Patents Assigned to INSTITUTE
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Publication number: 20210311226Abstract: A two dimensional (2D) photonic crystal (PhC) structure includes a substrate and a periodic grating structure formed on the substrate. The periodic grating structure includes a plurality of gratings having a grating period, a. Each pair of adjacent gratings is separated by air. Each grating has a grating width, d, and includes a plurality of alternating layers of a first material and a second material. The first material corresponds to a high index material. The second material corresponds to a low index material. A ratio of a first refractive index of the first material to a second refractive index of the second material is greater than or equal to two. Each first material layer has a first thickness, t1. Each second material layer has a second thickness, t2. The 2D PhC structure has a structure refractive index at or near zero for a range of frequencies.Type: ApplicationFiled: August 1, 2019Publication date: October 7, 2021Applicant: RENSSELAER POLYTECHNIC INSTITUTEInventors: Shizhao Liu, Joel L. Plawsky
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Publication number: 20210313185Abstract: A method for etching a surface including obtaining a substrate comprising a material; reacting a surface of a substrate with a reactant, comprising a gas or a plasma, to form a reactive layer on the substrate, the reactive layer comprising a chemical compound including the reactant and the material; and wet etching or dissolving the reactive layer with a liquid wet etchant of solvent that selectively etches or dissolves the reactive layer but not the substrate.Type: ApplicationFiled: April 6, 2021Publication date: October 7, 2021Applicant: California Institute of TechnologyInventor: Harold Frank Greer
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Publication number: 20210312086Abstract: Disclosed herein are an apparatus and method for recommending privacy control. A privacy control server includes multiple common privacy control recommendation models learned based on personal information provision histories of multiple users, a user preference determination unit for generating at least one question item based on the multiple common privacy control recommendation models and determining a privacy control preference of a user based on a result of a user answer to the at least one question item, and a common privacy control recommendation model provision unit for providing a common privacy control recommendation model selected to match the privacy control preference of the user to the user.Type: ApplicationFiled: April 7, 2021Publication date: October 7, 2021Applicant: Electronics and Telecommunications Research InstituteInventors: Seung-Hyun KIM, Seok-Hyun KIM, Soo-Hyung KIM, Young-Sam KIM, Jong-Hyouk NOH, Kwan-Tae CHO, Sang-Rae CHO, Young-Seob CHO, Jin-Man CHO, Jung-Yeon HWANG
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Publication number: 20210313082Abstract: A steam generator accident mitigation system is disclosed. A steam generator accident mitigation system to mitigate an accident if the accident occurs in a steam generator installed inside a containment building of a nuclear power plant according to an exemplary embodiment of the present system, the system including: a pressurizing tank which is installed inside the containment building and includes a first cooling water and a non-condensable gas for pressurizing the first cooling water therein; at least one connecting pipe connecting the steam generator and the pressurizing tank; and at least one connecting pipe valve which is installed in the at least one connecting pipe, respectively, and is able to control the amount of opening of the connecting pipe; wherein opening of the at least one connecting pipe valve permits fluid communication between the steam generator and the pressurizing tank.Type: ApplicationFiled: December 15, 2020Publication date: October 7, 2021Applicant: KOREA ATOMIC ENERGY RESEARCH INSTITUTEInventors: Jin-Ho SONG, Kwang Soon HA, Byeonghee LEE, Sung IL KIM, Yong Mann SONG
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Publication number: 20210308268Abstract: The poly(pro-drug) material includes one or more alternating therapeutic compounds and biodegradable hydrocarbyl groups. The therapeutic compounds and biodegradable hydrocarbyl groups are separated by cleavable linker compounds. The therapeutic compounds, such as estrogen, curcumin, and fingolimod, include a plurality of substitutable functional groups that provide reaction sites for complexing with the cleavable linkers and in turn one or more polymers, such that the poly(pro-drug) material ends up composed of the therapeutic compound itself In aqueous media and at physiological temperature and pH, the poly(pro-drug) materials degrade to release the therapeutic compounds from the material with a zero-order release profile. Advantageously, the poly(pro-drug) materials release the therapeutic compounds on time scales of years. The poly(pro-drug) materials also exhibit reduced to allow for prolonged implantation within a patient.Type: ApplicationFiled: October 16, 2019Publication date: October 7, 2021Applicant: RENSSELAER POLYTECHNIC INSTITUTEInventors: Edmund Francis PALERMO, Anthony Richard D'AMATO, Ryan J. GILBERT, Samuel Ellman
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Publication number: 20210309867Abstract: A carbon nanotube aligned film as well as a preparation method and application thereof are disclosed. The preparation method includes: providing a carbon nanotube dispersion solution comprising a selected carbon nanotube, a polymer as a carbon nanotube dispersing agent and binding to the selected carbon nanotube, an aromatic molecule binding to the selected carbon nanotube and allowing the surface of the selected carbon nanotube to have the same charges and an organic solvent being at least used for cooperating with the rest components of the dispersion solution to form uniform dispersion solution; and introducing a water phase layer to the upper surface of the dispersion solution to form a double-layer liquid phase system, partially or completely inserting a base into the double-layer liquid system, and then pulling out the base so as to form the carbon nanotube aligned film on the surface of the base.Type: ApplicationFiled: October 16, 2018Publication date: October 7, 2021Applicant: SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS (SINANO), CHINESE ACADEMY OF SCIENCESInventors: Bing GAO, Song QIU, Hehua JIN, Qingwen LI
