Patents Assigned to Korea Institute of Science and Technology
  • Patent number: 10601075
    Abstract: As a polymerization solvent for use in the polymerization of monomers for a hydrocarbon-based electrolyte polymer, a mixed solvent containing a first solvent, such as dimethyl acetamide, N-methylpyrrolidone or dimethyl sulfoxide, and an alcohol as a second solvent is used instead of a dimethyl acetamide/toluene mixture or dimethyl acetamide alone according to the related art. By using the mixed solvent, it is possible to obtain a molecular weight of polymer equal to or higher than the molecular weight of polymer obtained from the method according to the related art, even when the reaction time is reduced. Therefore, the disclosed method and polymerization solvent is very useful for a mass production of a hydrocarbon-based electrolyte polymer.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: March 24, 2020
    Assignees: YOULCHON CHEMICAL CO., LTD., KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyoung-Juhn Kim, Jong Hyub Park, Jin Ho Kim, So Young Lee
  • Publication number: 20200086302
    Abstract: The present disclosure relates to a catalyst for electrochemical ammonia synthesis and a method for producing the same. The catalyst has an ammonia synthesis activity up to several times to several tens of times of the activity of the existing single metal or metal oxide catalysts. Thus, when using the catalyst, it is possible to provide a method for electrochemical ammonia synthesis having an improved ammonia production yield and rate.
    Type: Application
    Filed: December 11, 2018
    Publication date: March 19, 2020
    Applicant: Korea Institute of Science and Technology
    Inventors: Hyun Seo Park, Kahyun Hur, Min-Soek Kim, Jimin Kong, Jong Hyun Jang, Chang Won Yoon, Hyung Chul Ham, Suk Woo Nam, Jonghee Han, Ara Jo
  • Publication number: 20200087705
    Abstract: A probe for measuring the activity of caspase-1 according to the present disclosure can specifically image cells or tissues where inflammatory response is induced because it is cleaved by reacting specifically with the active caspase-1 enzyme in vivo and in vitro and re-emits fluorescence. The probe for measuring the activity of caspase-1 can be used for various purposes, such as for imaging of cells or tissues where inflammatory response is induced, as a drug carrier, for screening of a drug inhibiting inflammatory response, etc. The probe for measuring the activity of caspase-1 is applicable both in vivo and in vitro, and can be used for various applications such as high-throughput screening for new drug development, early diagnosis of diseases, etc.
    Type: Application
    Filed: September 12, 2019
    Publication date: March 19, 2020
    Applicants: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Ick Chan KWON, Ju Hee RYU, Young-Ji KO, Hye-sun KIM, Nam-hyuk CHO, Eun-Jeong YANG, Jae Won LEE
  • Publication number: 20200087807
    Abstract: A method for preparing a tightly sealed 3D lipid structure and a tightly sealed 3D lipid structure prepared thereby is disclosed. The method allows for simpler and more convenient preparation of an artificial biomembrane structure on a substrate using a lipid material, by using a plurality of transparent microwells formed on the substrate, and observation inside the microwells. In addition, a spherical 3D artificial single bilayer structure may be sealed very tightly through a simple method of changing the frequency of an electric field applied vertically to the microwells having a lipid layer formed. Through this, a biomimetic 3D structure having the structural and/or functional characteristics of a cell membrane constituting a cell can be provided more effectively.
    Type: Application
    Filed: March 29, 2019
    Publication date: March 19, 2020
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Tae Song KIM, Dong-Hyun KANG
  • Publication number: 20200088743
    Abstract: According to a method for monitoring post-translational modifications of protein is provided, a first microbead by binding a protein antibody to a base bead is provided. A second microbead by binding a target protein having a first post-translational modification or a second post-translational modification, which are inversely proportional to each other, to the protein antibody of the first microbead, is provided. A third microbead by binding the second microbead to a first post-translational modification antibody is provided. A fourth microbead by binding the second microbead to a second post-translational modification antibody is provided. Impedances of the third and fourth microbeads are measured. A ratio of a first difference, between the impedances of the third microbead and a reference impedance, to a second difference, between the impedances of the fourth microbead and the reference impedance, is obtained.
