Patents Assigned to Edwards Lifesciences PVT
  • Patent number: 10052203
    Abstract: A prosthetic heart valve comprises a radially crimpable and radially expandable, net-like, annular support frame and a valve assembly disposed therein, the valve assembly comprising a conduit tapering from an inlet towards an outlet thereof. Some embodiments or the support frame comprise a proximal portion and a distal portion, a diameter of the proximal portion smaller than a diameter of the distal portion. The proximal portion is dimensioned for deployment in an annulus of a native aortic valve and a distal portion for deployment in an ascending aorta. Some embodiments of the conduit comprise a support construction with a three-cusp, crown-shaped cut line, the support construction sutured to the support frame around a bottom portion thereof and around the cut line. A method for using the prosthetic heart valve to replace a defective native aortic valve uses a minimally invasive procedure.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: August 21, 2018
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Publication number: 20180200054
    Abstract: A system for replacing a deficient native aortic valve includes an implantable prosthetic valve having a self-expandable frame and a valve assembly formed with three valve leaflets. The self-expandable frame includes three angularly spaced longitudinal bars of fixed length defining respective slots and a plurality of web-like constructions extending between and connected to the longitudinal bars. The valve assembly includes commissures extending outwardly through the slots where they are supported on the outside of the frame. Each leaflet includes an inlet end portion secured to the inside of the frame with stitching extending through the leaflet and around adjacent frame portions. The system also includes a restriction tube adapted for insertion into a patient's body. The prosthetic valve is capable of being crimped for insertion into the restriction tube and capable of self-expansion upon release from the restriction tube for deployment in the deficient native aortic valve.
    Type: Application
    Filed: March 13, 2018
    Publication date: July 19, 2018
    Applicant: Edwards Lifesciences PVT, Inc.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Patent number: 9937039
    Abstract: A system for replacing a deficient native aortic valve includes an implantable prosthetic valve having a self-expandable frame and a valve assembly formed with three valve leaflets. The self-expandable frame includes a plurality of support beams, each support beam having a plurality of preformed bores for allowing the valve assembly to be anchored to the frame at least in part by stitching that extends through the leaflets and through the preformed bores of the support beams. The system also includes a restriction tube adapted for insertion into a patient's body. The prosthetic valve is capable of being crimped for insertion into the restriction tube and capable of self-expansion upon release from the restriction tube for deployment in the deficient native aortic valve.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: April 10, 2018
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Publication number: 20170224481
    Abstract: A system for replacing a deficient native aortic valve includes an implantable prosthetic valve having a self-expandable frame and a valve assembly formed with three valve leaflets. The self-expandable frame includes a plurality of support beams, each support beam having a plurality of preformed bores for allowing the valve assembly to be anchored to the frame at least in part by stitching that extends through the leaflets and through the preformed bores of the support beams. The system also includes a restriction tube adapted for insertion into a patient's body. The prosthetic valve is capable of being crimped for insertion into the restriction tube and capable of self-expansion upon release from the restriction tube for deployment in the deficient native aortic valve.
    Type: Application
    Filed: April 24, 2017
    Publication date: August 10, 2017
    Applicant: Edwards Lifesciences PVT, Inc.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Publication number: 20170189183
    Abstract: A prosthetic heart valve comprises a radially crimpable and radially expandable, net-like, annular support frame and a valve assembly disposed therein, the valve assembly comprising a conduit tapering from an inlet towards an outlet thereof. Some embodiments or the support frame comprise a proximal portion and a distal portion, a diameter of the proximal portion smaller than a diameter of the distal portion. The proximal portion is dimensioned for deployment in an annulus of a native aortic valve and a distal portion for deployment in an ascending aorta. Some embodiments of the conduit comprise a support construction with a three-cusp, crown-shaped cut line, the support construction sutured to the support frame around a bottom portion thereof and around the cut line. A method for using the prosthetic heart valve to replace a defective native aortic valve uses a minimally invasive procedure.
