Patents Assigned to Dr. Reddy's Laboratories Ltd.
  • Patent number: 9216943
    Abstract: The present application provide processes for the preparation of fingolimod and its pharmaceutically acceptable salts, process for the purification of fingolimod hydrochloride and process for the preparation of amorphous fingolimod hydrochloride.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: December 22, 2015
    Assignee: DR. REDDY'S LABORATORIES LTD.
    Inventors: Srinivas Katkam, Rajeswar Reddy Sagyam, Raghavendar Rao Morthala, Babu Ireni, Krishna Vinigari, Suresh Kumar Ramdoss, Srinivasulu Rangineni, Arjunkumar Tummala, Javed Iqbal, Srinivas Oruganti, Bhaskar Kandagatla
  • Patent number: 9211282
    Abstract: The invention provides a pharmaceutical composition for intranasal administration comprising a salt of sumatriptan or a physiologically acceptable solvate thereof, an alkyl glycoside or saccharide alkyl ester and optionally at least one pharmaceutically acceptable excipient, wherein the said composition provides Tmax value of less than 30 minutes upon said administration. Other aspects and embodiments are contemplated and described. The invention also provides a pharmaceutical composition for intranasal administration comprising a triptan, a pharmaceutically acceptable vehicle and a mucosal permeation enhancer, wherein upon said administration said composition provides a Tmax substantially equivalent to subcutaneous administration of said triptan. Other aspects and embodiments are contemplated and described.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: December 15, 2015
    Assignee: DR. REDDY'S LABORATORIES LTD.
    Inventors: Rajesh Gandhi, Sreekanth Manikonda, Arun Jana, Sameer Shrinivas Kunte
  • Patent number: 9199967
    Abstract: The present application relates to cycloalkylpyridin-2-amines derivates of formula (1) or stereoisomers thereof or pharmaceutically acceptable salts thereof. The present application also relates to the process for the preparation of compounds of formula (I). The present application further describes the compounds of formula (1) as cholesteryl ester-transfer protein (CETP) inhibitors. The present application further relates to pharmaceutical compositions comprising compounds of formula (1) or stereoisomers thereof or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: December 1, 2015
    Assignee: Dr. Reddy's Laboratories Ltd.
    Inventors: Anima Boruah, Shanavas Alikunju
  • Publication number: 20150258076
    Abstract: The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.
    Type: Application
    Filed: May 29, 2015
    Publication date: September 17, 2015
    Applicant: Dr. Reddy's Laboratories Ltd.
    Inventors: Pradip Kumar Sasmal, Shahadat Ahmed, Ashok Tehim, Vidyadhar Paradkar, Prasanna M. Dattatreya, Nanjegowda Jagadeesh Mavinahalli
  • Patent number: 9132144
    Abstract: The present invention provides a clear depot comprising at least one hydrophilic water-soluble pharmaceutically active agent selected from the group consisting of vancomycin, gentamicin, a pharmaceutically acceptable salt thereof and a mixture thereof, water, a phospholipid, an oil, optionally a pH adjusting agent, and a viscosity modifying agent selected from the group consisting of ethanol, isopropanol, and a mixture thereof, wherein the water present in the depot is no more than about 4 wt % relative to the total weight of the depot and the depot has a pH of between about 3 and about 6, method of making and administering same.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: September 15, 2015
    Assignee: Dr. Reddy's Laboratories Ltd.
    Inventors: Hailiang Chen, Andrew Xian Chen, Dushyanth Surakanti, Franklin Okumu
  • Publication number: 20150224121
    Abstract: Parenteral (injectable) celecoxib emulsions and nanoemulsions are disclosed as are their use to treat pain in patients so afflicted. The emulsions are generally oil in water emulsions often comprised of an oil phase including an oil and a lecithin wherein the mean droplet size of the discontinuous oil phase is about 200 nanometers or less.
    Type: Application
    Filed: February 11, 2015
    Publication date: August 13, 2015
    Applicant: Dr. Reddy's Laboratories Ltd.
    Inventors: Franklin Okumu, Jan-Jon Chu, Julie Ann Webb, Rafael Anthony Sabino, Andrew Xian Chen
  • Publication number: 20150164869
    Abstract: The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.