    Type: Application
    Filed: November 15, 2019
    Publication date: March 19, 2020
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Soo-Hyun LEE, Ji-Yoon KANG, Min-Ho KIM, Yun-Kyung KIM
  • Patent number: 10595013
    Abstract: Provided is a method of forming a dynamic maximal viewing zone (DMVZ) of an autostereoscopic display apparatus. The method includes rearranging viewpoint images for each three dimensional (3D) unit pixels of a certain period k when a viewer deviates in a depth direction from a designed viewing distance (DVD), wherein the certain period k is determined according to a distance by which the viewer deviates in the depth direction from the DVD.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: March 17, 2020
    Assignee: Korea Institute of Science and Technology
    Inventors: Sungkyu Kim, Kihyuk Yoon
  • Patent number: 10593083
    Abstract: Disclosed is a method for facial age simulation based on an age of each facial part and environmental factors, which includes: measuring an age of each facial part on the basis of an input face image; designating a personal environmental factor; transforming an age of each facial part by applying an age transformation model according to the age of each facial part and the environmental factor; reconstructing the image transformed for each facial part; and composing the reconstructed images to generate an age-transformed face. Accordingly, it is possible to transform a face realistically based on an age measured for each facial part and an environmental factor.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: March 17, 2020
    Assignee: Korea Institute of Science and Technology
    Inventors: Ig Jae Kim, Sung Eun Choi, Sang Chul Ahn
  • Publication number: 20200079994
    Abstract: Provided is a dye-sensitized upconversion nanophosphor including a core, a first shell surrounding at least part of the core, and an organic dye bonded to a surface of the nanophosphor to have an absorption band ranging from 650 nm to 850 nm and be excited in a near-infrared region to emit visible light.
    Type: Application
    Filed: March 6, 2019
    Publication date: March 12, 2020
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Ho Seong JANG, Joon Soo HAN, A Ra HONG, So Hye CHO, Seung Yong LEE, Hyung Duk KO
  • Publication number: 20200079487
    Abstract: Disclosed are an unmanned aerial vehicle (UAV) having a buoyancy apparatus and an attitude control method thereof, in which the buoyancy apparatus is coupled to the UAV to reduce the energy consumption of rotors such that the time of staying in the air is extended, enabling a long flight, and in which the buoyancy apparatus absorbs the impact energy and reduces the falling speed to thereby ensure sufficient safety for the UAV.
    Type: Application
    Filed: December 12, 2018
    Publication date: March 12, 2020
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jae Wan SHIM, Heon Phil Ha
  • Patent number: 10585976
    Abstract: Disclosed is a device and method for representing HTML elements having three-dimensional (3D) information on web, the device including a virtual space providing unit configured to provide a 3D virtual space that is displayed on the web, and an HTML element placing unit configured to place an HTML element that is displayed in a 3D layout on the 3D virtual space, based on an HTML document.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: March 10, 2020
    Assignee: Korea Institute of Science and Technology
    Inventors: Daeil Seo, Byounghyun Yoo, Heedong Ko
  • Patent number: 10584032
    Abstract: Provided is a method for preparing boron nitride nanotubes, the method including: injecting a boron-metal catalyst composite into a reaction chamber; injecting a nitrogen precursor into the reaction chamber; producing a decomposition product of the boron-metal catalyst composite in a gas state by irradiating the boron-metal catalyst composite with a carbon dioxide laser or a free electron laser; and forming boron nitride nanotubes by reacting the decomposition product of the boron-metal catalyst composite in the gas state with the nitrogen precursor.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: March 10, 2020
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Myung Jong Kim, Hyun Jin Cho, Seokhoon Ahn, Se Gyu Jang, Soo Min Kim, Dong Ick Son, Jun Hee Kim, Tae Hoon Seo
  • Patent number: 10585022
    Abstract: Provided are an extracellular vesicle collecting apparatus using an electrode and a porous membrane and a method for using the same. The extracellular vesicle collecting apparatus includes i) an upper frame in which a pair of through holes is disposed so that a buffer solution flows therethrough, ii) a buffer tube which is inserted in the through holes and in which the buffer solution flows, iii) a positive electrode disposed on the upper frame, iv) a porous membrane located below the upper frame, v) a spacer which is located below the porous membrane and has a hollow space disposed therein, vi) a plurality of guide tubes through which a blood flows in the hollow space, vii) a lower frame which is coupled to the upper frame to be opposite to the upper frame and receives the porous membrane and the spacer therein, and viii) a negative electrode provided below the lower frame. Extracellular vesicles contained in the blood are collected by the porous membrane.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: March 10, 2020
    Assignee: Korea Institute of Science and Technology
    Inventors: Rhokyun Kwak, Ji Yoon Kang, Jaesung Park, Siwoo Cho
  • Patent number: 10585105
    Abstract: The present invention relates to a method for diagnosing a disease using an analysis of oligomer of an abnormal aggregated protein includes: (1) preparing a body fluid sample including at least one of blood, blood plasma, blood serum, saliva, urine, tear, and mucus; (2) making a dilution of the body fluid sample; (3) using a biosensor to measure and detect an aggregated protein in the diluted body fluid sample; (4) analyzing a signal change of the biosensor caused by the dilution of the aggregated protein to determine a slope according to the dilution from the measurements; and (5) analyzing a proportion of the oligomer from the slope according to the dilution to make a diagnosis. The method uses a biosensor to measure the impedance and the protein concentration of blood and detects the slope according to the numerical value of the monomer and the oligomer to diagnose normal or abnormal protein aggregation or the associated diseases with more accuracy.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: March 10, 2020
    Assignee: Korea Institute of Science and Technology
    Inventors: Ji Yoon Kang, Kyeong Sik Shin, Jae Hoon Ji, Tae Song Kim, Young Soo Kim, Sang Yun Kim
  • Publication number: 20200076328
    Abstract: Disclosed is a composite actuator device, which comprises a composite actuator including a silicone and an iron oxide disposed to be mixed inside the silicone, the composite actuator being configured to be driven by applying a power thereto, wherein the composite actuator includes the iron oxide in an amount of 1 to 20 wt %.
