Abstract: An object of the present invention is to provide a toothbrush that enables an appropriate brushing pressure to be more reliably recognized. A head portion (10) provided on a tip end side in a long axis direction and having a bristle tufting surface (11), a grip portion (30) disposed on a rear end side from the head portion, and a neck portion (20) disposed between the bristle tufting surface and the grip portion are provided. A sound generation portion (70) that generates a click sound due to deformation when an external force in a first direction orthogonal to the bristle tufting surface exceeds a threshold value is provided on a rear end side from the bristle tufting surface.

Abstract: A toothbrush includes an anisotropic deformation portion (70) on a rear end side from the bristle tufting surface (11), and a bending strength in a first direction orthogonal to the bristle tufting surface that is smaller than a bending strength in a second direction orthogonal to the long axis direction and the first direction. The anisotropic deformation portion includes an elastic deformation portion (90) that connects a first region on the tip end side from the anisotropic deformation portion and a second region on the rear end side from the anisotropic deformation portion. The elastic deformation portion is elastically deformable in the first direction and the second direction, and bending load when the head portion is displaced in the first direction is lower than a bending load when the head portion is displaced in the second direction.

Abstract: A toothbrush includes a head portion (10) having a bristle tufting surface; a grip portion (30) disposed on a rear end side from the head portion; a neck portion (20) disposed between the bristle tufting surface (11) and the grip portion; and a sensing portion (70) for sensing that an external force in a first direction orthogonal to the bristle tufting surface exceeds a threshold value. A reversal portion (80) connects a first region and a second region, and snaps, buckles, and reverses as the head portion is displaced on a rear surface side due to the external force exceeding the threshold value. An elastic deformation portion (90) connects the first region and the second region, and elastically deforms at least up to the external force at which the reversal portion snaps, buckles, and reverses.

Abstract: A toothbrush enables an appropriate brushing pressure and includes a sensing portion for sensing that an external force in a first direction orthogonal to the bristle tufting surface exceeds a predetermined value on a rear end side from the bristle tufting surface. The sensing portion changes a relationship between a displacement amount of the head portion when a load is applied to the head portion and a repulsive force generated according to the displacement amount from an increase to a decrease in the repulsive force at a first threshold value. The first threshold value relates to an increase in the displacement amount, and stops the decrease in the repulsive force at a second threshold value. The second threshold value relates to when the displacement amount is larger than the first threshold value.

Abstract: A toothbrush capable of inhibiting damage of an oral cavity of a user that includes: a head section that has a bristle implanting surface on a front end side; a handle section that is disposed on a rear end side from the head section and has a handle section main body; and a neck section that is disposed between the bristle implanting surface and the handle section. The toothbrush has a deforming portion that is located on the rear end side from the bristle implanting surface and is deformed, while stress characteristics associated with bending due to an external force acting on the head section are in a plane stress condition.

Abstract: A method for producing a fatty acid polyoxyethylene methyl ether in which ethylene oxide is added to a fatty acid methyl ester component comprising, as a main component, a fatty acid methyl ester having a fatty acid residue of 18 to 22 carbon atoms, the addition being conducted in the presence of a composite metal oxide catalyst and at least one alcohol selected from the group consisting of diethylene glycol, ethylene glycol, propylene glycol, ethanol, methanol and isopropyl alcohol.

Abstract: Provided is a testing method for determining an oral indicator by which an oral indicator can be determined. The testing method for determining an oral indicator includes an image acquisition step of acquiring an ultrasonic image of an inside of an attached gingiva of a subject, using a measurement probe, an average brightness acquisition step of acquiring average brightness of the ultrasonic image, and an indicator determination step of determining an oral indicator of the subject by referring to the average brightness and a reference of an oral indicator.

Abstract: A liquid detergent of the present invention contains: component (a): a nonionic surfactant which contains compounds represented by the following formula (1) wherein an average value of m in formula (1) ranges from 5 to 20; and in which a ratio of the compound wherein R1 is a double bond-containing unsaturated hydrocarbon group is equal to or greater than 45% by mass with respect to a total amount of the component (a), and a ratio of the compound wherein R1 is an unsaturated hydrocarbon group having two or more double bonds is equal to or greater than 4% by mass with respect to a total amount of the compounds of formula (1) wherein R1 is an unsaturated hydrocarbon group; and component (b): an anionic surfactant. R1CO(EO)mOR2??(1) wherein R1 is a saturated or unsaturated hydrocarbon group having 15 to 17 carbon atoms; EO is an oxyethylene group; m is a positive integer; and R2 is an alkyl group having 1 to 3 carbon atoms.

Abstract: A coated ?-sulfofatty acid alkyl ester salt particle group containing ?-sulfofatty acid alkyl ester salt particles (A) and a zeolite particle group-containing coating component (B) with which the particles (A) are coated, in which the zeolite particle group is a zeolite particle group (b1) having a mean particle size of equal to or greater than 0.8 ?m and less than 3.8 ?m.

