Abstract: This disclosure features dinucleotide compounds that modulate Stimulator of Interferon Genes (STING) activity, for use for example in the treatment of cancer. This disclosure also features compositions as well as other methods of using and making the same (Formula (A)). A and B are each independently selected from the group consisting of Formulae (i), (ii), (iii), and (iv).
Type:
Application
Filed:
January 11, 2017
Publication date:
January 17, 2019
Applicant:
Innate Tumoir Immunity, Inc.
Inventors:
Gary Glick, Shomir Ghosh, Edward James Olhava, William R. Roush, Roger Jones