Patents Assigned to Institute of Nuclear Energy Research Atomic Energy Council, Executive Yuan
  • Patent number: 11260345
    Abstract: A desiccant wheel is provided to be rotatable. Through the body of the wheel or a surface adsorbent, water vapor in humid air flow is adsorbed. By passing a high-temperature air flow through the wheel, the body or surface coating is regenerated with moisture removed. Along a cross-section radial, the wheel is divided into different areas. The body has three-dimensionally inter-connected pores. The pores can be of different types. The wheel is a complete concentric cylinder or a concentric cylinder comprising equal or unequal sectors. The equal or unequal sectors are separated with each other. The wheel can rotate at a fixed speed for continually repeating a process of adsorbing, transiting, and regenerating. Thereby, drying can be carried out without causing physical or chemical change to heat-sensitive material, which also improves drying efficiency, reduces size, lowers power consumption, and helps in carbon reduction for industry.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: March 1, 2022
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Heng Yi Li, Tsair-Fuh Huang, Sheng-Fu Yang, Po-Hsiu Kuo, Yu-Ren Chen, How-Ming Lee, To-Mei Wang
  • Patent number: 11258263
    Abstract: An apparatus of solid oxide fuel cells (SOFC) is provided. The SOFCs generate power and are grid-tied. The apparatus comprises a power-generating side; and a grid-connecting side using an elementary household power management. The apparatus solves problems like low voltage, high current, voltage oscillation, voltage dips, long generator-starting time, etc. The apparatus is not only used as a stable power supply (base load), but also helps adjust the regional peak electricity demands. The features include the following: 1. A grid is tied, where output power does not pass through a direct-current boost converter and, thus, has no loss from it. 2. Injures, including voltage oscillation and sudden unloading after dumping, are reduced for avoiding further damages to cell sheets. 3. With the coordination of elementary power management and the integration of grid, the limitation of long-awaiting generator-starting time is crossed out and convenience of immediate power use is achieved.
    Type: Grant
    Filed: March 3, 2021
    Date of Patent: February 22, 2022
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Fang-Tzu Chuang, Chen-Min Chan, Ruey-Yi Lee
  • Patent number: 11251452
    Abstract: A method is provided for restoring an electrolyte of vanadium (V) redox flow battery (VRFB). Electrolyte data of an original system are analyzed in advance. A reusable positive electrode is further equipped with a V electrolyte. A reductant for a stack of VRFB is used in coordination as an electrolysis device. After a long-term reaction with a VRFB having a high valence (greater than 3.5), an electrolyte at the positive electrode is directed out to a negative electrode of the electrolysis device; and, then, electrolysis is processed after accurate calculation. In the end, the internal fluid balancing method of the original system is combined. Thus, a harmless and quick valence restoration is processed for the electrolyte of the original system, which is a final resort for the restoration of V electrolyte.
    Type: Grant
    Filed: January 8, 2020
    Date of Patent: February 15, 2022
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Yu-De Zhuang, Chien-Hong Lin, Yi-Hsin Hu, Han-Wen Chou, Hwa-Jou Wei, Ning-Yih Hsu
  • Patent number: 11247947
    Abstract: A method is provided to purify [F-18]FEONM under a high pressure. The synthesis processes of [F-18]FEONM are integrated. An isolation process of non-toxic radio-high performance liquid chromatography (radio-HPLC) is used to purify the crude product. The method integrates a convention [F-18]FDG synthesizer and a novel radio-HPLC system together in a heat chamber. After radiofluorinating the precursor, the reaction product is purified with an alumina solid-phase column in advance to obtain the crude product while fluorine-18 is removed. Then, diphenyl semipreparative HPLC column is used for a final purification. A non-toxic solvent is used for mobile-phase eluting to remove the unreacted precursor and the phase-transfer solvent. The radiofluorination has a reaction yield about 50 percent (%). The method has an uncorrected radiochemical yield of 10˜20%. Both of the radio-HPLC and the radio-thin layer chromatography (radio-TLC) have radiochemical purity higher than 95%.
