Abstract: The present invention concerns radioactive rhodium complexes, their preparation methods, and their use for the radiolabelling of biomolecules, especially monoclonal antibodies.
Type:
Application
Filed:
May 14, 2013
Publication date:
May 21, 2015
Applicants:
Institut National de la Sante et de la Recherche (INSERM), Chu Nantes, Universite de Nantes, Centre National de la Recherche Scientifique (C.N.R.S.), Universite d' Angers
Abstract: The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL. The invention also concerns models and products for treating CADASIL and related diseases.
Type:
Grant
Filed:
May 17, 1999
Date of Patent:
March 25, 2003
Assignees:
Institut National de la Sante et de la Recherche
(INSERM), Assistance Publique - Hopitaux de Paris
Inventors:
Elisabeth Tournier-Lasserve, Anne Joutel, Marie-Germaine Bousser, Jean-François Bach