Patents Assigned to Hamilton Bonaduz AG
  • Publication number: 20140193826
    Abstract: The invention concerns a sample handling system and a process for the handling of chemical or biological samples, particularly body fluids such as blood, saliva, secretions, etc.
    Type: Application
    Filed: January 8, 2014
    Publication date: July 10, 2014
    Applicant: HAMILTON BONADUZ AG
    Inventors: Martin GAJEWSKI, Mario ARANGIO
  • Patent number: 8753715
    Abstract: Processes for hydrophobically coating a pipette tip by wetting at least regions of the outside and inside of the pipette by with a wetting solution are disclosed. Such a process may include coupling the pipette tip to a fluid pressure source having variable fluid pressure, immersing the coupled pipette tip in the wetting solution, aspirating wetting solution into the pipette tip, dispensing the aspirated wetting solution, and evaporating solvent contained in the wetting solution.
    Type: Grant
    Filed: July 12, 2011
    Date of Patent: June 17, 2014
    Assignee: Hamilton Bonaduz AG
    Inventors: Vinzenz Kirste, Renato Nay, Rainer Beckbissinger
  • Publication number: 20140102275
    Abstract: The invention relates to a punching device for processing dried samples applied to a sample card, in particular liquids containing DNA, such as blood, saliva and the like, comprising at least one punching means (110) with a punch and a lower die, wherein the punch is movable between a resting position at a distance from the lower die and a punching position closer to the lower die. The punching means (110) has a receiving opening into which a sample card can be introduced by means of a movable gripping unit (300) of the punching device (10) and can be positioned in relation to the punching means (110), and a punching drive (14) which can be coupled or is coupled to the punch of the punching means (110) and which drives the punch between the resting position and the punching position. According to the invention, it is proposed that the punching means (110) has a structure which is separate from the punching device (10) and on which the punch and the lower die are arranged.
    Type: Application
    Filed: April 29, 2012
    Publication date: April 17, 2014
    Applicant: HAMILTON BONADUZ AG
    Inventors: Nando Giovanoli, Reto Menzi
  • Patent number: 8673624
    Abstract: The present invention relates to a calibratable sensor unit for a reaction vessel, such as for example a fermenter (48), in particular a disposable fermenter, comprising at least one sensor device (14) to be calibrated and at least one compartment (26, 28, 30) containing a calibrating agent, the at least one sensor device and the at least one compartment (26, 28, 30) being accommodated movably relative to one another in a housing (12) that is connected to or can be connected to the reaction vessel (48), wherein the calibrating unit (10) is arranged to calibrate the at least one sensor device (14) by contact with the calibrating agent before chemical and/or physical parameters of a measurement substance are measured with the at least one sensor device (14). According to the invention it is proposed that the sensor device (10) is configured in such a way that the relative movement between the at least one sensor device (14) and the at least one compartment (26, 28, 30) can be carried out irreversibly.
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: March 18, 2014
    Assignee: Hamilton Bonaduz AG
    Inventors: Andreas Loebbert, Dirk Schoenfuss
  • Publication number: 20140056762
    Abstract: The invention relates to a punching device for processing samples, in particular dried samples, applied to a sample card, preferably liquids containing DNA, such as blood, saliva and the like, comprising at least one punching means with a punch and a lower die, the punch being movable between a resting position at a distance from the lower die and a punching position closer to the lower die.
    Type: Application
    Filed: April 29, 2012
    Publication date: February 27, 2014
    Applicant: HAMILTON BONADUZ AG
    Inventors: Nando Giovanoli, Reto Menzi
  • Patent number: 8656792
    Abstract: A pipette device including a metering liquid receptacle designed to be filled, at least in part, with working fluid and which has a pipette opening as a first tapering of cross-section of flow, a pressure change device which is designed to change the pressure of the working fluid in the metering liquid receptacle, and a throttle point in a pipette duct designed to be filled with working fluid as a further tapering of cross-section of flow. The throttle point is arranged fluid-mechanically between the metering liquid receptacle and the pressure change device and is dimensioned in such a way that a ratio of a flow resistance of the pipette opening for dispensed metering liquid to a flow resistance of the throttle point for working fluid, which flows through the throttle point when the metering fluid is dispensed, is less than 0.5.
