Patents Assigned to Forschungszentrum Jülich GmbH
  • Patent number: 10786675
    Abstract: A device for stimulating neurons that includes a stimulation unit implantable in the body of a patient and having stimulation elements that stimulate neurons in the brain and/or spinal cord. A control unit controls the stimulation unit during first and second time intervals in different stimulation modes. The control unit controls the stimulation unit during 75% or more of the first time interval in the first stimulation mode to repeatedly generate sequences of stimuli and the order in which the stimulation elements generate stimuli is constant for not more than 5 successively generated sequences and then varied. The control unit controls the stimulation unit during 75% or more of the second time interval in a second stimulation mode such that the stimulation elements repeatedly generate sequences of stimuli and the order in which the stimulation elements generate stimuli is constant for at least 25 successively generated sequences and then varied.
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: September 29, 2020
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Peter Alexander Tass, Magteld Zeitler
  • Patent number: 10772321
    Abstract: The invention relates to the treatment of blood, blood products and organs for the removal and/or detoxification of amyloid-beta oligomers.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: September 15, 2020
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventor: Dieter Willbold
  • Patent number: 10760104
    Abstract: The invention relates to a method of producing D-xylonate from D-xylose, which includes converting D-xylose to D-xylonate from a coryneform bacterium in which the activity of the iolR gene is reduced or completely switched off compared with the wild type or a mutation of the wild type, or the iolR gene is completed or partially deleted, as well as to a bacterium for carrying out the method.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: September 1, 2020
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Stephan Noack, Andreas Radek, Jan Marienhagen, Karin Krumbach
  • Patent number: 10752555
    Abstract: A method for producing a transparent polycrystalline ceramic includes forming at least one planar transparent region near a surface within the ceramic, wherein the at least one planar transparent region has a lower thermal expansion coefficient than other regions of the ceramic. The method further includes generating compressive stresses in the at least one planar transparent region near the surface after a thermal treatment and cooling.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: August 25, 2020
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Olivier Guillon, Marc Rubat Du Merac, Martin Bram
  • Patent number: 10746747
    Abstract: A method for the quantitative characterization of substances with regard to their properties of binding to amyloid-? (A?) conformers, comprising the steps of: —fractionating a sample including various A? conformers; —immobilizing a biotinylated A? conformer of the desired fraction on the surface of a substrate having high affinity for biotin; and —deriving the binding behavior of an aggregate quality control probe to the desired A? conformer from the measurement signal by determining the kinetic and/or thermodynamic parameters. A device for carrying out the method.
    Type: Grant
    Filed: June 25, 2014
    Date of Patent: August 18, 2020
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Dieter Willbold, Julian Glueck, Daniel Frenzel, Luitgard Nagel-Steger, Oleksandr Brener
  • Patent number: 10739298
    Abstract: The invention relates to a method for producing a device for the electrochemical detection of molecules by way of redox cycling, to a device therefor, and to the use thereof. A porous dielectric layer is present between two electrode layers, which is able to receive redox-active molecules and may be biofunctionalized. The individual layers are preferably applied by way of an ink jet printing method.
    Type: Grant
    Filed: April 9, 2016
    Date of Patent: August 11, 2020
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Alexey Yakushenko, Bernhard Wolfrum, Nouran Yehia Adly Hassan, Andreas Offenhausser
  • Patent number: 10722678
    Abstract: A device for stimulating neurons that includes a non-invasive stimulation unit for generating stimuli in stimulation channels. A control unit controls the stimulation unit during first and second time intervals in different stimulation modes. The control unit controls the stimulation unit during 75% or more of the first time interval in the first stimulation mode to repeatedly generate sequences of stimuli and the order in which the stimulation channels generate stimuli is constant for not more than 5 successively generated sequences and then varied. The control unit controls the stimulation unit during 75% or more of the second time interval in a second stimulation mode such that the stimulation channels repeatedly generate sequences of stimuli and the order in which the stimulation channels generate stimuli is constant for at least 25 successively generated sequences and then varied.
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: July 28, 2020
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Peter Alexander Tass, Magteld Zeitler
  • Patent number: 10707637
    Abstract: The invention concerns a maser having an electromagnetic resonant circuit comprising a pick-up coil, a capacitance and a filter coil, an active medium of organic or maser-capable molecules in the pick-up coil as well as a population inversion device for generating a population inversion in the active medium.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: July 7, 2020
    Assignee: Forschungszentrum Jülich GmbH
    Inventors: Stephan Appelt, Martin Süfke
  • Publication number: 20200208184
    Abstract: A method of producing 5-ketofructose using an acetic acid bacterium which is genetically modified to express a fructose dehydrogenase as well as to microorganisms which can be used in said method.
