Patents Assigned to Howard W. Bremer
  • Patent number: 4717721
    Abstract: This invention relates to a method for enhancing cell differentiation in malignant cells by exposing the cells to a 1.alpha.-hydroxylated vitamin D derivative characterized by a 17-side chain greater in length than the cholesterol or ergosterol side chains.The method finds application in the treatment of neoplastic diseases including leukemoid diseases and, specifically, leukemia.
    Type: Grant
    Filed: May 30, 1985
    Date of Patent: January 5, 1988
    Assignee: Howard W. Bremer
    Inventors: Hector F. DeLuca, Heinrich K. Schnoes, Nobuo Ikekawa, Voula Ostrem