    Type: Grant
    Filed: July 26, 2011
    Date of Patent: February 25, 2014
    Assignee: Hamilton Bonaduz AG
    Inventors: Vinzenz Kirste, Helmut Knapp, Urs Lendenmann, Noa Schmid, Tobias Seiler, Fabian Winter
  • Publication number: 20140050637
    Abstract: The invention relates to a punching device for processing samples, in particular dried samples, applied to a sample card, preferably liquids containing DNA, such as blood, saliva and the like, comprising at least one punching means with a punch and a lower die, wherein the punch is movable between a resting position at a distance from the lower die and a punching position closer to the lower die. The punching means has a receiving opening, into which a sample card from a sample card container can be introduced by means of a movable gripping unit (300) of the punching device and can be positioned in relation to the punching means, and a punching drive, which can be coupled or is coupled to the punch of the punching means and which drives the punch between the resting position and the punching position.
    Type: Application
    Filed: April 29, 2012
    Publication date: February 20, 2014
    Applicant: HAMILTON BONADUZ AG
    Inventors: Nando Giovanoli, Reto Menzi
  • Publication number: 20140047962
    Abstract: The invention relates to a punching device for processing samples, in particular dried samples, applied to a sample card, preferably liquids containing DNA, such as blood, saliva and the like, comprising at least one punching means (110) with a punch and a lower die, wherein the punch is movable between a resting position at a distance from the lower die and a punching position closer to the lower die, and wherein the punching means (110) has a receiving opening, into which a sample card can be introduced by means of a movable gripping unit (300) of the punching device (10) and can be positioned in relation to the punching means (110), and a punching drive (14), which can be coupled or is coupled to the punch of the punching means (110) and which drives the punch between the resting position and the punching position.
    Type: Application
    Filed: April 29, 2012
    Publication date: February 20, 2014
    Applicant: HAMILTON BONADUZ AG
    Inventors: Nando Giovanoli, Reto Menzi
  • Patent number: 8623298
    Abstract: A syringe comprises a syringe body (12) having an axial inner recess (14) extending in the direction of a longitudinal axis of the syringe body (L), a piston (16) being guided in an axially moveable manner in said inner recess and contributing to the delimitation of a fluid-receiving volume together with a section of a wall (14a) radially delimiting the inner recess (14), and having a needle (24) that can be or is connected to a longitudinal end (12a) of the syringe body (12), wherein the needle (24) has a coupling geometry (28) at the longitudinal end (24a) thereof that is closer to the syringe body, wherein the needle (24) can be connected by said coupling geometry to a counter coupling geometry (30) of the syringe body (12), wherein the geometry composed of the coupling geometry (28) and counter coupling geometry (30) comprises an insertion section (32), which in the assembled state of the syringe (10) is received in a coupling recess (34) of the respectively other geometry, and wherein furthermore safety
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: January 7, 2014
    Assignee: Hamilton Bonaduz AG
    Inventor: Klaus Leckebusch
  • Publication number: 20140001215
    Abstract: The invention relates to a radial sliding seal component, particularly for use in metering devices, such as syringes and pipetting piston-cylinder arrangements, comprising a sealing component working together with at least one pretensioning component , wherein the sealing component comprises a sealing segment extending in the axial direction and in the circumferential direction, on which a sealing surface facing in a first radial direction for sealing and sliding contact in at least the axial direction is formed on a working surface extending in the axial direction and in the circumferential direction, and on which a pretensioning surface extending in a second radial direction opposite to the first is formed for engaging with the pretensioning component for transferring the radial pretensioning force, wherein the pretensioning component comprises a spring carrier and a plurality of separately formed radial spring segments compliantly supported at least in the radial direction on the spring carrier.
    Type: Application
    Filed: August 30, 2013
    Publication date: January 2, 2014
    Applicant: HAMILTON BONADUZ AG
    Inventor: Klaus LECKEBUSCH
  • Publication number: 20130341549
    Abstract: The invention relates to a radial sliding seal component, particularly for use in metering devices, such as syringes and pipetting piston-cylinder arrangements, comprising a sealing component working together with at least one pretensioning component, wherein the sealing component comprises a sealing segment extending in the axial direction and in the circumferential direction, on which a sealing surface facing in a first radial direction for sealing and sliding contact in at least the axial direction is formed on a working surface extending in the axial direction and in the circumferential direction, and on which a pretensioning surface extending in a second radial direction opposite to the first is formed for engaging with the pretensioning component for transferring the radial pretensioning force, wherein the pretensioning component comprises a spring carrier and a plurality of separately formed radial spring segments compliantly supported at least in the radial direction on the spring carrier.
    Type: Application
    Filed: August 30, 2013
    Publication date: December 26, 2013
    Applicant: Hamilton Bonaduz AG
    Inventor: Klaus LECKEBUSCH
  • Publication number: 20130293706
    Abstract: The invention relates to a method for optically analyzing a sample liquid (34) contained in a sample container (24a-h), wherein the sample liquid (34) contains at least one substance (40) in at least partially dissolved form, comprising the following steps: providing at least one sample container (24a-h) filled with sample liquid (34); illuminating the at least one sample container (24a-h) by means of a light source (18a-h); and recording an image of an identification pattern (32a-h) associated with the at least one sample container (24a-h) by means of an image recording device (22) that produces image data, wherein the optical path (OP) is selected in such a way that the sample liquid (34) contained in the at least one sample container (24a-h) lies at least partially between the image recording plane (36) of the image recording device (22) and the identification pattern (32a-h). The invention further relates to an analysis device for carrying out the method.
    Type: Application
    Filed: January 25, 2012
    Publication date: November 7, 2013
    Applicant: HAMILTON BONADUZ AG
    Inventors: Daniela Pison, Friedrich Neuhaeusser-Wespy, Stefan Gluekler, Johann Seeber, Urs Gredig, Michael Spoerri
  • Publication number: 20130277872
    Abstract: The present invention relates to a process for the automated production of active substance beads having a gel-like carrier material, preferably a biopolymer, such as agarose, and having embedded in the carrier material a biologically active material, such as an active substance and/or a material which generates an active substance, comprising the following steps: a) provision of a flowable, solidifiable mixture comprising the carrier material and the biologically active material, b) solidification of a core bead by introducing a predetermined amount of the flowable mixture into a fluid bath, preferably a liquid bath, particularly preferably an oil bath, c) removal of the core bead from the fluid bath, wherein for carrying out step c), a bead contact surface of a bead receiving tool is used, and for this purpose step c) comprises either the following sub-step ca1) or the following sub-step cb1): ca1) creation of a locating engagement between the core bead and a preferably concave bead reduced-pressure contact
    Type: Application
    Filed: September 2, 2011
    Publication date: October 24, 2013
    Applicants: Hamilton Bonaduz AG, HAMILTON COMPANY
    Inventors: Craig Vincze, Lori Jensen, Mareen Schmökel, Frieder Neuhäusser-Wespy, Carsten Etzold
  • Patent number: 8557197
    Abstract: The invention relates to a radial sliding seal component (10), particularly for use in metering devices, such as syringes, pipetting piston-cylinder arrangements, and the like, comprising a sealing component (12) working together with at least one pretensioning component (14), wherein the sealing component (12) comprises a sealing segment (16) extending in the axial direction and in the circumferential direction, preferably running in the circumferential direction, on which a sealing surface (18) facing in a first radial direction for sealing and sliding contact in at least the axial direction is formed on a working surface extending in the axial direction and in the circumferential direction, preferably running in the circumferential direction, and on which a pretensioning surface (20) extending in a second radial direction opposite to the first is formed for engaging with the pretensioning component (14) for transferring the radial pretensioning force, wherein the pretensioning component (14) comprises a sp
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: October 15, 2013
    Assignee: Hamilton Bonaduz AG
    Inventor: Klaus Leckebusch
  • Publication number: 20130243669
    Abstract: A sample container comprises a first container and a second container enclosing the first container, the containers capable of being brought into a storage position to form a collecting chamber therebetween having a first, smaller volume, and into an analysis position, in which the collecting chamber has a second, larger volume, wherein a fixing means is provided on the first container, which can be brought into fixing engagement with a mating fixing means provided on the second container such that relative motion of the containers is made more difficult in at least one relative motion direction and/or wherein a locking means is provided on the first container, which locking means can be brought into locking engagement with a mating locking means provided on the second container such that relative motion of the two containers is made more difficult in at least one relative motion direction.
