Patents Assigned to Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
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Patent number: 5644012Abstract: A polyester represented by the following general formula (I) and a copolymer which comprises two structural units represented by the following general formulae (I') and (II). ##STR1## and a coating material for use in large intestine-selective drug release pharmaceutical preparations, which contains the above polyester and/or copolymer. The polyester and copolymer of the present invention contain a saccharide residue which is hydrolyzed and/or assimilated specifically in the large intestine, drugs contained in solid oral pharmaceutical administration pharmaceutical preparations coated with the coating material of the present invention are not decomposed or absorbed by digestive organs other than the large intestine, but instead are released selectively and therefore in a high concentration in the large intestine.Type: GrantFiled: November 16, 1992Date of Patent: July 1, 1997Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Koji Iritani, Tetsuya Kawasaki, Nobutaka Tani, Shigeki Masuda, Yoshiaki Yano
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Patent number: 5641852Abstract: Disclosed is a thermosetting resin composition comprising cyanate resin, a compound containing at least one or more than one of a phenolic hydroxyl radical and an epoxy resin, wherein said resin has excellent adhesive and heat resistant properties while at the same time possessing a low hardening contraction rate and contributing to higher dimensional stability, and method of making the same.Type: GrantFiled: January 11, 1996Date of Patent: June 24, 1997Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Hiroyuki Tsuji, Shoji Hara, Hirosaku Nagano
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Patent number: 5639825Abstract: When a thermosetting composition comprising(A) a resin having hydroxyl group,(B) a hydrolyzable silyl group-containing polymer,(C) a hydrolyzable silicon compound and(D) a curing catalyst is used, coating materials having no problem as to bad-smelling can be obtained and the coating films formed therefrom are improved in physical properties such as adhesion, solvent resistance and hardness.Type: GrantFiled: October 4, 1994Date of Patent: June 17, 1997Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Toshiro Nanbu, Hirotoshi Kawaguchi, Hisao Furukawa, Yasushi Kato
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Patent number: 5637382Abstract: The object of the invention is to embody further thinning of a double layer flexible printed circuit board (FPC) and provide a flexible copper-coated laminate capable of producing such a novel flexible printed circuit board distinguished in bending characteristic and heat-resistant property and provide a printed circuit board using the novel flexible copper-coated laminate. To achieve the above object, novel flexible copper-coated laminates 10 and 12 according to the present invention are respectively composed by directly forming a copper layer 16 having a thickness of 10 .mu.m or less than 10 .mu.m on a single surface or both surfaces of polyimide film 14 which is composed of polyimide polymer containing modulus of initial tensile elasticity of 400 kg/mm.sup.2 or more than 400 kg/mm.sup.2, and which has a thickness of 10 .mu.m or less than 10 .mu.m.Type: GrantFiled: January 26, 1996Date of Patent: June 10, 1997Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Kosuke Kataoka, Eiichiro Kuribayashi, Yoshihide Ohnari
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Patent number: 5635486Abstract: The present invention provides an ophthalmic composition comprising a sleep inducing substance or a sleep inhibiting substance, and the sleep inducing substance or the sleep inhibiting substance is derived from an organism. Thus, the invention provides an ophthalmic composition comprising a sleep adjusting substance which normalizes irregularity of the rhythm of sleep and a liquid ophthalmic medicament comprising the composition, the composition and the medicament being safe and obtainable by anyone, and a method for regulating the rhythm of sleep comprising instilling the ophthalmic medicament including the sleep adjusting substance to an individual.Type: GrantFiled: September 7, 1994Date of Patent: June 3, 1997Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Kozo Yamamoto, Takayoshi Hidaka
