Abstract: Provided are compositions for preventing or treating cancer including Asarum maculatum Nakai extracts, or a fraction thereof. According to an aspect, an Asarum maculatum Nakai extract has an excellent anticancer efficacy against various cancers including diffuse-type gastric cancer, and a cancer treatment agent having an excellent effect may be developed by using the extract as an active ingredient.
Type:
Application
Filed:
October 7, 2022
Publication date:
April 13, 2023
Applicants:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
Inventors:
Hak Cheol KWON, Jaeyoung KWON, Seong-Hwan KIM, Jung Hwan LEE, Jin Wook CHA, Ho Seong HWANG, Won Kyu KIM, Yujin KWON, Suyeon CHO, Taek Joo LEE, Jung Hwa KANG, Wan Hee LEE, Hyunki KIM
Abstract: Provided are compositions for preventing or treating cancer, the compositions including Rubus longisepalus var. tozawai (Nakai) T.B.Lee extracts, or a fraction thereof as an active ingredient. According to an aspect, a Rubus longisepalus var. tozawai (Nakai) T.B.Lee extract has an excellent anticancer efficacy against various cancers including diffuse-type gastric cancer, and thus, a cancer treatment agent having an excellent effect may be developed by using the extract as an active ingredient.
Type:
Application
Filed:
October 7, 2022
Publication date:
April 13, 2023
Applicants:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
Inventors:
Hak Cheol KWON, Jaeyoung KWON, Seong-Hwan KIM, Jin Wook CHA, Soon Kwang LEE, Won Kyu KIM, Yujin KWON, Suyeon CHO, Taek Joo LEE, Jung Hwa KANG, Wan Hee LEE, Hyunki KIM
Abstract: A high resolution fluorescence imaging device includes a light guide plate having a fluid channel which allows a solution containing a fluorescent sample to pass; a light source disposed on a side of the light guide plate to irradiate light inward the light guide plate; an image sensor disposed under the light guide plate; and a thin film interposed between the light guide plate and the image sensor, wherein the thin film has a first surface having a plurality of pillars and a second surface, the pillars separate the light guide plate and the image sensor apart from each other, and the second surface is bonded to the light guide plate. According to an embodiment, since the light guide plate acts in place of a filter element, it is possible to manufacture in ultrasmall size and achieve multiple fluorescence imaging without replacing a filter.
Type:
Application
Filed:
October 7, 2022
Publication date:
April 13, 2023
Applicant:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Abstract: Disclosed are a spinning dope for an aramid and carbon-nanotube composite fiber and a method of manufacturing an aramid and carbon-nanotube composite fiber using the same.
Type:
Application
Filed:
March 22, 2022
Publication date:
April 13, 2023
Applicant:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Dae Yoon KIM, Ki Hyun RYU, Bon Cheol KU, Jun Yeon HWANG, Nam Dong KIM, Dong Ju LEE, Seo Gyun KIM
Abstract: Provided is a toothed drum type oil recovery device, which includes: a recovery drum having a center coupled to a rotary shaft and having a plurality of tooth units formed around an outer circumference thereof, wherein one side of the recovery drum is disposed in the water to which oil is spilled so that the oil is recovered by the tooth unit at one side of the recovery drum according to the rotation; and a separation unit containing an oil separating liquid and disposed at the other side of the recovery drum, wherein when the tooth unit moves onto the oil separating liquid at the other side of the recovery drum according to the rotation of the recovery drum, the oil separating liquid is introduced into a space between the tooth units adjacent to each other by means of a capillary action to separate the oil from the tooth unit.
Type:
Grant
Filed:
July 1, 2021
Date of Patent:
April 11, 2023
Assignee:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Abstract: Provided are an apparatus and method for honeycomb artifacts removal for removing honeycomb artifacts in images received from an optical fiber imaging device through a honeycomb artifact removal model. The honeycomb artifact removal apparatus according to an embodiment includes a control unit configured to create a training dataset, build the honeycomb artifact removal model with the created training data, remove a honeycomb artifact in an input image through the built honeycomb artifact removal model and output a corrected image, wherein the control unit is configured to perform preprocessing of a raw image, acquire a honeycomb artifact image through the optical fiber imaging device, and synthesize the preprocessed raw image with the honeycomb artifact image to generate a honeycomb artifact synthesized image, and the training dataset is created by mapping the honeycomb artifact synthesized image as input data and the preprocessed raw image as output data.
Type:
Application
Filed:
May 11, 2022
Publication date:
April 6, 2023
Applicant:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Abstract: A large capacity natural material composition conversion apparatus using a microwave with a preset pressure function includes a chamber including a sealed reaction space accommodating a material, an radiator configured to heat the material by radiating a microwave into the reaction space, a pressure regulator configured to regulate a pressure of the reaction space by supplying a gas into the reaction space, and a controller configured to control the pressure regulator and the radiator, and preliminarily increase a pressure of the reaction space by controlling the pressure regulator before heating the material.
