Patents Assigned to Instituto Chimico Internazionale Dr. Giuseppe Rende S.r.l.
  • Acetazolamide-related compounds, process for their preparation, and pharmaceutical composition containing the same
    Patent number: 5010204
    Abstract: Compounds related to acetazolamide and to its N-methyl derivatives, of the formulae: ##STR1## wherein Y is one of the following groups: ##STR2## R.sub.1 being a straight or branched alkylene or arylalkylene, or a phenylene, and the processes for their preparation; the compounds so obtained are inhibitors of carbonic anhydrase like acetazolamide but, in addition, they are well absorbed topically so that they can be used as drugs for treating glaucoma.
    Type: Grant
    Filed: July 18, 1989
    Date of Patent: April 23, 1991
    Assignee: Instituto Chimico Internazionale Dr. Giuseppe Rende S.r.l.
    Inventors: Simonetta Antonaroli, Armandodariano Bianco, Mario Brufani, Giuseppe Lo Baido, Giorgio Rende