    Type: Application
    Filed: June 13, 2018
    Publication date: July 2, 2020
    Applicants: RWTH Aachen, Forschungszentrum Jülich GmbH, Rheinische Friedrich-Wilhelms-Universität Bonn
    Inventors: Elena Herweg, Jochen Büchs, Michael Bott, Ines Kiefler, Uwe Deppenmeier, Konrad Kosciow, Anna Siemen
  • Publication number: 20200198048
    Abstract: A method for generating a structured surface on a substrate includes analyzing a substrate surface of the substrate and selecting, as a function of a condition of the substrate surface, method parameters including focus diameter, pulse peak power, pulse energy, point spacing, pulse length, pulse spacing and/or pulse sequence. The method further includes generating, by partial ablation and partial deposition via treatment with an intensive pulsed laser beam, surface structures having dimensions in the sub-micrometer range such that a multi-scale surface structure in the sub-micrometer and micrometer range adapted to intrinsically inhomogeneous properties of the substrate surface in the sub-micrometer range is generated. The substrate is an inhomogeneous substrate.
    Type: Application
    Filed: June 13, 2018
    Publication date: June 25, 2020
    Applicant: Forschungszentrum Jülich GmbH
    Inventors: Caren Sophia GATZEN, Daniel Emil MACK, Martin TANDLER, Robert VASSEN
  • Patent number: 10670670
    Abstract: The problem addressed by the invention is that of providing a coil having advantageous properties for an oscillating circuit, in particular for a measuring device for electromagnetic signals. This problem is solved in that the coil comprises an electric conductor, the ends of which form the two terminals of the coil. Wound sections of the electric conductor are twisted together, that is to say wound helically around one another. The electric conductor is in principle surrounded by insulation, for example made of plastic or varnish. As a result of the twisting, increases in spacing between adjacent conductor sections within the windings are achieved. This results in an improved quality of the coil.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: June 2, 2020
    Assignee: Forschungszentrum Jülich GmbH
    Inventors: Stephan Appelt, Martin Süfke, Bernd Alexander Liebisch
  • Patent number: 10644227
    Abstract: The present disclosure concerns a magnetic tunnel diode and a magnetic tunnel transistor. The magnetic tunnel diode may include two terminals for connecting to an electrical circuit as well as a tunnel junction. The magnetic tunnel transistor may include three terminals for connecting to an electrical circuit as well as a layer arrangement.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: May 5, 2020
    Assignee: Forschungszentrum Jülich GmbH
    Inventors: Ersoy Şaşio{hacek over (g)}lu, Stefan Blügel
  • Patent number: 10637083
    Abstract: The invention relates to a method for ascertaining the overvoltage of a working electrode in a fuel cell, in which the potential of a reference electrode compared to the grounded counter electrode is measured. For the measurement, a fuel cell comprising a polymer electrolyte membrane is used, in which the counter electrode comprises a lateral edge having at least one convexly curved region, and the electrolyte membrane surface, adjoining the counter electrode, comprises an electrode-free region in which the reference electrode is disposed on the electrolyte membrane surface. In contrast, the working electrode is continuous, which is to say has a large surface.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: April 28, 2020
    Assignee: Forschungszentrum Juelich GmbH
    Inventor: Andrei Kulikovsky
  • Patent number: 10617869
    Abstract: A device that suppresses a pathological synchronous and oscillatory neuron activity, and includes a non-invasive stimulation unit implantable in a patient, for stimulation, using electrical and/or optical stimuli, of neurons in the patient's brain and/or spinal cord, where those neurons are showing pathologically synchronous and oscillatory neuron activity, and the stimuli are deigned to suppress are this activity when administered to the patient. Moreover, a measuring unit records measurement signals reflecting the neuron activity of the stimulated neurons and a control and analysis unit controls the stimulation unit to administer stimuli, check the success of stimulation based on the measurement, and, if the stimulation success is not sufficient, insert one or more stimulation breaks in the application of the stimuli or extend one or more stimulation breaks, where no stimuli that could suppress the pathological synchronous and oscillatory neuron activity are applied during the stimulation breaks.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: April 14, 2020
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Peter Alexander Tass, Oleksandr Popovych, Markos Xenakis
  • Patent number: 10605931
