Patents Assigned to Iowa State University Research Foundation, Inc.
  • Patent number: 10844166
    Abstract: The present invention relates to a thermoplastic copolymer, block copolymer, and statistical copolymer comprising plural acrylated polyol monomeric units having different degrees of acrylation of hydroxyl groups. The acrylated polyol monomeric units have an average degree of acrylation greater than 1 and less than the number of the hydroxyl groups of the polyol. The present invention also relates to a method of making the thermoplastic copolymer, block copolymer, and statistical copolymer, and using them in various applications, such as asphalt rubber modifiers, adhesives, or an additive in a fracking fluid for oil fracking.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: November 24, 2020
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Eric W. Cochran, R. Christopher Williams, Nacu Hernandez, Elvira Joana Ferreira Peralta, Michael John Forrester
  • Patent number: 10844031
    Abstract: The present application relates to a process for preparation of a compound of Formula (I) and Formula (IV): wherein is as described herein; and wherein and R are as described herein.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: November 24, 2020
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Aaron David Sadow, Zachary Benjamin Weinstein, George A. Kraus
  • Patent number: 10837045
    Abstract: Various embodiments disclosed relate to a sensor assembly probe for determining enzymatic activity. The sensor assembly probe includes one or more fluorescent hydrophobic semi-conductive nanoparticles disposed in an aqueous medium. The assembly further includes an amphiphilic polymer including a substrate for a predetermined enzyme. The amphiphilic polymer coats at least a portion of a surface of the fluorescent hydrophobic semi-conductive nanoparticle.
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: November 17, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Nigel Forest Reuel, Nathaniel Kallmyer
  • Patent number: 10835959
    Abstract: A concentric ring gas atomization nozzle with isolated gas supply manifolds is provided for manipulating the close-coupled atomization gas structure to improve the yield of atomized powders.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: November 17, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Joel R. Rieken, Andrew J. Heidloff, Iver E. Anderson
  • Patent number: 10823630
    Abstract: We present a microelectromechanical system (MEMS) graphene-based pressure sensor realized by transferring a large area, few-layered graphene on a suspended silicon nitride thin membrane perforated by a periodic array of micro-through-holes. Each through-hole is covered by a circular drum-like graphene layer, namely a graphene “microdrum”. The uniqueness of the sensor design is the fact that introducing the through-hole arrays into the supporting nitride membrane allows generating an increased strain in the graphene membrane over the through-hole array by local deformations of the holes under an applied differential pressure. Further reasons contributing to the increased strain in the devised sensitive membrane include larger deflection of the membrane than that of its imperforated counterpart membrane, and direct bulging of the graphene microdrum under an applied pressure. Electromechanical measurements show a gauge factor of 4.4 for the graphene membrane and a sensitivity of 2.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: November 3, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Liang Dong, Qiugu Wang, Wei Hong
  • Patent number: 10804563
    Abstract: An ion conductivity mixed chalcogenide (e.g. oxy-sulfide), mixed network former solid electrolyte is provided for use in solid state batteries.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: October 13, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventor: Steve W. Martin
  • Patent number: 10793673
    Abstract: The present invention relates to a polymer comprising a repeating group having the structure of formula (I) wherein R, R1, R2, R3, R4, X, and s are as described herein and salt thereof. Also disclosed is a process of synthesizing such polymers.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: October 6, 2020
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Nacu Hernandez, Mengguo Yan, Eric W. Cochran, John Edward Matthiesen, Jean-Philippe Tessonnier
  • Patent number: 10792421
    Abstract: This invention relates to automatic insulin delivery systems and methods of administering insulin. Preferably the systems and methods comprise a predictive feedforward control.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: October 6, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Derrick K. Rollins, Sr., Yong Mei
  • Patent number: 10792508