    Type: Application
    Filed: March 23, 2017
    Publication date: July 6, 2017
    Applicant: Edwards Lifesciences PVT, Inc.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Patent number: 9629714
    Abstract: A prosthetic valve is provided for implantation in a stenosed aortic valve. The prosthetic valve includes a radially collapsible frame configured for advancement through a patient's vasculature using a catheterization technique. A collapsible valvular structure is sewn to the frame for permitting blood to flow in only one direction. An internal cover extends along an internal surface of the frame. The internal cover forms a tubular sleeve positioned between a lower extremity of the frame and the valvular structure. The internal cover prevents the passage of blood through spaces between bars of the frame. An upper end of the internal cover is sutured to the valvular structure. The internal cover is preferably made of pericardium.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: April 25, 2017
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventors: Brice Letac, Alain Cribier
  • Patent number: 9629717
    Abstract: A prosthetic heart valve assembly suitable for implantation in body ducts via a catheter. The prosthetic heart valve assembly includes a collapsible and expandable tubular frame having an inlet end and an outlet end. The frame is preferably made from a self-expanding material. Three pericardial leaflets form a tricuspid valve having a top portion, a middle portion, and a bottom portion. Three longitudinal support members are positioned along an internal surface of the frame, desirably proximate to the outlet end. Each support member includes a pair of longitudinal surfaces that extends radially inwardly. End portions of adjacent valve leaflets extend through a gap between the pairs of longitudinal surfaces of each support member. The end portions are sutured to the longitudinal support members. The bottom portion of the tricuspid valve is sutured to the inlet end of the frame.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: April 25, 2017
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Patent number: 9486312
    Abstract: A prosthetic valve for implantation in a stenosed aortic valve. The prosthetic valve includes a metallic frame formed with intersecting bars having diameters in the range of 0.1 to 0.6 mm. The frame is radially collapsible for advancement into a native aortic valve using a catheterization technique. The frame is radially expandable for embedding the frame within the native aortic valve. The frame has sufficient radial strength to resist the recoil forces of the native aortic valve after implantation. The prosthetic valve includes a collapsible valvular structure made with pericardium. The prosthetic valve also includes an internal cover which forms a substantially impermeable tubular sleeve. The internal cover preferably extends between a lower extremity of the frame and the valvular structure. The internal cover is preferably sutured to the valvular structure. The valvular structure and internal cover are sutured to the bars of the frame.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: November 8, 2016
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventors: Brice Letac, Alain Cribier
  • Patent number: 9339383
    Abstract: A prosthetic heart valve comprises a radially crimpable and radially expandable, net-like, annular support frame and a valve assembly disposed therein, the valve assembly comprising a conduit tapering from an inlet towards an outlet thereof. Some embodiments or the support frame comprise a proximal portion and a distal portion, a diameter of the proximal portion smaller than a diameter of the distal portion. The proximal portion is dimensioned for deployment in an annulus of a native aortic valve and a distal portion for deployment in an ascending aorta. Some embodiments of the conduit comprise a support construction with a three-cusp, crown-shaped cut line, the support construction sutured to the support frame around a bottom portion thereof and around the cut line. A method for using the prosthetic heart valve to replace a defective native aortic valve uses a minimally invasive procedure.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: May 17, 2016
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Publication number: 20160038284
    Abstract: A prosthetic heart valve comprises a radially crimpable and radially expandable, net-like, annular support frame and a valve assembly disposed therein, the valve assembly comprising a conduit tapering from an inlet towards an outlet thereof. Some embodiments or the support frame comprise a proximal portion and a distal portion, a diameter of the proximal portion smaller than a diameter of the distal portion. The proximal portion is dimensioned for deployment in an annulus of a native aortic valve and a distal portion for deployment in an ascending aorta. Some embodiments of the conduit comprise a support construction with a three-cusp, crown-shaped cut line, the support construction sutured to the support frame around a bottom portion thereof and around the cut line. A method for using the prosthetic heart valve to replace a defective native aortic valve uses a minimally invasive procedure.