    Abstract: A SiPM sensor chip with a plurality of pixels includes a photodiode; a quench resistor; and a current divider configured to divide the photocurrent of the photodiodes into two currents of equal size. The current divider Sq,nm or Snm lead to networks NS,h,n and NS,V,m, each of which leads to additional current dividers Sh,n and Sv m having coding resistors Rh,A,n and Rh,B,n, and Rv,c,m and Rv D m, which are linearly coded and which lead to output channels A, B, C, D, with these sensor features being integrated into the sensor chip. The networks Ns,h,n and/or NSiVlm each lead to a summation network Oh and/or Ov, in which the signals of the networks Ns,h,n and/or NS,v,m are merged via summation resistors Rs,h,n and Rs,v,m, respectively, and lead to the output channels E and/or F.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: March 31, 2020
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Christoph Lerche, Arne Berneking, Joni Nadim Shah
  • Patent number: 10607804
    Abstract: The present invention refers to a device for generating charged particle beams with tunable orbital angular momentum. The device firstly includes one or more components for providing a charged particle beam. It is further characterized by an electrical arrangement for imparting a tunable orbital angular momentum to the charged particle beam during operation. The orbital angular momentum of the produced charged particle vortex beam is tunable by adjusting the amount of electrical current. The chirality of the produced charged particle vortex beam is switchable by reversing the direction of the electrical current. The generation of the charged particle vortex beam from the present invention does not depend on the energy of the charged particle beams. The generation of the charged particle vortex beams from the present invention is predictable and reproducible.
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: March 31, 2020
    Assignee: Forschungszentrum Jülich GmbH
    Inventors: Amir Tavabi, Penghan Lu, Martial Duchamp, Rafal Edward Dunin-Borkowski, Giulio Pozzi
  • Patent number: 10593762
    Abstract: Transferring graphene pieces onto a substrate, by the following steps: a) selecting a substrate comprising a plurality of placeholders for the graphene pieces; b) disposing and aligning the substrate on a substrate holder in a chamber; c) selecting a transfer layer having openings as placeholders for the graphene pieces; d) disposing and aligning the transfer layer on the substrate holder over the substrate so that the openings of the transfer layer are aligned over the placeholders on the substrate; e) adding liquid to the chamber to above the transfer layer, and raising the transfer layer on the liquid column; f) introducing graphene pieces onto the liquid film in the openings of the transfer layer; and g) reducing the distance between the substrate and the graphene pieces until the graphene pieces are disposed on the placeholders of the substrate. A substrate and a device for carrying out the method.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: March 17, 2020
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Dmitry Kireev, Dario Sarik, Bernhard Wolfrum, Andreas Offenhausser
  • Patent number: 10585116
    Abstract: A scanning probe microscope includes a tip. A quantum dot is applied to the tip.
    Type: Grant
    Filed: January 18, 2016
    Date of Patent: March 10, 2020
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Frank Stefan Tautz, Ruslan Temirov, Christian Wagner, Matthew Felix Blishen Green
  • Patent number: 10566654
    Abstract: A method for preparing electrolyte material having a NASICON structure, based on a Na3+xScxZr2?x(SiO4)2(PO4) compound where 0?x<2. The method includes providing an acidic, aqueous solution which, according to a desired stoichiometry, comprises sodium, scandium and zirconium in the form of water-soluble nitrates, acetates or carbonates, and soluble silicates or orthosilicic acids or organic silicon compounds in dissolved form; subsequently adding phosphoric acid or ammonium dihydrogenphosphate or other soluble phosphates, according to the desired stoichiometry, complex zirconium dioxide phosphates forming as colloidal precipitations; and subsequently drying and calcining the mixture.
    Type: Grant
    Filed: August 27, 2016
    Date of Patent: February 18, 2020
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Qianli Ma, Frank Tietz, Sahir Naqash, Olivier Guillon
  • Patent number: 10557051
    Abstract: A method for producing an ink includes providing nanoparticles having a size of 0.1 to 20 nm maximum by wet milling using a solvent and covalently bonding, by means of a coupling reaction, short-chain, branched organic stabilizer molecules to the surface of the nanoparticles. The method additionally includes absorbing the stabilized nanoparticles in a solvent for producing the ink and dispersing the stabilized nanoparticles.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: February 11, 2020
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Alexey Yakushenko, Stefanie Hamacher, Dirk Mayer, Andreas Offenhaeusser