    Abstract: Provided herein are embodiments of a Quadruple Butterfly Coil (QBC) configuration having enhanced focality for stimulation of specific areas of a brain for therapeutic treatment. Finite element simulations were conducted for the QBC, the QBC with a single shield, and the QBC with a double shield. The stimulation profiles for these coil configurations were assessed with 50 anatomically realistic MRI derived head models. The coils were positioned on the vertex and the scalp over the dorsolateral prefrontal cortex to stimulate the brain. Computer modeling of the coils was performed to determine volume of stimulation, maximum electric field, location of maximum electric field, and area of stimulation across all 50 head models for both coils.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: October 6, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Priyam Rastogi, Erik Gordon Lee, Magundappa Ravi L. Hadimani, David C. Jiles
  • Patent number: 10787672
    Abstract: The present disclosure includes methods and components for production of valuable industrial compounds in yeast. In an embodiment, the present invention provides a nucleic acid construct with increased stability for gene expression or gene editing comprising: a nucleic acid sequence encoding one or more of SEQ ID NO: 1-8 (CENs 1-8); and one or more regulatory elements functional in a yeast cell. In an embodiment of the present invention the nucleic acid constructs are vectors, preferably episomal vectors. High expression promoters, as well as methods for increasing production of compounds such as aromatics are disclosed.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: September 29, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Zengyi Shao, Mingfeng Cao, Miguel Suastegui, Meirong Gao
  • Patent number: 10788384
    Abstract: A method, apparatus, and system to quantify tension forces of the anchor bolts for, e.g., SLTS support structures. A sensing assembly comprising one or more washers is installed along an anchor bolt. The sensing assembly comprises two spaced-apart surfaces between which a capacitance can be measured if electrical potential is created between the surfaces. The capacitance between the surfaces can be calibrated to bolt tension based on the relative distance between the surfaces. An RFRD circuit is connected to the two surfaces. An RF interrogation signal can supply the electrical potential and allow a reading of the responsive capacitance between surfaces to convert the capacitance reading into a bolt tension. Additionally, the introduction of the battery-free RFRD allows data to be acquired wirelessly from a distance, enabling an entirely new method of inspection. With minimum additional hardware cost, it provides a cost-effective way to replace traditional bolt installation and inspection methods.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: September 29, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: An Chen, Daji Qiao, Long Que
  • Patent number: 10782193
    Abstract: An example apparatus can comprise an emitter to emit radio frequency radiation, an absorber that changes temperature based on emissions from the emitter, and one or more sensors to measure a temperature difference between a sample and a reference coupled to the absorber.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: September 22, 2020
    Assignees: UT-Battelle, LLC, Iowa State University Research Foundation, Inc.
    Inventors: Tom Byvank, Benjamin S. Conner, Roger A. Kisner, Michael A. McGuire, Orlando Rios, Michael S. Kesler, Gerard M. Ludtka, Boyd Evans, Cajetan Ikenna Niebedim, Ralph William McCallum
  • Patent number: 10766831
    Abstract: A method for gas atomization of oxygen-reactive reactive metals and alloys wherein the atomized particles are exposed as they solidify and cool in a very short time to multiple gaseous reactive agents for the in-situ formation of a protective reaction film on the atomized particles. The present invention is especially useful for making highly pyrophoric reactive metal or alloy atomized powders, such as atomized magnesium and magnesium alloy powders. The gaseous reactive species (agents) are introduced into the atomization spray chamber at locations downstream of a gas atomizing nozzle as determined by the desired powder or particle temperature for the reactions and the desired thickness of the reaction film.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: September 8, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Iver E. Anderson, Andrew D. Steinmetz, David J. Byrd
  • Patent number: 10758984
    Abstract: A physical and chemical method is provided for de-mixing (e.g. extracting, separating, purifying and/or enriching) the metal constituents of an alloy or mixed material into different droplet or solid particle products that are highly enriched in the respective phases of the metal. The method involves for instance but is not limited to, shearing, separating and segregating metallic droplets and particles in a carrier fluid to form other droplets or particles that are each separately highly enriched in one of some, if not of all, of the constituent phases of the alloy or mixed material.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: September 1, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Martin M. Thuo, Jacob Sporrer, Christophe Frankiewicz
  • Patent number: 10759127
