Patents Assigned to DSM
  • Publication number: 20090258954
    Abstract: (Modified) rice endosperm protein is used as novel protective hydrocolloid for active ingredients, especially fat-soluble active ingredients and/or colorants. Included are compositions comprising (modified) rice endosperm protein and at least one active ingredient and to their manufacture, as well as to the (modified) rice endosperm protein itself and its manufacture. These compositions are used for the enrichment, fortification and/or coloration of food, beverages, animal feed, personal care or pharmaceutical compositions, and to food, beverages, animal feed, personal care and pharmaceutical compositions containing such a (modified) rice endosperm protein and such a composition, respectively.
    Type: Application
    Filed: December 8, 2006
    Publication date: October 15, 2009
    Applicant: DSM ASSETS B.V.
    Inventors: Markus Beck, Navagnana S. Hettiarachchy, Bruno H. Leuenberger, IIankovan Paraman, Christian Schaefer, Gerhard Wagner
  • Patent number: 7601245
    Abstract: The invention relates to a process for reducing the aldehyde concentration in a mixture comprising cyclohexanone and one or more aldehydes, said process comprising distilling said mixture in a distillation column in the presence of an alkaline compound, wherein in the bottom of the distillation column substantially no water is present.
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: October 13, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Arno H Benneker, Augustinus P H Schouteten, Larry W Wyatt
  • Patent number: 7601877
    Abstract: A process for the preparation of ubihydroquinones and ubiquinones by condensation of a prenol or isoprenol with a hydroquinone or derivative thereof in the presence of 0.005-1.0 mol % of a catalyst which is a Broensted-acid, a Lewis-acid from the group consisting of a derivative of Bi or In or an element of group 3 of the periodic table of the elements, a heteropolyacid, an NH— or a CH-acidic compound, and optionally oxidizing the ubihydroquinone obtained.
    Type: Grant
    Filed: August 2, 2006
    Date of Patent: October 13, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Fabrice Aquino, Werner Bonrath, Patrick Bohrer, Max Hugentobler, Thomas Netscher, Alexander Radspieler
  • Publication number: 20090252719
    Abstract: Laminitis is defined as an inflammation of the sensitive laminae of the hoof, especially in horses. It has been surprisingly found that fructanases such as 2,1-?-D-fructan hydrolase are highly effective as therapeutic and prophylactic agents against laminitis in horses. The fructanases may be used as enzyme compositions in horse feed, as additives for horse feed or as oral preparations for the therapy and prophylaxis of laminitis. Because of its effectiveness in hydrolyzing fructans, which seem to play an important role in the aetiology of laminitis, the administration of fructanases in combination with an increased intake of fructans or with an increased availability of fructans is particularly advantageous.
    Type: Application
    Filed: October 18, 2006
    Publication date: October 8, 2009
    Applicant: DSM IP ASSETS B.V.
    Inventors: Petra Philipps, Jeppe Wegener Tams
  • Patent number: 7598066
    Abstract: Disclosed is an isolated DNA encoding vitamin B6 phosphate phosphatase selected from the group consisting of: (a) a DNA sequence represented in SEQ ID NO:9; (b) a DNA sequence which encodes a polypeptide having vitamin B6 phosphate phosphatase activity and hybridizes under standard conditions to the DNA sequence defined in (a) or a fragment of thereof; (c) a DNA sequence which encodes a polypeptide having vitamin B6 phosphate phosphatase activity, wherein said polypeptide is at least 70% identical to the amino acid sequence represented in SEQ ID NO:10; (d) a DNA sequence which encodes a polypeptide having vitamin B6 phosphate phosphatase activity and is at least 70% identical to the DNA sequence represented in SEQ ID NO:9; (e) a degenerate DNA sequence of any one of (a) to (c).
    Type: Grant
    Filed: September 23, 2003
    Date of Patent: October 6, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Tatsuo Hoshino, Yoshie Nagahashi, Masaaki Tazoe
  • Patent number: 7592166
    Abstract: Disclosed is an isolated DNA comprising a nucleotide sequence coding for an enzyme having enone reductase activity wherein the enzyme is characterized by the following physico-chemical properties: (a) molecular mass: 61,300±5,000 Da (estimated using gel filtration, consisting of one subunit); (b) co-factor: NADPH and NADH; (c) substrate specificity: active on ?,?-unsaturated ketons; (d) optimum temperature: 55-60° C. at pH 7.4; and (e) optimum pH: pH 4.5-8.5.
    Type: Grant
    Filed: September 19, 2003
    Date of Patent: September 22, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Michihiko Kataoka, Sakayu Shimizu
  • Patent number: 7592841
    Abstract: Circuits using four terminal junction field effect transistors (JFETs) are disclosed. Such circuits can include various static and dynamic logic circuits, flip-flops, multiplexer, tri-state driver, phase detector, logic having variable speeds of operation, and/or analog circuit with such four terminal JFETs operating in a linear or nonlinear mode.
