Abstract: The present invention provides a digestive organ endoscope system which allows a user to perceive whether or not the tip of an endoscope instrument inserted along a channel approaches the tip of an endoscope channel portion within a certain distance, thereby being capable of quickly inserting the endoscope instrument up to a position close to the tip of the endoscope channel portion, and thus, it is possible to reduce a procedure time and to prevent a digestive organ from being damaged due to instantaneous protrusion of the tip of the endoscope instrument occurring when the endoscope instrument is quickly inserted.

Abstract: The present disclosure relates to a method of preparing a graphene metal nanoparticle-composite, including: preparing graphene by applying a shearing force to a first solution containing a graphite-based material and thus exfoliating the graphite-based material; preparing metal nanoparticles by applying a shearing force to a second solution containing a metal precursor, a capping agent, and a reducing agent; and physically combining the metal nanoparticles on the graphene by applying a shearing force to a third solution containing the graphene and the metal nanoparticles, and a graphene metal nanoparticle-composite prepared according to the method.

Abstract: The present invention relates to a metal oxide nanoparticle ink composition, a method of producing the same, and a method of forming a conductive layer pattern by using the metal oxide nanoparticle ink composition, and more particularly, to a metal oxide nanoparticle ink composition for forming a conductive layer by irradiating an ink composition thin film containing nickel oxide nanoparticles with a sintering laser, a method of producing the same, and a method of forming a conductive layer pattern by using the metal oxide nanoparticle ink composition.

Abstract: Disclosed is a microneedle including: a needle part including a plurality of tips formed from a liquid formulation formed with a medicinal solution and capable of penetrating the skin; and a base for supporting the plurality of tips; and a guide part configured to guide the needle part to penetrate the skin, wherein the needle part is provided with separation guides formed between the tips and the base to separate the tips from the base. According to such a configuration, the tips rapidly penetrate the skin and are rapidly separated therefrom, which allows quantitative drug delivery.

Abstract: Disclosed are a microneedle, an apparatus for manufacturing a microneedle including a support part containing a medicinal solution for coating a microneedle, a controller for controlling the temperature of the medicinal solution contained in the support part, and a dryer for drying the medicinal solution coated on the microneedle, and a method of manufacturing the microneedle using the apparatus. According to the configuration, the temperature of the medicinal solution can be adjusted such that a viscosity suitable for coating with the medicinal solution is maintained, whereby the quality of a microneedle coated with the medicinal solution can be improved, and denaturation of active ingredients in the medicinal solution can be prevented, which causes stability increase.

Abstract: Discloses is a method of manufacturing a micro-needle. The method includes a step of preparing a medicinal solution, a step of forming a plurality of tips with the medicinal solution, and a step of forming a cavity in each of the tips. In accordance with such a configuration, a micro-needle in which cavities are formed is provided, whereby it is possible to administer a fixed amount of medicine in a short time.

Abstract: The present invention relates to a method for improving the migration ability of stem cells into cancer cells comprising educating the stem cells by treating the stem cells with an in vitro cell culture medium of cancer cells obtained from a cancer patient to be treated and optionally an anionic channel activator.

Abstract: Disclosed is a multi-axially variable detection module of a PET apparatus, the detection module including: a gantry having a through-hole extending from a side to an opposite side of the gantry; a detection module in which a plurality of detectors for detecting gamma rays emitted from a subject are arranged annularly along an inner circumference of the gantry; and a driving means for moving the plurality of detectors constituting the detection module in a radial direction of the detection module, wherein each of the plurality of detectors is rotatable in a longitudinal direction of the detection module to vary a length thereof in the longitudinal direction, and each of the plurality of detectors include multiple detector elements which are engaged with each other in a hinged manner in a transverse direction (circumferential direction) of the detection module to form a flat or an arc shape.

Abstract: The present invention relates to a pharmaceutical composition comprising a STT compound as an active ingredient for the prevention or treatment of Parkinson's disease. STT showed neuroprotective effect and apoptosis recovery effect in the Parkinson's disease cell model, restored the reduced motility in the MPTP animal model, and was shown to significantly protect dopamine cells, so it can be used for the prevention and treatment of Parkinson's disease.

Abstract: The present invention relates to a data analysis method and system for disease diagnosis aid, and more specifically, to a technique and system capable of providing analysis results through integrated analysis of clinical, MRI images, and genotypic data to aid in disease diagnosis. The method includes receiving medical data of a subject; selecting disease-related data using the medical data; and calculating the disease probability according to the selected disease-related data. The medical data provides a configuration including clinical records, genetic and genetic variants, and MRI.

Abstract: A method for preparing a three-dimensional graphene structure, and an energy storage device are provided, the method including forming a graphene precursor by heating a carbohydrate and a gas generator, forming a graphene structure having a cavity therein by carbonizing the graphene precursor, and forming nanopores in the graphene structure, wherein the nanopores pass through an outer surface and an inner surface of the graphene structure, and are connected with the cavity.

