Patents Assigned to Genesoft Pharmaceuticals, Inc.
  • Publication number: 20110178074
    Abstract: The present invention is related to methods of treating bacterial infections in mammals using antipathogenic benzamide compounds having the formula wherein at least one of the R1 groups is F, Cl, CN or CF3 and R2, R3, Y, Z, m, and n are as defined herein.
    Type: Application
    Filed: January 25, 2008
    Publication date: July 21, 2011
    Applicant: GeneSoft Pharmaceuticals, Inc.
    Inventors: Roland W. BURLI, Jacob Kaizerman, Peter Jones
  • Publication number: 20090247513
    Abstract: Benzothiophene compounds such as are DNA binding compounds exhibiting antibacterial activity.
    Type: Application
    Filed: December 4, 2007
    Publication date: October 1, 2009
    Applicant: GeneSoft Pharmaceuticals, Inc.
    Inventors: Roland W. Burli, Eldon E. Baird, Matthew J. Taylor, Jacob A. Kaizerman, Wenhao Hu
  • Patent number: 7498405
    Abstract: Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: March 3, 2009
    Assignee: GeneSoft Pharmaceuticals, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Roland W. Burli, Jacob A. Kaizerman, Amanda E. Martin, Brie Cadman
  • Patent number: 7498349
    Abstract: Aromatic compounds exemplified by exhibit antimicrobial activity.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: March 3, 2009
    Assignee: Genesoft Pharmaceuticals, Inc.
    Inventors: Roland W. Burli, Eldon E. Baird, Jacob A. Kaizerman, Dustin L. McMinn
  • Publication number: 20080200465
    Abstract: The present invention is related to methods of treating viral and protozoan infections in mammals using antipathogenic benzamide compounds having the formula wherein at least one of the R1 groups is F, Cl, CN or CF3 and R2, R3, Y, Z, m, and n are as defined herein.
    Type: Application
    Filed: January 25, 2008
    Publication date: August 21, 2008
    Applicant: GeneSoft Pharmaceuticals, Inc.
    Inventors: Roland W. BURLI, Jacob Kaizerman, Peter Jones
  • Publication number: 20080090816
    Abstract: Compounds represented by the formula where R1, R2, R3, R4, R5, and Q are as defined herein, exhibit activity against infectious pathogens.
    Type: Application
    Filed: August 2, 2007
    Publication date: April 17, 2008
    Applicant: Genesoft Pharmaceuticals, Inc.
    Inventors: Peter Jones, Roland Burli, Chun Jiang, Dustin McMinn
  • Patent number: 7348427
    Abstract: Antipathogenic benzamide compounds having the formula wherein at least one of the R1 groups is F, Cl, CN or CF3 and R2, R3, Y, Z, m, and n are as defined herein.
    Type: Grant
    Filed: December 2, 2004
    Date of Patent: March 25, 2008
    Assignee: Genesoft Pharmaceuticals, Inc.
    Inventors: Roland W. Bürli, Jacob Kaizerman, Peter Jones
  • Patent number: 7329765
    Abstract: Benzothiophene compounds such as are DNA binding compounds exhibiting antibacterial activity.
    Type: Grant
    Filed: November 30, 2004
    Date of Patent: February 12, 2008
    Assignee: GeneSoft Pharmaceuticals, Inc.
    Inventors: Roland W. Burli, Eldon E. Baird, Matthew J. Taylor, Jacob A. Kaizerman, Wenhao Hu
  • Patent number: 7265129
    Abstract: Compounds represented by the formula (I), where R1, R2, R3, R4, R5, and Q are as defined herein, exhibit activity against infectious pathogens
    Type: Grant
    Filed: October 24, 2003
    Date of Patent: September 4, 2007
    Assignee: Genesoft Pharmaceuticals, Inc.
    Inventors: Peter Jones, Roland W. Burli, Chun Jiang, Dustin L. McMinn
  • Publication number: 20070105135
    Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.
