Abstract: Provided are amino acid based polymerizable compounds and their applications in ophthalmic devices. The amino acid based polymerizable compounds are of formula I: wherein R, R1, and R2 are as described herein.

Abstract: A device and method for selectively applying a composition to a treatment surface (e.g., skin) to alter an aesthetic appearance of the skin in the undereye region of the face. The device includes an applicator applying the composition to the skin, and a detector obtaining image data corresponding to an image of an area of skin. The device generates a target reflectance value based on the image data and past image data. The target reflectance value is higher than reflectance of at least half of areas corresponding to the image data and past image data. The device determines a desired level of reflectance modification for a location within the area of skin imaged by comparing image data corresponding to reflectance of the location to the target reflectance value, and directs the applicator to selectively apply the composition to the location based on the desired level of reflectance modification.

Abstract: Sulfate-free cleansing compositions that include a surfactant and a conditioning agent are disclosed. The cleansing compositions are suitably thick and have a desired level of clarity. The cleansing compositions, which are slightly acidic, are mild to the skin and/or eyes.

Abstract: The invention relates to a soft chewable dosage form comprising a first active pharmaceutical ingredient encapsulated in a lipid material that is embedded in the soft chewable dosage form and wherein the soft chewable dosage form comprises at least a second active pharmaceutical ingredient as well as a method of treating a subject suffering from a disease or disorder in the gastro intestinal tract using the soft chewable dosage form.

Abstract: This invention relates to methods and compositions for inhibiting the transmission of enveloped viruses, which entails applying a composition containing a high molecular weight hydrophobically-modified polymer to an infectable or ingestible surface that may contain viruses and wherein said anti-viral composition is substantially free of surfactant having an HLB greater than about 12.

Abstract: A phacoemulsification system includes a phacoemulsification probe and a processor. The phacoemulsification probe includes (a) a needle configured for insertion into a lens capsule of an eye, and to be vibrated to emulsify a lens of the eye, (b) an irrigation channel for flowing irrigation fluid into the lens capsule, (c) an aspiration channel for removing material from the lens capsule, (d) a bypass channel fluidly coupled with the irrigation channel and with the aspiration channel, (e) a processor-controlled valve configured to control a level of fluid communication between the irrigation channel and the aspiration channel via the bypass channel, and (f) one or more sensors configured to measure fluid pressure at a distal portion of one or both of the irrigation channel and the aspiration channel. The processor is configured to adaptively adjust the valve based on the fluid pressure measured by the one or more sensors.

Abstract: Disclosed are hydrophobic, acrylic materials having both high refractive index and a high Abbe number. The materials may have an internal wetting agent, are well suited for use as implantable ophthalmic devices, and have a refractive index which may be edited through application of energy. When used for an intraocular lens, the high refractive index allows for a thin lens which compresses to allow a small incision size.

Abstract: A system of contact lenses includes at least two contact lenses, each lens having a visual correction for a non-rotationally symmetric eye aberration. Each lens has a different level or degree of a stabilization that is characterized by a thickness differential between a thickness of a stabilization zone and a thickness of a non-stabilization zone.

Abstract: A contact lens package includes a base having a proximal end and a distal end, a solution well between the proximal end and the distal end, a contact lens support in the solution well, a top opening between the proximal end and the distal end and over the contact lens support, and a via through a wall of the base adjacent the well, the via providing a fluid exit for solution within well. A removable lid overlying the top opening may be removably affixed over the top opening such that a user may remove the lid to access the contact lens. Using this package, fluid can be drained away from the contact lens in the package before removal from the package by a user, thus providing good adhesion between a user's finger or applicator and the lens over prior packaging.

Abstract: A shaped tampon with a groove pattern and a combination of external shapes varying radially and longitudinally.

Abstract: Described are visible light absorbing compounds. The compounds absorb various visible light wavelengths, such as in the region of 500 to 625 nm, and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices.

