Patents Assigned to Hamilton Bonaduz AG
  • Publication number: 20190247844
    Abstract: A permanent-magnet piston subassembly (10) for a pipetting apparatus, the piston subassembly (10) extending along a piston axis (K) and comprising a plurality of permanent-magnet arrangements (14a to 14m) that are arranged one behind another along the piston axis (K) with alternatingly opposite polarization directions in such a way that for each two permanent-magnet arrangements (14i, 14j) directly successive along the piston axis, it is the case that magnetic poles located closest to one another along the piston axis (K), of different successive permanent-magnetic arrangements (14a to 14m), are like poles, is characterized in that the piston subassembly (10) encompasses a sheath tube (12), extending along the piston axis (K) constituting a tube axis (H), in which the plurality of permanent-magnet arrangements (14a to 14m) are received.
    Type: Application
    Filed: October 11, 2017
    Publication date: August 15, 2019
    Applicant: Hamilton Bonaduz AG
    Inventors: Hans-Peter Romer, Heidi Cattaneo
  • Publication number: 20190226010
    Abstract: A sample handling system and a process for the handling of chemical or biological samples is provided. The system includes a dosing device with a receiving plate configured in an essentially horizontal position in a plane defined by a first and a second axis. The dosing device has at least one working arm that is movable. The pipetting mechanism includes at least one pipetting channel that is movable and has a pipette tip mounted or mountable thereon. The system further includes at least one thermal cycler provided in the area of the receiving plate. The thermal cycler is configured on the receiving plate in such a way that the pipetting mechanism is movable in a position above the sample vessels in the thermal cycler, in a setting that allows a pipetting step to be carried out into the sample vessels in the thermal cycler by the pipetting mechanism in the position above the sample vessels in the thermal cycler.
    Type: Application
    Filed: April 2, 2019
    Publication date: July 25, 2019
    Applicant: HAMILTON Bonaduz AG
    Inventors: Martin GAJEWSKI, Mario ARANGIO
  • Patent number: 10294522
    Abstract: A sample handling system and a process for the handling of chemical or biological samples is provided. The system includes a dosing device with a receiving plate configured in an essentially horizontal position in a plane defined by a first and a second axis. The dosing device has at least one working arm that is movable. The pipetting mechanism includes at least one pipetting channel that is movable and has a pipette tip mounted or mountable thereon. The system further includes at least one thermal cycler provided in the area of the receiving plate. The thermal cycler is configured on the receiving plate in such a way that the pipetting mechanism is movable in a position above the sample vessels in the thermal cycler, in a setting that allows a pipetting step to be carried out into the sample vessels in the thermal cycler by the pipetting mechanism in the position above the sample vessels in the thermal cycler.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: May 21, 2019
    Assignee: HAMILTON BONADUZ AG
    Inventors: Martin Gajewski, Mario Arangio
  • Patent number: 10247692
    Abstract: A reference electrode assembly for an electrochemical sensor, in particular for a potentiometric sensor, comprising a reference half-cell space having a reference electrode provided therein, the reference half-space comprising a storage space in which a reference electrolyte is provided at any rate in a storage state of the reference electrode assembly, the reference half-cell space further comprising a lock space that is permeable at any rate with respect to the passage of reference electrolyte into an environment of the reference half-cell space, the storage space, in the storage state of the reference electrode assembly, being separated from the lock space with respect to the passage of reference electrolyte, the reference electrode assembly being designed such that a connection permeable for the passage of reference electrolyte from the storage space to the lock space can be created between the storage space and the lock space in order to transfer the reference electrode assembly from the storage state to
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: April 2, 2019
    Assignee: HAMILTON BONADUZ AG
    Inventors: Dirk Schönfuss, Philipp Arquint, Clara Caminada-Cavelier
  • Publication number: 20190079069
    Abstract: A method is provided for calibrating impedance-spectroscopic biomass sensors that are embodied to detect information regarding the quantity and/or size of living cells in a biomass by means of an electric field having a periodically changing field direction A calibration suspension encompasses an electrically conductive viscously flowable or viscoelastic carrier substance and electrically conductive solid particles and/or solid semiconductor particles received therein. An electric field is generated having a periodically changing field direction, which acts on the calibration suspension. At least one permittivity value is detected, respectively representing a permittivity of the calibration suspension, in a context of at least two electric fields having different field direction change frequencies. A difference value is ascertained that represents a difference between the detected permittivity values. The difference value is compared with a reference value associated with the calibration suspension.