Type:
Grant
Filed:
April 2, 2021
Date of Patent:
April 4, 2023
Assignee:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Jungyeob Ham, Taejung Kim, Bong Chul Chung, Sungdo Ha, Seok Lee, Young Tae Park, Pilju Choi
Abstract: Embodiments relate to a method for generating a video synopsis including receiving a user query; performing an object based analysis of a source video; and generating a synopsis video in response to a video synopsis generation request from a user, and a system therefor. The video synopsis generated by the embodiments reflects the user's desired interaction.
Type:
Grant
Filed:
August 18, 2020
Date of Patent:
April 4, 2023
Assignee:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Ig Jae Kim, Heeseung Choi, Haksub Kim, Yoonsik Yang, Seungho Chae
Abstract: A probe for measuring the activity of caspase-1 according to the present disclosure can specifically image cells or tissues where inflammatory response is induced because it is cleaved by reacting specifically with the active caspase-1 enzyme in vivo and in vitro and re-emits fluorescence. The probe for measuring the activity of caspase-1 can be used for various purposes, such as for imaging of cells or tissues where inflammatory response is induced, as a drug carrier, for screening of a drug inhibiting inflammatory response, etc. The probe for measuring the activity of caspase-1 is applicable both in vivo and in vitro, and can be used for various applications such as high-throughput screening for new drug development, early diagnosis of diseases, etc.
Type:
Grant
Filed:
September 12, 2019
Date of Patent:
April 4, 2023
Assignees:
Korea Institute of Science and Technology, Seoul National University R&DB Foundation
Inventors:
Ick Chan Kwon, Ju Hee Ryu, Young-Ji Ko, Hye-Sun Kim, Nam-Hyuk Cho, Eun-Jeong Yang, Jae Won Lee
Abstract: A nerve cover for covering a nerve within a living body tissue to protect the nerve includes a base of a flat plate shape, and a pair of covers protruding upward the base to form a hole for receiving a nerve, with one end attached to the base and the other end spaced apart from the one end, wherein when the base is bent in an arch shape when viewed from a side, a spacing between the pair of covers is expanded. In addition, an apparatus for insertion of an electrode structure includes a nerve cover fixing part which fixes the nerve cover with the base being bent, and an electrode structure fixing part in which the electrode structure is mounted, and which linearly moves the mounted electrode structure in an insertion direction to insert the electrode structure into the nerve surrounded by the nerve cover.
Type:
Grant
Filed:
October 24, 2019
Date of Patent:
April 4, 2023
Assignees:
Korea Institute of Science and Technology, Research & Business Foundation Sungkyunkwan University
Inventors:
Sehyuk Yim, Donghyun Hwang, Yong Seok Ihn, Keehoon Kim, Sang Rok Oh, Jinwoo Jeong
Abstract: The present disclosure relates to a sensor module for measuring a displacement occurring in a sensor by a confocal principle, a strain sensor device comprising the same, and a method for measuring a strain in a target using the same. Specifically, the sensor module according to an embodiment of the present disclosure includes a first single-mode optical fiber, a first GRIN optical fiber, a multi-mode optical fiber, a second GRIN optical fiber and a second single-mode optical fiber connected in an axial direction, wherein light inputted through the first single-mode optical fiber is transmitted to the second single-mode optical fiber through the series of optical fibers, and light forming a focal point in the core of the second single-mode optical fiber is detected using a confocal principle.
Type:
Application
Filed:
May 20, 2022
Publication date:
March 30, 2023
Applicant:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Abstract: Disclosed are a flexible transparent electrode structure, a method for preparing the same, and an organic optoelectronic device using the same. The flexible transparent electrode structure includes: a flexible substrate; a thin film laminate of a triple-layer structure formed on both sides of the flexible substrate; and a transparent electrode formed on the thin film laminate of a triple-layer structure provided on one side of the flexible substrate, wherein the thin film laminate of a triple-layer structure includes a SiNx thin film, a SiOxNy thin film and a SiOx thin film formed sequentially on the flexible substrate. The flexible transparent electrode structure has superior light transmittance, water permeation resistance and oxygen permeation resistance, which can improve the electrical properties of an organic optoelectronic device.
Type:
Application
Filed:
September 23, 2022
Publication date:
March 30, 2023
Applicant:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Abstract: The present disclosure is directed to providing impeller type oil transportation device including; a transport unit provided such that a mixed fluid including an oil is fed on one side; and an impeller provided in the transport unit, the impeller including a core connected to a rotation axis, and wings extending radially from the core and having hydrophilic teeth on an outer surface to transport the mixed fluid including the oil to the other side of the transport unit by rotation, wherein the impeller is provided in the transport unit such that parts of the wings are exposed above a surface of the mixed fluid, to separate the oil adhered to the teeth while the mixed fluid is fed into a space between the adjacent teeth by capillary flow when the wings exposed above the surface of the mixed fluid move on to the mixed fluid by the rotation.
