Patents Assigned to Institut National de Recherche Pour L'Agriculture, L'Alimentation et L'Environnement
  • Patent number: 11344586
    Abstract: The present invention provides methods for determining if a patient is likely to benefit from a cancer treatment, by determining if said patient has a gut dysbiosis with an over representation of certain bacterial species. The present invention also provides probiotic strains to improve the efficacy of a cancer treatment, especially chemotherapy, in patients in need thereof.
    Type: Grant
    Filed: April 21, 2020
    Date of Patent: May 31, 2022
    Assignees: INSTITUT GUSTAVE ROUSSY, UNIVERSITE PARIS-SACLAY, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
    Inventors: Laurence Zitvogel, Ivo Gomperts Boneca, Patricia Lepage, Sophie Viaud, Romain Daillere
  • Patent number: 11337440
    Abstract: A method for producing an assembly of at least one dairy protein and at least one vegetable protein, and the assembly obtained by the method. Also, the uses of the assembly, in particular in the food processing field.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: May 24, 2022
    Assignees: ROQUETTE FRERES, INGREDIA, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
    Inventors: Bernard Boursier, Emmanuelle Moretti, Guillaume Ribadeau-Dumas, Saliha Belaid, Alain Riaublanc, Jacques Gueguen, Anne Lepoudere, Jean-Jacques Snappe, Isabelle Colin
  • Patent number: 11332600
    Abstract: Disclosed is a method for producing nanocelluloses from a cellulose substrate including cellulose fibers, the method including the following sequence of steps: —a step of enzymatic treatment of the cellulose substrate, by bringing same into contact with at least one cleaving enzyme, then—a step of mechanical treatment of the cellulose substrate subjected to the step of enzymatic treatment, in order to delaminate the cellulose fibres and obtain the nanocelluloses. The at least one cleaving enzyme is chosen from the enzymes belonging to the family of lytic polysaccharide monooxygenases (LPMOs) capable of achieving cleavage in the presence of an electron donor. Also disclosed are the nanocelluloses obtained according to the method.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: May 17, 2022
    Assignee: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
    Inventors: Bernard Cathala, Ana Villares, Jean-Guy Berrin, Celine Moreau
  • Publication number: 20220143070
    Abstract: A nutraceutical composition including one or more sources of fiber, glutamine, one or more probiotics, one or more sources of omega-3, and one or more antioxidants, for use in the prevention and/or treatment of dysbiosis of the intestinal microbiota. Also, a method for preventing and/or treating dysbiosis including a step of administering the nutraceutical composition to a patient in need thereof. Further, a three-part kit for use in the prevention and/or treatment of dysbiosis of the intestinal microbiota.
    Type: Application
    Filed: March 5, 2020
    Publication date: May 12, 2022
    Applicants: MATIVA TECH, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
    Inventors: Hélène DUMINY, Alain VERNEAU, Luc HEITZ, Joël DORÉ
  • Publication number: 20220145232
    Abstract: The present invention relates to a processing method at acidic or neutral pH in a reactor (4) for processing lignocellulosic biomass (P), said process including a continuous cleaning phase of the reactor which comprises introducing a basic aqueous solution (EB) into said reactor containing the biomass being processed.
    Type: Application
    Filed: December 13, 2019
    Publication date: May 12, 2022
    Applicants: IFP Energies nouvelles, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENT
    Inventors: Meriem BOURAS, Caroline AYMARD, Olivier CARNNOT
  • Patent number: 11319516
    Abstract: The present invention relates to the use of a cysteine endoprotease or a malt extract to prevent or reduce the cloudiness of a cereal-based beverage, fermented or not.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: May 3, 2022
    Assignees: MALTERIES SOUFFLET, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE. L'ALIMENTATION ET L'ENVIRONNEMENT
    Inventors: Michel Lopez, Myriam Fliss, Didier Gilbert Marion
  • Publication number: 20220119835
    Abstract: The present invention relates to a plant obtained by mutagenesis, such that the expression and/or the activity of the ESK1 protein and the expression and/or the activity of the TPS7 protein are diminished compared to a non-mutagenated plant. Said plant with biomass that has better digestibility maintains satisfactory growth. A further aim of the present invention is a method for preparing said plant, as well as the use of said plant for the production of biofuel.
    Type: Application
    Filed: February 7, 2020
    Publication date: April 21, 2022
    Applicant: Institut National de Recherche Pour l'Agriculture, L'Alimentation et L'Environnement
    Inventors: Christine Horlow, Marie-Hélène Durand-Tardif, Gregory Mouille, Peter Rogowsky
  • Publication number: 20220056395
    Abstract: The present invention concerns a method for cleaning a reactor (4) for treating a lignocellulosic biomass (P), said method comprising the following steps: a) draining the reactor of the reaction mixture containing the biomass, b) filling the reactor with a basic aqueous solution (EB), c) draining the reactor, d) injecting steam (V) into the reactor, e) filling the reactor with an aqueous solution (E), f) draining the reactor.
    Type: Application
    Filed: December 13, 2019
    Publication date: February 24, 2022
    Applicants: IFP Energies nouvelles, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENT
    Inventors: Meriem BOURAS GALINIE, Caroline AYMARD, Olivier CARNNOT
  • Patent number: 11253537
    Abstract: Polypeptides having the ability to specifically form connections of glucosyl units in alpha 1,3 on an acceptor having at least one hydroxyl moiety are presented. The polypeptides include i) the pattern I of sequence SEQ ID NO: 1, ii) the pattern II of sequence SEQ ID NO: 2, iii) the pattern III of sequence SEQ ID NO: 3, and iv) the pattern IV of sequence SEQ ID NO: 4, or derivates from one or several of said patterns, wherein the polypeptide furthermore has an aspartic residue (D) at position 5 of the pattern II (SEQ ID NO: 2), a glutamic acid residue (E) at position 6 of the pattern III (SEQ ID NO: 3) an an aspartic acid residue (D) at position 6 of the pattern IV (SEQ ID NO: 4). Methods for producing acceptors connected to glucosyl units in alpha 1,3 using the polypeptides are also provided.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: February 22, 2022
    Assignees: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Magali Remaud-Simeon, Marlene Vuillemin, Claire Moulis, Pierre Monsan, Sandrine Morel
  • Patent number: 11236357
    Abstract: Disclosed is a method for the production of a plant of the Cucurbitaceae family by mutating seeds to induce a mutation of 1-aminocyclopropane-1-carboxylate synthase 8 (ACS8) and growing a plant from the mutated seed, with the plant having a androecy or androecious tendency.
    Type: Grant
    Filed: November 7, 2019
    Date of Patent: February 1, 2022
    Assignees: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, VILMORIN ET CIE
    Inventors: Abdelhafid Bendahmane, Christelle Troadec, Adnane Boualem, Daniele Hosemans, Julie Fauve
  • Patent number: 11236132
    Abstract: The present invention relates to novel fusion polypeptides and the uses thereof. The invention particularly relates to conjugated coat proteins derived from nepoviruses, virus-like particles made with such proteins, and the uses thereof. The particles of the invention can expose and/or encage molecules of interest and have utility in various fields such as the pharmaceutical, agro, or veterinary areas.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: February 1, 2022
    Assignees: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Lorène Belval, Gérard Demangeat, Caroline Hemmer, Christophe Ritzenthaler
  • Patent number: 11110133
    Abstract: The invention relates to a lyophilized composition comprising a microbiota in its ecosystem, in particular stools, and a mixture of cryoprotectant agents comprising maltodextrin and trehalose, a capsule comprising said lyophilized composition, the use thereof, and methods for the production thereof.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: September 7, 2021
    Assignees: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, UNIVERSITE PARIS DESCARTES, UNIVERSITE PARIS DIDEROT—PARIS 7, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
    Inventors: Nathalie Kapel, Anne-Judith Waligora-Dupriet, Muriel Thomas, Christine Charrueau, Francisca Joly, Camille Mayeur, Véronique Robert, Johanne Delannoy
  • Publication number: 20210268044
    Abstract: The present invention disclosure relates to a new probiotic strain of Lactobacillus brevis, isolated from pique and exhibiting anti-cancer properties, as welt as to compositions which contain said strain.
