Abstract: The present invention relates to a novel recombinant porcine circovirus type 2 protein and use thereof and, more specifically, to: a novel recombinant porcine circovirus type 2 protein; and a vaccine composition, an immunogenic composition, and a feed composition, comprising same. It was confirmed that the novel recombinant porcine circovirus type 2 protein according to the present invention showed excellent antibody titers against both PCV2b and type 2d. This means that when the recombinant porcine circovirus type 2 protein of the present invention is used as a vaccine, porcine circovirus-related diseases can be effectively prevented by cross-protecting both PCV2b and PCV2d genotypes, and thus the porcine circovirus type 2 protein of the present invention can be used in various ways in the field of pig farming.