Abstract: A chemiresistive vapor sensor compound for detecting target vapors can comprise a perylene-tetracarboxylic diimide (PTCDI) core according to structure (I): where R can be a morphology control group or -A?-D?, A and A? can be independently a linking group, D and D? can be independently a strong electron donor which transfers electrons to the PTCDI core sufficient to form an anionic PTCDI radical of the PTCDI core, and R1 to R8 can be independently a side group. A chemiresistive vapor sensor for detection of a target compound can comprise an assembly of nanofibers formed of the chemiresistive sensor compound and a pair of electrodes operatively oriented about the assembly of nanofibers to allow electrical current to pass from a first electrode in the pair of electrodes through the assembly of nanofibers and to a second electrode in the pair of electrodes.

Abstract: Disclosed herein are cell culture analog devices, systems and methods for applying stimuli to components containing different cell types and recording the cell responses before, during, and after a stimulus (for example, a drug, metabolite, toxin, or electrical stimulus) is introduced. Responses can be stored to a database and compared to previous results. By analyzing how each cell type responds to various stimulation parameters, for example, by using multivariate analyses, cell signaling pathway information can be determined or new pathways can be discovered. In some implementations, an individual component interfaces with a specific cell type. This facilitates readout of the cell response to the stimulation. Various components can also interface with each other, such that the behavior of one cell type can affect a cell type in another component. Once assembled, the system is plugged into readout electronics and a programmable electrical stimulator.

Abstract: The infrared denaturing device of the present invention is provided with: an infrared lamp which emits infrared light; a light guide which guides the infrared light; and a light projecting body which radiates the infrared light guided from the light guide onto an object to be denatured. The light projecting body is provided with: a reflecting surface which reflects the infrared light; and a radiating surface which radiates the infrared light reflected by the reflecting surface onto an object to be irradiated. Further, there is also provided a denaturing detection sensor which detects denaturing, by means of the infrared light, of a region being denatured.

Abstract: The effects of hepcidin treatment on mitigating ischemia reperfusion injury (IRI) and acute kidney injury (AKI) by decreasing iron availability and ROS-mediated cell death were tested. Wild type (WT) C57Bl/6 and hepcidin knock out (Hamp?/?) mice were treated with saline or 50 ?g of hepcidin i.p. prior to bilateral renal IRI. Renal function, injury markers, histopathology, and inflammation were examined after 24 hours of reperfusion. In WT mice, IRI induced increases in serum and kidney non-theme iron levels, but hepcidin treatment induced sequestration of iron in the spleen and liver and prevented IRI-associated increases in serum and kidney non-heme iron. Kidney function was significantly better in hepcidin-treated mice, accompanied by less acute tubular necrosis and reduced infiltration of immune cells. Hepcidin treatment decreased kidney ferroportin expression and induced the expression of cytoprotectant, H-Ferritin, and was associated with less ROS and tubular epithelial apoptosis.

Abstract: The present invention relates to a novel brominated furanone derivative, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient, wherein the novel brominated furanone derivative or a pharmaceutically acceptable 5 salt thereof according to the present invention exhibits a quorum sensing inhibitory activity of bacteria and also can effectively inhibit the formation of biofilm of bacteria, and thus can be used as a pharmaceutical composition containing the same as an active ingredient, thereby having an effect of being useful, 10 for example, for periodontal diseases such as gingivitis and periodontitis, oral diseases, and the like.

Abstract: A pedal that includes a pedal body having a clipless structure and a member. The clipless structure includes a lip at a first portion of the pedal and a cleat at a second portion of the pedal. The pedal includes a detachable shoe platform having a cleat portion securable to the lip and a clip securable to the member. The detachable shoe platform may include an adjustable toe clip having a strap, which wraps around a shoe of a rider. The strap is adjustable by an adjustable strap fastener assembly having a lever coupled to a plate secured in a housing. The lever includes a first end biased against the strap and a second end engaged by a trigger. The trigger is operable to move the lever from a closed position to an open position against the bias force, thereby releasing the strap for adjustment.

Abstract: An integrated dual-modality microfluidic sensor chip and methods for using the same. In one form, the sensor comprises a patterned periodic array of nanoposts coated with a noble metal and graphene oxide (GO) to detect target biomarker molecules in a limited sample volume. The device generates both electrochemical and surface plasmon resonance (SPR) signals from a single sensing area of the metal-GO nanoposts. The metal-GO nanoposts are functionalized with specific receptor molecules, serving as a spatially well-defined nanostructured working electrode for electrochemical sensing, as well as a nanostructured plasmonic crystal for SPR-based sensing via the excitation of surface plasmon polaritons.

Abstract: According to an exemplary embodiment, a capacitively coupled continuous-time delta-sigma modulator includes an instrumentation amplifier amplifying an input voltage to an output voltage of a predetermined magnitude, a delta-sigma modulator outputting a bit signal quantized depending on a sampling frequency based on the output voltage and to convert the bit signal into a digital-to-analog conversion voltage, and a ripple reduction loop unit generating a demodulation voltage, in which a ripple is removed from the output voltage, depending on an RRL operating frequency to feed the demodulation voltage back to the instrumentation amplifier. The RRL operating frequency is equal to the sampling frequency.