Abstract: Disclosed is an ethoxylation catalyst having a BET specific surface area of 40 to 150 m2/g and including calcium sulfate particles including at least one kind of compound selected from the group consisting of calcium sulfate 0.5 hydrate and type III anhydrous calcium sulfate.

Abstract: It is an object of the present invention to provide a marker substance capable of accurately determining a risk of developing metabolic syndrome in vivo. That is, the present invention provides the followings: a marker peptide for determining the risk of developing the metabolic syndrome; an antibody or an aptamer bound to the marker peptide for determining the risk of developing the metabolic syndrome; a microarray in which the antibody or the aptamer bound to the marker peptide for determining the risk of developing the metabolic syndrome has been immobilized on a carrier; a method for determining the risk of developing the metabolic syndrome, comprising measuring an amount or the presence or absence of the marker peptide for determining the risk of developing the metabolic syndrome in a biological sample collected from a subject; and a kit for determining the risk of developing the metabolic syndrome, comprising the antibody or the aptamer or comprising the microarray.

Abstract: A detergent composition containing an ?-sulfo fatty acid alkyl ester salt and a fragrance composition, wherein the amount of the ?-sulfo fatty acid alkyl ester salt is from 1 to 30% by mass relative to the total mass of the detergent composition, the fragrance composition contains a fragrance (A) described below, and the amount of the fragrance (A) is from 0.07 to 0.5% by mass relative to the total mass of the detergent composition. Fragrance (A): a fragrance composed of at least one fragrance component selected from the group consisting of dihydromyrcenol, isobornyl acetate, ?-hexyl cinnamic aldehyde, lilial, tetrahydrolinalool, amyl salicylate, verdox, vertenex, tricyclodecenyl acetate, tricyclodecenyl propionate, Iso E Super and habanolide.

Abstract: The object of the present invention is to provide a marker substance capable of determining a risk of hyperglycemia in vivo with high accuracy. The present invention provides the following: a marker peptide for determining the risk of hyperglycemia; an antibody or an aptamer bound to the marker peptide for determining the risk of hyperglycemia; a microarray wherein the antibody or the aptamer to be bound to the marker peptide for determining the risk of hyperglycemia has been immobilized onto a carrier; a method of determining the risk of hyperglycemia wherein an amount or the presence/absence of the marker peptide for determining the risk of hyperglycemia is measured in a biological sample collected from a subject; and a kit for determining the risk of hyperglycemia comprising the antibody or the aptamer, or the microarray.

Abstract: This liquid detergent contains an ?-sulfofatty acid ester salt (component (a)), an alkylbenzene sulfonate (component (b)), a polyoxyethylene alkyl ether sulfate (component (c)), and an alkanolamine (component (d)). The amount of the component (a) is 5% by mass or greater; the total amount of the component (b) and the component (c) is 5% by mass or greater; the total amount of the component (a), the component (b), and the component (c) is 10% by mass to 50% by mass, the mass ratio represented by (d)/(a) is 1/5 or greater, and the mass ratio represented by (a)/((b)+(c)) is 1 or less.

Abstract: A surfactant solution of the present invention includes a component (a): an ?-sulfonated fatty acid ester salt; a component (b): an alkanolamine; a component (c): an aromatic sulfonic acid; and a component (d): water, wherein the content of the component (a) is within a range from 30 to 45 mass %, the molar ratio represented by (b)/(a) is within a range from 0.05 to 0.5, and the molar ratio represented by (b)/(c) is within a range from 0.5 to 2.

Abstract: The invention provides a fatty acid alkyl ester sulfonate metal salt mixture of (a) a fatty acid alkyl ester sulfonate metal salt having an endothermic peak area at 50 to 130° C. of less than 50% relative to the whole endothermic peak area at 0 to 130° C. as measured on a differential scanning calorimeter, and (b) a fatty acid alkyl ester sulfonate metal salt having an endothermic peak area at 50 to 130° C. of 50% or more relative to the whole endothermic peak area at 0 to 130° C. as measured on a differential scanning calorimeter, with a ratio of (a) to (b) by mass of 95/5 or less. The mixture of the invention is excellent in anti-caking properties.

Abstract: A panaxadiol-containing composition, containing: panaxadiol; and at least one of sucrose fatty acid ester and lecithin.

Abstract: An object of the present invention is to provide an internal composition capable of exerting various physiological functions such as a brain-function improving function. That is, the present invention provides an internal composition including docosahexaenoic acid and capsanthin, or docosahexaenoic acid, capsanthin, lutein, and zeaxanthin as active ingredients.

Abstract: An object of the present invention is to provide an internal composition capable of exerting various physiological functions such as a brain-function improving function. That is, the present invention provides an internal composition including docosahexaenoic acid and capsanthin, or docosahexaenoic acid, capsanthin, lutein, and zeaxanthin as active ingredients.

Abstract: An object of the present invention is to provide an internal composition capable of exerting various physiological functions such as a brain-function improving function. That is, the present invention provides an internal composition including docosahexaenoic acid and capsanthin, or docosahexaenoic acid, capsanthin, lutein, and zeaxanthin as active ingredients.