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Publication number: 20210309740Abstract: The invention is directed to a bispecific chimeric antigen receptor, comprising: (a) at least two antigen-specific targeting regions; (b) an extracellular spacer domain; (c) a transmembrane domain; (d) at least one co-stimulatory domain; and (e) an intracellular signaling domain, wherein each antigen-specific targeting region comprises an antigen-specific single chain Fv (scFv) fragment, and binds a different antigen, and wherein the bispecific chimeric antigen receptor is co-expressed with a therapeutic control. The invention also provides methods and uses of the bispecific chimeric antigen receptors.Type: ApplicationFiled: September 29, 2020Publication date: October 7, 2021Applicant: Seattle Children's Hospital d/b/a Seattle Children's Research InstituteInventor: Michael Jensen
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Publication number: 20210314399Abstract: In a multi-source hybrid overlay network including a plurality of peers, an apparatus that recovers missing data occurring in a tree recovery process, acquires data that a peer does not have in a pull method through exchanging buffer maps with a first counterpart peer connected to a primary path recovered in the tree recovery process and at least one second counterpart peer connected to at least one candidate path, and provides data that the first counterpart peer does not have to the first counterpart peer in the push method, when a data recovery policy is a pull method, is provided.Type: ApplicationFiled: February 25, 2021Publication date: October 7, 2021Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Wook HYUN, Mi Young HUH
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Publication number: 20210313766Abstract: Disclosed are a wavelength-selectable laser diode and an optical communication apparatus including the same. The wavelength-selectable laser diode includes a substrate, which includes a gain region, a tuning region spaced apart from the gain region, and a phase adjusting region between the tuning region and the gain region, a waveguide layer on the substrate, a clad layer on the waveguide layer, and gratings disposed on the substrate or the clad layer in the gain region and the tuning region.Type: ApplicationFiled: March 26, 2021Publication date: October 7, 2021Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Oh Kee KWON, Su Hwan OH, Kisoo KIM, Chul-Wook LEE
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Publication number: 20210309647Abstract: The invention provides compounds that are inhibitors or covalent modifiers of succinate dehydrogenase subunit B (SDHB) and/or inhibitors of apoptosis, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition.Type: ApplicationFiled: May 28, 2021Publication date: October 7, 2021Applicant: National Institute of Biological Sciences, BeijingInventors: Zhiyuan Zhang, Xiaodong Wang, Shaoqiang Huang, Xian Jiang, Li Li, Zhaolan Zhang, Jianguang Han
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Publication number: 20210309538Abstract: An integrated method for clearance, collection and capture of internal pollutants and algae at the bottom of a lake include the following steps: selecting areas where the pollution level is high, and organic or inorganic particulate matter is prone to accumulation and carrying out trenching operations at the bottom of the lake to form a plurality of traps; and removing the sludge and algae inside the traps and clearing the sediment inside the traps, for subsequent internal pollution control when the surface-layer sludge on both sides of the traps almost fills up the traps. This method makes use of the hydrodynamic disturbances of waves formed by natural wind energy and lake currents to continuously transport sludge with a high pollution level and a small specific gravity and algae in the surface layer of the lake bottom, which are rich in organic debris, to artificially built traps.Type: ApplicationFiled: November 11, 2020Publication date: October 7, 2021Applicant: NANJING INSTITUTE OF GEOGRAPHY & LIMNOLOGY. CHINESE ACADEMY OF SCIENCESInventors: Weiping Hu, Yihui Zhang, Jiancai Deng, Weiwei Xu
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Publication number: 20210314546Abstract: The present disclosure relates to an apparatus, method and system for generating a three-dimensional image using a coded phase mask. According to the present disclosure, an apparatus for generating a three-dimensional image, the apparatus may comprise a communicator for transmitting and receiving a signal and a processor for controlling the communicator, wherein the processor synthesizes complex data for an object based on an image, which is obtained by shooting an object, and generates a three-dimensional image of the object based on the complex data for the object and a point spread function (PSF) image for a point light source.Type: ApplicationFiled: April 2, 2021Publication date: October 7, 2021Applicant: Electronics and Telecommunications Research InstituteInventors: Ki Hong CHOI, Joong Ki PARK, Kee Hoon HONG
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Publication number: 20210314566Abstract: Disclosed herein are a method, an apparatus and a storage medium for image encoding/decoding. For efficient image compression, efficient syntax is required. Pieces of information required for image decoding may be structurally or semantically associated with each other. Based on this association, whether signaling of one piece of information is to be performed may be determined based on another piece of information. Further, based on this association, the signaling order or priority of multiple pieces of information may be determined. Depending on this determination, based on the number of subpictures present in a picture in high-level syntax, the number of slices present in the picture may be selectively signaled.Type: ApplicationFiled: March 31, 2021Publication date: October 7, 2021Applicant: Electronics and Telecommunications Research InstituteInventors: Woong LIM, Gun BANG
