Abstract: Compounds related to acetazolamide and to its N-methyl derivatives, of the formulae: ##STR1## wherein Y is one of the following groups: ##STR2## R.sub.1 being a straight or branched alkylene or arylalkylene, or a phenylene, and the processes for their preparation; the compounds so obtained are inhibitors of carbonic anhydrase like acetazolamide but, in addition, they are well absorbed topically so that they can be used as drugs for treating glaucoma.
July 18, 1989
Date of Patent:
April 23, 1991
Instituto Chimico Internazionale Dr. Giuseppe Rende S.r.l.
Simonetta Antonaroli, Armandodariano Bianco, Mario Brufani, Giuseppe Lo Baido, Giorgio Rende