Patents Assigned to InterVet, Inc.
  • Patent number: 10806698
    Abstract: A composition for oral administration of a bioactive agent to aquatic or terrestrial species includes particles each of which includes a bioactive agent dispersed in oil droplets, the oil droplets being dispersed in a matrix including an enteric coating polymer, wherein the particles each further include a mucoadhesive polymer. Methods of making and using the composition are also provided.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: October 20, 2020
    Assignee: Intervet Inc.
    Inventors: Moti Harel, Swetha Kambalapally
  • Publication number: 20200323971
    Abstract: The present invention relates to an improved vaccine against Coccidiosis in poultry. The vaccine comprises live Eimeria oocysts in a composition with relatively high viscosity because of the inclusion of between 0.3 and 1.5% w/v Xanthan gum. Upon spray vaccination the new vaccine forms beads that are quickly ingested by the birds and which provide a rapid vaccine take, resulting in a quick and effective improvement of the signs of Coccidiosis upon challenge infection. Also the invention relates to a method for the heat sterilisation of a composition comprising Xanthan gum; by the inclusion of a concentration of a metal salt, an irreversible and dramatic reduction in viscosity can be largely prevented.
    Type: Application
    Filed: June 26, 2020
    Publication date: October 15, 2020
    Applicant: Intervet Inc.
    Inventor: Colin Crouch
  • Publication number: 20200323975
    Abstract: The present invention relates to vaccination against animal pathogens using alphavirus-replicon RNA particles and oil adjuvants. To a vaccine, and a kit of parts comprising the replicon particles and the oil adjuvant. Also to methods and uses of making and using the vaccine and the components of the kit.
    Type: Application
    Filed: December 3, 2018
    Publication date: October 15, 2020
    Applicant: Intervet Inc.
    Inventors: Mark A. Mogler, Erin Strait, Ruud Philip Antoon Maria Segers
  • Publication number: 20200323978
    Abstract: The present invention discloses novel recombinant multivalent non-pathogenic Marek's Disease virus constructs that encode and express foreign antigens from three or more avian viruses, along with methods of the use of the multivalent poultry virus vaccines.
    Type: Application
    Filed: October 11, 2018
    Publication date: October 15, 2020
    Applicant: Intervet Inc.
    Inventors: Stephanie M. COOK, Mohamad MORSEY, Ian TARPEY
  • Patent number: 10799483
    Abstract: The present invention relates to methods of treating demodicosis by administering an isoxazoline compound of formula (I)
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: October 13, 2020
    Assignee: Intervet Inc.
    Inventors: Heike Williams, Anja Regina Heckeroth, Janina Tanzler, Regis Joel Alain Frenais
  • Publication number: 20200299726
    Abstract: The present invention relates to the field of veterinary vaccines, in particular to porcine vaccines against PCV2 and associated diseases. Specifically the invention relates to the finding that a mutation is required in PCV2b ORF2 protein, to prevent its nuclear accumulation upon expression in insect cells; the mutation introduces a Proline at amino acid position 131. This allows efficient expression in insect cells, easy harvesting, and generates large amounts of virus-like particles. The VLPs are highly effective in vaccines for porcines for reduction of infection by PCV2 or of associated signs of disease.
    Type: Application
    Filed: October 16, 2018
    Publication date: September 24, 2020
    Applicant: Intervet Inc.
    Inventors: Paulus Jacobus Antonius SONDERMEIJER, Lisette SANDERS, Karin Huberdina Antonia VAN DER HEIJDEN-LIEFKENS
  • Publication number: 20200288679
    Abstract: A method for external fish parasites, such as sea lice, monitoring in aquaculture, comprising the steps of: —submerging a camera (52) in a sea pen (40) comprising fish (72, 74); —capturing images of the fish (72, 74) with the camera (52); and —identifying external fish parasites such as sea lice on the fish (72, 74) by analyzing the captured images, characterized by the steps of: —distinguishing between at least two different classes of external fish parasites such as sea lice which differ in the difficulty of recognizing the external fish parasites such as sea lice; —calculating quality metrics for each captured image, the quality metrics permitting to identify the classes of external fish parasites such as sea lice for which the quality of the image is sufficient for sea lice detection; and —establishing separate detection rates for each class of sea lice, each detection rate being based only on images the quality of which, as described by the quality metrics, was sufficient for detecting external fish para
    Type: Application
    Filed: December 19, 2018
    Publication date: September 17, 2020
    Applicant: Intervet Inc.
