Patents Assigned to Hetero Research Foundation
  • Process for pomalidomide
    Patent number: 11053211
    Abstract: The present invention provides a novel process for the preparation of pomalidomide crystalline Form I. The present invention also provides a process for the purification of pomalidomide.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: July 6, 2021
    Assignee: HETERO RESEARCH FOUNDATION
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Matta Ramakrishna Krishna Reddy, Bandi Vamsi Krishna
  • Process for the preparation of lomitapide
    Patent number: 10934251
    Abstract: The present invention relates to a process for preparing Lomitapide or its pharmaceutically acceptable salt thereof having high purity with acceptable levels of impurities.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: March 2, 2021
    Assignee: HETERO RESEARCH FOUNDATION
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Bandi Vamsi Krishna, Jambula Mukunda Reddy
  • Process for the preparation of intermediate of dolutegravir
    Patent number: 10442769
    Abstract: The present invention provides a novel processes for preparation of methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyiridine-2-carboxylate using novel intermediates.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: October 15, 2019
    Assignee: Hetero Research Foundation
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dsari Muralidhara Reddy, Mogili Narsingam, Bandi Vamsi Krishna
  • Crystalline form of Eltrombopag free acid
    Patent number: 10336706
    Abstract: The present invention relates to crystalline form of Eltrombopag free acid and its process for preparation.
    Type: Grant
    Filed: September 2, 2015
    Date of Patent: July 2, 2019
    Assignee: HETERO RESEARCH FOUNDATION
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Jonnala Sambi Reddy, Bandi Vamsi Krishna
  • Rufinamide solid dispersion
    Patent number: 10206874
    Abstract: The present invention provides a solid dispersion of rufinamide in combination with a pharmaceutically acceptable carrier, process for its preparation and pharmaceutical compositions comprising it.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: February 19, 2019
    Assignee: Hetero Research Foundation
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Kesireddy Subash Chander Reddy, Bandi Vamsi Krishna
  • Process for the preparation of lomitapide
    Patent number: 10023526
    Abstract: The present invention relates to a process for preparing Lomitapide or its pharmaceutically acceptable salt thereof having high purity with acceptable levels of impurities.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: July 17, 2018
    Assignee: Hetero Research Foundation
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Bandi Vamsi Krishna, Jambula Mukunda Reddy
  • Pharmaceutical compositions of raltegravir, methods of preparation and methods of use therof
    Patent number: 9968607
    Abstract: Disclosed are pharmaceutical compositions comprising HIV integrase strand transfer inhibitor. More particularly, oral pharmaceutical compositions of raltegravir or its pharmaceutically acceptable salts and process for preparing and use of the same are disclosed.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: May 15, 2018
    Assignee: HETERO RESEARCH FOUNDATION
    Inventors: Bandi Parthasaradhi Reddy, Podili Khadgapathi, Goli Kamalakar Reddy
  • Process for the preparation of intermediate of dolutegravir
    Patent number: 9963430
    Abstract: The present invention provides a novel processes for preparation of methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyiridine-2-carboxylate using novel intermediates.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: May 8, 2018
    Assignee: Hetero Research Foundation
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Mogili Narsingam, Bandi Vamsi Krishna
  • PROCESS FOR THE PREPARATION OF INTERMEDIATE OF DOLUTEGRAVIR
    Publication number: 20170334858
    Abstract: The present invention provides a novel processes for preparation of methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyiridine-2-carboxylate using novel intermediates.
    Type: Application
    Filed: December 14, 2015
    Publication date: November 23, 2017
    Applicant: HETERO RESEARCH FOUNDATION
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Mogili Narsingam, Bandi Vamsi Krishna
  • Process for cabazitaxel
    Patent number: 9815806
    Abstract: The present invention provides an improved process for the preparation of 4?-acetoxy-2?-benzoyloxy-5?,20-epoxy-1?,13?-dihydroxy-7?,10?-dimethoxy-9-oxo-11-taxene (7?,10?-dimethoxy-10-deacetoxybaccatin III). The present invention also provides a novel process for the preparation of cabazitaxel.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: November 14, 2017
    Assignee: Hetero Research Foundation
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Adulla Venkat Narsimha Reddy, Bandi Vamsi Krishna
  • Process for pralatrexate
    Patent number: 9783542
    Abstract: The present invention provides a novel process for the purification of alpha-propargylhomoterephthalic acid dimethyl ester substantially free of homoterephthalic acid dimethyl ester. The present invention also provides a novel process for the purification of pralatrexate.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: October 10, 2017
    Assignee: Hetero Research Foundation
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Katham Srinivasa Reddy, Bandi Vamsi Krishna
  • Compositions of eltrombopag
    Patent number: 9770437
    Abstract: The present invention relates to compositions of eltrombopag olamine. The present invention also relates to process for preparing compositions comprising eltrombopag olamine.
