Abstract: Disclosed are mutants of galactosyltransferases that can catalyze formation of oligosaccharides in the presence of magnesium; mutants of galactosyltransferases having altered donor and acceptor specificity which can catalyze formation of oligosaccharides in the presence of magnesium; methods and compositions that can be used to synthesize oligosaccharides; methods for increasing the immunogenicity of an antigen; and methods to stabilize platelets.
Type:
Application
Filed:
December 6, 2004
Publication date:
August 21, 2008
Applicant:
Goverment of the US, as represented by the Secretary, Department of Health and Human Services
Inventors:
Pradman Qasba, Elizabeth Boeggeman, Boopathy Ramakrishnan