Abstract: The subject invention concerns materials and methods for alkene reduction of compounds, such as levoglucosenone (LGO) and (S)-?-hydroxymethyl-?,?-butenolide (HBO), using an alkene reductase enzyme. In one embodiment, a method of the invention comprises alkene reduction of a target compound by reacting the compound with an Old Yellow Enzyme (OYE) that reduces alkene bonds. In one embodiment, the OYE is OYE 2.6 from Pichia stipites and comprises the amino acid sequence of SEQ ID NO: I. In a specific embodiment, the enzyme is an Old Yellow Enzyme (OYE) 2.6 mutant having an amino acid substitution at position 78 in the sequence, wherein the tyrosine at position 78 is substituted with a tryptophan amino acid (Y78W) and is designated as OYE 2.6 Y78W (SEQ ID NO:2).

Abstract: An external preparation for skin and an aerogel paste are provided. The external preparation for skin comprises aerogel powder and a solvent. The aerogel powder includes a mixture of aerogel particles having a hydrophilic functional group on a surface thereof and aerogel particles having a hydrophobic functional group on a surface thereof. The hydrophilic functional group is a hydroxy group, and the hydrophobic functional group is hydrogen, a C1 to C18 alkyl group, a silyloxy group represented by the following Chemical Formula 1, or a combination thereof: [Chemical Formula 1] *—OSiH(3-n)R1n wherein R1 is a C1 to C18 alkyl group, n is an integer ranging from 0 to 3, and * denotes a bond.

Abstract: The invention provides enrichment platform devices for size-based capture of particles in solution. The enrichment platform device is useful for label-free capture of any particle. The invention relates to enrichment platform devices using nanowires and vertically aligned carbon nanotubes. The invention provides methods for making the enrichment platform devices. The invention provides methods for using the enrichment platform devices for filtering particles, capturing particles, concentrating particles, and releasing viable particles.

Abstract: A three-axis magnetic sensor which is not physically separated from each other and made of one element is provided. A spin-orbit torque is generated through an interface junction between a magnetization seed layer and a magnetization free layer, and through this, a change in an in-plane magnetic field may be sensed in the form of current or voltage in the magnetization seed layer. Further, a tunneling insulating layer and a magnetization pinned layer are formed on the magnetization free layer. The formed structure induces a tunnel magneto-resistance phenomenon. Through this, a change in a magnetic field in a vertical direction is sensed.

Abstract: The present invention relates to methods for fabricating vertical homogenous and heterogeneous two-dimensional structures, the fabricated vertical two-dimensional structures, and methods of using the same. The methods demonstrated herein produce structures that are free standing and electrically isolated.

Abstract: An electronic memory array includes a plurality of memory domains, a current controller, and a selector device. Each memory domain includes a plurality of bit cells. The current controller includes a current controller output electrically connectable to said plurality of memory domains and is configured to control a bit cell current. The selector device is electrically connected to the current controller and the plurality of memory domains. The selector device is configured to selectively electrically connect the current controller output to only a select one of said memory domains, such that the current controller controls only the bit cell current of the bit cells of the select memory domain.

Abstract: Multiple spatially diverse and compact weight sensors are statistically combined to reduce or eliminate errors caused by snow bridging. Data transmission using satellite communication minimizes the power consumption of the sensor station further allowing the entire system to be relatively compact and easily transported. The weight sensors may be combined with other standard sensors for measurement of air temperature and snow height, the latter measurement, for example, using ultrasound ranging or the like.

Abstract: The present disclosure relates to compositions and methods for enhancing mosquito feeding.

Abstract: The present invention relates to adenovirus E4ORF1 gene and to endothelial cells engineered to express the E4ORF1 gene. The present invention also relates to uses of the E4ORF1 gene, and cells expressing the E4ORF1 gene, and to compositions comprising the E4ORF1 gene, or comprising cells expressing the E4ORF1 gene.

Abstract: Disclosed is an apparatus including: a photovoltaic panel; a CPG controller configured to receive a limit output power value of a photovoltaic panel, a photovoltaic panel terminal voltage, and a photovoltaic panel output current and output a photovoltaic panel terminal voltage reference; a direct current (DC)-voltage controller configured to receive the photovoltaic panel terminal voltage reference and the photovoltaic panel terminal voltage and output a duty ratio to cause an error between these values to become zero; a pulse width modulation (PWM) control signal generator configured to receive the duty ratio and output a PWM signal to control a DC/DC converter connected to the photovoltaic panel; the DC/DC converter configured to receive the PWM signals and perform CPG control; and a DC/AC inverter connected to the DC/DC converter and configured to convert DC power into AC power and output the AC power to an electrical grid.

Abstract: The present invention provides a composition for antifreezing including a gold (Au) nanostructure in which at least a portion thereof is concave, thereby it is possible to increase a survival rate of cells due to having excellent effect of inhibiting ice recrystallization when cryopreservation of the cells, and maintain a texture of food even when using in the freezing of food.

Abstract: A deep neural network accelerator includes a unit array including a first sub-array including a first operational unit and a second sub-array including a second operational unit. The first and second operational units have different sizes from each other, the sizes of the first and second operational units are in proportion to each cumulative importance value accumulated in each operational unit of the unit array while performing a deep neural network operation, and the each cumulative importance value is obtained by accumulating an importance for each weight mapped to the each operational unit of the unit array.