Patents Assigned to LABORATORY FOR SYNTHETIC CHEMISTRY AND CHEMICAL BIOLOGY LIMITED
  • Methods of iron catalyzed C-H bond amination
    Patent number: 12098126
    Abstract: Described herein is an iron(II)-phthalocyanine catalyzed C—H bond amination of alkyl azides. The catalyst is effective to produce intramolecular amination of saturated C—H bonds in moderate to excellent yields and the methods are tolerant of a wide scope of substrates. The methods described are useful for the synthesis of natural products derivatives and for the late-stage functionalization of pharmaceuticals.
    Type: Grant
    Filed: August 22, 2022
    Date of Patent: September 24, 2024
    Assignees: VERSITECH LIMITED, LABORATORY FOR SYNTHETIC CHEMISTRY AND CHEMICAL BIOLOGY LIMITED
    Inventors: Chi-Ming Che, Tingjie You