Patents Assigned to Iowa State University Research Foundation, Inc.
  • Patent number: 11364542
    Abstract: A physical and chemical method is provided for de-mixing (e.g. extracting, separating, purifying and/or enriching) the metal constituents of an alloy or mixed material into different droplet or solid particle products that are highly enriched in the respective phases of the metal. The method involves for instance but is not limited to, shearing, separating and segregating metallic droplets and particles in a carrier fluid to form other droplets or particles that are each separately highly enriched in one of some, if not of all, of the constituent phases of the alloy or mixed material.
    Type: Grant
    Filed: July 9, 2020
    Date of Patent: June 21, 2022
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Martin Thuo, Jacob Sporrer, Christophe Frankiewicz
  • Patent number: 11357803
    Abstract: The present invention is directed to synbiotic compositions of probiotic strains and prebiotics, along with uses thereof for targeted human and animal applications, for example, in promoting health and well-being and/or treating therapeutic conditions. The present invention is also directed to methods of probiotic selection and detection of strains with the ability to produce neurochemicals in the gastrointestinal tract of a subject, providing a microbial endocrinology-based mechanism and approach for optimization of synbiotic delivery of a probiotic with a neurochemical precursor. Still further the present invention is directed to industrial applications for production of dopamine utilizing methods and media suitable for the same.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: June 14, 2022
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Mark Lyte, Daniel Nicholas Villageliu
  • Patent number: 11353435
    Abstract: A gas chromatographic (GC) column using a zwitterionic compound and methods of use thereof are disclosed herein. The volatile free acids were observed to strongly retain on these zwitterionic compounds-based columns with excellent peak symmetry. By carefully tuning the structures of these zwitterionic compounds, different selectivity toward volatile free acids was demonstrated. These stationary phases possess a wide working range with thermal stabilities at higher temperatures.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: June 7, 2022
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Jared L. Anderson, Kosuke Kuroda, He Nan
  • Patent number: 11332751
    Abstract: The present disclosure includes methods and components for production of valuable industrial compounds in yeast. In an embodiment, the present invention provides a nucleic acid construct with increased stability for gene expression or gene editing comprising: a nucleic acid sequence encoding one or more of SEQ ID NO: 1-8 (CENs 1-8); and one or more regulatory elements functional in a yeast cell. In an embodiment of the present invention the nucleic acid constructs are vectors, preferably episomal vectors. High expression promoters, as well as methods for increasing production of compounds such as aromatics are disclosed.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: May 17, 2022
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Zengyi Shao, Mingfeng Cao, Miguel Suastegui, Meirong Gao
  • Patent number: 11321537
    Abstract: A biologically-inspired model for sequence representation, method of construction and application of such models, and systems incorporating same are provided. The model captures the statistical nature of sequences and uses that for sequence encoding, recognition, and recall. The model can be trained in real time, has few tunable parameters, and is highly parallelizable, which ensures that it can scale up to very large problems. Applications of the model to word and speech recognition, machine leaning, robotics, computational bioinformatics, genetics datasets, and other sequence processing pipelines are provided.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: May 3, 2022
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Alexander Stoytchev, Volodymyr Sukhoy
  • Patent number: 11319281
    Abstract: This invention relates to a wax composition comprising a plurality of fatty acid amide compounds having the Formula (I): where R1, R2, n1, n2, m1, and m2 are as described herein. This invention also relates to a wax composition comprising: a) one or more fatty acid amide compounds having the Formula (II): and b) one or more fatty acid amide compounds having the Formula (III): where R1, R2, n1, and n2 are as described herein. This invention also relates to a fatty acid amide compound having the Formula (I) and a process for preparing a compound of Formula (I).
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: May 3, 2022
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Tong Wang, Tao Fei
  • Patent number: 11312931
    Abstract: A belt for an algal growth system includes a flexible sheet material configured to facilitate growth of a biofilm. The flexible sheet material is mounted on a first frame in a first mounted geometry, the flexible sheet material having a substantially vertical orientation when mounted on the first frame such that a first height of the first mounted geometry is greater than a first width of the first mounted geometry, the flexible sheet material being in contact with a contacting liquid.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: April 26, 2022
    Assignees: Gross-Wen Technologies, Inc., Iowa State University Research Foundation, Inc.