    Type: Application
    Filed: October 20, 2015
    Publication date: February 11, 2016
    Applicant: Edwards Lifesciences PVT, Inc.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Publication number: 20160030168
    Abstract: A prosthetic heart valve comprises a radially crimpable and radially expandable, net-like, annular support frame and a valve assembly disposed therein, the valve assembly comprising a conduit tapering from an inlet towards an outlet thereof. Some embodiments or the support frame comprise a proximal portion and a distal portion, a diameter of the proximal portion smaller than a diameter of the distal portion. The proximal portion is dimensioned for deployment in an annulus of a native aortic valve and a distal portion for deployment in an ascending aorta. Some embodiments of the conduit comprise a support construction with a three-cusp, crown-shaped cut line, the support construction sutured to the support frame around a bottom portion thereof and around the cut line. A method for using the prosthetic heart valve to replace a defective native aortic valve uses a minimally invasive procedure.
    Type: Application
    Filed: October 9, 2015
    Publication date: February 4, 2016
    Applicant: Edwards Lifesciences PVT, Inc.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Publication number: 20150320552
    Abstract: A prosthetic valve is provided for implantation in a stenosed aortic valve. The prosthetic valve includes a radially collapsible frame configured for advancement through a patient's vasculature using a catheterization technique. A collapsible valvular structure is sewn to the frame for permitting blood to flow in only one direction. An internal cover extends along an internal surface of the frame. The internal cover forms a tubular sleeve positioned between a lower extremity of the frame and the valvular structure. The internal cover prevents the passage of blood through spaces between bars of the frame. An upper end of the internal cover is sutured to the valvular structure. The internal cover is preferably made of pericardium.
    Type: Application
    Filed: July 21, 2015
    Publication date: November 12, 2015
    Applicant: Edwards Lifesciences PVT, Inc.
    Inventors: Brice Letac, Alain Cribier
  • Patent number: 9168133
    Abstract: A prosthetic heart valve comprises a radially crimpable and radially expandable, net-like, annular support frame and a valve assembly disposed therein, the valve assembly comprising a conduit tapering from an inlet towards an outlet thereof. Some embodiments or the support frame comprise a proximal portion and a distal portion, a diameter of the proximal portion smaller than a diameter of the distal portion. The proximal portion is dimensioned for deployment in an annulus of a native aortic valve and a distal portion for deployment in an ascending aorta. Some embodiments of the conduit comprise a support construction with a three-cusp, crown-shaped cut line, the support construction sutured to the support frame around a bottom portion thereof and around the cut line. A method for using the prosthetic heart valve to replace a defective native aortic valve uses a minimally invasive procedure.
    Type: Grant
    Filed: May 19, 2015
    Date of Patent: October 27, 2015
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Patent number: 9132006
    Abstract: A prosthetic heart valve comprises a radially crimpable and radially expandable, net-like, annular support frame and a valve assembly disposed therein, the valve assembly comprising a conduit tapering from an inlet towards an outlet thereof. Some embodiments or the support frame comprise a proximal portion and a distal portion, a diameter of the proximal portion smaller than a diameter of the distal portion. The proximal portion is dimensioned for deployment in an annulus of a native aortic valve and a distal portion for deployment in an ascending aorta. Some embodiments of the conduit comprise a support construction with a three-cusp, crown-shaped cut line, the support construction sutured to the support frame around a bottom portion thereof and around the cut line. A method for using the prosthetic heart valve to replace a defective native aortic valve uses a minimally invasive procedure.
    Type: Grant
    Filed: January 20, 2014
    Date of Patent: September 15, 2015
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Publication number: 20150250591
    Abstract: A prosthetic heart valve comprises a radially crimpable and radially expandable, net-like, annular support frame and a valve assembly disposed therein, the valve assembly comprising a conduit tapering from an inlet towards an outlet thereof. Some embodiments or the support frame comprise a proximal portion and a distal portion, a diameter of the proximal portion smaller than a diameter of the distal portion. The proximal portion is dimensioned for deployment in an annulus of a native aortic valve and a distal portion for deployment in an ascending aorta. Some embodiments of the conduit comprise a support construction with a three-cusp, crown-shaped cut line, the support construction sutured to the support frame around a bottom portion thereof and around the cut line. A method for using the prosthetic heart valve to replace a defective native aortic valve uses a minimally invasive procedure.