    Type: Application
    Filed: July 14, 2006
    Publication date: May 10, 2007
    Applicants: GeneSoft Pharmaceuticals, Inc., Genesoft, Inc.
    Inventors: Yigong Ge, Matthew Taylor, Eldon Baird, Heinz Moser, Roland Burli
  • Publication number: 20060287247
    Abstract: Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds.
    Type: Application
    Filed: June 2, 2006
    Publication date: December 21, 2006
    Applicant: GeneSoft Pharmaceuticals, Inc.
    Inventors: Yigong Ge, Matthew Taylor, Eldon Baird, Roland Burli, Jacob Kaizerman, Amanda Martin, Brie Cadman
  • Patent number: 7078536
    Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.
    Type: Grant
    Filed: October 22, 2002
    Date of Patent: July 18, 2006
    Assignee: Genesoft Pharmaceuticals, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Heinz E. Moser, Roland W. Bürli
  • Publication number: 20060148845
    Abstract: Compounds represented by the formula (I), where R1, R2, R3, R4, R5, and Q are as defined herein, exhibit activity against infectious pathogens.
    Type: Application
    Filed: October 24, 2003
    Publication date: July 6, 2006
    Applicant: Genesoft Pharmaceuticals, Inc.
    Inventors: Peter Jones, Roland Burli, Chun Jiang, Dustin McMinn
  • Publication number: 20060128747
    Abstract: Aromatic compounds exemplified by exhibit antimicrobial activity.
    Type: Application
    Filed: August 1, 2003
    Publication date: June 15, 2006
    Applicant: GENESOFT PHARMACEUTICALS,INC.
    Inventors: Roland Burli, Eldon Baird, Jacob Kaizerman, Dustin McMinn
  • Publication number: 20060116326
    Abstract: Benzothiophene compounds such as are DNA binding compounds exhibiting antibacterial activity.
    Type: Application
    Filed: November 30, 2004
    Publication date: June 1, 2006
    Applicant: GeneSoft Pharmaceuticals, Inc.
    Inventors: Roland Burli, Eldon Baird, Matthew Taylor, Jacob Kaizerman, Wenhao Hu
  • Publication number: 20060069034
    Abstract: Antipathogenic benzamide compounds having the formula wherein at least one of the R1 groups is F, Cl, CN or CF3 and R2, R3, Y, Z, m, and n are as defined herein.
    Type: Application
    Filed: December 2, 2004
    Publication date: March 30, 2006
    Applicant: GeneSoft Pharmaceuticals, Inc.
    Inventors: Roland Burli, Jacob Kaizerman, Peter Jones
  • Patent number: 6825228
    Abstract: Benzothiophene compounds such as are DNA binding compounds exhibiting antibacterial activity.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: November 30, 2004
    Assignee: Genesoft Pharmaceuticals, Inc.
    Inventors: Roland W. Bürli, Eldon E. Baird, Matthew J. Taylor, Jacob A. Kaizerman, Wenhao Hu
  • Patent number: 6777425
    Abstract: Isoquinoline compounds having the formula where R1, R2, Y, m, n, and Z are as defined herein, bind to the minor groove of DNA and have antifungal and antibacterial activity.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: August 17, 2004
    Assignee: Genesoft Pharmaceuticals, Inc.
    Inventors: Roland W. Bürli, Peter Jones, Jacob A. Kaizerman, Wenhao Hu
  • Patent number: 6716866
    Abstract: Aryl-benzimidazole compounds according to the formula where Ar1, R1, R2, Y, W, and N are as defined herein, bind to DNA and have antibacterial activity.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: April 6, 2004
    Assignee: GeneSoft Pharmaceuticals, Inc.
    Inventors: Dustin L. McMinn, Roland W. Bürli, Jacob Kaizerman, Eldon E. Baird, Matthew J. Taylor