    Type: Grant
    Filed: January 4, 2021
    Date of Patent: February 15, 2022
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Yean-Hung Tu, Li-Yuan Huang, Jenn-Tzong Chen, Tsai-Yueh Luo, Shiou-Shiow Farn, Wuu-Jyh Lin
  • Patent number: 11232950
    Abstract: The invention is a special designed pattern heterogeneous substrate, which is epitaxially deposited on a heterogeneous substrate by two step growth, and a thermal cycle annealing is added to reduce the lattice mismatch between the layers and the difference in thermal expansion coefficient, thereby obtaining a better stress. The quality of the semiconductor epitaxial layer is improved, and the present invention can easily grasp the timing of stress release when the semiconductor is grown on the heterogeneous substrate, avoid cracks in the semiconductor epitaxial layer, and form a crack free zone in the middle of the semiconductor epitaxial layer.
    Type: Grant
    Filed: November 1, 2019
    Date of Patent: January 25, 2022
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Jheng Hao Fang, Yu Li Tsai, Hsueh-Hui Yang, Chih Hung Wu, Hwen Fen Hong
  • Patent number: 11191718
    Abstract: The present invention provides an ophthalmic gel and a preparation method thereof. The ophthalmic gel comprises: an antibiotic; a nanocarrier, wherein the nanocarrier is used to load the antibiotic; and a biodegradable matrix, wherein the biodegradable matrix is compatible with the nanocarrier to carry the nanocarrier. When the ophthalmic gel of the present invention is applied to the surface of the cornea and conjunctiva of the eyes, the biodegradable matrix is automatically degraded and the nanocarrier carried by the biodegradable matrix will slowly release the antibiotic, loaded in the nanocarrier, at an appropriate rate to overcome the high-frequency use of general ophthalmic drugs and easily caused blurred vision; the present invention further comprises an ophthalmic gel preparation method.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: December 7, 2021
    Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, R.O.C
    Inventors: Ming-Cheng Chang, Tsai-Yueh Luo, Cheng-Liang Peng, Kuan-Yin Chen
  • Patent number: 11186609
    Abstract: The present invention provides a method for preparing S-Bz-MAG3 as a precursor of contrast media. Thioglycolic acid and benzoyl chloride are taken for the thiol protection reaction. Next, N,N?-dicyclohexylcarbodiimide and N-hydroxysuccinimide are converted to corresponding ester compounds. The corresponding ester compounds then react with triglycine by amide bonding reaction. The product of the reaction is recrystallized using acetone, filtered, and finally flushed using flushing agent to give the final product. This is a bifunctional chelator and can be bridged with 99mTc and 186/188Re effectively and applied to nuclear medicine imaging and tumor radiotherapy. By taking advantage of fewer synthesis steps and ease of operations, complicated separation and purification reactions can be reduced and thus achieving highly productivity of S-Bz-MAG3.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: November 30, 2021
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Ching-Yun Lee, Yu Chang, Cheng-Fang Hsu
  • Patent number: 11077217
    Abstract: The present invention provides a radioactive labeling method for neuropeptide Y (NPY) compound and a mammalian diagnostic radioactive targeting medicine with NPY peptide being modified at position 27th to 36th, and after binding with the chelating agent and labeling the radiation nucleus 66Ga67Ga68Ga177Lu or 111In to provide a radioactive targeting medicine for multi-type breast cancer diagnosis and treatment.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: August 3, 2021
    Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN
    Inventors: Ming-Hsin Li, Su-Jung Chen, Ming-Wei Chen, Yuan-Ruei Huang, Shih-Ying Lee, Chun-Fang Feng, Sheng-Nan Lo, Chih-Hsien Chang
  • Patent number: 11081717
    Abstract: A storage module of distributed flow battery is provided. An electrochemical reaction is processed with the positive and negative electrolytes to produce and/or discharge direct current and further output the positive and negative electrolytes after the reaction. The module comprises two end plates; two frames disposed between the two end plates; two current collectors disposed between the two frames; two complex cast polar plates disposed between the two current collectors; two electrodes disposed between the two complex cast polar plates; a membrane disposed between the two electrodes; and three gaskets. Therein, two of the gaskets are set to sandwich and enclose one of the two complex cast polar plates; and the other one of the gaskets is set between the other one of the two complex cast polar plates and an adjacent one of the current collectors.