    Inventors: Russel Howe, Zachary Lizer, James Wallace Sarrett, Peter Jon Abrahamson, Jascha Tucker Little
  • Publication number: 20200288680
    Abstract: A method for external fish parasite monitoring in aquaculture, comprising the steps of: submerging a camera in a sea pen comprising fish; capturing images of the fish with the camera; and identifying external fish parasite on the fish by analyzing the captured images, characterized by the steps of: distinguishing between at least two different classes of external fish parasite which differ in the difficulty of recognizing the external fish parasite; calculating quality metrics for each captured image, the quality metrics permit-ting to identify the classes of external fish parasite for which the quality of the image is sufficient for lice detection.
    Type: Application
    Filed: December 19, 2018
    Publication date: September 17, 2020
    Applicant: Intervet Inc.
    Inventors: Russel Howe, Zachary Lizer, James Wallace Sarrett, Peter Jon Abrahamson, Jascha Tucker Little
  • Publication number: 20200289634
    Abstract: The present invention provides a vaccine for canine Lyme disease and methods of making and using the vaccine alone, or in combinations with other protective agents.
    Type: Application
    Filed: December 3, 2018
    Publication date: September 17, 2020
    Applicant: Intervet Inc.
    Inventors: Rhonda LaFleur, Jennifer C. Dant, Mark A. Mogler, Steven M. Callister, Zhichang Xu
  • Publication number: 20200288678
    Abstract: A system for external fish parasite monitoring in aquaculture, the system comprising: —a camera (52) suitable to be submerged in a sea pen suitable for containing fish, the camera being arranged for capturing images of the fish; and —an electronic image processing system (86) configured for identifying external fish parasites on the fish by analyzing the captured images, characterized by a camera and lighting rig (10) having a vertical support member (14), an upper boom (16) articulated to a top end of the support member (14) and carrying an upper lighting array (22), a lower boom (18) articulated to a lower end of the support member (14) and carrying a lower lighting array (24), and a housing (20) attached to the support member and carrying the camera (52), wherein the upper and lower lighting arrays (22, 44) are configured to illuminate, from above and from below, a target region inside a field of view of the camera (52).
    Type: Application
    Filed: December 19, 2018
    Publication date: September 17, 2020
    Applicant: Intervet Inc.
    Inventors: Russel Howe, Zachary Lizer, James Wallace Sarrett, Peter Jon Abrahamson, Jascha Tucker Little
  • Publication number: 20200283389
    Abstract: An improved process for producing a compound of Formula (I).
    Type: Application
    Filed: December 22, 2016
    Publication date: September 10, 2020
    Applicant: Intervet Inc.
    Inventors: Michael Berger, Hans Peter Niedermann, Tobias Kappesser, Stephan Veit, Heiko Bothe, Marcus Knell, Christophe Pierre Alain Chassaing
  • Patent number: 10758601
    Abstract: The present invention relates to the fields of veterinary parasitology and -vaccinology; more specifically the invention relates to a composition comprising live Eimeria oocysts and a pharmaceutically acceptable carrier. The composition is characterised in that it comprises a TLR3 agonist. The composition can be used to prepare a vaccine for poultry against Coccidiosis. The vaccine can be applied for example as a coarse spray on day-old chicks. The TLR3 agonist in the vaccine allows for a reduction of the dose of Eimeria oocysts up to 4 fold, while obtaining the same level of protection against challenge as from a vaccine without the TLR3 agonist. Alternatively, when employing a conventional dose of Eimeria oocysts in the vaccine, the TLR3 agonist causes an earlier onset of immunity, resulting in a significant reduction of the intestinal lesion score upon challenge, already at 2 instead of at 3 weeks after vaccination.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: September 1, 2020
    Assignee: Intervet Inc.