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Publication number: 20210309521Abstract: Provided is a method of synthesizing apatite powder by emitting a laser beam to a surface of a substrate immersed in a precursor solution. The method is including immersing a substrate in an apatite-forming precursor solution, emitting a laser beam to a region on a surface of the substrate immersed in the precursor solution, and obtaining apatite powder generated in the precursor solution.Type: ApplicationFiled: December 22, 2020Publication date: October 7, 2021Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Hojeong JEON, Seung Hoon UM, Yu Chan KIM, Hyung-Seop HAN, Myoung-Ryul OK, Hyunseon SEO, Hyun Kwang SEOK
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Publication number: 20210308648Abstract: A large capacity natural material composition conversion apparatus using a microwave with a preset pressure function includes a chamber including a sealed reaction space accommodating a material, an radiator configured to heat the material by radiating a microwave into the reaction space, a pressure regulator configured to regulate a pressure of the reaction space by supplying a gas into the reaction space, and a controller configured to control the pressure regulator and the radiator, and preliminarily increase a pressure of the reaction space by controlling the pressure regulator before heating the material.Type: ApplicationFiled: April 2, 2021Publication date: October 7, 2021Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Jungyeob HAM, Taejung KIM, Bong Chul CHUNG, Sungdo HA, Seok LEE, Young Tae PARK, Pilju CHOI
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Publication number: 20210309970Abstract: The invention features methods of identifying a hematopoietic/stem progenitor population for clinical transplantation and gene therapy, and compositions for transplantation or gene therapy featuring cells characterized as CD34+CD164High.Type: ApplicationFiled: March 26, 2021Publication date: October 7, 2021Applicants: THE CHILDREN'S MEDICAL CENTER CORPORATION, DANA-FARBER CANCER INSTITUTE, INC.Inventors: LUCA BIASCO, MARIANA LOPERFIDO, CRISTINA BARICORDI, DANILO PELLIN
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Publication number: 20210314276Abstract: Provided are a system and method for controlling a workflow across domains on the basis of a hierarchical engine framework. Inventive workflow control makes it possible to configure a flexible hierarchical engine framework and provide a workflow service with low latency. Also, the system and method make it possible to control a workflow by building an engine and a data pipeline across domains.Type: ApplicationFiled: June 16, 2021Publication date: October 7, 2021Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Tae Wan YOU, Yeon Hee LEE, Cheol Sig PYO, Yong Geun HONG, Min Suk KIM, Woong Shik YOU, Seong Ik CHO, Hyun Joong KANG, Kwi Hoon KIM, Hyun Jae KIM, Ho Sung LEE, Jung Ha HONG
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Publication number: 20210309705Abstract: Inhibitors are provided for targeting ?-secretase to reduce amyloid load as a viable strategy in Alzheimer's disease treatment and drug discovery. ?-secretase has been shown to cleave amyloid precursor protein, causing an increase in extracellular concentration of amyloid-? peptides. This extracellular concentration increase can lead to build-up amyloid plaques in patients and associated health complications for them. The inhibitors bind to a C-terminal lysine cluster adjacent the transmembrane domain of amyloid precursor protein through both covalent and non-covalent interactions. These interactions inhibit the ability of ?-secretase to cleave the amyloid precursor protein, halting the build-up of extracellular amyloid-? peptides. The inhibitors exhibit specificity for amyloid precursor proteins, reducing concerns of potential off-target effects.Type: ApplicationFiled: June 21, 2021Publication date: October 7, 2021Applicant: Rensselaer Polytechnic InstituteInventor: Chunyu WANG
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Publication number: 20210308476Abstract: Provided is a cancer treatment device which includes a first electrode and a second electrode, which are electrically connected to a signal generator and face each other with a target area therebetween, and a temperature sensor which is electrically connected to the signal generator and disposed adjacent to the target area. A cancer cell is present in the target area. The signal generator applies an AC voltage between the first electrode and the second electrode to generate an electric field between the first electrode and the second electrode. The signal generator changes an intensity of the electric field on the basis of a temperature detected from the temperature sensor. Each of the first electrode and the second electrode includes a ferroelectric material doped with manganese.Type: ApplicationFiled: March 25, 2021Publication date: October 7, 2021Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Dae-Sik LEE, Hyung Ju PARK
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Publication number: 20210310061Abstract: Disclosed herein are compositions and methods for isothermal amplification of dsDNA without the use of primers. The dis-closed compositions and methods may be used for the generation of probes used in hybrid-capture techniques that usually precede sequencing. Methods of using the probes for capturing target DNA are also provided.Type: ApplicationFiled: August 16, 2019Publication date: October 7, 2021Applicant: Dana-Farber Cancer Institute, Inc.Inventors: Gerassimos Makrigiorgos, Ka Wai Leong, Fangyan Yu