    Abstract: A composite material is provided including a polymer matrix and undercooled liquid metallic core-shell particles disposed in the matrix, wherein the particles each have an outer shell and a liquid metallic material as a core contained within the outer shell. The outer shell is frangible such that the liquid metallic material is released from at least some of the particles in response to a mechanical load applied to the composite and solidifies in-situ in the polymer matrix. As a result, the composite material can be self-strengthening and self-healing and can be reconfigurable in shape at ambient temperature.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: September 1, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Martin Thuo, Boyce S. Chang
  • Patent number: 10752711
    Abstract: The present invention relates to a thermoplastic block copolymer comprising at least one PA block and at least one PB block. The PA block represents a polymer block comprising one or more units of monomer A, and the PB block represents a polymer block comprising one or more units of monomer B. Monomer A is a vinyl, acrylic, diolefin, nitrile, dinitrile, acrylonitrile monomer, a monomer with reactive functionality, or a crosslinking monomer. Monomer B is a radically polymerizable triglyceride or mixtures thereof, typically in the form of a plant or animal oil. The present invention also relates to a method of preparing a thermoplastic block copolymer or novel thermoplastic statistical copolymers by polymerizing a radically polymerizable monomer with a radically polymerizable triglyceride or mixtures thereof via reversible addition-fragmentation chain-transfer polymerization (RAFT), in the presence of an free radical initiator and a chain transfer agent.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: August 25, 2020
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Eric W. Cochran, Ronald Christopher Williams, Nacu Hernandez, Andrew Cascione
  • Patent number: 10730975
    Abstract: The present invention relates to a thermoplastic block copolymer comprising at least one PA block and at least one PB block. The PA block represents a polymer block comprising one or more units of monomer A, and the PB block represents a polymer block comprising one or more units of monomer B. Monomer A is a vinyl, acrylic, diolefin, nitrile, dinitrile, acrylonitrile monomer, a monomer with reactive functionality, or a crosslinking monomer. Monomer B is a radically polymerizable triglyceride or mixtures thereof, typically in the form of a plant or animal oil. The present invention also relates to a method of preparing a thermoplastic block copolymer or novel thermoplastic statistical copolymers by polymerizing a radically polymerizable monomer with a radically polymerizable triglyceride or mixtures thereof via reversible addition-fragmentation chain-transfer polymerization (RAFT), in the presence of an free radical initiator and a chain transfer agent.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: August 4, 2020
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Eric W. Cochran, Ronald Christopher Williams, Nacu Hernandez, Andrew Cascione
  • Patent number: 10725373
    Abstract: A technique, and its applications, for high resolution, rapid, and simple nanopatterning. The general method has been demonstrated in several forms and applications. One is patterning nanophotonic structures at an optical fiber tip for refractive index sensing. Another is patterning nanoresonator structures on a sensor substrate for plasmonic effect related detection of VOCs. In the latter example, a graphene oxide coated plasmonic crystal as a gas sensor capable of identifying different gas species using an array of such structures. By coating the surface of multiple identical plasmonic crystals with different thicknesses of Graphene-Oxide (GO) layer, the effective refractive index of the GO layer on each plasmonic crystal is differently modulated when exposed to a specific gas. Identification of various gas species is accomplished using pattern recognition algorithm.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: July 28, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Ratnesh Kumar, Shawana Tabassum, Liang Dong
  • Publication number: 20200192969
    Abstract: Disclosed herein are embodiments of methods for encoding, decoding, and matching patterns in collections of signals. These methods use weighting functions to scale the signals. This scaling enables the use of signals of arbitrary duration, wherein the signals may include discrete sequences and spike trains. In the most general case, the signals can be represented using functionals, which extends the expressive power of the methods. Further disclosed herein are embodiments of a system that performs these methods.
    Type: Application
    Filed: August 24, 2018
    Publication date: June 18, 2020
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Alexander Stoytchev, Volodymyr Sukhoy
  • Patent number: 10667515
    Abstract: (S)-5-ethynyl-anabasine and derivatives thereof; composition comprising same and a carrier; methods of treating an animal; method of protecting a plant from a pest; and methods of making compound and derivatives.
    Type: Grant
    Filed: July 16, 2017
    Date of Patent: June 2, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Richard J. Martin, Alan P. Robertson, Brett VanVeller, Xiangwei Du, Fudan Zheng