Abstract: The present invention relates to methods of producing crosslinked hyaluronic acid microbeads, as well as the produced microbeads, said method comprising the steps of: (a) providing an aqueous alkaline solution comprising hyaluronic acid, or a salt thereof; (b) forming microdroplets having a desired size from the mixed solution of step (a) in an organic or oil phase to form a water in organic or water in oil (W/O) emulsion, wherein the amount of oil phase used is of from 20 to less than 50% by weight based on the sum of oil phase and water; (c) adding a solution comprising a crosslinking agent to the emulsion, whereby the reaction of hyaluronic acid with the crosslinking agent takes place to provide crosslinked hyaluronic acid microbeads; and (d) optionally working up the dispersion of crosslinked hyaluronic acid microbeads obtained in step (c).
Abstract: Alkoxysilyl-functional polyether-siloxanes and processes for preparing them by noble metal-catalysed SiC coupling of hydrogensiloxanes having SiH groups with unsaturated polyethers bearing alkoxysilyl groups or by alkoxylation of polyethersiloxanes or polysiloxanes by means of epoxy-functional alkoxysilanes in the presence of double metal cyanide catalysts.
Type:
Grant
Filed:
November 5, 2009
Date of Patent:
October 9, 2012
Assignee:
Evonik Goldschmidt GmbH
Inventors:
Frank Schubert, Frauke Henning, Wilfried Knott
Abstract: The invention relates to the use of the tetrapeptide PKEK for brightening human skin, for bleaching pigmented spots and/or for leveling out irregularities in skin coloration.
Type:
Application
Filed:
October 18, 2010
Publication date:
September 27, 2012
Applicant:
EVONIK GOLDSCHMIDT GMBH
Inventors:
Mike Farwick, Ursula Maczkiewitz, Tim Koehler
Abstract: Use of one or more mixed curable hydroxyl-containing silyl polyethers as a constituent of compositions, as modifiers for surfaces, the silyl polyethers being prepared by DMC-catalysed alkoxylation of epoxy-functional alkoxysilanes.
Type:
Grant
Filed:
December 3, 2009
Date of Patent:
September 18, 2012
Assignee:
Evonik Goldschmidt GmbH
Inventors:
Thomas Ebbrecht, Frank Schubert, Matthias Naumann, Wilfried Knott, Kathrin Lehmann, Joachim Venzmer, Berend-Jan De Gans, Stefan Silber, Frauke Henning
Abstract: Use of sophorolipids as adjuvants in combination with pesticides as tank mix additive and/or as formulation additive for crop protection and for the industrial non-crop sector.
Type:
Application
Filed:
August 30, 2010
Publication date:
August 30, 2012
Applicant:
EVONIK GOLDSCHMIDT GMBH
Inventors:
Sabine Giessler-Blank, Martin Schilling, Oliver Thum, Ewald Sieverding
Abstract: The present invention related to particles and composite particles, their uses and a novel process for producing them from alkoxysilyl-group-carrying alkoxylation products.
Type:
Grant
Filed:
February 2, 2011
Date of Patent:
August 21, 2012
Assignee:
Evonik Goldschmidt GmbH
Inventors:
Frank Schubert, Matthias Naumann, Wilfried Knott, Joachim Venzmer, Berend-Jan de Gans, Susann Wiechers
Abstract: Silicone-polyether block copolymer comprising a polyorganosiloxane which includes at least one polyether residue having a molecular weight of not less than 5000 g/mol, and wherein a weight average molecular weight of all polyether residues attached to the polyorganosiloxane by a chemical bond is above 3000 g/mol, its production and use and also compositions and polymeric articles obtained therewith.
Type:
Application
Filed:
January 25, 2012
Publication date:
July 26, 2012
Applicant:
EVONIK GOLDSCHMIDT GMBH
Inventors:
Frauke Henning, Annegret Terheiden, Roland Hubel, Sarah Schmitz, Carsten Schiller, Frank Schubert
Abstract: A process for production of polyurethane foams having a density of below 24.0 kg/m3 is provided. The process includes utilizing a silicone-polyether block copolymer comprising a polyorganosiloxane which includes at least one polyether moiety. The polyorganosiloxane has attached to it at least one non-endcapped polyether moiety having a molecular weight of not less than 4500 g/mol. Polyurethane foams and articles which are obtainable by the process of the present invention are also disclosed.
Type:
Application
Filed:
January 25, 2012
Publication date:
July 26, 2012
Applicant:
EVONIK GOLDSCHMIDT GMBH
Inventors:
Roland Hubel, Annegret Terheiden, Carsten Schiller, Frauke Henning, Sarah Schmitz
Abstract: The present invention relates to polyglycerol partial esters of linear, unsubstituted carboxylic acids with the provisos that the polyglycerol obtained by hydrolysis or alcoholysis of the polyglycerol partial ester comprises an average degree of polymerization of from 2 to 8 and the polydispersity index of said polyglycerol is greater than 0.75.
Type:
Grant
Filed:
February 12, 2010
Date of Patent:
July 24, 2012
Assignee:
Evonik Goldschmidt GmbH
Inventors:
Hans Henning Wenk, Ulrike Kottke, Jennifer B. Ponder
Abstract: Process for enzymatically synthesizing carboxylic esters, characterized in that mixing and discharge of the water of reaction are effected by introducing a gas while achieving low effectiveness ratios EV.
Type:
Grant
Filed:
January 15, 2009
Date of Patent:
July 10, 2012
Assignee:
Evonik Goldschmidt GmbH
Inventors:
Oliver Thum, Lutz Hilterhaus, Andreas Liese
Abstract: The invention relates to a novel branched polysiloxanes having quaternary ammonium groups of the general formula (I) as a softening agent for textile sheet materials and fibers, and to a method for the production and use thereof Ma MQb MRc Dd DQe DRf Tg Qh Formula (I).