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Patent number: 5626552Abstract: A method for solidifying industrial waste containing various toxic metals and other substances without fail and stabilizing the waste so as to prevent the toxic metals, particularly lead, from leaching out. The method comprises mixing a waste containing calcium compounds such as hydroxide, oxide and chloride of calcium with a treatment mainly comprising water glass, adding, if necessary, water hereto to adjust the total water content to 25-75 parts by weight per 100 parts by weight of the waste, kneading the resultant mixture, and aging the same for at least 6 hours in a temperature range of 40.degree. to 100.degree. C., preferably by utilizing the waste heat of a waste incinerator.Type: GrantFiled: July 14, 1995Date of Patent: May 6, 1997Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Takuji Nomura, Hidekazu Kuromatsu, Masakazu Uekita
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Patent number: 5623030Abstract: A curable composition providing a cured product having a silicon type interpenetrating polymer network, which comprises (A) a silsesquioxane ladder polymer, (B) a silicon compound having at least two SiH groups per molecule, (C) a silicon compound having at least two vinylsilyl groups per molecule and (D) a neutral platinum catalyst; and a process for producing a molded article comprising heating the curable composition under a controlled temperature for synchronously causing hydrolysis and condensation of the alkoxysilyl group and/or silanol group and hydrosilylation.Type: GrantFiled: November 29, 1995Date of Patent: April 22, 1997Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Manabu Tsumura, Masafumi Hiraishi, Takahisa Iwahara, Toshifumi Hirose
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Patent number: 5620636Abstract: A foam molded product of a synthetic resin having a continuous hardened surface layer formed uniformly on a part or the whole of its surface during its foam-in-place molding and having a desired thickness. A mold and a process which can make such a product without bringing about any substantial change in an ordinary foam-molding operation. A part of foamable resin particles which are fed into the mold for making the product are caused to contact a mold surface heated to or above the melting point of the particles and melt to form a molten resin layer, and the molten resin layer is hardened to form the hardened surface layer.Type: GrantFiled: August 22, 1995Date of Patent: April 15, 1997Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Tamotsu Kawai, Kinzo Masuda, Masao Ando, Fukuzo Imada, Masahiro Chikada
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Patent number: 5621068Abstract: A thermoplastic polyimide film comprising a thermoplastic polyimide polymer, a polyimide laminate, respectively being suited for use as cover-lay adhesive agent and a cover-lay film capable of exerting distinguished thermal resistant property, processability and adhesion property useful for the manufacture of flexible printed circuit boards, and yet, suited for use as the adhesive-agent layers of flexible copper-coated laminates and bilateral adhesive sheets; and a method of manufacturing the polyimide laminate. The thermoplastic polyimide polymer represented by the general formula (1) specified below: ##STR1## wherein Ar.sub.1, Ar.sub.2, Ar.sub.4 and Ar.sub.6, represents divalent organic radical, whereas Ar.sub.3 and Ar.sub.5 represent quadrivalent organic radical, wherein l, m amd n designate positive integer of 0 to 15, wherein the sum of 1 and m is 1 or more than 1, and wherein t designates positive integer of 1 or more than 1.Type: GrantFiled: February 22, 1995Date of Patent: April 15, 1997Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Yoshifumi Okamoto, Hiroyuki Furutani, Kazuhisa Danno, Junya Ida, Hirosaku Nagano
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Patent number: 5609558Abstract: A waste-treating material which comprises cement and at least one reducing metal, effective for stabilizing industrial wastes containing harmful metals like a heavy metal and the like and cyanides. A preferred example of the reducing metal is iron. Additionally the waste-treating material may also contain at least one member selected from a group consisting of a reducing agent, aluminum sulfate, allophane, and bentonite as the auxiliary. The use of this waste-treating material makes it possible to stabilize the hazardous heavy material and the cyanides contained in the industrial wastes, thereby remarkably contributing to a stabilizing treatment of the industrial wastes.Type: GrantFiled: March 23, 1993Date of Patent: March 11, 1997Assignees: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha, En-Tech Research Institute, Inc.Inventors: Taiichiro Sasae, Tomio Nishida, Masakazu Uekita, Takashi Funahashi
