Abstract: Luggage is disclosed that includes a main body that defines an interior compartment bounded by a top wall, a bottom wall, a front wall, a rear wall, and side walls. The front wall is hingeably connected with one of the side walls and includes a closing mechanism for sealing or unsealing the interior compartment. An accessory compartment is formed within one of the front wall, the rear wall, or one of the side walls. The accessory pocket includes a first sealable access mechanism to permit access to the accessory pocket from an exterior of the main body. It also includes a second access mechanism to permit access to the accessory pocket from the interior of the main body. Wheels are positioned along the bottom wall, and handle assembly is attached with the main body and deployable from a stowed position.