Patents Assigned to Eidgenossische Technische Hochschule (ETH)
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Patent number: 10564230Abstract: A magnetic field probe, particularly for magnetic resonance applications, comprises: —a detector liquid that exhibits a nuclear magnetic resonance (NMR) line characterized by a chemical shift ?; —an electrically conductive structure surrounding the detector liquid for receiving therefrom a magnetic resonance signal; and —a container containing the detector liquid; —the detector liquid containing paramagnetic dopant means dissolved therein; —said NMR transition having an observable resonance frequency ? when the field probe is placed in an external magnetic field; and has orientation means for orienting the field probe in relation to a reference direction of said external magnetic field.Type: GrantFiled: May 16, 2016Date of Patent: February 18, 2020Assignees: Eidgenossische Technische Hochschule (ETH), Universitat ZurichInventors: Simon Gross, Christoph Barmet
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Patent number: 10379190Abstract: A method of determining an actual gradient impulse response function during execution of a magnetic resonance (MR) imaging or spectroscopy sequence, wherein a main magnetic field is generated in a sample region of an MR apparatus by means of a main magnet and wherein superimposed time dependent gradient fields and radiofrequency fields in a first RF band are generated in the sample region according to a first MR sequence for forming images or spectra, the gradient fields being generated by gradient forming means of the MR apparatus operated according to a gradient forming sequence part of said first MR sequence, the MR apparatus further comprising at least one magnetic field probe.Type: GrantFiled: May 12, 2016Date of Patent: August 13, 2019Assignee: Eidgenossische Technische Hochschule (ETH) ETH ZentrumInventors: Bertram Wilm, Christoph Barmet, Klaas P. Prussmann
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Publication number: 20180321335Abstract: A magnetic field probe, particularly for magnetic resonance applications, comprises: —a detector liquid that exhibits a nuclear magnetic resonance (NMR) line characterized by a chemical shift ?; —an electrically conductive structure surrounding the detector liquid for receiving therefrom a magnetic resonance signal; and —a container containing the detector liquid; —the detector liquid containing paramagnetic dopant means dissolved therein; —said NMR transition having an observable resonance frequency ? when the field probe is placed in an external magnetic field; and has orientation means for orienting the field probe in relation to a reference direction of said external magnetic field.Type: ApplicationFiled: May 16, 2016Publication date: November 8, 2018Applicants: Eidgenossische Technische Hochschule (ETH), Universitat ZurichInventors: Simon Gross, Christoph Barmet
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Publication number: 20180292480Abstract: A magnetic resonance (MR) system comprises a main magnetic field and an RF power amplifier for generating an RF field in a first RF band, the arrangement further comprising at least one magnetic field probe (2), said magnetic field probe comprising a MR active probe substance, means for pulsed MR excitation of said probe substance (4) in a second RF band and means for receiving a probe MR signal in the second RF band generated by said probe substance. In order to improve performance of the system, the latter comprises means for recording the output signal of the RF power amplifier in said second RF band, and means for subtracting from said probe MR signal an interfering signal contribution contained in said recorded RF amplifier output signal.Type: ApplicationFiled: May 11, 2016Publication date: October 11, 2018Applicants: Eidgenossische Technische Hochschule (ETH), Universitat ZurichInventors: David Brunner, Benjamin Dietrich, Klaas Prussmann
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Publication number: 20180172784Abstract: The invention relates to a system and a method for tracking position and orientation of an object in a magnetic resonance (MR) apparatus.Type: ApplicationFiled: May 30, 2016Publication date: June 21, 2018Applicants: EIDGENOSSISCHE TECHNISCHE HOCHSCHULE (ETH), UNIVERSITAT ZURICHInventors: David O. Brunner, Christoph Barmet, Klaas P. Prussmann, Thomas Schmid
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Patent number: 9915713Abstract: A method of determining the position of at least one magnetic field probe located within a pre-defined volume of interest within a magnetic resonance (MR) imaging or spectroscopy arrangement comprises applying a spatially and temporally variable magnetic reference field having a unique time-course at every point in said volume of interest during a preselected time window. An MR signal is ac-quired from said magnetic field probe during said time window, and the position of the probe is determined from the probe MR signal.Type: GrantFiled: April 20, 2012Date of Patent: March 13, 2018Assignees: Universitat Zurich, Eidgenossische Technische Hochschule (ETH)Inventors: David Brunner, Christoph Barmet, Klaas Prussmann, Maximilian Häberlin