    Type: Application
    Filed: March 1, 2017
    Publication date: March 14, 2019
    Applicant: Hamilton Bonaduz AG
    Inventors: Marlene Frank, Philipp Arquint, Theo Gaupp
  • Publication number: 20190032002
    Abstract: A cell separation apparatus a container for reception of a cell suspension and a conduit connected to the container for the conveyance of cell suspension out of the container. The conduit extends along a notional conduit path passing centrally through the conduit, the conduit path defining in the conduit an axial direction proceeding along the conduit path, a radial direction orthogonal to the conduit path, and a circumferential direction proceeding around the conduit path. A segment of the conduit constitutes a turbulent flow segment including a flow configuration. The flow configuration includes at least two axial configuration segments located axially behind one another to accelerate a cell suspension.
    Type: Application
    Filed: February 9, 2017
    Publication date: January 31, 2019
    Applicants: Hamilton Bonaduz AG, Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V.
    Inventors: Tom Kissling, Jens Grosch, Thomas Zumstein, Andrea Traube, Carsten Etzold, Tobias Seiler
  • Patent number: 10161871
    Abstract: The invention relates to a sensing unit (1) comprising a housing (2) that has a first housing opening which can be oriented towards a medium (M) to be analyzed, and a second housing opening on which at least one means for detachably rigidly connecting to a sensor shaft or sensor housing are arranged, or may be arranged, on the inner and/or outer side; at least one sensor element (3) that is arranged in the housing (2) and comprises indicators and, optionally, indicator protectors, said sensor element (3) having a first side facing the first housing opening and a second side lying opposite the first housing opening; and at least one protector element (4) which is arranged in the region of the first housing opening between the at least one sensor element (3) and the medium (M) which surrounds the sensing unit (1), particularly in the region of said housing opening, such that the sensor element (3) does not come into direct contact with the medium (M).
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: December 25, 2018
    Assignee: HAMILTON BONADUZ AG
    Inventors: Dirk Schoenfuss, Claudius-Michael Ortega Schulte
  • Patent number: 10119983
    Abstract: Described herein are sample manipulation devices, for removing lids from and/or for placing lids onto sample containers. Such devices include a sample unit including a sample carrier receptacle for receiving at least one sample carrier for holding one or more sample containers, and a manipulation unit having at least one manipulation tool, where the sample unit and the manipulation unit are movable relative to each other along a movement direction. The sample unit is also movable between a first orientation in which a longitudinal direction of a sample carrier in the sample carrier receptacle is parallel to the movement direction between sample unit and manipulation unit, and a second orientation in which a transverse direction, which is orthogonal to the longitudinal direction, of a sample carrier in the sample carrier receptacle is parallel to the movement direction between sample unit and manipulation unit.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: November 6, 2018
    Assignee: HAMILTON BONADUZ AG
    Inventors: Peter Hoffmann, Martin Frey, Beat Zahner, Petra Tappe
  • Patent number: 10113887
    Abstract: A scale and related method for a length-measuring system for recording the absolute values of angles or distances. The scale includes a printed circuit board, at least one track for identifying length information or angle information and a coding for identifying the scale. The coding has at least one coding element comprising at least two electrodes and a conductive connection between the electrodes on an insulator substrate. The electrical connection is configured to be irreversibly destroyed when an electrical current is applied.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: October 30, 2018
    Assignee: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Manuel Altmeyer, Martin Rupp
  • Patent number: 10093893
