclosed including a needle guide. The needle guide includes abase, a guide member, and a handle arrangement. The base defines a base channel and the guide member includes a guide member channel in communication with one another and configured for receiving a flexible needle. The guide member includes a non-linear portion and is generally flexible to accommodate passage of a flexible needle through a corresponding portion of the guide member channel. The handle arrangement is configured to accommodate stabilization of the needle guide during deployment.

Abstract: Various embodiments of a pedicle screw assembly disclosed herein include a pedicle screw configured for engaging with bone tissue. The pedicle screw includes a body defining a plurality of channels through the body of the screw and in communication with a plurality of respective distal openings defined along the screw body. The pedicle screw assembly further includes an anchor defining a plurality of anchor members which are configured to be received at least partially through the plurality of channels and the plurality of respective distal openings to further engage the pedicle screw to the bone tissue.

Abstract: Systems, devices, and methods are provided for reducing a risk of unintentional falls in a subject that is at risk for falls. The device includes a sensor and a stimulator. The sensor is configured to be positioned adjacent a body portion of the user that changes orientation when the user sits and stands. The sensor is also configured to emit an activation signal when the user stands and to emit a deactivation signal when the user sits or lies down. The stimulator is in communication with the sensor and is configured to be positioned adjacent one of a calf and a lower back of the user. The stimulator is configured to vibrate at a frequency that stimulates proprioceptors of the user without inducing muscle contractions upon receipt of the activation signal from the sensor and to cease vibration upon receipt of the deactivation signal from the sensor.

Abstract: The present disclosure generally relates to a table-mounted retractor system for open-spine surgery. The table-mounted retractor system includes a frame, wherein the frame is situated lateral to the patient. The table-mounted retractor system further comprises a plurality of retractor hooks wherein each of the plurality of retractor hooks are in operative association with one of a plurality of tension lines, wherein each of the plurality of tension lines is engaged with the frame. Each one of the plurality of retractor hooks are operable to engage with the flesh of a patient as each of the tension lines pull the flesh back laterally towards the frame along each side of the patient.

Abstract: A system and method for bending a surgical rod using an automated bending system includes receiving an indication of a plurality of line segments defined on the rod and an indication of an angle measurement to be formed between at least two adjacent ones of the plurality of line segments. Bending parameters to perform on the rod to form the angle measurement between the at least two adjacent ones of the plurality of line segments are determined and operation of the automated bending system is controlled using the bending parameters to create an angle having the angle measurement between the at least two adjacent ones of the plurality of line segments.

Abstract: Systems and methods for detecting onset, presence, and progression of particular states, including intoxication, include observing eye movements of a subject and correlating the observed movements to known baseline neurophysiological indicators of intoxication. A detection system may record eye movement data from a user, compare the eye movement data to a data model comprising threshold eye movement data samples, and from the comparison make a determination whether or not intoxication or impairment is present. The detection system may alert the user to take corrective action if onset or presence of a dangerous condition is detected. The eye movements detected include saccadic and intersaccadic parameters such as intersaccadic drift velocity. Measurements may be collected in situ with a field testing device. An interactive application may be provided on a user device to provoke the desired eye movements during recording.

Abstract: The present disclosure generally relates to a sacroiliac joint coupler having a base plate and an angled plate for respective engagement with the sacrum and ilium are described herein. The sacroiliac joint coupler includes a bolt having a threaded distal end extending from a top face of the base plate and a fastener that couples the distal end of the bolt to the angled plate. In addition, the fastener may include a hinge or a locking ball.