    Type: Application
    Filed: June 5, 2019
    Publication date: September 2, 2021
    Applicants: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, INSTITUTO POLITECNICO NACIONAL (IPN)
    Inventors: Luis BERMUDEZ HUMARAN, Edgar TORRES MARAVILLA, Philippe LANGELLA, Maria Elena SANCHEZ-PARDO
  • Patent number: 11013783
    Abstract: A method for preventing or treating an inflammatory disease, such as inflammatory bowel disease and Crohn disease, is presented. The method includes administering to a patient a polypeptide having the amino acid sequence of SEQ ID NO: 1, a conservative derivative or a fragment thereof, a nucleic acid sequence encoding said polypeptide, a vector comprising said nucleic acid sequence or a host cell that has been transfected, infected or transformed by said nucleic acid sequence and/or by said vector.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: May 25, 2021
    Assignee: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
    Inventors: Philippe Langella, Benedicte Pigneur-Arnaud, Jean-Marc Chatel, Elodie Quevrain, Philippe Seksik, Germain Trugnan, Florian Chain, Luis G Bermudez-Humaran, Marie-Anne Maubert, Christophe Michon, Harry Sokol
  • Patent number: 10981957
    Abstract: The present invention relates to a new class of peptides having antibacterial activity and presenting D-amino acids and their uses. It also relates to a new enzyme presenting a peptide epimerase activity in vitro and in vivo, thereby being useful for modifying peptides in order to change the amino acid configuration from L to D.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: April 20, 2021
    Assignee: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
    Inventors: Alhosna Benjdia, Alain Guillot, Olivier Berteau
  • Patent number: 10980839
    Abstract: The present invention relates to a method for preparing a fecal 5 microbiota sample of a donor subject. Said method includes the following steps: a) collecting at least one fecal microbiota sample from the donor subject; b) within a period of less than 5 minutes after collecting the sample, placing said sample obtained in step a) in an oxygen-tight collection device; c) mixing the sample obtained in step b) with at least one aqueous saline 10 solution containing at least one cryoprotectant and/or a filling agent; d) optionally, filtering the mixture obtained in step c), in particular by means of a filter comprising pores having a diameter of less than or equal to 0.7 mm, preferably less than or equal to 0.5 mm; and e) storing the mixture obtained in step c) or d) by freezing said mixture at a temperature 15 of between ?15° C. and ?100° C. Steps b) to e) are carried out in anaerobiosis.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: April 20, 2021
    Assignees: MAAT PHARMA, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
    Inventors: Hervé Affagard, Carole Schwintner, Catherine Juste, Joël Dore, Patricia Lepage, Christel Maillet, Sylvie Rabot, Fernanda Fonseca, Hervé Blottiere
  • Patent number: 10883112
    Abstract: The invention relates to plants wherein the protein OSD1, involved in the transition from meiosis I to meiosis II is inactive. These plants produce Second Division Restitution (SDR) 2n gametes. The invention further relates to plants wherein the inactivation of OSD1 is combined with the inactivation of a gene involved in meiotic recombination in plants, and of a gene involved in the monopolar orientation of the kinetochores during meiosis. These plants produce apomeiotic gametes. These plants are useful in plant breeding.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: January 5, 2021
    Assignee: Institut National de Recherche Pour l'Agriculture, l'Alimentation et l'Environnement
    Inventors: Raphael Mercier, Isabelle D'Erfurth, Nicole Froger, Sylvie Jolivet, Laurence Cromer
  • Patent number: 10842808
    Abstract: Polypeptides having the ability to specifically form connections of glucosyl units in alpha 1,3 on an acceptor having at least one hydroxyl moiety are presented. The polypeptides include i) the pattern I of sequence SEQ ID NO: 1, ii) the pattern II of sequence SEQ ID NO: 2, iii) the pattern III of sequence SEQ ID NO: 3, and iv) the pattern IV of sequence SEQ ID NO: 4, or derivates from one or several of said patterns, wherein the polypeptide furthermore has an aspartic residue (D) at position 5 of the pattern II (SEQ ID NO: 2), a glutamic acid residue (E) at position 6 of the pattern III (SEQ ID NO: 3) and an aspartic acid residue (D) at position 6 of the pattern IV (SEQ ID NO: 4). Methods for producing acceptors connected to glucosyl units in alpha 1,3 using the polypeptides are also provided.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: November 24, 2020
    Assignees: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Magali Remaud-Simeon, Marlene Vuillemin, Claire Moulis, Pierre Monsan, Sandrine Morel
  • Patent number: 10829827
    Abstract: The present disclosure concerns a process for obtaining a variant yeast strain capable of producing less ethanol in an alcoholic fermentation process than its corresponding ancestral strain. The variant yeast strain is obtained by culturing the ancestral strain in the presence of increasing concentrations of a salt capable of causing an hyperosmotic stress to the ancestral yeast strain. The present disclosure also concerns variant yeast strain obtained from this process (for example the variant yeast strain deposited at Institut Pasteur, on Jan. 9, 2014, under accession number CNCM I-4832, the variant yeast strain deposited at Institut Pasteur, on Oct. 18, 2012 under accession number CNCM I-4684, the variant yeast strain deposited at Institut Pasteur, on Oct. 18, 2012 under accession number CNCM I-4685 and/or the variant yeast strain deposited at Institut Pasteur on Jan. 28, 2015 under accession number CNCM I-4952) as well as processes using the variant yeast strain (wine fermentation for example).
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: November 10, 2020
    Assignees: DANSTAR FERMENT AG, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
    Inventors: Valentin Tilloy, Anne Ortiz-Julien, Jessica Noble, Sylvie Dequin
  • Publication number: 20200330568
    Abstract: The present invention relates to a strain of Neospora caninum for use in treating cancer or infectious diseases.
    Type: Application
    Filed: July 1, 2020
    Publication date: October 22, 2020
    Applicants: UNIVERSITÉ DE TOURS, KYMERIS THERAPEUTICS INC., Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
    Inventors: Isabelle DIMIER-POISSON, Marie-Noëlle MEVELEC, Céline DUCOURNAU, Nathalie MOIRE, Richard MCCRAE