Abstract: Disclosed herein are compositions and methods for the treatment of skeletal muscle and/or the protection of skeletal muscle against injury. The adenosine A3 receptor has been identified as a new therapeutic target for the treatment of skeletal muscle. Adenosine A3 receptor agonists are used treat subjects with skeletal muscle ischemia and reperfusion (I/R) injuries, individuals with skeletal muscle disorders, and individuals suffering from skeletal muscle injury resulting from physical exertion.
Type:
Application
Filed:
March 25, 2008
Publication date:
December 18, 2008
Applicants:
Institute of Enviromental Medicine
Inventors:
Bruce Tsan-Tang Liang, Edward John Zambraski