    Inventors: Martin Anthony Gross, Zhiyou Wen
  • Patent number: 11289248
    Abstract: A magnetocaloric material comprising a La—Fe—Si based alloy composition that is compositionally modified to include a small but effective amount of at least one of Al, Ga, and In to improve mechanical stability of the alloy (substantially reduce alloy brittleness), improve thermal conductivity, and preserve comparable or provide improved magnetocaloric effects. The alloy composition may be further modified by inclusion of at least one of Co, Mn, Cr, and V as well as interstitial hydrogen.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: March 29, 2022
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Arjun K. Pathak, Yaroslav Mudryk, Oleksandr Dolotko, Vitalij K. Pecharsky
  • Patent number: 11274294
    Abstract: Materials and methods related to gene targeting (e.g., gene targeting with transcription activator-like effector nucleases; “TALENS”) are provided.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: March 15, 2022
    Assignees: Regents of the University of Minnesota, Iowa State University Research Foundation Inc.
    Inventors: Daniel F. Voytas, Adam J. Bogdanove, Feng Zhang
  • Patent number: 11274114
    Abstract: The present invention provides mito-metformin compounds, pharmaceutical compositions thereof, and methods of using the mito-metformin compounds in the treatment of cancer.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: March 15, 2022
    Assignees: The Medical College of Wisconsin, Inc., AIX-Marseille Universite, Iowa State University Research Foundation, Inc.
    Inventors: Balaraman Kalyanaramn, Micael J. Hardy, Marcos Lopez, Olivier Ouari, Jacek Michal Zielonka
  • Patent number: 11261455
    Abstract: The present invention provides plant virus vectors developed from the Sugarcane mosaic virus (SCMV). The vectors include a nucleic acid sequence encoding an infectious Sugarcane mosaic virus (SCMV) operably linked to one or more regulatory elements functional in a plant. The plant virus vectors may be used to infect monocot plants, such as maize, for gene expression applications.
    Type: Grant
    Filed: May 18, 2020
    Date of Patent: March 1, 2022
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: John Hemmingson Hill, Steven Alan Whitham, Yu Mei, Chunquan Zhang
  • Patent number: 11259515
    Abstract: A computing system includes image receiving logic configured to receive image data indicative of an image of a field, ground identification logic configured to identify a first image portion of the image representing ground in the field, image segmentation logic configured to identify a remaining image portion that omits the first image portion from the image, and crop classification logic configured to apply a crop classifier to the remaining image portion and identify a second image portion of the image that represents locations of crop plants in the field. The computing system also includes weed identification logic configured to identify locations of weed plants in the field based on the identification of the first and second image portions and control signal generation logic configured to generate a machine control signal based on the identified locations of the weed plants.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: March 1, 2022
    Assignees: Deere & Company, IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Tarik Loukili, Timothy A. Bigelow
  • Patent number: 11248076
    Abstract: The present invention relates to a homopolymer, copolymer, block copolymer, and statistical copolymer comprising plural polyol monomeric units. The polyol monomeric units being acrylated and acylated or acetalized. The acrylated and acylated or acetalized polyol monomeric units have an average degree of acrylation which is 1 or more, but less than the number of the hydroxyl groups of the polyol and have an average degree of acylation or acetalization which is 1 or more, but less than the number of the hydroxyl groups of the polyol. The present invention also relates to a method of making the homopolymers, copolymers, block copolymers, and statistical copolymers, and using them in various applications, such as asphalt rubber modifiers, adhesives, or an additive in a fracking fluid for oil fracking.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: February 15, 2022
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Eric W. Cochran, Nacu Hernandez, Michael Forrester, Shailja Goyal, Austin Hohmann
  • Patent number: 11241678
    Abstract: A method for making organo-metal material involves providing a metal ion source in a medium that removes metal ions from the source and forms 1D metal-containing coordination polymers that self-assemble and precipitate as at least one of a 2D and 3D coordination polymer material that can be thermally treated to produce a porous metal oxide material.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: February 8, 2022
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Martin M. Thuo, Boyce S. Chang, Jiahao Chen, Aaron J. Rossini
  • Patent number: 11242459
    Abstract: The present invention relates to an asphalt product that comprises an asphalt component and a plurality of pellets comprising a mixture of a ground tire rubber and an elastomeric polymer, where the density difference between the asphalt component and the plurality of pellets is less than 10%. The present invention further relates to a pellet comprising a ground tire rubber (“GTR”) and an elastomeric polymer mixed with the GTR, where the GTR has a density of less than 1.12 g/cm3. Also disclosed are methods of producing improved asphalt and paving a surface.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: February 8, 2022
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Eric W. Cochran, Nacu Hernandez, Ronald Christopher Williams
  • Publication number: 20220022498
    Abstract: The disclosure provides for compositions and methods for the preservation of meat substitutes containing plant heme protein. In particular, small molecules that can fit in the unique heme pocket of plant heme proteins are provided to stabilize and preserve meat substitutes the products.