    Type: Grant
    Filed: June 13, 2006
    Date of Patent: September 22, 2009
    Assignee: DSM Solutions, Inc.
    Inventor: Ashok Kumar Kapoor
  • Publication number: 20090232936
    Abstract: The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel lipolytic enzyme from Aspergillus niger The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel lipolytic enzyme as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a lipolytic enzyme according to the invention is genetically modified to enhance its activity and/or level of expression.
    Type: Application
    Filed: May 6, 2009
    Publication date: September 17, 2009
    Applicant: DSM IP ASSETS B.V.
    Inventors: Richard Albang, Andreas Fritz, Oliver Heinrich, Hilmar Ilgenfritz, Dieter Maier, Christian Wagner, Ulrike Folkers, Beatrix Gerhard, Fabio Spreafico, Lex De Boer, Roelf Bernhard Meima
  • Patent number: 7589198
    Abstract: Process for the preparation of melamine, comprising a first mixing step in which at least two melamine-containing flows, originating from at least two different processes for the preparation of melamine, are brought into contact with each other, with a mixture being formed. In one embodiment, at least one melamine-containing flow contains melamine from a low-pressure gas-phase process for the preparation of melamine and at least one melamine-containing flow contains melamine from a high-pressure liquid-phase process for the preparation of melamine.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: September 15, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Tjay Tjien Tjioe, Eric Grolman, Reinier Franciscus Petrus Grimbergen, Michal Kuczynski
  • Patent number: 7588925
    Abstract: The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel phospholipase isolated from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel phospholipase as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a phospholipase according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
    Type: Grant
    Filed: October 10, 2006
    Date of Patent: September 15, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Kaj Albermann, Wolfram Kemmner, Dieter Maier, Fabio Spreafico, Alexander Stock, Christian Wagner, Lex De Boer, Roelf Bernhard Meima
  • Patent number: 7589136
    Abstract: The invention relates to a process for the preparation of a polymer composition, the process comprising a step of contacting a polymer that comprises carboxyl groups with a cyclic imino ether compound characterized in that the cyclic imino ether compound is a phenylene oxazine according to formula (I), in which formula R=an oxazine group according to formula (II) n=0, 1, 2, 3, 4 or 5 and that the polymer is contacted with said oxazine in an extruder at a temperature above 100° C.
    Type: Grant
    Filed: September 17, 2004
    Date of Patent: September 15, 2009
    Assignee: DSM IP Assets B.V.
    Inventor: Jacobus A. Loontjens
  • Patent number: 7588913
    Abstract: The present invention describes a process for preparing cephradine, said process comprising reacting 7-aminodesacetoxy cephalosporanic acid (7-ADCA) with D-dihydrophenylglycine in activated form (DHa) in the presence of an enzyme in a reaction mixture to form cephradine, resulting in a conversion of 7-ADCA into cephradine of at least 70%, wherein the concentration D-dihydrophenylglycine (DH) in the reaction mixture is below 2 wt.%, wherein the conversion of 7-ADCA into cephradine & equals; (nCEF/n7-ADCA)*100%, wherein nCEF=quantity of cephradine formed (in mole); and n7-ADCA=total quantity of 7-ADCA added to reaction mixture (in mole).
    Type: Grant
    Filed: July 1, 2004
    Date of Patent: September 15, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Dennis Heemskerk, Anja Gerarda Margaretha Hogenboom, Carlos Enrique Lenhardt, Harold Monro Moody, Theodorus Johannes Godfried Maria Van Dooren
  • Publication number: 20090227678
    Abstract: The present invention relates to a process for obtaining lipid from a composition comprising cells and water, said process comprising contacting the composition with a desiccant, and recovering the lipid from the cells. The invention also relates to a lipid obtainable by this process. The process according to then invention enables lipid of high quality to be obtained with a high yield, and does not require a heating step.
    Type: Application
    Filed: June 19, 2006
    Publication date: September 10, 2009
    Applicants: DSM IP Assets B.V., Martek Biosciences Corp.