    Type: Grant
    Filed: October 3, 2019
    Date of Patent: August 3, 2021
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Ning-Yih Hsu, Chien-Hong Lin, Han-Wen Chou, Chin-Lung Hsieh, Yi-Hsin Hu, Yu-De Zhuang, Yun-Shan Tsai, Qiao-ya Chen
  • Patent number: 11078144
    Abstract: Disclosed herein is a process for chemically synthesizing of hydroquinone derivatives, especially for hydroquinone derivatives with heptadecatrienyl side chain, which is synthesized via a Wittig reaction of 2-(10?-oxononyl)-1,4-diacetoxyl benzene and (3E, 5Z)-3,5-heptadien-1-triphenylphosphonium iodide and then deacetylation. In addition, the product is solid powder.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: August 3, 2021
    Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, R.O.C
    Inventors: Kun-Liang Lin, Ping-Yen Wang, Mei-Hui Wang
  • Patent number: 10948180
    Abstract: A gasification reactor is provided. The reactor comprises a first gasification area, a second gasification area and a shared combustion area. The shared combustion area is set between the first and second gasification areas. Therein, the (present invention applies interconnected fluidized beds in gasification. The connecting piping between the first and second gasification areas are separately replaced with dense beds to be integrated for forming a single reactor. Thus, the present invention simplifies the system, saves the cost and reduces the operation difficulty.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: March 16, 2021
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Yau-Pin Chyou, Po-Chuang Chen, Keng-Tung Wu, Rei-Yu Chein
  • Patent number: 10934314
    Abstract: A method for preparing organoboron derivatives containing oxygen atoms and an aromatic ring as labeled precursors of dopamine positron emission tomography imaging agents is revealed. Hydrochloride salt of cocaine is used as an initiator. Organoboron derivatives containing oxygen atoms are directly produced on an aromatic ring as drug substances and the aromatic ring is directly labeled with radioisotope fluorine-18 (F-18). The method takes only five steps including four steps for preparing organoboron derivatives containing oxygen atoms and an aromatic ring as drug substances and a step of labeling the aromatic ring of the organoboron derivatives with F-18 directly. Not only the process time is significantly reduced, the total yield rate is also improved effectively.
    Type: Grant
    Filed: August 17, 2020
    Date of Patent: March 2, 2021
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Yu Chang, Wen-Ching Wu
  • Patent number: 10925981
    Abstract: The present invention provides a hexa-lactoside-triazanonane triacetic acid (NOTA) derivative, a method for radiolabeling a hexa-lactoside positron emission tomography (PET) imaging agent for a liver receptor with Ga-68, and a hexa-lactoside PET imaging agent for a liver receptor. The hexa-lactoside-NOTA derivative is a conjugate of six chains of lactose with NOTA obtained by conjugating hexa-lactoside to a chelating agent p-thiocyanate-benzyl-triazanonane diacetic acid-glutamic acid in the presence of triethyl amine/dimethyl formamide as a solvent. The radiolabeling method comprises labeling with Ga-68 at room temperature. According to the present invention, the labeling effect is stable, the labeling efficiency of the labeled product is greater than 95%, the labeled product is highly stable and the radiochemical purity is still greater than 90% after 4 hours.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: February 23, 2021
    Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, R.O.C
    Inventors: Wuu-Jyh Lin, Mei-Hui Wang, Hung-Man Yu, Kun-Liang Lin, Yan-Feng Jiang, Rui-Yu Chen
  • Patent number: 10925572
    Abstract: A geometric calibration method for dual-axis digital tomosynthesis includes the steps of: providing a calibration phantom having a first plate, a second plate parallel to the first plate, and mark points distributed to the first and second plates; arranging any mark point at the first plate not to be vertically collinear with a mark point at the second plate; projecting the calibration phantom onto a planar detector to obtain a projected calibration-phantom image; deriving a conversion relationship between the mark point and the corresponding projected position at the planar detector to further establish a projection matrix related to an imaging system; and, applying the projection matrix to calculate a plurality of geometric parameters. In addition, a geometric calibration system for dual-axis digital tomosynthesis is also provided.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: February 23, 2021
    Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, R.O.C
    Inventors: Chia-Hao Chang, Sheng-Pin Tseng, Yu-Ching Ni, Fan-Pin Tseng
  • Patent number: 10920742
    Abstract: A noise-reduction device for a wind turbine and the wind turbine applied thereof are introduced. The noise-reduction device has a body. The body has a connection portion and a spoiler. The connection portion is concavely disposed on one side of the body and corresponds in shape to the wind turbine's blade so as to be fixed to a confronting edge of the wind turbine blade. The spoiler is disposed on the opposing side of the body. As soon as the wind turbine blade is driven by wind, the spoiler stirs air and guides the air across two sides thereof. When guided by the spoiler, airflows turn into vortexes on the wind turbine blade; hence, the chance that the wind turbine will stall and generate noise is greatly reduced.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: February 16, 2021
    Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, R.O.C.
