Abstract: The present invention is directed to sulfated oligosaccharides having 4, 5 or 6 saccharidic units and wherein a glycosidic bond between two saccharide units is substituted by a C—C bond, and wherein the sulfation degree expressed as percentage of OH groups substituted by a OSO3? group is comprised between 50 and 100%. The sulfated oligosaccharides according to the invention are useful as a drug, in particular in the treatment of angiogenesis, metastasis, and inflammation.
Type:
Application
Filed:
July 9, 2009
Publication date:
September 13, 2012
Applicant:
Istituto Scientifico Di Chimica E Biochimica "G" R
Inventors:
Giangiacomo Torri, Elena Vismara, Israel Vlodavsky, Annamaria Naggi