    Type: Application
    Filed: October 6, 2021
    Publication date: January 27, 2022
    Applicants: Wisconsin Alumni Research Foundation, Iowa State University Research Foundation, Inc.
    Inventors: Mark P. RICHARDS, Mark HARGROVE, Nantawat TATIYABORWORNTHAM, Jie YIN, Wenjing ZHANG
  • Patent number: 11220730
    Abstract: Undercooled liquid metallic core-shell particles, whose core is stable against solidification at ambient conditions, i.e. under near ambient temperature and pressure conditions, are used to join or repair metallic non-particulate components. The undercooled-shell particles in the form of nano-size or micro-size particles comprise an undercooled stable liquid metallic core encapsulated inside an outer shell, which can comprise an oxide or other stabilizer shell typically formed in-situ on the undercooled liquid metallic core. The shell is ruptured to release the liquid phase core material to join or repair a component(s).
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: January 11, 2022
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Martin Thuo, Ian Tevis
  • Patent number: 11214714
    Abstract: The present invention relates to an adhesive comprising a thermoplastic polyacrylated glycerol polymer, water, and a cross linker that is reactive with the polyacrylated glycerol polymer. This adhesive is useful in the formation of cellulosic products including oriented strand board (OSB), particle board, oriented structural straw board, chipboard, plywood, laminated veneer lumber (LVL), pressed wood, glued laminated timber (glulam), cross-laminated timber (CLT), and other wood products. Methods of producing the adhesive and cellulosic products are also disclosed.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: January 4, 2022
    Assignees: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC., MIDWEST ACRYLATED PROCESSES, LLC
    Inventors: Eric W. Cochran, Nacu B. Hernandez, R. Chris Williams, Michael Forrester, David Grewell, Andrew Becker, Joseph J. Marcinko
  • Patent number: 11208334
    Abstract: A method embodiment involves preparing single metal or mixed transition metal chalcogenide using exfoliation of two or more different bulk transition metal dichalcogenides in a manner to form an intermediate hetero-layered transition metal chalcogenide structure, which can be treated to provide a single-phase transition metal chalcogenide.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: December 28, 2021
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Viktor Balema, Ihor Hlova, Vitalij K. Pecharsky
  • Publication number: 20210397674
    Abstract: Embodiments of the present disclosure describe an efficient O(n log n) method that implements the Inverse Chirp Z-Transform (ICZT). This transform is the inverse of the well-known forward Chirp Z-Transform (CZT), which generalizes the fast Fourier transform (FFT) by allowing the sampling points to fall on a logarithmic spiral contour instead of the unit circle. Thus, the ICZT can be viewed as a generalization of the inverse fast Fourier transform (IFFT).
    Type: Application
    Filed: May 7, 2021
    Publication date: December 23, 2021
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Volodymyr Sukhoy, Alexander Stoytchev