Patents Assigned to Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
  • Publication number: 20230298649
    Abstract: A magnetic memory device includes a conductive line that extends in a first direction, and a magnetic track line that extends in the first direction on a top surface of the conductive line. The conductive line may include a first region having a first width in a second direction, and a second region having a second width in the second direction. The first direction and the second direction are parallel to the top surface of the conductive line and are perpendicular to each other. The second width may be greater than the first width. The magnetic track line includes first domains arranged in the first direction on the first region of the conductive line, and second domains arranged in the first direction on the second region of the conductive line. A size of each of the second domains may be less than a size of each of the first domains.
    Type: Application
    Filed: January 12, 2023
    Publication date: September 21, 2023
    Applicants: Samsung Electronics Co., Ltd., Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Stuart Papworth Parkin, Jaechun Jeon, Andrea Migliorini, Ung Hwan Pi
  • Publication number: 20230284610
    Abstract: The invention relates to a method for vitrifying a biological sample. The method includes positioning a sample holder with the biological sample by a transfer device in a starting position. The sample holder has a base and a pin projecting from the base along a holder axis. Further, the biological sample is attached to the pin distant from the base. The method further comprises adding a liquid to the biological sample in the starting position by a liquid dispenser. Further, the method comprises moving the sample holder with the biological sample by the transfer device along a predetermined transfer path from the starting position to a release position, wherein the biological sample in the release position is arranged in or adjacent to a liquefied gas. It is provided that the transfer path is inclined with respect to the holder axis or runs along a circular arc. Furthermore, the invention relates to a vitrification apparatus which is configured to perform the method.
    Type: Application
    Filed: March 9, 2023
    Publication date: September 14, 2023
    Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V.
    Inventors: Friedjof TELLKAMP, Eike-Christian SCHULZ, Hendrik SCHIKORA, Pedram MEHRABI, Martin KOLLEWE
  • Publication number: 20230287087
    Abstract: The present invention pertains in the fields of antibody technology, protein engineering, medicine, pharmacology, infection biology, virology, and medical diagnostics. More specifically, the present disclosure provides VHH antibodies that prevent cell entry of and infection by SARS-CoV-2, a strategy for an enhanced block of the homotrimeric viral spike proteins by symmetry-matching VHH-fusions, implementations of this strategy, as well as VHH antibodies for sensitive detection of SARS-CoV2-infections.
    Type: Application
    Filed: July 29, 2021
    Publication date: September 14, 2023
    Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Dirk GÖRLICH, Volker CORDES, Thomas GÜTTLER, Philip GUNKEL, Renate REES, Jens KRULL, Kathrin GREGOR, Waltraud TAXER, Leonie NEUMANN, Tino PLEINER, Bianka MUSSIL, Ulrike TEICHMANN, Aksu METIN, Oleh RYMARENKO, Jürgen SCHÜNEMANN, Matthias DOBBELSTEIN, Kim Maren STEGMANN, Antje DICKMANNS
  • Publication number: 20230274772
    Abstract: A magnetic memory device may include a magnetic track, which is extended in a first direction, and a first electrode, which is provided at a biasing point of the magnetic track and is configured to apply a voltage to the magnetic track. The magnetic track includes a first region between a first end of the magnetic track and the biasing point and a second region between the biasing point and a second end of the magnetic track. The first electrode may be configured to cause a difference between a current density in the first region and a current density in the second region.
    Type: Application
    Filed: January 12, 2023
    Publication date: August 31, 2023
    Applicants: Samsung Electronics Co., Ltd., Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Stuart Papworth Parkin, Jaechun Jeon, Andrea Migliorini, Ung Hwan Pi
  • Publication number: 20230268706
    Abstract: A broadband light source device for creating broadband light pulses includes a hollow-core fiber and a pump laser source device. The hollow-core fiber is configured to create the broadband light pulses by an optical non-linear broadening of pump laser pulses. The hollow-core fiber includes a filling gas, an axial hollow light guiding fiber core configured to support core modes of a guided light field, and an inner fiber structure surrounding the fiber core and configured to support transverse wall modes of the guided light field. The pump laser source device is configured to create and provide the pump laser pulses at an input side of the hollow-core fiber. The transverse wall modes include a fundamental transverse wall mode and second and higher order transverse wall modes.
    Type: Application
    Filed: April 12, 2023
    Publication date: August 24, 2023
    Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Patrick Sebastian UEBEL, Philip St. J. RUSSELL, Sebastian Thomas BAUERSCHMIDT
  • Publication number: 20230227520
    Abstract: The present invention relates to a protein having G-CSF-like activity comprising a) one or two polypeptide chains; b) a bundle of four ?-helices; and c) two or three amino acid linkers that connect contiguous bundle-forming ?-helices that are located on the same polypeptide chain, wherein each amino acid linker has a length between 2 and 20 amino acids. The invention also provides for a polynucleotide and a vector encoding the protein of the invention, host cells comprising said polynucleotide, a method for producing the protein of the invention and a pharmaceutical composition comprising the protein of the invention. The invention further relates to uses of the proteins of the invention as a research reagent and the use of the protein and/or pharmaceutical composition comprising the same as a medicament, e.g., for use in increasing stem cell production, for use in inducing hematopoiesis and/or for use in mobilizing hematopoietic stem cells.
