Abstract: A textile graft includes a tubular wall disposed between a first open end and an opposed second open end and having an inner surface and an opposed outer surface. The tubular wall includes a textile construction of one or more filaments or yarns, the textile construction by itself being permeable to liquid. A portion of the inner surface of the tubular wall includes a coating of a substantially water-soluble material thereon. The outer surface includes a coating of a substantially water-insoluble elastomeric sealant disposed thereon. The tubular wall having the coating of the substantially water-insoluble elastomeric sealant is, after curing thereof, substantially impermeable to liquid.

Abstract: An implantable tubular textile graft includes a water-insoluble elastomeric sealant disposed at the textile tubular wall such that the graft is impermeable to water at 120 mm Hg pressure. The inner surface of the textile tubular wall configured to promote growth of biological tissue and/or promote growth of pseudointima.

Abstract: A medical textile product includes a textile substrate having opposed first and second surfaces with the textile substrate including a textile construction of one or more yarns. The second surface includes a coating of a substantially water-insoluble, non-porous elastomeric sealant. The one or more yarns at the first surface are pre-treated with a removable composition, such that the water-insoluble elastomeric sealant encapsulates a portion of fibers of the one or more yarns at the second surface of the textile substrate. The textile substrate is substantially impermeable to fluid. The first surface is substantially free of the substantially water-insoluble elastomeric sealant. The textile substrate may be a non-tubular substrate, such as a planar sheet, a shaped sheet, and a tape, or a tubular substrate, such as a cylindrical conduit, a tubular conduit, a Y-shaped, a T-shaped conduit, a multi-channel conduit, and a bulbous shaped conduit.

Abstract: A method of detecting the presence or absence of a sealant applied to a textile graft includes the steps of: providing a textile graft having a first surface and an opposed second surface; providing a water soluble masking agent; applying the water soluble masking agent to at least a portion of the first surface of the textile graft; providing a sealant solution; providing a visual indicator; applying the water insoluble sealing agent and the visual indicator to the second surface of the textile graft; and removing the water soluble masking agent after the step of applying sealing solution. The second surface has visual indication of the visual indicator and the first surface is substantially free of visual indication of the visual indicator. An implantable textile graft includes the selectively applied visual indicator.

Abstract: A method of detecting the presence or absence of a sealant applied to a textile graft includes the steps of: providing a textile graft having a first surface and an opposed second surface; providing a water soluble masking agent; applying the water soluble masking agent to at least a portion of the first surface of the textile graft; providing a sealant solution; providing a visual indicator; applying the water insoluble sealing agent and the visual indicator to the second surface of the textile graft; and removing the water soluble masking agent after the step of applying sealing solution. The second surface has visual indication of the visual indicator and the first surface is substantially free of visual indication of the visual indicator. An implantable textile graft includes the selectively applied visual indicator.

Abstract: An implantable textile graft includes a textile tubular wall of liquid permeable textile construction of one or more yarns having opposed inner and outer surfaces. A portion of the inner surface includes a removable coating. The outer surface includes a coating of a water-insoluble, non-porous elastomeric sealant, such as a silicone-containing polymer, a polyurethane-containing polymer, and/or a polycarbonate-containing polymer, for limiting movement of fluid through the wall. The textile tubular wall is, after curing of the sealant, impermeable to water at 120 mm Hg pressure. The removable coating prevents migrating of the outer coating onto the inner surface of the textile tubular wall and the removable coating is removed prior to implantation of the graft. The portion of the inner surface of the textile tubular wall is substantially free of the water-insoluble elastomeric sealant following removal of the removable coating.

Abstract: A medical textile product includes a textile substrate having opposed first and second surfaces with the textile substrate including a textile construction of one or more yarns. The second surface includes a coating of a substantially water-insoluble, non-porous elastomeric sealant. The one or more yarns at the first surface are pre-treated with a removable composition, such that the water-insoluble elastomeric sealant encapsulates a portion of fibers of the one or more yarns at the second surface of the textile substrate. The textile substrate is substantially impermeable to fluid. The first surface is substantially free of the substantially water-insoluble elastomeric sealant. The textile substrate may be a non-tubular substrate, such as a planar sheet, a shaped sheet, and a tape, or a tubular substrate, such as a cylindrical conduit, a tubular conduit, a Y-shaped, a T-shaped conduit, a multi-channel conduit, and a bulbous shaped conduit.

Abstract: A method of manufacturing a tubular graft may include the steps of: providing a textile including a tubular wall disposed between a first open end and an opposed second open end, an inner surface and an opposed outer surface defining an interior wall portion therein between, the tubular wall including a textile construction of one or more filaments or yarns, the textile construction by itself being permeable to liquid; applying a substantially water-soluble material to at least a portion of the tubular wall; and applying a substantially water-insoluble sealant to at least a part of the outer surface of the tubular wall, the substantially water-insoluble sealant being configured to mitigate movement of fluid through the wall of the conduit; where the water-soluble material is configured to mitigate penetration of the sealant to the inner surface of the conduit.

Abstract: A substantially fluid impermeable textile graft may be produced by selective application of a substantially water-soluble material or masking agent, and optionally selective removal of excess substantially water-soluble material, followed by the application of a substantially water-insoluble sealant. The inner surface of the graft includes a coating of the substantially water-soluble material thereon. The outer surface includes a coating of the substantially water-insoluble sealant disposed thereon. The tubular wall having the coating of the substantially water-insoluble sealant is, after curing thereof, substantially impermeable to liquid. The substantially water-soluble material is removed from the graft after the application of the substantially water-insoluble sealant.

Abstract: A textile graft includes a tubular wall disposed between a first open end and an opposed second open end and having an inner surface and an opposed outer surface. The tubular wall includes a textile construction of one or more filaments or yarns, the textile construction by itself being permeable to liquid. A portion of the inner surface of the tubular wall includes a coating of a substantially water-soluble material thereon. The outer surface includes a coating of a substantially water-insoluble elastomeric sealant disposed thereon. The tubular wall having the coating of the substantially water-insoluble elastomeric sealant is, after curing thereof, substantially impermeable to liquid.

Abstract: A textile graft includes a tubular wall disposed between a first open end and an opposed second open end and having an inner surface and an opposed outer surface. The tubular wall includes a textile construction of one or more filaments or yarns, the textile construction by itself being permeable to liquid. A portion of the inner surface of the tubular wall includes a coating of a substantially water-soluble material thereon. The outer surface includes a coating of a substantially water-insoluble elastomeric sealant disposed thereon. The tubular wall having the coating of the substantially water-insoluble elastomeric sealant is, after curing thereof, substantially impermeable to liquid.