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Patent number: 5602204Abstract: A thermosetting composition (A) a hydroxyl group-containing resin, (B) an alkoxysilane group-containing copolymer and (C) a curing catalyst. The film of the composition is excellent in not only adhesion, gel percentage and surface hardness but also solvent resistance, acid resistance, and stain resistance.Type: GrantFiled: May 22, 1991Date of Patent: February 11, 1997Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Toan Harimoto, Toshiro Nanbu, Jo Kawamura, Hisao Furukawa
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Patent number: 5593814Abstract: A device for controlling cell arrangement having a pattern composed of a cell adhesive surface and a cell non-adhesive surface, which has a good selectivity of cell adhesion and which can provide a fine pattern of cells in high resolution by culturing cells in a usual manner.Type: GrantFiled: September 19, 1994Date of Patent: January 14, 1997Assignee: Kanegafuchi kagaku kogyo Kabushiki KaishaInventors: Takehisa Matsuda, Kazuhiko Inoue, Nobutaka Tani
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Patent number: 5576020Abstract: A polyester represented by the following general formula (I) and a copolymer which comprises two structural units represented by the following general formulae (I') and (II). ##STR1## and a coating material for use in large intestine-selective drug release pharmaceutical preparations, which contains the above polyester and/or copolymer. The polyester and copolymer of the present invention contain a saccharide residue which is hydrolyzed and/or assimilated specifically in the large intestine, drugs contained in solid oral pharmaceutical administration pharmaceutical preparations coated with the coating material of the present invention are not decomposed or absorbed by digestive organs other than the large intestine, but instead are released selectively and therefore in a high concentration in the large intestine.Type: GrantFiled: April 14, 1995Date of Patent: November 19, 1996Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Koji Iritani, Tetsuya Kawasaki, Nobutaka Tani, Shigeki Masuda, Yoshiaki Yano
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Patent number: 5572255Abstract: An image reading apparatus and method in which a plurality of photoelectric energy converting elements disposed in a one-dimensional array is divided every m elements into n first blocks B.sub.1, B.sub.2, . . . , B.sub.n, driving voltages are applied sequentially to the units of m photoelectric energy converting elements in the first blocks B.sub.1, B.sub.2, . . . , B.sub.n, and the electrical signals of the photoelectric energy converting elements are read out. The drive side on which the driving voltage is sequentially applied to the above-mentioned divided n first blocks, B.sub.1, B.sub.2, . . . , B.sub.n is further divided every x first blocks into y second blocks C.sub.1, C.sub.2, . . . , C.sub.y, and are provided a first voltage application means which applies a first driving voltage (D1, D2, . . . , Dy) in sequence to the units of x first blocks B.sub.1, B.sub.2, . . . , B.sub.x in the second blocks C.sub.1, C.sub.2, . . . , C.sub.Type: GrantFiled: April 8, 1994Date of Patent: November 5, 1996Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Satoru Murakami, Hiromi Maeda, Yoichi Hosokawa
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Patent number: 5565345Abstract: A process for preparing 5,6-dihydro-4-hydroxy-(S)-6-methyl-thieno[2,3-b]thiopyran-7,7-dioxide having the formula (II): ##STR1## which comprises subjecting 5,6-dihydro-4-oxo-(S)-6-methyl-thieno[2,3-b]thiopyran-7,7-dioxide having the formula (I): ##STR2## to the action of a microorganism to reduce the thienothiopyran derivative having the formula (I), and collecting 5,6-dihydro-4-hydroxy-(S)-6-methyl-thieno-[2,3-b]thiopyran-7,7-dioxide having the formula (II) from the reaction mixture, wherein said microorganism belongs to the genus selected from the group consisting of Ambrosiozyma, Arthroascus, Ashbya, Candida, Cryptococcus, Hansenula, Kluyveromyces, Lipomyces, Lodderomyces, Metschnikowia, Pachysolen, Pichia, Rhodosporidium, Rhodotorula, Saccharomyces, Saccharomycopsis, Schwanniomyces, Sporidiobolus, Spolobolomyces, Stephanoascus, Trigonopsis, Trichosporon and Wingea, according to which, a simple and effective. process for preparing 5,6-dihydro-4-hydroxy-(S)-6-methyl-thieno-[2,3-b]thiopyran-7,7-dioxide.Type: GrantFiled: January 30, 1995Date of Patent: October 15, 1996Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Yoshihiko Yasohara, Yoshiko Tari, Noboru Ueyama, Junzo Hasegawa, Satomi Takahashi