Abstract: The invention relates to emulsifier systems for cosmetic and pharmaceutical oil-in-water emulsions comprising high molecular weight organomodified polysiloxanes with a dispersion index greater than 1.6.
Type:
Grant
Filed:
September 11, 2009
Date of Patent:
July 3, 2012
Assignee:
Evonik Goldschmidt GmbH
Inventors:
Juergen Meyer, Christian Hartung, Karin Czech, Michael Ferenz, Andrea Lohse, Sascha Herrwerth, Frank Unger, Burghard Gruening
Abstract: The invention provides partially endcapped polyether siloxanes, the use of these polyether siloxanes as foam stabilizers and also rigid polyurethane or polyisocyanurate foams obtained using the polyether siloxanes.
Type:
Application
Filed:
December 14, 2011
Publication date:
June 21, 2012
Applicant:
EVONIK GOLDSCHMIDT GMBH
Inventors:
Martin Glos, Carsten Schiller, Christian Eilbracht
Abstract: A polyether siloxane of formula (I) R1—Si(CH3)2—O—[—Si(CH3)2—O—]n—[—Si(CH3)R—O—]m—Si(CH3)2—R2??(I) where R, R1 and R2 are the same or different, R in each occurrence is the same or different and represents —(CH2)x—O—(CH2—CR?R?—O)y—R??, R? and R? are the same or different and each represent —H, —CH3, —CH2CH3 or phenyl, R?? represents —H, alkyl or acyl, R1 and/or R2 each represent methyl or R, wherein the alkylene oxide units (CH2—CR?R?—O) within a polyether residue R can be the same or different and the polyether residues R within a polyether siloxane molecule of formula (I) can be the same or different, wherein on average (number average, averaged over all compounds of formula (I)) n+m+2=>10 to 200, m=0 to 40 for R1 and/or R2 representing R or m=1 to 40 for R1 and R2 representing —CH3, x=2 to 10, y=1 to 50, at least 25% of the R?? radicals represent hydrogen and at least 50% of all polyether residues R which have an end group R??=—H have a secondary or tertiary OH end group.
Type:
Application
Filed:
December 16, 2011
Publication date:
June 21, 2012
Applicant:
EVONIK GOLDSCHMIDT GMBH
Inventors:
Carsten Schiller, Martin Glos, Christian Eilbracht
Abstract: The invention provides dispersing resins for solids, obtainable by full or partial reaction of A) one or more amino-functional polymers with B) one or more polyesters of the general formula (I)/(Ia) T-C(O)—[O-A-C(O)]x—OH??(I) T1-O—[C(O)-A-O—]y—Z??(Ia) ?and C) one or more polyethers of the general formula (II)/(IIa) T2-B—Z??(II) T-O—B—Z??(IIa).
Abstract: The invention provides a process for preparing siloxanes modified with organic esters, by hydrosilylating siloxanes with terminally unsaturated esters, which comprises preparing the terminally unsaturated esters used using at least one enzyme as catalyst.
Type:
Grant
Filed:
November 6, 2009
Date of Patent:
June 12, 2012
Assignee:
Evonik Goldschmidt GmbH
Inventors:
Michael Ferenz, Burghard Gruening, Christian Hartung, Oliver Thum
Abstract: A process for preparing organopolysiloxanes by reacting linear siloxane compounds (II) and/or cyclic siloxane compounds (III) with a compound having at least one hydroxyl group R?—OH (IV) where R? are identical or different organic radicals, which is characterized in that the compounds of the formulae (II), (III) and (IV) are used in such amounts that the molar ratio of silicon atoms in the compounds of the formulae (II) and (III) to OH groups in the compounds of the formula (IV) is from 0.01:1 to 1000:1, and in that the reaction is performed at a temperature of greater than 70° C. to 175° C., and in that the resulting reaction mixture is not treated with an acidic compound.
Abstract: The present invention relates to the use of at least one ether guanidine of the general formula (I) and/or of a salt or hydrate thereof, in which R1?—CH2—CH2—CH2—O—R3, where R3 is a linear or branched hydrocarbon radical having 6 to 22 carbon atoms, and R2?H or an optionally branched hydrocarbon radical which has 1 to 22 C atoms and which optionally comprises double bonds, for reducing the growth of microorganisms, and to cosmetic and pharmaceutical formulations comprising at least one ether guanidine of the general formulae (I).
Type:
Application
Filed:
July 19, 2010
Publication date:
May 31, 2012
Applicant:
EVONIK GOLDSCHMIDT GMBH
Inventors:
Oliver Springer, Peter Muss, Peter Lersch, Ursula Maczkiewitz, Mike Farwick
Abstract: Water repellents based on reactive siloxanes with polyfunctional silylalkoxy modification of the siloxane backbone and processes for hydrophobizing mineral fiber components.
Type:
Grant
Filed:
August 5, 2009
Date of Patent:
May 8, 2012
Assignee:
Evonik Goldschmidt GmbH
Inventors:
Sascha Herrwerth, Frank Koenig, Michael Ferenz, Christian Mund
Abstract: The invention provides solvent-free release agents for producing polyurethane moldings, substantially including: A) at least one wax having release activity; B) at least one oil having release activity; and C) if desired, further auxiliaries and adjuvants, with the proviso that the release agent contains no water and no volatile organic solvent, and the oil with release activity is substantially free from unsaturated hydrocarbons.