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Patent number: 9791526Abstract: A dynamic field camera arrangement for monitoring electromagnetic field behavior in a spatial region comprises a main magnetic field and a radiofrequency (RF) field limited to a first RF band, particularly in an MRI or NMR apparatus. The arrangement comprises a magnetic field detector set comprising a plurality of low-frequency magnetic field detectors, each one of said magnetic field detectors comprising a magnetic resonance (MR) active substance, means for pulsed MR excitation of said substance and means for receiving an MR signal generated by said substance, wherein said pulsed excitation and said MR detector signal is in a second RF band that does not overlap said first RF band. The MR signal receiving means comprise a first RF filter which suppresses RF signal from said first RF band and transmits RF signal from said second RF band.Type: GrantFiled: April 23, 2012Date of Patent: October 17, 2017Assignees: Eidgenossische Technische Hochschule (ETH), Universitat ZurichInventors: Christoph Barmet, David Brunner, Bertram Wilm, Klaas Prussmann
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Patent number: 9733318Abstract: A method of observing axial magnetization (Mz) in an object (O) located in a main magnetic field (B0) comprises the step of determining magnetic field intensity (Bp) in at least one magnetic field probe (P) arranged in the neighborhood of the object. The magnetic field probe comprises a magnetic resonance (MR) active substance, means for pulsed MR excitation of the substance and means for receiving an MR signal generated by said substance.Type: GrantFiled: April 23, 2012Date of Patent: August 15, 2017Assignees: Eidgenossische Technische Hochschule (ETH), Universitat ZurichInventors: Klaas Prussmann, Christoph Barmet
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Patent number: 8093899Abstract: A magnetic field probe comprises a sample that exhibits magnetic resonance at an operating frequency, an electrically conductive structure surrounding the sample for receiving a magnetic resonance signal therefrom, and a solid jacket encasing the sample and the conductive structure. The jacket is made of a hardened two-component epoxy system containing a paramagnetic dopant dissolved therein, with the concentration of the dopant being chosen such that the jacket has a magnetic susceptibility that is substantially identical to the magnetic susceptibility of the conductive structure.Type: GrantFiled: April 19, 2007Date of Patent: January 10, 2012Assignee: Eidgenössische Technische Hochschule (ETH) and Universität ZürichInventors: Christoph Barmet, Nicola De Zanche, Klass Prüssmann
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Publication number: 20110115486Abstract: A method for acquiring an image or spectrum of a subject or object residing within the magnetic field of a magnetic resonance apparatus, comprises the steps of: executing a predetermined pulse sequence for applying gradient magnetic fields and for coupling in electromagnetic excitation pulses to induce nuclear magnetic resonance within the subject or object; detecting an electromagnetic signal resulting from said magnetic resonance; and constructing at least one image or magnetic resonance spectrum of said subject or object from said detected electromagnetic signal. According to the invention, said coupling in of the electromagnetic excitation pulse and/or said detecting of the electromagnetic signal are carried out substantially by means of travelling electromagnetic waves.Type: ApplicationFiled: October 18, 2010Publication date: May 19, 2011Applicants: Universitat Zurich, Eidgenossische Technische Hochschule (ETH)Inventors: Jurg Fröhlich, Nicola De Zanche, Klaas Prüssmann, David Brunner
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Publication number: 20090295389Abstract: A magnetic field probe comprises a sample (4) that exhibits magnetic resonance at an operating frequency, an electrically conductive structure (8) surrounding the sample for receiving a magnetic resonance signal therefrom, and a solid jacket (12) encasing the sample and the conductive structure. The jacket is made of a hardened two-component epoxy system containing a paramagnetic dopant dissolved therein, with the concentration of the dopant being chosen such that the jacket has a magnetic susceptibility that is substantially identical to the magnetic susceptibility of the conductive structure.Type: ApplicationFiled: April 19, 2007Publication date: December 3, 2009Applicants: Eidgenossische Technische Hochschule (ETH), Universität ZürichInventors: Klaas Pruessmann, Christoph Barmet, Nicola De Zanche
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Publication number: 20090261828Abstract: A coil assembly for magnetic resonance imaging comprises a sheet (2) of flexible and stretchable dielectric material and at least one electrically conducting coil (4a, 4b) for receiving and/or emitting a radio frequency signal. The coil is attached to and extends along a face of the flexible sheet. At least part of the coil is made of a ribbon shaped braided conductor (6) that is arranged in substantially flat contact with the face.Type: ApplicationFiled: April 17, 2008Publication date: October 22, 2009Applicants: Universitat Zurich, Eidgenossische Technische Hochschule (ETH)Inventors: Jurek Nordmeyer-Massner, Nicola De Zanche, Klass Prussmann
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Patent number: 5877023Abstract: In a tubular pressure chamber a drop of a DNA solution with gold particles suspended therein is atomized at the opening of a cannula by a pressure impact. The fog droplets containing the gold particles and the DNA entrained by them, are pressured by the pressure impact through a restriction at the end of the pressure chamber and thereby accelerated and focused. They subsequently traverse in free flight an evacuated specimen chamber and impact in a narrowly limited target area with a predetermined pulse, cells fixed on a holder, thereby penetrating them.Type: GrantFiled: June 7, 1995Date of Patent: March 2, 1999Assignees: Novartis Finance Corp., Schweizerische Eidgenossenschaft Eidgenossische Technische Hochschule (ETH)Inventors: Christof Sautter, Heinz Waldner, Ingo Potrykus