    Type: Grant
    Filed: September 1, 2014
    Date of Patent: September 26, 2017
    Assignee: HETERO RESEARCH FOUNDATION
    Inventors: Bandi Parthasaradhi Reddy, Podili Khadgapathi, Nelluri Ramarao
  • NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS
    Publication number: 20170129916
    Abstract: The invention relates to novel betulinic proline substituted derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.
    Type: Application
    Filed: June 25, 2015
    Publication date: May 11, 2017
    Applicant: HETERO RESEARCH FOUNDATION
    Inventors: Bandi PARTHASARADHI REDDY, Kura RATHNAKAR REDDY, Gazula Levi DAVID KRUPADANAM, Adulla PANDURANGA REDDY, Bammidi ESWARA RAO, Ranga REDDY
  • Betulinic acid proline derivatives as HIV inhibitors
    Patent number: 9637516
    Abstract: The invention relates to novel betulinic acid derivatives and related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.
    Type: Grant
    Filed: December 26, 2013
    Date of Patent: May 2, 2017
    Assignee: HETERO RESEARCH FOUNDATION
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Lanka Vl Subrahmanyam, Gazula Levi David Krupadanam, Mukkera Venkati, Neela Sudhakar, Kallem Srinivas Reddy
  • Amorphous darunavir
    Patent number: 9624236
    Abstract: Described herein is pure amorphous darunavir, methods of making pure amorphous darunavir and pharmaceutical compositions containing amorphous darunavir and a pharmaceutically acceptable excipient.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: April 18, 2017
    Assignee: HETERO RESEARCH FOUNDATION
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Rapolu Raji Reddy, Kesireddy Subash Chander Reddy, Bandi Vamsi Krishna
  • Polymorphs of azilsartan medoxomil
    Patent number: 9624207
    Abstract: The present invention provides a novel amorphous Form of azilsartan acid, process for its preparation and pharmaceutical compositions comprising it. The present invention also provides novel crystalline Forms of azilsartan medoxomil, processes for their preparations and pharmaceutical compositions comprising them. The present invention further provides a novel amorphous Form of azilsartan medoxomil potassium, process for its preparation and pharmaceutical compositions comprising it. The present invention further provides a novel process for the preparation of azilsartan medoxomil potassium crystalline Form II.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: April 18, 2017
    Assignee: Hetero Research Foundation
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Matta Ramakrishna Reddy, Bandi Vamsi Krishna
  • Polymorphs of lomitapide and its salts
    Patent number: 9624172
    Abstract: The present invention provides novel polymorphs of Lomitapide, process for their preparation and pharmaceutical compositions comprising them. The present invention also provides a novel polymorph of Lomitapide mesylate, process for its preparation and pharmaceutical compositions comprising it.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: April 18, 2017
    Assignee: Hetero Research Foundation
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Jambula Mukunda Reddy, Bandi Vamsi Krishna
  • PROCESS FOR POMALIDOMIDE
    Publication number: 20170088537
    Abstract: The present invention provides a novel process for the preparation of pomalidomide crystalline Form I. The present invention also provides a process for the purification of pomalidomide.
    Type: Application
    Filed: October 1, 2015
    Publication date: March 30, 2017
    Applicant: HETERO RESEARCH FOUNDATION
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Matta Ramakrishna Krishna Reddy, Bandi Vamsi Krishna
  • Polymorphs of darunavir
    Patent number: 9580440
    Abstract: The present invention provides novel solvated forms of darunavir and processes for their preparation. The present invention also provides novel processes for the preparation of darunavir amorphous form and pharmaceutical compositions comprising it. Thus, for example, darunavir 2-methyl-2-butanol solvate was dissolved in methylene dichloride, distilled under vacuum at 45° C. to obtain a residue, cyclohexane was added to the residue and stirred for 30 hours at 20 to 25° C., and the separated solid was filtered, washed with cyclohexane and dried under vacuum at 50° C. for 12 hours to yield darunavir amorphous form.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: February 28, 2017
    Assignee: HETERO RESEARCH FOUNDATION
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Rapolu Raji Reddy, Kesireddy Subash Chander Reddy, Bandi Vamsi Krishna
  • PROCESS FOR CABAZITAXEL
    Publication number: 20170029392
    Abstract: The present invention provides an improved process for the preparation of 4?-acetoxy-2?-benzoyloxy-5?,20-epoxy-1?,13?-dihydroxy-7?,10?-dimethoxy-9-oxo-11-taxene (7?,10?-dimethoxy-10-deacetoxybaccatin III). The present invention also provides a novel process for the preparation of cabazitaxel.
    Type: Application
    Filed: December 14, 2015
    Publication date: February 2, 2017
    Applicant: HETERO RESEARCH FOUNDATION
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Adulla Venkat Narsimha Reddy, Bandi Vamsi Krishna