    Type: Application
    Filed: February 26, 2015
    Publication date: June 18, 2015
    Applicant: DR. REDDY'S LABORATORIES LTD.
    Inventors: Pradip Kumar Sasmal, Shahadat Ahmed, Ganesh Prabhu, Ashok Tehim, Vidyadhar Paradkar, Marahanakuli Prasanna Dattatreya, Nanjegowda Jagadeesh Mavinhalli
  • Patent number: 9045473
    Abstract: The present application relate to amorphous form of Apixaban useful in making pharmaceutically acceptable dosage forms, and to processes for their preparation.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: June 2, 2015
    Assignee: DR. REDDY'S LABORATORIES LTD.
    Inventors: Subba Reddy Peddi Reddy, Md Arshad Alam
  • Patent number: 9045479
    Abstract: The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.
    Type: Grant
    Filed: December 12, 2012
    Date of Patent: June 2, 2015
    Assignee: Dr. Reddy's Laboratories Ltd.
    Inventors: Pradip Kumar Sasmal, Shahadat Ahmed, Ganesh Prabhu, Ashok Tehim, Vidyadhar Paradkar, Marahanakuli Prasanna Dattatreya, Nanjegowda Jagadeesh Mavinhalli
  • Patent number: 9040558
    Abstract: The invention is directed to novel substituted benzylamino quinolines, compounds comprising substituted benzylamino quinolines, methods of making substituted benzylamino quinolines, the use of substituted benzylamino quinolines for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism, and the use of substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors.
    Type: Grant
    Filed: December 28, 2005
    Date of Patent: May 26, 2015
    Assignee: DR. REDDY'S LABORATORIES LTD.
    Inventors: Anima Baruah, Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti, Santanu Maitra, Christopher W. Alexander, Jennepalli Sreenu, Indu Dager, Shanavas Alikunju
  • Patent number: 9000007
    Abstract: The present application relates to a series of substituted pyra-zolopyridin-6-amines having the general formula (I), including their stereoisomers and/or their pharmaceutically acceptable salts. Wherein R, R1, R2, Ra, Raa, Rb and n are as defined herein. The present invention further relates to pharmaceutical compositions comprising compounds of formula (I). The compounds of this application are useful as CETP inhibitors for increasing HDL cholesterol and decreasing LDL cholesterol in a patient.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: April 7, 2015
    Assignee: Dr. Reddy's Laboratories Ltd.
    Inventors: Anima Boruah, Shanavas Alikunju
  • Patent number: 8969582
    Abstract: Processes for preparing febuxostat.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: March 3, 2015
    Assignee: Dr. Reddy's Laboratories Ltd.
    Inventors: Praveen Cherukupally, Sreenadha Charyulu Kandala, Vijay Kumar Adla, Chandra Sekhar Vempati
  • Publication number: 20150051580
    Abstract: An auto-injector device for administering a liquid pharmaceutical composition, in which an end-user can select between doses that the device is capable of delivering. The end-user choices that translate into the selected doses can be based on end-user perceived severity of symptoms, end-user weight and other such factors. In some embodiments the auto-injector is configured to administer the one chosen dose only. In other embodiments, the auto-injector can deliver second and subsequent doses up to full dose of the pharmaceutical composition disposed in the injector. The auto-injector can provide visual, audio, and tactile feedback, alone or in combination, to the user to indicate the dose selected, instructions for use, and when the dose has been administered.
    Type: Application
    Filed: August 18, 2014
    Publication date: February 19, 2015
    Applicant: Dr. Reddy's Laboratories, Ltd.
    Inventors: Adam M. Shain, Rajesh Kumar, Anil Namboodiripad
  • Publication number: 20150005280
    Abstract: The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.
    Type: Application
    Filed: December 12, 2012
    Publication date: January 1, 2015
    Applicant: DR. REDDY'S LABORATORIES LTD.
    Inventors: Pradip Kumar Sasmal, Shahadat Ahmed, Ganesh Prabhu, Ashok Tehim, Vidyadhar Paradkar, Marahanakuli Prasanna Dattatreya, Nanjegowda Jagadeesh Mavinahalli
  • Publication number: 20140371217
    Abstract: The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.