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Patent number: 5565344Abstract: The present invention is directed to a gene which is related to a D-N-carbamoyl-.alpha.-amino acid amidohydrolase which is an enzyme capable of converting D-N-carbamoyl-.alpha.-amino acids into D-.alpha.-amino acids; a recombinant plasmid in which a DNA fragment containing the gene is incorporated into a vector; a microorganism belonging to the genus Escherichia, Pseudomonas, Flavobacterium, Bacillus, Serratia, Corynebacterium, or Brevibacterium, which is transformed by incorporating the recombinant plasmid thereinto; a process for the production of D-N-carbamoyl-.alpha.-amino acid amidohydrolases, comprising the steps of cultivating the transformed microorganism and collecting the desired product therefrom; a D-N-carbamoyl-.alpha.-amino acid amidohydrolase obtained by the method; and a process for the production of D-.alpha.-amino acids with the aid of an action of the enzyme.The D-N-carbamoyl-.alpha.-amino acid amidohydrolase can be fixed on a support for immobilization and used as an immobilized enzyme.Type: GrantFiled: August 7, 1992Date of Patent: October 15, 1996Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Hirokazu Nanba, Yukio Yamada, Masayuki Takano, Yasuhiro Ikenaka, Satomi Takahashi, Kazuyoshi Yajima
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Patent number: 5560908Abstract: A therapeutic agent for and the treatment of NIDDM which comprises a cytotoxic cytokine or an inducer of a cytotoxic cytokine, as the effective ingredient.Type: GrantFiled: January 19, 1994Date of Patent: October 1, 1996Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Jo Satoh, Takayoshi Toyota
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Patent number: 5556943Abstract: A sheep LFA-3 protein and derivertires thereof, and derivertives of a human LFA-3 protein, gene coding for the proteins, and processes for preparing the proteins. Said proteins have high affinity for human T-cells.Type: GrantFiled: October 24, 1994Date of Patent: September 17, 1996Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Kenji Yamashita, Takaaki Ohara, Hideo Niwa, Fumio Osakada, Takeshi Fukuchi, Tadahiro Edamura, Tetsu Kakutani
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Patent number: 5556636Abstract: The present invention is directed to a sticky composition for medical use comprising a tackifier resin and an oxyalkylene polymer having a silicon-containing group which can be crosslinked by forming a siloxane bond, wherein silicon atom thereof is bound with a hydroxyl group or hydrolytic group, and to a transdermal drug delivery preparation incorporating said sticky composition as a drug carrier. The sticky composition of the present invention possesses excellent adhesive properties, very low skin irritancy and good compatibility with the site of plastering and thus perform as a very safe and effective medical adhesive. The transdermal drug delivery preparation of the present invention offers excellent drug release from the sticky composition.Type: GrantFiled: October 6, 1994Date of Patent: September 17, 1996Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Yoshiaki Yano, Kazuyuki Takeo, Takayoshi Hidaka
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Patent number: 5550282Abstract: Dislcosed is a curable composition of a partially trimerized prepolymer of the dicyanate ester of the formula ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and each is alkyl, perfluoroalkyl, aryl or halogen; and A is a bridge selected from the group consisting of a direct bond, methylene optionally mono- or disubstituted by alkyl, perfluoroalkyl and/or aryl, a five or six membered cycloalkylene, sulfonyl, thio, oxy, carbonyl, phenylene, and xylylene optionally substituted by alkyl at on or both methylene carbon atoms is useful in the manufacture of electrical laminates having excellent dielectric properties in the GHz region.Type: GrantFiled: July 13, 1994Date of Patent: August 27, 1996Assignee: Kanegafuchi Kagaku Kogyo Kabushiki KaishaInventors: Hidenari Tsunemi, Toshinobu Nakata