    Type: Application
    Filed: October 25, 2018
    Publication date: March 5, 2020
    Applicant: Korea Institute of Science And Technology
    Inventors: Youngsu CHA, Kahye Song
  • Publication number: 20200071698
    Abstract: The present invention relates to a novel anti-miRNA single-stranded nucleic acid maleimide derivative, which comprises an anti-miRNA single-stranded nucleic acid having a nucleic acid sequence complementary to a nucleic acid sequence of an miRNA. Further, the present invention provides an anti-miRNA single-stranded nucleic acid-serum albumin conjugate in which serum albumin is covalently bonded to the anti-miRNA single-stranded nucleic acid maleimide derivative via the maleimide group.
    Type: Application
    Filed: May 29, 2019
    Publication date: March 5, 2020
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sun Hwa KIM, Ick Chan KWON, Kwangmeyung KIM, Hong Yeol YOON, Gi-Jung KWAK, Juho PARK
  • Publication number: 20200071834
    Abstract: Provided is a method of forming an apatite coating, including brining an apatite-forming precursor solution including Ca2+ ions and PO43? ions into direct contact with at least one region of the substrate, emitting a laser beam onto the region of the substrate in direct contact with the precursor solution through the precursor solution, and forming apatite on the region onto which the laser beam is emitted.
    Type: Application
    Filed: August 29, 2019
    Publication date: March 5, 2020
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hojeong JEON, Seung Hoon UM, Yongwoo CHUNG, Hyunseon SEO, Yu Chan KIM, Myoung-Ryul OK, Hyun Kwang SEOK
  • Patent number: 10578622
    Abstract: Disclosed is a citrate detection sensor including a compound represented by the Chemical Formula 1. The citrate detection sensor is bound specifically with citrate which is under-expressed specifically in cells, such as prostate cancer cells, to express a green fluorescence color. Thus, it is possible to detect citrate with ease by using the citrate detection sensor.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: March 3, 2020
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kang Bong Lee, Yun Sik Nam, Kanagaraj Rajalakshmi, Muthusamy Selvaraj
  • Publication number: 20200061904
    Abstract: According to an embodiment of the present disclosure, there is provided a completely new type of 3-dimensional (3D) printing method for producing an object by focusing ultrasound onto material that changes in state by stimulation to solidify it into a desired shape. The method for 3D printing according to an embodiment includes providing material which changes in state by stimulation, setting a target focal point in the material, focusing ultrasound onto the target focal point using at least one ultrasound transducer, and applying stimulation to the material using the focused ultrasound to induce a change in state of the material. According to the embodiments, it is possible to control the precision of the output by controlling the frequency of the ultrasound transducer or the size of the target focal point on system.
    Type: Application
    Filed: August 22, 2019
    Publication date: February 27, 2020
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyung Min Kim, Ki Joo Pahk, Byung Chul Lee, Inchan Youn
  • Publication number: 20200061137
    Abstract: Provided are a pharmaceutical composition for preventing or treating dry eye syndrome, including an extract of Terminalia chebula or a fraction thereof as an active ingredient, and a method of preventing or treating dry eye syndrome in an individual.
    Type: Application
    Filed: August 23, 2019
    Publication date: February 27, 2020
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jungyeob Ham, Jin-Chul Kim, Chang Geon Kim, Bong Geun Song, Taejung Kim, Pilju Choi, Seon-Jun Choi
  • Publication number: 20200061584
    Abstract: Disclosed is a method for preparing a carbon-supported platinum-transition metal alloy nanoparticle catalyst using a stabilizer. According to the method, the transition metal on the nanoparticle surface and the stabilizer are simultaneously removed by treatment with acetic acid. Therefore, the method enables the preparation of a carbon-supported platinum-transition metal alloy nanoparticle catalyst in a simple and environmentally friendly manner compared to conventional methods. The carbon-supported platinum-transition metal alloy nanoparticle catalyst can be applied as a high-performance, highly durable fuel cell catalyst.
    Type: Application
    Filed: February 6, 2019
    Publication date: February 27, 2020
    Applicants: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, GLOBAL FRONTIER CENTER FOR MULTISCALE ENERGY SYSTEMS
    Inventors: Sung Jong YOO, Sehyun LEE, Hee-Young PARK, Jong Hyun JANG, Jin Young KIM, Hyoung-Juhn KIM, Jea-woo JUNG