    Type: Application
    Filed: December 12, 2012
    Publication date: December 18, 2014
    Applicant: DR. REDDY'S LABORATORIES LTD.
    Inventors: Pradip Kumar Sasmal, Shahadat Ahmed, Ashok Tehim, Vidyadhar Pradkar, Prasanna M. Dattatreya, Nanjegowda Jagadeesh Mavinahalli
  • Publication number: 20140288072
    Abstract: The present application relates to a series of substituted pyra-zolopyridin-6-amines having the general formula (I), including their stereoisomers and/or their pharmaceutically acceptable salts. Wherein R, R1, R2, Ra, Raa, Rb and n are as defined herein. The present invention further relates to pharmaceutical compositions comprising compounds of formula (I). The compounds of this application are useful as CETP inhibitors for increasing HDL cholesterol and decreasing LDL cholesterol in a patient.
    Type: Application
    Filed: September 27, 2012
    Publication date: September 25, 2014
    Applicant: DR. REDDY'S LABORATORIES, LTD.
    Inventors: Anima Boruah, Shanavas Alikunju
  • Publication number: 20140256724
    Abstract: The present application relates to cycloalkylpyridin-2-amines derivates of formula (1) or stereoisomers thereof or pharmaceutically acceptable salts thereof. The present application also relates to the process for the preparation of compounds of formula (I). The present application further describes the compounds of formula (1) as cholesteryl ester-transfer protein (CETP) inhibitors. The present application further relates to pharmaceutical compositions comprising compounds of formula (1) or stereoisomers thereof or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: August 17, 2012
    Publication date: September 11, 2014
    Applicant: DR. REDDY'S LABORATORIES LTD.
    Inventors: Anima Boruah, Shanavas Alikunju
  • Publication number: 20140243412
    Abstract: Aspects of the present invention relate to improved process for preparation of (R)(?)-3-(carbamoylmethyl)-5-methylhexanoic acid (R-CMHA) of the formula (II) or its pharmaceutically acceptable salts in the presence of a lewis acid, process for preparation of pregabalin using R-CMHA of the formula (II) or its pharmaceutically acceptable salts prepared according to the present invention and process for preparation of pregabalin with low amount of undesired impurity.
    Type: Application
    Filed: February 27, 2014
    Publication date: August 28, 2014
    Applicant: Dr. Reddy's Laboratories Ltd.
    Inventors: Srinivas GANGULA, Uday Kumar NEELAM, Krishna VINIGARI, Vilas Hareshwar DAHANUKAR, Syam Kumar Unniaran KUNHIMON, Srinivas Reddy GADE
  • Publication number: 20140235895
    Abstract: The present application provide processes for the preparation of fingolimod and its pharmaceutically acceptable salts, process for the purification of fingolimod hydrochloride and process for the preparation of amorphous fingolimod hydrochloride.
    Type: Application
    Filed: April 27, 2012
    Publication date: August 21, 2014
    Applicant: DR. REDDY'S LABORATORIES LTD.
    Inventors: Srinivas Katkam, Rajeswar Reddy Sagyam, Raghavendar Rao Morthala, Babu Ireni, Krishna Vinigari, Suresh Kumar Ramdoss, Srinivasulu Rangineni, Arjunkumar Tummala, Javed Iqbal, Srinivas Oruganti, Bhaskar Kandagatla
  • Publication number: 20140187538
    Abstract: The present invention relates to amorphous lorcaserin hydrochloride; amorphous solid dispersion comprising lorcaserin hydrochloride and one or more pharmaceutically acceptable carries; processes for preparation thereof; pharmaceutical compositions comprising amorphous lorcaserin hydrochloride and one or more pharmaceutically acceptable carries.
    Type: Application
    Filed: December 26, 2013
    Publication date: July 3, 2014
    Applicant: DR. REDDY'S LABORATORIES LTD.
    Inventors: Rajesham Boge, Arjun Kumar Tummala, Vishweshwar Peddy, Srinivasulu Rangineni, Vilas Hareshwar Dahanukar, Bandichhor Rakeshwar, Areveli Srinivas, Macharla Prabhakar, Varanasi Ganesh