Abstract: The present invention is provides isolated riboswitches with FRET pairs for distinguishing changes in regulatory interactions controlled by the expression platform domain found in riboswitches. The invention further provides methods of using those riboswitches to detect structural changes in the expression platform domain and to identify potential antibiotics.

Abstract: The present invention relates to a monolithic organic copolymer prepared by copolymerization of at least one monomer of the group consisting of styrene, (C1-C3)alkylstyrene, (meth)acrylic acid and esters thereof with a crosslinker in the presence of a macroporogen and a microporogen, wherein a) the sum of said at least one monomer of the group and the crosslinker is 10-20%, preferably 10-15%, by volume of the reaction mixture, with the rest being essentially macroporogen and microporogen, and the degree of said copolymerization is at least 70%, preferably at least 90%, more preferably at least 99%, or b) the sum of said at least one monomer of the group and the crosslinker is 30-50%, preferably 35-45%, by volume of the reaction mixture, with the rest being essentially macroporogen and microporogen, and the degree of said copolymerization is in the range of 25-60%, preferably 35-50%.

Abstract: The present invention is provides isolated riboswitches with FRET pairs for distinguishing changes in regulatory interactions controlled by the expression platform domain found in riboswitches. The invention further provides methods of using those riboswitches to detect structural changes in the expression platform domain and to identify potential antibiotics.

Abstract: The invention relates to a compound of formula (I), or a pharmacologically or cosmetically acceptable salt or derivative thereof, wherein R1 to R5 are selected from the groups R1 representing -alkyl, -vinyl, —CHOH—CH2OH, R2 representing H, —OH, —Oalkyl, —Oacyl, saccharide groups, modified saccharide groups (e.g. malonylated), R3 representing —H, —OH, —Oalkyl, —Oacyl, modified —Oacyl (e.g. malonylated), saccharide groups, modified saccharide groups (e.g. malonylated), R4, R5 representing —COOH, -carbonic esters, for use as drug, antioxidant, food supplement. The invention also relates to a method for producing the compound of formula (I).

Abstract: Particles and monoliths are used for providing an ionized analyte for mass analysis by photon desorption having a size in the range of 0.5-100 ?m, wherein the particles or monoliths are modified with a chemical compound capable of absorbing photons having a wave-length of at least 300 nm. The particles and monoliths allow the use of MALDI-MS for the high throughput screening of molecules having a molecular weight lower than 700 ? without interfering signals or with only a limited number of background signals.

Abstract: Monolithic organic copolymer prepared by copolymerisation of a phenyl (meth)acrylate and a phenylene di(meth)acrylate in the presence of a porogen, wherein said copolymerisation is carried out at a temperature of at least 70° C. This polymer can be used as chromatographic material for separating biopolymers and small molecules.

Abstract: The present invention relates to a monolithic organic copolymer prepared by copolymerization of at least one monomer of the group consisting of styrene, (C1-C3)alkylstyrene, (meth)acrylic acid and esters thereof with a crosslinker in the presence of a macroporogen and a microporogen, wherein a) the sum of said at least one monomer of the group and the crosslinker is 10-20%, preferably 10-15%, by volume of the reaction mixture, with the rest being essentially macroporogen and microporogen, and the degree of said copolymerization is at least 70%, preferably at least 90%, more preferably at least 99%, or b) the sum of said at least one monomer of the group and the crosslinker is 30-50%, preferably 35-45%, by volume of the reaction mixture, with the rest being essentially macroporogen and microporogen, and the degree of said copolymerization is in the range of 25-60%, preferably 35-50%.

Abstract: The invention relates to particles and monoliths for providing an ionized analyte for mass analysis by photon desorption having a size in the range of 0.5-100 ?m, wherein said particles or monoliths are modified with a chemical compound capable of absorbing photons having a wave-length of at least 300 nm. Said particles and monoliths allow the use of MALDI-MS for the high throughput screening of molecules having a molecular weight lower than 700? without interfering signals or with only a limited number of background signals.

Abstract: Monolithic organic copolymer prepared by copolymerisation of an alkylstyrene and a divinylbenzene or a derivative thereof in the presence of a porogen, wherein said porogen comprises decanol and at least one of the group consisting of tetrahydrofuran and toluene.

Abstract: Monolithic organic copolymer prepared by copolymerisation of an alkylstyrene and a divinylbenzene or a derivative thereof in the presence of a porogen, wherein said porogen comprises decanol and at least one of the group consisting of tetrahydrofuran and toluene.