    Inventors: Alex Shepherd, Colin Crouch
  • Patent number: 10751405
    Abstract: The present invention pertains to a vaccine comprising non live Lawsonia intracellularis antigen and a pharmaceutically acceptable carrier for use in a method to reduce in a pig the negative impact on average daily weight gain (ADWG) associated with subclinical infection with Lawsonia intracellularis, by systemic administration of the vaccine to the pig.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: August 25, 2020
    Assignee: Intervet Inc.
    Inventor: Antonius Arnoldus Christiaan Jacobs
  • Patent number: 10751403
    Abstract: The present invention pertains to a vaccine comprising an IgM protease antigen of Streptococcus suis, for use in a method wherein a female pig is vaccinated in order to protect a piglet against Streptococcus suis through the intake of colostrum of the vaccinated female pig.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: August 25, 2020
    Assignee: Intervet Inc.
    Inventor: Antonius Arnoldus Christiaan Jacobs
  • Publication number: 20200254088
    Abstract: The present invention provides new multivalent vaccines for felines. The present invention also provides methods of making and using the multivalent vaccines alone or in combinations with other protective agents.
    Type: Application
    Filed: November 5, 2018
    Publication date: August 13, 2020
    Applicant: Intervet Inc.
    Inventors: Zhichang Xu, Rhonda LaFleur, Ian Tarpey
  • Publication number: 20200237727
    Abstract: The present invention relates to methods of treating or preventing arthropod infestations of poultry animals and methods of controlling arthropod infestations in poultry animal's environment by administering an isoxazoline compound of formula (I) via drinking water.
    Type: Application
    Filed: April 15, 2020
    Publication date: July 30, 2020
    Applicant: Intervet Inc.
    Inventors: Anja Regina Heckeroth, Hartmut Zoller, Annie Flochlay-Sigognault, Bruno Huyghe
  • Patent number: 10711061
    Abstract: The present invention discloses antibodies to canine PD-1 that have specific sequences and a high binding affinity for canine PD-1. The invention also discloses the use of the antibodies of the present invention in the treatment of cancer in dogs.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: July 14, 2020
    Assignee: Intervet Inc.
    Inventors: Mohamad Morsey, Yuanzheng Zhang, Denise Bartels-Morozov, Jason Erskine, Ian Tarpey
  • Publication number: 20200206340
    Abstract: The present invention pertains to a vaccine comprising an ORF2 encoded protein of porcine circo virus 2 (PCV2) and a pharmaceutically acceptable carrier, for use in a method to protect a pig against an infection with porcine circo virus type 2 by administering the vaccine to the pig, wherein the vaccine comprises less than 20 ?g per dose of the ORF2 encoded protein, the protein being of a porcine circo virus of genotype 2b.
    Type: Application
    Filed: August 2, 2018
    Publication date: July 2, 2020
    Applicant: Intervet Inc.
    Inventors: Melanie SNO, Erik COX, Ruud Philip Antoon Maria SEGERS
  • Publication number: 20200206336
    Abstract: The present invention pertains to a vaccine comprising an IgM protease antigen of Streptococcus suis, for use in a method for protecting piglets having maternally derived anti-Streptococcus suis antibodies against Streptococcus suis, by administering the vaccine to the piglets at an age of at most 28 days, preferably before the piglets are weaned.
    Type: Application
    Filed: August 2, 2018
    Publication date: July 2, 2020
    Applicant: Intervet Inc.
    Inventor: Antonius Arnoldus Christiaan JACOBS
  • Patent number: 10689612
    Abstract: The invention pertains to a method to purify coccidial oocysts having dimensions between Dmin and Dmax from faeces comprising the steps of collecting the faeces containing the coccidial oocysts from host animals, diluting the faeces in an aqueous medium, separating a coarse fraction comprising macroscopic particulate matter from the diluted faeces and collecting an aqueous fraction containing the oocysts, characterised in that the method further comprises sieving the aqueous fraction over a first sieve deck having mesh openings to let the oocysts pass, to obtain an aqueous filtrate comprising the oocysts and a first residue comprising particles larger than the oocysts, and sieving the aqueous filtrate over a second sieve deck having mesh openings to obstruct passing of the oocysts through this sieve deck, to obtain a second residue comprising the purified oocysts and a waist filtrate comprising particles smaller than the oocysts.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: June 23, 2020
    Assignee: Intervet Inc.
    Inventors: Koen Gevers, Theodorus Petrus Maria Schetters