Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3. Suitable compounds include but are not limited to, for example, substituted quinazolin-4-ones of formula I.
Type:
Grant
Filed:
November 3, 2006
Date of Patent:
February 22, 2011
Assignee:
Hydra Biosciences, Inc.
Inventors:
Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, Jr., Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
Type:
Application
Filed:
April 6, 2010
Publication date:
October 28, 2010
Applicant:
Hydra Biosciences, Inc.
Inventors:
Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
Type:
Grant
Filed:
May 9, 2006
Date of Patent:
September 28, 2010
Assignee:
Hydra Biosciences, Inc.
Inventors:
Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, Jr., Anu Mahadevan, Peter Meltzer, Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
Type:
Application
Filed:
November 3, 2006
Publication date:
June 17, 2010
Applicant:
Hydra Biosciences Inc.
Inventors:
Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Anu Mahadevan, Peter Meltzer, Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
Type:
Application
Filed:
May 12, 2008
Publication date:
January 15, 2009
Applicant:
Hydra Biosciences Inc.
Inventors:
Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, Magdalene M. Moran, Howard Ng, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
Type:
Application
Filed:
September 14, 2007
Publication date:
June 19, 2008
Applicant:
Hydra Biosciences Inc.
Inventors:
Magdalene M. Moran, Jayhong A. Chong, Christopher Fanger, Amy Ripka, Glenn R. Larsen, Xiaoguang Zhen, Dennis John Underwood, Manfred Weigele
Abstract: The invention provides novel compositions and compounds that inhibit CatSper channel activity, that preferentially inhibits sperm hyperactivity over sperm motility, or both. The compounds of the invention are useful as contraceptive agents that may be adminstered to males, females, or concurrently to both sexual partners. The invention further provides methods of conducting drug discovery business and of conducting a reproductive medicine business. The invention also provides methods of identifying compounds that modulate sperm hypermotility.