    Inventors: Hendrik Louis Bijl, Daniel Verkoeijen, Heinz Niggli
  • Patent number: 7582088
    Abstract: Bone fixing devices include (I) a surgical cable having a first end and a second end and (II) at least a first fixing plate and a second fixing plate. The first and second fixing plates are respectively provided with first and second central holes and first and second rings surrounding the first and second holes. The circumference of each fixing plate defines an outer edge of its respective ring and an inner edge of the ring being adjacent to the hole it surrounds. The first fixing plate is in a stacked position on top of the second plate so as to define a gap therebetween with the plates and the holes at least partly overlapping each other. The cable ends follow a continuous trajectory running around and between the plates and through the holes in such way that by drawing the cable ends the cable is tensioned around the bone parts so as to and fixate the same.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: September 1, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Roelof Marissen, Karel Jozef Wetzels
  • Patent number: 7582576
    Abstract: The invention relates to a soft and flexible surgical soft tissue mesh comprising polyethylene yarns, wherein the polyethylene yarns have a tensile strength of more than 1.0 Gpa and consist of a polyethylene with a relative viscosity of more than 5 dl/g. A further aspect of the invention is a method of producing a soft and flexible surgical soft tissue mesh comprising polyethylene yarns, wherein yarns are applied that comprise filaments made by: a) spinning at least one filament from a solution of polyethylene with a relative viscosity of more than 5 dl/g in a solvent; b) cooling the filament obtained to form a gel filament; c) removing at least partly the solvent from the gel filament; and d) drawing the filament in at least one drawing step before, during or after removing solvent.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: September 1, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Carina Sacha Snijder, Leonard Josef Arnold Nielaba
  • Patent number: 7582674
    Abstract: Compositions including, as the active ingredients, resveratrol, a derivative, metabolite or analogue thereof, and at least one additional component selected from epigallocatechin gallate (EGCG), genestein, vitamin E, polyunsaturated fatty acids, gamma-linolenic acid and vitamin K are disclosed. Also disclosed, are methods of making such compositions including admixing resveratrol, a derivative, metabolite or analogue thereof, and at least one additional component selected from EGCG, genestein, vitamin E, polyunsaturated fatty acids, gamma-linolenic acid and vitamin K are disclosed. Methods for the treatment or prevention of inflammatory diseases including administering to a subject in need of such treatment resveratrol, a derivative, metabolite or analogue thereof, in combination with at least one additional component selected from epigallocatechin gallate (EGCG), genestein, vitamin E, polyunsaturated fatty acids, gamma-linolenic acid and vitamin K are also disclosed.
    Type: Grant
    Filed: May 18, 2004
    Date of Patent: September 1, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Daniel Raederstorff, Joseph Schwager, Volker Spitzer, Peter Weber
  • Publication number: 20090211218
    Abstract: The invention relates to a method of increasing the molecular mass of a polycondensate in solution, wherein polycondensate is reacted with at least one chain extender out of the group consisting of bislactams, cyclic amino ethers, siloxanes and thiols. The invention further relates to a high molecular mass polycondensate in solution, wherein the polycondensate has an intrinsic viscosity as measured in hexafluoroisopropanol of at least 0.9 dl/g and a molecular mass distribution (Mw/Mn) of less than (2). The invention further relates to a process for producing a filament or film of a polycondensate comprising forming a solution of polycondensate by the method according to the invention, extruding the solution through a spinneret or a slot die, through air and into a cooling bath to form a gel filament or film, optionally removing residual solvent from the filament or film and drawing the filament or film at least (15), preferably at least (25) times.
    Type: Application
    Filed: June 13, 2006
    Publication date: August 27, 2009
    Applicant: DSM IP ASSETS B.V.
    Inventors: Jacobus Antonius JA Loontjens, Harm H. van der Werff, Marko M. Dorschu, Theo Joseph TJ Cuypers
  • Publication number: 20090214661
    Abstract: A process for the production of cross-linked beadlets containing one or more active ingredients selected from the group of a fat-soluble vitamin active material, a carotenoid and a polyunsaturated fatty acid is provided. The process comprises treating a dry particulate form at a temperature in the range of from 90° C. to 140° C. for a time period of from 30 seconds to 30 minutes or from 1 minute to 10 minutes or from 3 minutes to 7 minutes.
    Type: Application
    Filed: April 1, 2009
    Publication date: August 27, 2009
    Applicant: DSM IP ASSETS B.V.
    Inventors: Sylvain DIGUET, Toresten Huber, Johann Ulm
  • Publication number: 20090214647
    Abstract: The present invention describes a process for the manufacture of a solid composition comprising a microorganism, which process comprises a first step of blending and/or compacting the microorganism with a salt of a medium or long-chain fatty acid to prepare a powderous mixture or compacted granulate, and a second step of providing said powderous mixture or compacted granulate with a coating. The microorganisms are preferably probiotics. The invention also relates to the solid composition obtained by said process and to its use in food.
    Type: Application
    Filed: May 18, 2006
    Publication date: August 27, 2009
    Applicant: DSM IP ASSETS B.V.
    Inventors: Chyi-Cheng Chen, Bruno H. Leuenberger, Loni Schweikert, Ernst Zedi
  • Publication number: 20090215135
    Abstract: The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also features polynucleotides comprising the full-length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. The present invention also relates to the use of said polynucleotides and polypeptides as biotechnological tools in the production of Vitamin C from microorganisms, whereby a modification of said polynucleotides and/or encoded polypeptides has a direct or indirect impact on yield, production, and/or efficiency of production of the fermentation product in said microorganism. Also included are methods/processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms.
    Type: Application
    Filed: February 10, 2006
    Publication date: August 27, 2009
    Applicant: DSM IP ASSETS B.V.
    Inventors: Marie-Gabrielle Beuzelin-Ollivier, Bastian Chevreux, Manuela Dalluege, Markus G. Goese, Connie Lee, Anja Meury, Nigel J. Mouncey, Masako Shinjoh