    Type: Application
    Filed: November 24, 2011
    Publication date: September 19, 2013
    Applicant: HAMILTON BONADUZ AG
    Inventors: Laurent Baron, Armin Panzer, Flurin Gallmann
  • Publication number: 20130233096
    Abstract: The invention relates to a pipetting device, comprising at least two pipetting channels (50, 50?), which extend along a channel axis (K) and which each can be adjusted along the channel axis (K), wherein the pipetting device (10) has a displacement drive, by means of which each pipetting channel (50, 50?) can be displaced independently of the other pipetting channel (50, 50?) along a displacement axis (V) orthogonal to the channel axis (K) regardless of an adjustment along the channel axis (K), wherein the displacement drive comprises a linear motor, the stator of which has at least two magnet arrangements (32, 42), which comprise a row of magnets (36) on a magnet carrier (34, 44), said magnets being consecutive along the displacement axis (V) and being arranged differently with regard to the polarity (P1, P2) thereof, and the armature of which (at 38, at 38?); has at least one conductor loop arrangement (38), which comprises at least one set of three conductor loops (72, 74, 76) that are consecutive along th
    Type: Application
    Filed: December 23, 2011
    Publication date: September 12, 2013
    Applicant: HAMILTON BONADUZ AG
    Inventors: Andreas Schlegel, Hanspeter Romer
  • Publication number: 20130200886
    Abstract: The present invention provides a position detecting device for detecting a positional relationship between a first component (10) and a second component (12), comprising a marking arrangement (14) which is provided on the first component (10) and has an absolute track (18) and an incremental track (20), the absolute track (18) having a plurality of absolute markings (22) from which a binary absolute code sequence (B) can be read, and the incremental track (20) having a plurality of incremental markings (24) which are associated with the absolute markings (22) and from which an alternating incremental sequence (I) can be read, and a sensor arrangement (16) which is provided on the second component (12) and is configured to scan the absolute markings (22) and the incremental markings (24; 24), wherein the absolute code sequence (B) is formed from a first and a second De Bruijn sequence (B1, B2) of order N which follow one another, the second De Bruijn sequence (B2) being a cyclic shift of the first De Bruijn se
    Type: Application
    Filed: April 20, 2010
    Publication date: August 8, 2013
    Applicant: HAMILTON BONADUZ AG
    Inventors: Vinzenz Kirste, Claudio Gian Köppel
  • Publication number: 20130118118
    Abstract: A tool device for the automated opening of flip tubes including an actuating plunger which is provided and configured to move the actuating portion at least in open direction and thereby to exert an opening moment on the lid portion, and wherein the device further includes a damping means which is configured to exert a damping moment on the container lid at least during a period of the actuation of the actuating portion by the actuating plunger, which damping moment is less in amount and is in an opposite direction compared to the opening moment.
    Type: Application
    Filed: May 18, 2011
    Publication date: May 16, 2013
    Applicant: HAMILTON BONADUZ AG
    Inventors: Walter Kubler, Rainer Beckbissinger, Urs Muller
  • Publication number: 20130001242
    Abstract: The invention relates to a metering device (10; 10a; 10b) comprising a guide tube (20; 20a; 20b), a piston (24; 24a; 24b) inserted displaceably in the guide tube (20; 20a; 20b), an actuating assembly (40; 40a; 42) for exerting a force on the piston (24; 24a; 24b) in order to displace the piston (24; 24a; 24b) in the guide tube (20; 20a; 20b), and a chamber (28, 30) for receiving a medium to be metered (34), said medium to be metered (34) can be aspirated or dispensed according to a displacement of the piston (24; 24a; 24b), the actuating assembly (40; 40a; 42) being equipped for a magnetic interaction with the piston (24; 24a; 24b).
    Type: Application
    Filed: January 5, 2011
    Publication date: January 3, 2013
    Applicant: HAMILTON BONADUZ AG
    Inventors: Meinrad Hofstetter, Vinzenz Kirste
  • Patent number: 8245586
    Abstract: For aspiration and dispensation of a metering fluid, a pipetting apparatus comprises a work fluid which differs from the former, the work fluid being accommodated in a work space with a variable volume which extends along a channel axis and, with reference to the latter, is formed by a piston-cylinder system at least along an axial section of the channel axis, having a cylinder which delimits the work space along a cylinder section in the radial direction and a piston which delimits the work space in a first axial direction, the cylinder and the piston being arranged so that they can move with respect to each other such that the piston-cylinder system has an axial longitudinal end region for metering, which is open for aspiration and dispensation, and an axial longitudinal end region for work which is closed by the piston, the piston being designed as an outer piston and surrounding the cylinder on the outside in the longitudinal end region for work of the piston-cylinder system.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: August 21, 2012
    Assignee: Hamilton Bonaduz AG
    Inventors: Armin Panzer, Patrick Schelling