    Inventors: Yan-Ting Lin, Guan-Ting Lin, En-Kai Cheng, Chin-Cheng Huang
  • Patent number: 10923690
    Abstract: A refined microcrystalline electrode manufacturing method is provided. The refined microcrystalline electrode manufacturing method includes the following step. First, an active material electrode layer is subjected to a conventional thermal annealing (CTA) process in an oxygen-containing environment at a first temperature interval to form an active material crystallization precursor; the active material crystallization precursor is subjected to a rapid thermal annealing (RTA) process in the oxygen-containing environment at a second temperature interval to form an active material coating layer with uniformly distributed fine microcrystal grains, wherein the temperature range of the second temperature interval is greater than the temperature range of the first temperature interval. In addition, a thin film battery and a thin film battery manufacturing method are also provided.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: February 16, 2021
    Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, R.O.C
    Inventors: Tien-Hsiang Hsueh, Yuh-Jenq Yu, Chi-Hung Su, Der-Jun Jan
  • Patent number: 10916800
    Abstract: An apparatus is provided for plating a lithium (Li)-compound thin film. In the thin film, Li is obtained through thermal evaporation, and titanium (Ti) or other metal by using arc plasma. The elements converted into gas phase are co-deposited in a plasma environment with a reaction gas (oxygen) to be activated as excited atoms or molecules for reaction. In the end, all of the constituent elements are deposited on a substrate to form the Li-compound thin film. Thus, reaction efficiency is high with a fast deposition rate. The composition ratio of each element is independently determined to control its yield according to the requirement. Hence, the present invention greatly enhances the fabrication rate with lowered production cost for applications in the thin-film battery industries.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: February 9, 2021
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Der-Jun Jan, Yuh-Jenq Yu, Tien-Hsiang Hsueh, Tien-F Ko
  • Patent number: 10839516
    Abstract: A simulate segmentation method of cylinder and pie cake digital models utilizes a three-dimensional model and a reference point to cope with various shapes of the nuclear reactor structures. The segmentation simulation of the nuclear reactor structure is conducted with genetic algorithm. The segmentation simulation of the nuclear reactor structure is achieved by using the genetic algorithm to perform a double selection mechanism on the cross-sectional area of the nuclear reactor structure to select the optimal configuration of the segmentation, thus minimizing the cross-sectional areas of the nuclear reactor structure. The cutter segments the nuclear reactor structure based on the optimal configuration of the segmentation, thereby achieving the purpose of minimizing the attrition rate of a cutter and segmenting the nuclear reactor structure.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: November 17, 2020
    Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN
    Inventors: Yu-Hsiang Hung, Chung-Hao Huang, Shiang-Fong Chen, Po-Chou Tsai
  • Patent number: 10826101
    Abstract: A flow battery apparatus is provided with shunted currents repressed. The apparatus has a positive electrode device, a negative electrode device and a plurality of gas-gap devices. Gas-gap devices are separately set between branching channels and inlet and outlet manifolds of positive and negative electrodes. Each of the branching channels separately has an inserting tube to be inserted into one of the gas-gap devices. The diameter of the inserted vessel of gas-gap devices is bigger than the diameter of the inserting tube connected to a corresponding one of the branching channels. Thus, working liquids transferred to the positive and negative electrodes are segregated with coordination of the gas-gap devices. Only air spaces and discrete liquid drops are left between separated parts of the working liquids. Thus, shunted currents are repressed by preventing conductive paths from being formed between the positive and negative electrodes.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: November 3, 2020
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Hwei-Liang Chang, Ning-Yih Hsu, Yao-Sheng Hsu, Zone-Sure Chang
  • Patent number: D903075
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: November 24, 2020
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Yi-Ya Huang, Chun-Yi Chen, Hwen-Fen Hong