    Type: Application
    Filed: December 17, 2020
    Publication date: July 20, 2023
    Applicants: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., Eberhard Karls Universität Tübingen
    Inventors: Mohammad ELGAMACY, Birte HERNANDEZ ALVAREZ, Yulia SKOKOWA
  • Publication number: 20230215681
    Abstract: The invention relates to a device (100) for reducing ice contamination of a sample (S) in a chamber (210) of a focused ion beam milling apparatus (200), wherein the device (100) comprises a body (110) configured to be cooled to cryogenic temperatures, wherein the body (110) comprises an aperture (111), which is configured such that an ion beam (I) generated by an ion source (220) can pass from the ion source (220) through the aperture (111) to the sample (S), wherein the body (110) comprises a recess (112), wherein said aperture (111) is arranged in the recess (112). The invention further relates to a focused ion beam milling apparatus (200) and a method for focused ion beam milling of a sample (S).
    Type: Application
    Filed: May 28, 2021
    Publication date: July 6, 2023
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E. V.
    Inventors: Sebastian TACKE, Stefan RAUNSER
  • Patent number: 11688992
    Abstract: A broadband light source device for creating broadband light pulses includes a hollow-core fiber and a pump laser source device. The hollow-core fiber is configured to create the broadband light pulses by an optical non-linear broadening of pump laser pulses. The hollow-core fiber includes a filling gas, an axial hollow light guiding fiber core configured to support core modes of a guided light field, and an inner fiber structure surrounding the fiber core and configured to support transverse wall modes of the guided light field. The pump laser source device is configured to create and provide the pump laser pulses at an input side of the hollow-core fiber. The transverse wall modes include a fundamental transverse wall mode and second and higher order transverse wall modes.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: June 27, 2023
    Assignee: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Patrick Sebastian Uebel, Philip St. J. Russell, Sebastian Thomas Bauerschmidt
  • Patent number: 11682763
    Abstract: The present invention relates to an electrode material comprising at least one sulfur-limonene sulfide component or a composite of the sulfur-limonene sulfide component with a first conductive component; electrodes, in particular cathodes, containing the electrode material; half-cells, cells, and batteries containing the electrodes; and processes for obtaining the electrode material, the electrode, the half-cell, the cell, and the battery comprising electrode material and/or electrodes of the present invention.
    Type: Grant
    Filed: February 6, 2019
    Date of Patent: June 20, 2023
    Assignee: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E. V.
    Inventors: Feixiang Wu, Yan Yu, Joachim Maier
  • Publication number: 20230168255
    Abstract: The present invention relates to a method of determining the capacity of a Cluster 1 mammalian Transcription Factor (TF) for phase separation and/or the capacity for forming a transcriptional condensate in a sample, including a method of determining the presence, localization and/or morphology of a transcriptional condensate comprising said Transcription Factor, and/or of determining the composition of a transcriptional condensate comprising at least one Cluster 1 mammalian TF and/or of determining the transcriptional activity of the TF or a condensate comprising the TF. Further, the present invention relates to an active agent for use in a method of preventing and/or treating a disorder associated with, caused by and/or accompanied with a dysfunction of a biomolecular condensate comprising at least one Cluster 1 mammalian TF.
    Type: Application
    Filed: April 28, 2021
    Publication date: June 1, 2023
    Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Denes HNISZ, Shaon BASU, Sebastian MACKOWIAK
  • Publication number: 20230133208
    Abstract: A computer-implemented method for compressing digital data includes obtaining a sequence of digital data values; mapping the sequence of digital data values to a sequence of code words having non-uniform bit lengths; packing the sequence of code words into a sequence of storage words having uniform bit length and corresponding to a fixed-size piece of data handled as a unit by the instruction set or the hardware of a processor; and outputting the sequence of storage words together with a first bitmask indicating the bit length of each code word, wherein in the method is implemented using special purpose vector instructions.
    Type: Application
    Filed: April 14, 2020
    Publication date: May 4, 2023
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
    Inventor: Ramin MARX
  • Patent number: 11640028
    Abstract: A hollow-core photonic crystal fiber (HC-PCF) (10) for guiding at least one mode of a light field (1) along a mode guiding section (11) of the HC-PCF (10), comprises an outer jacket (12), an inner cladding (13) and a hollow core (14), which extend along the HC-PCF (10), wherein the inner cladding (13) is arranged on an interior surface of the outer jacket (12) and comprises anti-resonant structures (15) surrounding the hollow core (14), and the hollow core (14) has a mode guiding core diameter (d) provided along the mode guiding section of the HC-PCF (10), and wherein at least one fiber end (16) of the HC-PCF (10) has a light field coupling section (17) in which the hollow core (14) is tapered over an axial coupling section length from a fiber end core diameter (D) at the at least one fiber end (16) to the mode guiding core diameter (d). Furthermore, methods of using the HC-PCF and manufacturing the HC-PCF are described.
