Abstract: The present invention provides improved methods of differentiating insulin+, glucose responsive islet-like structures from insulin− cells. The invention further provides methods for using insulin+, glucose responsive islet-like structures, as well as the insulin+, glucose responsive cells which comprise said islet-like clusters.
Type:
Application
Filed:
July 29, 2003
Publication date:
June 10, 2004
Applicant:
ES Cell International Pte Ltd.
Inventors:
Diana Clarke, Josephine S. D'Alessandro, Kuanghui Lu, Anlai Wang
Abstract: The present invention relates to a substantially pure population of viable pancreatic progenitor cells, and methods for isolating such cells. The present invention further concerns certain therapeutic uses for such progenitor cells, and their progeny.