    Abstract: The invention relates to a liquid supply interface (62, 62?, 62?, 62??) for a cell culture system for supplying cell cultures found in different cell culture containers (10, 10?, 10?) with a nutrient medium, wherein the liquid supply interface (62, 62?, 62?, 62??) comprises: a housing (68) defining a flow area (72); a first connection formation (76) for the liquid-transferring connection of a first fluid line (84) to the housing (68); a second connection formation (78) formed separately from the first for the liquid-transferring connection of a second fluid line (88) to the housing (68); a third connection formation (80) formed separately from the first two for the liquid-transferring connection of the housing (68) to a third fluid line; a coupling formation (64, 66) formed separately from the connection formations (76, 78, 80), which is formed for the producible and detachable liquid-transferring coupling contact according to the operation, with a corresponding counter-coupling formation (38, 40) of a cell c
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: October 9, 2018
    Assignee: Hamilton Bonaduz AG
    Inventors: Thomas Jäger, Dirk Schlenker, Nabih Othman, Oliver Kühne
  • Patent number: 10078072
    Abstract: A sample dispenser for an analysis device, in particular for an analysis device working according to the principle of liquid chromatography, in particular high pressure liquid chromatography, or gas chromatography, comprising a sample intake for receiving a sample to be analyzed, an inlet through which an eluent can be supplied, an outlet, and an injection valve arrangement, which can be switched at least from an intake position to an injection position, wherein, at least in the intake position and in the injection position, the inlet is in fluid connection with the outlet to deliver the eluent—if applicable, having the sample added thereto—at least partly to the outlet, wherein, in the intake position, the sample intake is separated from the eluent in a fluid-tight manner, and wherein, in the injection position, the sample in the sample intake can combine with the eluent, wherein the sample dispenser is configured as a disposable component.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: September 18, 2018
    Assignee: HAMILTON BONADUZ AG
    Inventors: Klaus Leckebusch, Tino Otte
  • Patent number: 10050507
    Abstract: A linear motor, comprises at least one stator device (14) with a plurality of permanent magnets (18, 18-1, 18-2) of different polarity and with at least one carrier rail (24), and at least one rotor device (12) with at least three electrical coils (44) and with at least one supporting means (26), which can be or which is supported on the carrier rail (24) of the stator device (14), wherein the rotor device (12) and the stator device (14) are moveable to and fro with respect to each other along a movement direction (FR) defined by the carrier rail (24) by interaction of magnetic fields of the permanent magnets (18, 18-1, 18-2) with the magnetic fields of the coils (44), through which current flows if required, wherein the stator device (14) is formed from at least one stator module (16-1, 16-2), wherein the stator module (16-1, 16-2) is configured such that a stator device (16) with two or more consecutively arranged stator modules (16-1, 16-2) can be formed, and wherein at the stator module (16-1, 16-2) at le
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: August 14, 2018
    Assignee: Hamilton Bonaduz AG
    Inventors: Meinrad Franz Hofstetter, Eduard Nawrocki, Hanspeter Romer, Vinzenz Kirste
  • Patent number: 9952187
    Abstract: The invention relates to an optical sensor element, comprising indicators, selected from luminescence-active means that are of the same type or different, and indicator protectors, and to a sensor, comprising at least one such sensor element, an energy source that excites the luminescence emission of the indicators, and a detector unit, wherein the sensor element or sensor is suitable for detecting molecular oxygen in a gaseous or liquid medium and/or for determining the molecular oxygen content of a gaseous or liquid medium and at least one layer of the sensor element bearing the indicator protectors is designed in such a way that the diffusion rate of the molecular oxygen formed on the indicator protectors by means of the reduction of strong oxidants back into the medium is greater than the diffusion rate of molecular oxygen from the medium in the direction of the at-least-one layer bearing the indicator molecules.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: April 24, 2018
    Assignee: Hamilton Bonaduz AG
    Inventors: Dirk Schoenfuss, Claudius-Michael Ortega Schulte
  • Publication number: 20180053547
    Abstract: An autonomous device for detecting characteristics of a medium to be measured is disclosed. The device includes a sensor, a first microcontroller and a second microcontroller. The first microcontroller has a memory which is not resistant against gamma radiation during the sterilization of the device and the second microcontroller has a memory which is resistant against gamma radiation during the sterilization of the device.