Type:
Grant
Filed:
March 17, 2022
Date of Patent:
March 28, 2023
Assignee:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Seong-Jin Kim, Myoung-Woon Moon, Young-jin Lee, Seo-Hyun Cho
Abstract: A biosignal-based avatar control system according to an embodiment of the present disclosure includes an avatar generating unit that generates a user's avatar in a virtual reality environment, a biosignal measuring unit that measures the user's biosignal using a sensor, a command determining unit that determines the user's command based on the measured biosignal, an avatar control unit that controls the avatar to perform the command, an output unit that outputs an image of the avatar in real-time, and a protocol generating unit for generating a protocol that provides predetermined tasks, and determines if the avatar performed the predetermined tasks. According to an embodiment of the present disclosure, it is possible to provide feedback in real-time by understanding the user's intention through analysis of biosignals and controlling the user's avatar in a virtual reality environment, thereby improving the user's brain function and motor function.
Type:
Grant
Filed:
November 27, 2019
Date of Patent:
March 21, 2023
Assignee:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Song Joo Lee, Hyung Min Kim, Laehyun Kim, Keun Tae Kim
Abstract: The present disclosure provides an object recognition apparatus, which includes: an actuator unit configured to contact an object and generate vibrations and transmit them through objects based on the inherent characteristic of the object; and a sensor unit connected to the actuator unit to receive the vibration and generate a voltage signal.
Type:
Grant
Filed:
November 12, 2020
Date of Patent:
March 21, 2023
Assignee:
Korea Institute of Science and Technology
Abstract: According to an embodiment of the present invention, the method includes: (a) preparing a liquid cell containing a palladium precursor solution; (b) applying electron beams to the palladium precursor solution contained in the liquid cell; and (c) generating palladium hydride nanoparticles having the hcp crystal structure in the palladium precursor solution.
Type:
Grant
Filed:
September 29, 2020
Date of Patent:
March 21, 2023
Assignee:
Korea Institute of Science and Technology
Inventors:
Dong Won Chun, Sung Jong Yoo, Jaeyoung Hong, Hee-Young Park, Young-Su Lee, Jin-Yoo Suh, Jee-Hwan Bae, Min Kyung Cho
Abstract: The present invention relates to a method for preparing of a nerve conduit using bio-printing technology and a nerve conduit prepared by the same, and it can easily prepare a nerve conduit by simulating a nerve bundle and nerve tissue, and the like, by three-dimensionally printing bio-ink comprising a neuronal regeneration material on one side of a porous polymer scaffold.
Type:
Grant
Filed:
May 15, 2020
Date of Patent:
March 21, 2023
Assignees:
Korea University Research and Business Foundation, Korea Institute of Science and Technology
Inventors:
Jong Woong Park, Young Mee Jung, Soo Hyun Kim, Justin Jihong Chung
Abstract: The present invention comprises the steps of contacting a boron nitride nanotube and a stabilizer in a solvent, and removing a portion of the solvent to obtain a liquid crystal composition including a liquid crystal in which at least a portion of the stabilizer is adsorbed on the surface of the boron nitride nanotube.
Type:
Application
Filed:
December 16, 2021
Publication date:
March 16, 2023
Applicant:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Se Gyu JANG, Hong Jin LIM, Seok Hoon AHN, Hun Su LEE, Yong Ho JOO, Sang Seok LEE, Hyun Jin CHO
Abstract: A fuel cell catalyst including a conductive carrier and core-shell nanoparticles supported on the carrier. The core includes platinum and a transition metal and the shell includes a secondary metal. An electrochemical specific activity measured at a voltage of 0.05 V to 1.05 V (vs. RHE) in a potential range, at a scan rate of 5 mV/s and a rotation rate of 1,600 rpm in an O2-saturated 0.1 M HClO4 electrolyte solution is 0.3 mA/cm2 to 0.6 mA/cm2, and a mass activity is 0.05 mA/?g to 0.08 mA/?g.
Type:
Application
Filed:
August 25, 2022
Publication date:
March 9, 2023
Applicants:
HYUNDAI MOBIS CO., LTD., KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Eun Young YOU, Yun Sik KANG, Dae Jong YOU, Sung Chul LEE, Sung Jong YOO, Se Hyun LEE, Jue Hyuk JANG, Eung Jun LEE
Abstract: Disclosed is a composition for preventing or treating a degenerative brain disease. The composition includes, as an active ingredient, a MECP2 inhibitor for treating the degenerative brain disease, a polynucleotide encoding the MECP2 inhibitor or a recombinant virus containing the MECP2 inhibitor. The composition is useful for the treatment of a degenerative brain disease (particularly Alzheimer's syndrome) caused by beta-amyloid. In addition, the composition is effective in improving or ameliorating deterioration of cognitive functions and social deficits caused by Alzheimer's syndrome.
Type:
Application
Filed:
May 16, 2022
Publication date:
March 9, 2023
Applicant:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY