Patents Assigned to Laboratoires Jacques Logeais
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Patent number: 5804589Abstract: The present invention relates to the use of the compounds of formula: ##STR1## in which R.sub.1 is a linear, branched or cyclized C.sub.1 -C.sub.5 alkyl radical andR.sub.2 represents a hydrogen atom, a linear or branched C.sub.1 -C.sub.5 alkyl radical, a hydroxyl radical, a C.sub.1 -C.sub.5 alkoxy radicalor a C.sub.1 -C.sub.2 hydroxyalkyl radical, andR.sub.3 represents a hydrogen atomor R.sub.2 and R.sub.3 both represent a C.sub.1 -C.sub.5 alkyl radical,these compounds being 2R in configuration, as well as of the racemates comprising these compounds, and of their pharmaceutically acceptable salts, for the manufacture of a medicament intended for the treatment of pain of visceral origin.Type: GrantFiled: November 7, 1997Date of Patent: September 8, 1998Assignee: Laboratoires Jacques LogeaisInventors: Thierry Bouyssou, Helene Christinaki, Alain Renaud
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Patent number: 4699918Abstract: This invention relates to therapeutically useful compounds, particularly in the cardiovascular field, having the formula: ##STR1##Type: GrantFiled: September 17, 1985Date of Patent: October 13, 1987Assignee: Laboratoires Jacques LogeaisInventors: Jacques G. Maillard, Tri V. Van, Jacky M. Legeai, Marguerite M. Benharkate
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Patent number: 4556674Abstract: This invention relates to therapeutically useful compounds, particularly in the cardiovascular field, having the formula: ##STR1##Type: GrantFiled: January 17, 1984Date of Patent: December 3, 1985Assignee: Laboratoires Jacques LogeaisInventors: Jacques G. Maillard, Tri V. Van, Jacky M. Legeai, Marguerite M. Benharkate
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Patent number: 4443468Abstract: This invention relates to compounds having the general formula: ##STR1## in which ##STR2## is selected from: a radical ##STR3## in which R'.sub.1 is hydrogen and R'.sub.2 is selected from hydrogen; C.sub.1-6 alkyl; C.sub.2-6 alkenyl; C.sub.2-6 alkynyl; phenyl; phenyl C.sub.1-6 alkyl; mono-, di- and trimethoxyphenyl C.sub.1-6 alkyl; C.sub.1-6 alkoxy; benzyloxy; di-C.sub.1-6 alkylamino-C.sub.1-6 alkyl; C.sub.1-6 hydroxyalkyl; C.sub.1-6 alkyloxycarbonyl-C.sub.1-6 alkyl; or R'.sub.1 and R'.sub.2 are joined to form a heterocyclic ring;and their pharmacologically acceptable inorganic and organic acid addition salts.Said compounds are therapeutically useful for the treatment of dysrhythmia.Type: GrantFiled: March 5, 1982Date of Patent: April 17, 1984Assignee: Laboratoires Jacques LogeaisInventors: J. Georges Maillard, Jacky Legeai
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Patent number: 4423056Abstract: This invention relates to compounds of the formula (I): ##STR1## in which: R is selected from hydrogen and C.sub.1-6 alkyl and R' is selected from hydrogen and C.sub.1-6 alkyl; and their pharmaceutically acceptable acid addition salts.Said compounds are therapeutically useful for the treatment of circulatory insufficiencies.Type: GrantFiled: March 10, 1982Date of Patent: December 27, 1983Assignee: Laboratoires Jacques LogeaisInventors: Jacques G. Maillard, Pierre Delaunay, Jacky M. G. Legeoi
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Patent number: 4339384Abstract: This invention relates to compounds having the general formula: ##STR1## in which ##STR2## is selected from: a radical ##STR3## in which R'.sub.1 is hydrogen and R'.sub.2 is selected from hydrogen; C.sub.1-6 alkyl; C.sub.2-6 alkenyl; C.sub.2-6 alkynyl; phenyl; phenyl C.sub.1-6 alkyl; mono-, di- and trimethoxyphenyl C.sub.1-6 alkyl; C.sub.1-6 alkoxy; benzyloxy; di-C.sub.1-6 alkylamino-C.sub.1-6 alkyl; C.sub.1-6 hydroxyalkyl; C.sub.1-6 alkyloxycarbonyl-C.sub.1-6 alkyl;a radical ##STR4## in which R".sub.1 and R".sub.2 are C.sub.1-6 alkyl; a radical ##STR5## in which n is selected from 4, 5 and 6; the radical ##STR6## and the radical ##STR7## and their pharmacologically acceptable inorganic and organic acid addition salts.Said compounds are therapeutically useful for the treatment of dysrhythmia.Type: GrantFiled: July 3, 1979Date of Patent: July 13, 1982Assignee: Laboratoires Jacques LogeaisInventors: Jacques G. Maillard, Jacky Legeai
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Patent number: 4337343Abstract: This invention relates to compounds of the formula (I): ##STR1## in which: R is selected from hydrogen and C.sub.1-6 alkyl and R' is selected from hydrogen and C.sub.1-6 alkyl; and their pharmaceutically acceptable acid addition salts.Said compounds are therapeutically useful for the treatment of circulatory insufficiencies.Type: GrantFiled: June 18, 1980Date of Patent: June 29, 1982Assignee: Laboratoires Jacques LogeaisInventors: Jacques G. Maillard, Pierre P. A. Delaunay, Jacky M. G. Legeai
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Patent number: 4325954Abstract: The present invention relates to compounds having the formula: ##STR1## in which: n is equal to 1 or 2,R.sub.1 represents a hydrogen atom and R.sub.2 represents a phenyl group or a benzofuryl group; or R.sub.2 represents a hydrogen atom and R.sub.1 represents a phenyl group or a benzyl group; andgrouping -A-B- represents a group of the formula: ##STR2## or --CO--(CH.sub.2).sub.3 --in which R represents a hydrogen atom, a C.sub.1-6 alkyl radical, a phenyl group, a benzyl group, a methylthioethyl group, or a group having the formula --(CH.sub.2).sub.m --COOR' in which m is equal to 0, 1 or 2 and R' is a C.sub.1-6 alkyl radical,and their pharmacologically acceptable acid addition salts.These compounds are useful in the treatment of depressions.Type: GrantFiled: February 1, 1980Date of Patent: April 20, 1982Assignee: Laboratoires Jacques LogeaisInventors: Jacques G. Maillard, Tri Vovan, Jacky M. Legeai
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New benzo [d] thiazole derivatives, process for their preparation and their therapeutic applications
Patent number: 4208420Abstract: This invention relates to compounds having the general formula: ##STR1## and their pharmaceutically acceptable acid addition salts having the formula: ##STR2## in which: R represents hydrogen or a C.sub.1-4 alkyl radical,R' represents hydrogen or a C.sub.1-4 alkyl radical,m is 0, 1, 2 or 3,n is 3, 2, 1 or 0,the sum m+n being always equal to 3, andX.sup.- represents an anion formed by a pharmaceutically acceptable acid.Said compounds are typically useful as analgesic agents and as stimulants of the sympathetic nervous system, and also as central and peripheral vasoregulator agents.Type: GrantFiled: October 11, 1978Date of Patent: June 17, 1980Assignee: Laboratoires Jacques LogeaisInventors: Jacques Maillard, Pierre Delaunay, Jacky Legeai -
Patent number: 4181736Abstract: This invention relates to phenylacetic acid derivatives having the formula: ##STR1## in which A represents a grouping ##STR2## R, R.sub.2, R.sub.3 and R.sub.4, which may be the same or different, represent each hydrogen or an alkyl group, and represents a single or double carbon-carbon bond; and their salts with inorganic and organic bases. Said compounds possess anti-inflammatory and analgesic activities that make them therapeutically useful, in particular for the treatment of rheumatic diseases and of local inflammations.Type: GrantFiled: November 21, 1978Date of Patent: January 1, 1980Assignee: Laboratoires Jacques LogeaisInventor: Jacques G. Maillard
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Patent number: 4031133Abstract: This invention relates to phenylacetic acid derivatives having the formula: ##STR1## in which A represents a grouping ##STR2## R, R.sub.2, R.sub.3 and R.sub.4, which may be the same or different, represent each hydrogen or an alkyl group, and represents a single or double carbon-carbon bond; and their salts with inorganic and organic bases. Said compounds possess anti-inflammatory and analgesic activities that make them therapeutically useful, in particular for the treatment of rheumatic diseases and of local inflammations.Type: GrantFiled: August 31, 1972Date of Patent: June 21, 1977Assignee: Laboratoires Jacques LogeaisInventor: Jacques Georges Maillard
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Patent number: 3935255Abstract: This invention relates to compounds having the formula: ##SPC1##In which R is hydrogen or alkyl containing 1-4 carbon atoms and A and B both represent a hydrogen atom ot form together a carbon-carbon bond, and their salts with inorganic or organic bases.Said compounds have analgesic and anti-inflammatory properties.Type: GrantFiled: August 28, 1974Date of Patent: January 27, 1976Assignee: Laboratoires Jacques LogeaisInventor: Jacques Georges Maillard