Patents Assigned to Innobio Corporation Limited
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Patent number: 12127578Abstract: The present invention discloses a microencapsuled conjugated linoleic acid glyceride powder and a preparation method thereof. The preparation method comprises the steps of preparing raw materials, preparing an aqueous phase and an oil phase, preparing an emulsion, and spray drying. The raw materials comprise, in parts by mass: 60-85 parts of conjugated linoleic acid glyceride, 5-35 parts of starch or colloid, 4-20 parts of small molecule filler, and 0.01-5 parts of antioxidant.Type: GrantFiled: October 26, 2018Date of Patent: October 29, 2024Assignee: INNOBIO CORPORATION LIMITEDInventors: Xiang Ren, Yutao Xu, Zhongle Tian, Jianbin Chen, Wenzhong Wu
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Publication number: 20240016741Abstract: The disclosure provides a carotenoid preparation, its preparation method and application. The method includes: obtaining pretreated carotenoid by mixing carotenoid and ethanol aqueous solution, stirring, and then dispersing through high-speed shearing, adding antioxidant, and removing solvent until ethanol solution residue is less than 10 ppm, a moisture content of the pretreated carotenoid being within a range of 10%-30%; obtaining a pretreated gelling wall material by preparing an aqueous solution with a first solid content through mixing wall material and carbohydrate, stirring, and dispersing; and obtaining the carotenoid preparation by mixing the pretreated carotenoid and the pretreated gelling wall material, emulsifying, and granulating.Type: ApplicationFiled: July 23, 2023Publication date: January 18, 2024Applicant: INNOBIO CORPORATION LIMITEDInventors: Qian LI, Chao FAN, Yongde HONG, Xiang REN, Wenzhong WU
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Patent number: 10865225Abstract: Provided is a gene encoding alanyl-glutamine dipeptide biosynthetic enzyme and the application thereof. The nucleotide sequence of said gene is shown in SEQ ID NO: 1. Further, provided is an amino acid sequence encoded by the gene, and provided recombinant vector, recombinant E. coli, recombinant S. cerevisiae, and a self-flocculating recombinant S. cerevisiae containing the gene. Furthermore, provided is a method for carrying out bioconversion to synthesize alanyl-glutamine dipeptide by using said recombinant microorganisms. The application of the gene and recombinant batteries has the characteristics of high molar conversion rate, fast production rate and repeated recycling of the bacteria. It is a good choice for efficient, environmentally friendly and economical production of alanyl-glutamine dipeptide. In addition, through the recycling process, it is expected to reduce the cost of industrial production, solve the problems of difficult enzyme recovery, low utilization rate and unstable enzyme activity.Type: GrantFiled: June 27, 2019Date of Patent: December 15, 2020Assignee: INNOBIO CORPORATION LIMITEDInventors: Wenjie Yuan, Chao Fan, Yimin Li, Hao Hong, Wenzhong Wu
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Patent number: 10555909Abstract: Microencapsulation of ?-alanine uses ?-alanine as a core material and a mixture of a wall material and an additive as a release material. The additive comprises: a fatty acid-based saturated or unsaturated fatty acid glyceride containing 12-22 carbon atoms and a phospholipid. The fatty acid glyceride is a mono-fatty acid glyceride or a di-fatty acid glyceride, or a mixture formed by mixing the mono-fatty acid glyceride and the di-fatty acid glyceride at arbitrary proportions. The microencapsulation technique solves problems occurring with the use of ?-alanine as a raw material, such as high moisture absorption tendency thereof, unpleasant smell and stinging accompanying administration of the same.Type: GrantFiled: December 25, 2016Date of Patent: February 11, 2020Assignee: INNOBIO CORPORATION LIMITEDInventors: Wenzhong Wu, Jianbin Chen, Qian Li, Xiangcheng Li
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Patent number: 10525008Abstract: The invention relates to a microencapsulated amino acid composition and methods of manufacturing this composition. Amino acids, such as branched-chain amino acids, have low water solubility, poor hydrophilicity, and poor stability. Amino acids are thus difficult to be digested and absorbed. Consequently amino acids can hardly meet human needs of consuming. This microencapsulated amino acid composition that can quickly disperse and dissolve in cold water, resulting clear solution. The method includes (1) adding coating agents, wetting agents, or other excipients to the amino acid mixture, (2) modifying the surface of microencapsulated particles to considerably accelerate the wetting speed. In this composition, the weight ratio of amino acids and excipients is from 100/0.1 to 100/10.0.Type: GrantFiled: October 11, 2013Date of Patent: January 7, 2020Assignee: INNOBIO CORPORATION LIMITEDInventors: Wenzhong Wu, Jianbin Chen, Yuemei Zhang
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Publication number: 20190008786Abstract: Microencapsulation of ?-alanine uses ?-alanine as a core material and a mixture of a wall material and an additive as a release material. The additive comprises: a fatty acid-based saturated or unsaturated fatty acid glyceride containing 12-22 carbon atoms and a phospholipid. The fatty acid glyceride is a mono-fatty acid glyceride or a di-fatty acid glyceride, or a mixture formed by mixing the mono-fatty acid glyceride and the di-fatty acid glyceride at arbitrary proportions. The microencapsulation technique solves problems occurring with the use of ?-alanine as a raw material, such as high moisture absorption tendency thereof, unpleasant smell and stinging accompanying administration of the same.Type: ApplicationFiled: December 25, 2016Publication date: January 10, 2019Applicant: Innobio Corporation LimitedInventors: Wenzhong WU, Jianbin CHEN, Qian LI, Xiangcheng LI