Abstract: This intraocular lens (IOL) injector cartridge has a proximal opening in a main body for receiving an IOL. The main body has a lumen that extends longitudinally to a distal end having an opening smaller than the IOL. Passage through the lumen compresses or rolls the IOL so that when the distal end is inserted through a small incision in the eye the IOL can be expelled into the capsular bag. The distal end of the cartridge is beveled with a leading tip in front of a trailing heel. The characteristics of the beveled end are such that damage to the IOL is reduced. The bevel may be straight or curved and includes a distal face defined by the thickness of the distal end between the lumen and an exterior surface. The distal face may be flush with the bevel or chamfered. An inner corner angle between the distal face and the lumen is ?60° to reduce the chance of scratching the IOL as it passes out of the distal opening.

Abstract: Use of an artificial intelligence engine to provide skin care treatment is disclosed.

Abstract: The present invention relates to borate and phosphate containing compositions, especially eye care compositions, achieving physiologically compatible pH and tonicity as well as good bacteriostatic properties. Methods of using the compositions of the present invention are also disclosed.

Abstract: Methods and compositions are provided for treating weight related conditions and metabolic disorders by altering microbiota in a subject. One aspect provides methods and compositions to alter microbiota in a subject by administering to the subject a composition that includes a substantially purified microbiota from phyla such as Bacteroidetes, Proteobacteria, Firmicutes and Verrucomicrobia or orders such as Bacteroidales, Verrucomicrobiales, Clostridiales and Enterobacteriales or genera such as Alistipes, Clostridium, Escherichia, and Akkermansia. Another aspect includes a pharmaceutical composition for altering microbiota that includes a therapeutically effective amount of substantially purified microbiota and a pharmaceutically acceptable carrier. Yet another aspect includes methods for treating a disorder, such as obesity, in a subject in need of such treatment by changing relative abundance of microbiota in a gastrointestinal tract of the subject without or in addition to a surgical procedure.

Abstract: A surgical system for the treatment of ocular problems including a surgical cassette, a surgical console operatively coupled to the surgical cassette and further including a processor, a vacuum source positioned in-line with a vacuum regulator and a mass air flow controller, and a tank fluidly connected to the mass air flow controller, wherein the processor is configured to calculate an air flow set point in accordance with a received at least one user-defined fluid flow rate set point; and wherein the mass air flow controller modulates air flow from the tank to the vacuum source in accordance with the received the air flow set point to meet a user-defined fluid flow rate.

Abstract: A system including first and second camera assemblies, and a processor. The first camera assembly includes a first camera producing, in a first imaging modality, a first image of an organ acquired from a first angle, and a first position sensor, producing a first position signal indicative of a first position and a first orientation, of the first camera. The second camera assembly includes a second camera, producing, in a second imaging modality, a second image of the organ acquired from a second angle, and a second position sensor, producing a second position signal indicative of a second position and a second orientation, of the second camera. The processor registers between the first and second images based on the first and second position signals and displays, based on the first and second images, a third image including a combination of at least part of the first and second images.

Abstract: An automated product locker includes a housing and a drawer configured to be slidably stowable within the housing. The defines a storage area for storing product. Visual indicators on the product locker indicate respective positions, i.e., locations of the product within the storage area, so that desired products may located by the user. Upon withdrawal or closure of a door by a user, a machine vision system, such as a camera, may capture information about the product and inventory the product based, at least in part, on the information identified from images of the product obtaining by the machine vision system.

Abstract: Product selection packaging for a consumer product that improves the consumer's ability to quickly sort through numerous criteria in a complex decision making process and determine whether that particular consumer product is appropriate for his or her purchase and use is disclosed. The product selection packaging, which is designed for a consumer product includes (a) an interface; and (b) at least one product selection indicia associated with the interface, wherein the selection indicia assist the consumer with determining whether or not the product is appropriate for the consumer's purchase or use.