    Type: Application
    Filed: May 19, 2015
    Publication date: September 10, 2015
    Applicant: EDWARDS LIFESCIENCES PVT, INC.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Patent number: 9095432
    Abstract: A prosthetic valve is provided for implantation in a stenosed aortic valve. The prosthetic valve includes a radially collapsible frame configured for advancement through a patient's vasculature using a catheterization technique. A collapsible valvular structure is sewn to the frame for permitting blood to flow in only one direction. An internal cover extends along an internal surface of the frame. The internal cover forms a tubular sleeve positioned between a lower extremity of the frame and the valvular structure. The internal cover prevents the passage of blood through spaces between bars of the frame. An upper end of the internal cover is sutured to the valvular structure. The internal cover is preferably made of pericardium.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: August 4, 2015
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventor: Alain Cribier
  • Publication number: 20140135911
    Abstract: A prosthetic heart valve comprises a radially crimpable and radially expandable, net-like, annular support frame and a valve assembly disposed therein, the valve assembly comprising a conduit tapering from an inlet towards an outlet thereof. Some embodiments or the support frame comprise a proximal portion and a distal portion, a diameter of the proximal portion smaller than a diameter of the distal portion. The proximal portion is dimensioned for deployment in an annulus of a native aortic valve and a distal portion for deployment in an ascending aorta. Some embodiments of the conduit comprise a support construction with a three-cusp, crown-shaped cut line, the support construction sutured to the support frame around a bottom portion thereof and around the cut line. A method for using the prosthetic heart valve to replace a defective native aortic valve uses a minimally invasive procedure.
    Type: Application
    Filed: January 20, 2014
    Publication date: May 15, 2014
    Applicant: EDWARDS LIFESCIENCES PVT, INC.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Publication number: 20140081392
    Abstract: A prosthetic valve is provided for implantation in a stenosed aortic valve. The prosthetic valve includes a radially collapsible frame configured for advancement through a patient's vasculature using a catheterization technique. A collapsible valvular structure is sewn to the frame for permitting blood to flow in only one direction. An internal cover extends along an internal surface of the frame. The internal cover forms a tubular sleeve positioned between a lower extremity of the frame and the valvular structure. The internal cover prevents the passage of blood through spaces between bars of the frame. An upper end of the internal cover is sutured to the valvular structure. The internal cover is preferably made of pericardium.
    Type: Application
    Filed: November 25, 2013
    Publication date: March 20, 2014
    Applicant: Edwards Lifesciences PVT, Inc.
    Inventors: Brice Letac, Alain Cribier
  • Patent number: 8632586
    Abstract: A method of replacing a deficient native aortic valve with a self-expandable prosthetic valve is disclosed. The method involves advancing a self-expandable prosthetic valve through a tapered tube for crimping the prosthetic valve into a crimped diameter. The prosthetic valve is then advanced into a restriction tube for maintaining the prosthetic valve in the crimped diameter. The prosthetic valve is then advanced into a body and is positioned within the deficient native aortic valve. The prosthetic valve is then released from the restriction tube such that the prosthetic valve self-expands to an expanded diameter for anchoring within the deficient native aortic valve. The prosthetic valve comprises an expandable tubular support frame and a valve assembly positioned within the support frame. The valve assembly is formed with pericardial tissue and has three leaflets for providing blockage to a reverse flow of blood.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: January 21, 2014
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventors: Benjamin Spenser, Netanel Benichou, Assaf Bash, Avraham Zakai
  • Patent number: 8591575
    Abstract: A method for treating a stenotic native aortic valve in a human heart is provided. The method comprises dilating the stenotic native aortic valve using a dilatation catheter and then deploying a prosthetic heart valve within the dilated stenotic native aortic valve. The prosthetic heart valve comprises a collapsible and expandable metallic stent and a valvular structure formed of a synthetic biocompatible material. The valvular structure is positioned substantially between the inlet and outlet ends of the stent for preventing the flow of blood in one direction. The prosthetic heart valve may further comprise an internal sleeve for creating a seal along at least a portion of the stent wall.
    Type: Grant
    Filed: March 28, 2007
    Date of Patent: November 26, 2013
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventor: Alain Cribier