    Type: Application
    Filed: July 12, 2017
    Publication date: February 22, 2018
    Applicants: HAMILTON Bonaduz AG, smartINST SAS
    Inventors: Frederic Juillerat, Yoann Gasteuil
  • Patent number: 9810577
    Abstract: A device for measuring a periodic signal includes: a first control unit for generating an electrical input signal (V1) of the period T; a light source for generating an optical input signal directed to an object being measured from the electrical input signal (V1); an optical receiver for detecting and converting the signal reflected from the object being measured, the signal corresponding to the optical input signal altered in terms of phase and amplitude, into an electrical measurement signal (V2); and a plurality of measurement channels connected in parallel between the optical receiver and a second control unit, each measurement channel being connected in series to a switching element, a filter element, and an analog-to-digital converter, wherein the second control unit is suitable for evaluating the measurement signals from the plurality of measurement channels, and in which the electrical measurement signal (V2) is applied to each of the plurality of measurement channels, the first control unit is conne
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: November 7, 2017
    Assignee: Hamilton Bonaduz AG
    Inventors: Bernd Offenbeck, Philipp Arquint
  • Patent number: 9803789
    Abstract: The present invention relates to a coupling formation of a pipetting channel of a pipetting device for coupling of an implement, for instance a pipette tip, or a laboratory instrument, laboratory tool or the like, thereto, wherein the coupling formation surrounds a pipetting channel section which extends along a pipetting channel axis which defines an axial direction, wherein the coupling formation additionally has, at its free longitudinal end, a pressure-imparting orifice into which the pipetting channel section opens and has, at its radially outer surface which surrounds the pipetting channel axis and extends principally in axial direction and in peripheral direction about the pipetting channel axis relative to the pipetting channel axis, a coupling projection which yields in the radial direction, which is characterized in that the coupling projection is provided so as to be essentially undeformable but radially movable on a spring arrangement which is elastic in radial direction.
    Type: Grant
    Filed: July 23, 2013
    Date of Patent: October 31, 2017
    Assignee: HAMILTON BONADUZ AG
    Inventors: Andreas Städler, Torsten Peetz
  • Patent number: 9766203
    Abstract: The potentiometric sensor element comprises a measuring element and a shield housing permanently bonded to the measuring element, in which housing an electronic sensor unit is accommodated and which is sealed off against external influences. The electronic sensor unit is connected to a contactless interface adapted to exchange energy and signals with a corresponding contactless interface in an electronic base unit. The shield housing comprises an outer sleeve and an inner sleeve, accommodated within the outer sleeve, wherein the electronic sensor unit is accommodated in the inner sleeve and is surrounded there by a first casting compound. The filled inner sleeve is in turn bonded permanently to the outer sleeve by means of a second casting compound, which is different from the first casting compound.
    Type: Grant
    Filed: September 9, 2013
    Date of Patent: September 19, 2017
    Assignee: Hamilton Bonaduz AG
    Inventors: Philipp Arquint, Fabio Sovrano, Karl Furger
  • Patent number: 9764870
    Abstract: A tool device for the automated opening of flip tubes including an actuating plunger which is provided and configured to move the actuating portion at least in open direction and thereby to exert an opening moment on the lid portion, and wherein the device further includes a damping means which is configured to exert a damping moment on the container lid at least during a period of the actuation of the actuating portion by the actuating plunger, which damping moment is less in amount and is in an opposite direction compared to the opening moment.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: September 19, 2017
    Assignee: Hamilton Bonaduz AG
    Inventors: Walter Kubler, Rainer Beckbissinger, Urs Muller
  • Publication number: 20170227562
    Abstract: The invention relates to a sample processing system and method for processing biological samples, comprising a sample processing device having: a receiving plate, which is arranged substantially horizontally in a plane; a first and second working arm, which can move relative to the receiving plate and extend substantially parallel to each other in a second direction (Y) over the receiving plate; at least one pipetting device mounted on the first working arm, which is movable in the second direction (Y) and in a third direction (Z) orthogonal in relation to the first and second direction (X, Y); at least one gripping device, mounted on the second working arm, with grippers that can be rotated around a gripper axis of rotation (GA) parallel to the third direction (Z); and a control device for controlling the pipetting device and the gripping device.
    Type: Application
    Filed: April 28, 2017
    Publication date: August 10, 2017
    Applicant: HAMILTON BONADUZ AG
    Inventor: Nando GIOVANOLI
  • Patent number: 9689884
    Abstract: A metering apparatus includes a base and a vertical support coupled to the base and extending upwardly from the base. The metering apparatus also includes a transverse support coupled to the vertical support, vertically spaced from the base. The metering apparatus also includes a pipetting device coupled to the transverse support, the pipetting device including at least one pipetting channel configured to attach to a pipetting tip. The metering apparatus also includes a disposal container configured to receive used pipetting tips from the pipetting channel, detachably coupled to the vertical support. The pipetting device is movable in first, second, and third directions substantially orthogonal to each other. The disposal container is moveable in one of the first, second, and third directions.
    Type: Grant
    Filed: April 14, 2013
    Date of Patent: June 27, 2017
    Assignee: Hamilton Bonaduz AG
    Inventors: Torsten Peetz, Andreas Städler