Abstract: The invention relates to monoclonal antibodies which are reactive with an epitope in the polypeptide represented by amino acid sequence 236 to 251 or 264 to 279 of the human CGA amino acid sequence. The invention further relates to the use of these monoclonal antibodies in an immunoassay for CGA, to immunoreagents comprising any of these two antibodies, and to test kits for the determination of CGA containing immunoreagents based on both of the monoclonal antibodies.
Abstract: The invention refers to an in vitro method of functionally determining at physiological conditions deficiencies in the lectin pathway of the complement system, the method comprising the steps of (a) providing a sample of mammalian blood, serum, plasma or another body fluid; (b) preventing in the sample the activation of the classical pathway by contacting the sample with an inhibitor of a molecule of the C1 complex of the complement system; (e) preventing in the sample the activation of the alternative pathway; (d) activating the lectin pathway in the sample; and (e) determining in the sample any activation of the autologous C5b-9 complex.
Type:
Grant
Filed:
July 11, 2003
Date of Patent:
September 16, 2014
Assignee:
Euro Diagnostica AB
Inventors:
Johanna Roos, Mohamed R. Daha, Lee H. Bouwman, Cornelis Erik Hack
Abstract: The invention relates to monoclonal antibodies which are reactive with an epitope in the polypeptide represented by amino acid sequence 236 to 251 or 264 to 279 of the human CGA amino acid sequence. The invention further relates to the use of these monoclonal antibodies in an immunoassay for CGA, to immunoreagents comprising any of these two antibodies, and to test kits for the determination of CGA containing immunoreagents based on both of the monoclonal antibodies.
Abstract: An antigen exposing micelle or unordered aggregate comprising at least one carrier, at least one epitope and at least one anchoring molecule, wherein said anchoring molecule comprises at least one anchoring part, intended to anchor the antigen exposing micelle to a surface.
Type:
Application
Filed:
July 10, 2008
Publication date:
November 18, 2010
Applicant:
EURO-DIAGNOSTICA AB
Inventors:
Laura Varas, Anna Ketelsen, Hakan Eriksson
Abstract: Pharmaceutical compositions comprising an antigenic amount of peptides derived from the L1 and L2 OFR's of human papillomavirus type 16 coupled to a carrier or in multimer form.
Abstract: The invention refer to a method for diagnosing the presence of infection of papilloma virus (PV) and of papilloma virus (PV) carrying, especially cervix cancer and condyloma, by the detection of virus specific antigen-antibody complexes in immunossay.
Type:
Grant
Filed:
September 22, 1997
Date of Patent:
August 3, 1999
Assignee:
Euro-Diagnostica AB
Inventors:
Joakim Dillner, Lena Dillner, Hwee-Ming Cheng