    Type: Grant
    Filed: May 26, 2021
    Date of Patent: May 2, 2023
    Assignee: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Sebastian Thomas Bauerschmidt, Patrick Sebastian Uebel, Philip St. J. Russell
  • Publication number: 20230087805
    Abstract: The present invention relates to inhibitors of the interaction between H. pylori HopQ and a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as well as to immunogenic compositions based on H. pylori HopQ. The present invention further relates to the use of the inhibitors and immunogenic compositions for preventing or treating a disease or disorder caused by or associated with H. pylori.
    Type: Application
    Filed: September 21, 2022
    Publication date: March 23, 2023
    Applicants: TECHNISCHE UNIVERSITÄT MÜNCHEN, MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Anahita JAVAHERI, Tobias KRUSE, Markus GERHARD, Bernhard B. SINGER, Daniel HORNBURG, Han REMAUT, Matthias MANN, Felix MEISSNER, Steffen BACKERT
  • Patent number: 11608570
    Abstract: The present invention relates to a method for producing a panel of cells (i.e. a cell library) expressing various different mutant variants of a protein of interest, wherein only one of said mutant variants is expressed per cell from a single gene copy. The present invention also relates to a method or cell library for identifying a mutant variant of a protein of interest having a different or modified biological activity as compared to the corresponding wild-type protein of interest. According to the present invention the identified mutant variant of a protein of interest may be applied for white biotechnology.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: March 21, 2023
    Assignee: Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V.
    Inventors: David Ng, Oliver Griesbeck, Mutlu Erdogan
  • Publication number: 20230073506
    Abstract: The invention relates to a workstation (1), a preparation station (2) and a method for manipulating an electron microscopy grid assembly (3). The workstation (1) comprises a first compartment (101), a first gas inlet (102) for generating an overpressure in the first compartment (101), a first glove (104) and a second glove (105), each being fixed in a respective opening (106, 107) of the workstation (1), wherein the first glove (104) and the second glove (105) are movable in the first compartment (101) to manipulate objects in the first compartment (101), wherein the workstation (1) comprises a port (109) for providing a transfer device (4) for an electron microscopy grid assembly (3) in the first compartment (101).
    Type: Application
    Filed: February 4, 2021
    Publication date: March 9, 2023
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E. V.
    Inventors: Sebastian TACKE, Stefan RAUNSER
  • Publication number: 20230067910
    Abstract: The present invention relates to compounds represented by general formula (Ia), (Ib), (IIa) or (IIb). These compounds are suitable for imaging alpha-synuclein and for diagnosing diseases which are associated with the aggregation of alpha-synuclein. The compounds are also useful for treating and preventing diseases which are associated with the aggregation of alpha-synuclein.
    Type: Application
    Filed: November 19, 2020
    Publication date: March 2, 2023
    Applicants: MODAG GMBH, MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Armin GIESE, Felix SCHMIDT, Daniel WECKBECKER, Andrei LEONOV, Sergey RYAZANOV, Christian GRIESINGER, Bernd PICHLER, Kristina HERFERT, Andreas MAURER, Laura KÜBLER, Sabrina BUSS
  • Patent number: 11595133
    Abstract: A quantum device includes a non-reciprocal transmission structure, wherein the transmission structure is designed such that for first waves traversing the transmission structure in a forward direction the phases of the first waves are at least partially conserved, and for second waves traversing the transmission structure in a backward direction, the phases of the second waves are at least partially replaced by random ones, such that the phase conservation is more pronounced in the forward direction than in the backward direction.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: February 28, 2023
    Assignee: Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V.
    Inventors: Jochen Mannhart, Daniel Braak
  • Patent number: 11573231
    Abstract: The present invention relates to a marker that can be used as aging biomarker. More specifically, the present invention relates to the analysis of nucleolar size as a biomarker for aging and metabolic health and its relation to the virtual age, or the life expectancy of animals, including humans. The aging biomarker of the invention can be used to study the effect of medication, food compounds and/or special diets on the wellness and virtual age, or the life expectancy of animals, including humans.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: February 7, 2023
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.v.
    Inventors: Adam Antebi, Varnesh Tiku, Pieternella Slagboom
  • Patent number: 11569918
    Abstract: A quantum device comprising a transmission structure, wherein based on quantum collapse, interference and selective absorption the transmission structure is designed such that quantum waves emitted by at least two bodies, for example, by thermal excitation, are passed preferentially to a subset of these bodies.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: January 31, 2023
    Assignee: Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V.
    Inventors: Jochen Mannhart, Daniel Braak
  • Publication number: 20230027067
    Abstract: An optical component comprising a planar metasurface arranged on a surface of a first substrate and a top layer arranged in a height direction Z above the metasurface, wherein the metasurface comprises a plurality of scattering structures, wherein a dielectric material is deposited on a subset of the plurality of scattering structures, wherein an active media is sandwiched between the metasurface and the top layer, wherein an incident electromagnetic radiation is transmitted or reflected by the optical component, wherein a phase profile modulation is induced on the incident electromagnetic radiation during the reflection or transmission.
    Type: Application
    Filed: November 13, 2020
    Publication date: January 26, 2023
    Applicant: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
    Inventors: Laura Na LIU, Jianxiong LI