Abstract: Disclosed are a biochip for measuring blood glucose levels and a blood glucose meter for a smartphone including the same. The biochip for measuring blood glucose levels includes: a substrate, one surface of which is provided with a blood glucose inflow region into which blood glucose flows and with a reaction region that is connected to the blood glucose inflow region and has a recess formed therein, a porous separator disposed on the blood glucose inflow region to face the surface of the substrate, and silica nanoparticles and a reaction reagent distributed on the reaction region of the substrate. Thereby, blood glucose levels can be measured using such a biochip, which is easy to carry, together with a CMOS image sensor, and particularly, blood glucose levels can be simply measured using a CMOS image sensor provided to a smartphone, and blood glucose levels can be quantitatively measured and checked using a blood glucose meter application installed on a smartphone.

Abstract: The present invention provides a polysilicon-based 1T DRAM cell device having a FinFET structure and its fabrication method. In the present invention, a semiconductor layer (for example, a polysilicon layer) having a relatively low crystallinity is intentionally formed on the upper layer of the active fin to physically trap the holes accumulated in the conventional cell body, thereby remarkably improving the retention time. A polysilicon-based 1T DRAM cell device having a FinFET structure can also increase the operating efficiency by raising the gate's channel control force and implement the batch process with the functional blocks in the CPU that already have the FinFET structure.

Abstract: A p-channel tri-gate transistor has a silicon fin that protrudes from a bulk silicon substrate, a thin silicon-germanium active layer is formed on three sidewalls of the silicon fin, and a hole well is formed between the gate insulating film and the silicon fin in the active layer surrounded by the tri-gate by a valence band offset electric potential against the silicon fin for moving holes collected in the hole well along the active layer with a high hole-mobility. Thus, it is possible to have the effects of not only an ultra-high speed, low power operation, but also a body biasing through an integral structure of the silicon fin-body. The p-channel tri-gate transistor can be fabricated together with an n-channel FinFET transistor in one substrate by the same CMOS process.

Abstract: The present invention relates to a method for detecting apoptosis using a phosphatidylinositol phosphate-binding material, a method for screening anticancer agents, a method for screening apoptosis-inhibiting materials, and a method for inhibiting phagocytosis.

Abstract: The present invention relates to a pharmaceutical composition for treating corneal disease containing 8-oxo-deoxyguanosine (8-oxo-2?-deoxyguanosine) or a pharmaceutically acceptable salt thereof as an active ingredient. Specifically, by confirming that a corneal epithelium was restored (regenerated) quicker and the clarity of a cornea improved when it was administered W to a mouse model of corneal disease induced by ethanol, 8-oxo-deoxyguanosine (8-oxo-2?-deoxyguanosine) of the present invention may be useful for the treatment of corneal disease.

Abstract: Disclosed are a microneedle, an apparatus for manufacturing a microneedle including a support part containing a medicinal solution for coating a microneedle, a controller for controlling the temperature of the medicinal solution contained in the support part, and a dryer for drying the medicinal solution coated on the microneedle, and a method of manufacturing the microneedle using the apparatus. According to the configuration, the temperature of the medicinal solution can be adjusted such that a viscosity suitable for coating with the medicinal solution is maintained, whereby the quality of a microneedle coated with the medicinal solution can be improved, and denaturation of active ingredients in the medicinal solution can be prevented, which causes stability increase.

Abstract: Provided are a composition for target-specific photothermal therapy and a method of photothermal therapy using the composition and more particularly, a method of photothermal therapy for selectively killing inflammatory cells by using the composition for target-specific photothermal therapy comprising carbon nanotubes coated with dextran. According to the present invention, the composition for photothermal therapy comprising the carbon nanotubes coated with dextran is absorbed only into desired target cells, i.e., inflammatory cells, and causes thermotherapeutic action through light irradiated from an external light source, while not damaging cells except for inflammatory cells. The method of photothermal therapy using the composition for photothermal therapy has advantages of minimizing side effects and maximizing therapeutic effects.

Abstract: Provided is a ceramic catalyst which may include a nanostructure composed of ionic salts; and catalyst particles attached to the surface of the nanostructure.

Abstract: Provided are a microneedle electrode sensor for nonenzymatic monitoring of blood sugar, a method of manufacturing the sensor, and a method of nonenzymatically measuring blood sugar using the sensor. The method of manufacturing the microneedle electrode sensor includes (a) forming multiple microneedle shapes in a substrate, (b) coating the entire area of the substrate with a passivation agent, and (c) coating a microneedle reactive portion disposed at a tip of each microneedle with a glucose oxidation catalyst.