Abstract: Low melting propionic acid derivative particles that are free flowing and have significantly reduced or eliminated throat burn are disclosed. A method of manufacturing the low melting propionic acid derivative particles; dosage forms containing the low melting propionic acid derivative particles; methods of manufacturing the dosage forms; and methods of treatment using the dosage forms are also disclosed.
Abstract: Low melting propionic acid derivative particles that are free flowing and have significantly reduced or eliminated throat burn are disclosed. A method of manufacturing the low melting propionic acid derivative particles; dosage forms containing the low melting propionic acid derivative particles; methods of manufacturing the dosage forms; and methods of treatment using the dosage forms are also disclosed.
Abstract: Systems, methods and apparatuses for manufacturing dosage forms, and to dosage forms made using such systems, methods and apparatuses are provided. Novel compression, thermal cycle molding, and thermal setting molding modules are disclosed. One or more of such modules may be linked, preferably via novel transfer device, into an overall system for making dosage forms.
Type:
Grant
Filed:
December 7, 2011
Date of Patent:
March 18, 2014
Assignee:
McNeil-PPC, Inc.
Inventors:
Harry S. Sowden, Bernard F. Plantz, Shun Por Li
Abstract: The present invention relates to a medicinal dosage form having a first core, a second core, and a shell that surrounds a first portion of each core and a fill material that covers a second portion of at least one core, wherein the fill material that is provided over at least one core is not in contact with any portion of the other core. e. The inventive dosage forms provide modified release of one or more active ingredients contained therein. The present invention also relates to methods for manufacturing such medicinal dosage forms.
Abstract: A system for organizing very similar articles in a container so that the user can readily identify the desired article. A “menu” may be used to readily identify the articles, which preferably are non-food, consumer items, such as bandages or first-aid supplies. The “menu” may be provided in the lid of the container. If desired, the “menu” may be fixedly provided in the lid of the container, such as on the interior-facing surface of a flip-top or hinged-lid of the container. The articles may be organized in an insert or tray that is removable from a shell portion of the container so the shell can be used for other purposes.
Type:
Grant
Filed:
July 27, 2007
Date of Patent:
March 18, 2014
Assignee:
McNeil-PPC, Inc.
Inventors:
Elysha Huntington, Anthony B. Gallo, David Lutness
Abstract: An oral care device suitable for use in providing a beneficial effect to an oral cavity of a mammal, which device includes means for providing reciprocation of a liquid effective for providing the beneficial effect of the oral cavity when the liquid is contacted with a plurality of surfaces thereof under conditions effective to provide the beneficial effect.
Type:
Application
Filed:
November 25, 2013
Publication date:
March 13, 2014
Applicant:
McNeil-PPC, Inc.
Inventors:
Richard J. Fougere, Robert W. Fusi II, Justin McDonough, Harold D. Ochs
Abstract: A chewing gum comprising at least one active pharmaceutical ingredient (API) with a core onto which is applied at least one inner polymer film coating and thereafter onto which is applied at least one outer hard coating. A preferred API is nicotine. Flavoring agents may be incorporated in the core, in the at least one inner polymer film coating and/or in the at least one outer hard coating. The gums formed exhibit a long lasting effect of flavoring agent(s) and result in the domination of flavoring agents in the coating(s) over flavoring agent(s) in the core, thereby (a) avoiding problems of chemical or pharmaceutical incompatibility between an API in the core and flavoring agent(s) in the coating(s) and (b) achieving an increased control of the release of the API and of non-active excipients.
Abstract: A fluid management device for use in a mammalian body has at least one fluid transport element capable of interfacing with a mammalian body element to provide a substantially uninterrupted fluid conduit. The fluid conduit provides a fluid path between at least one fluid transport element and the storage element. A distal portion of the at least one fluid transport element is capable of extending away from the fluid storage element.
Type:
Application
Filed:
October 25, 2013
Publication date:
February 20, 2014
Applicant:
McNeil-PPC, Inc.
Inventors:
David J. Chase, Erin Marsee, Tara Glasgow
Abstract: An intravaginal device has a fluid storage element having a longitudinal axis and is in fluid communication with at least one fluid transport element. The at least one fluid transport element has a first plate having an outwardly oriented surface and an inwardly oriented surface and a second plate coupled to the first plate. The second plate has a first surface disposed and maintained in facing relationship with the inwardly oriented surface of the first plate and an opposite surface. The second plate is capable of separating from the first plate sufficiently to provide inter-plate capillary action. The at least one fluid transport element is bendable about an axis substantially parallel to the longitudinal axis of the fluid storage element.
Type:
Grant
Filed:
May 14, 2004
Date of Patent:
February 18, 2014
Assignee:
McNeil-PPC, Inc.
Inventors:
David J. Chase, Erin Marsee, Mari Hou, Tara Glasgow, Julia K. Iris, Jennifer Sturgeon
Abstract: An applicator for urinary incontinence devices has an insertion barrel, a deployment plunger, and an adjustable insertion depth indicator. The applicators are useful to correct for a consumer's body mass index to ensure that urinary incontinence devices are placed in the appropriate position to be effective.
Type:
Grant
Filed:
April 9, 2010
Date of Patent:
February 18, 2014
Assignee:
McNeil-PPC, Inc.
Inventors:
Mari Hou, Raymond J. Hull, Jr., Paul B. Swick
Abstract: A tooth sensitivity treatment composition is disclosed. The composition includes a compound of formula I M1-A-M2-B-M1??(I) wherein: M1 is a monovalent or divalent metal; M2 is a polyvalent metal or metal oxide; and A and B are, independently, selected from the group consisting of C2-C6 diacids, triacids, and tetraacids. Methods for treating tooth sensitivity are also disclosed.
Abstract: Provided are compositions comprising a depilatory active; and a surfactant, wherein the composition has a Yield Stress of from about 1 Pascal (Pa) to about 1500 Pa, and methods of use thereof.
Abstract: An oral care device suitable for use in providing a beneficial effect to an oral cavity of a mammal, which device includes means for providing reciprocation of a liquid effective for providing the beneficial effect of the oral cavity when the liquid is contacted with a plurality of surfaces thereof under conditions effective to provide the beneficial effect.
Type:
Grant
Filed:
July 28, 2010
Date of Patent:
December 31, 2013
Assignee:
McNeil-PPC, Inc.
Inventors:
Richard J. Fougere, Robert W. Fusi, II, Justin McDonough, Harold D. Ochs
Abstract: An intravaginal device has a working portion (e.g., intravaginal urinary incontinence device suppository, tampon) and an anchoring portion comprising at least one member extending beyond at least one end of the working portion to maintain the working portion in place during use.
Type:
Grant
Filed:
July 10, 2006
Date of Patent:
December 24, 2013
Assignee:
McNeil-PPC, Inc.
Inventors:
Michelle Bartning, Kevin F. Gironda, Mari Hou, Thomas P. Luchino, Kirsten Freislinger Luehrs, Pramod Mavinkurve, Leonard Rosenfeld, Raymond J. Hull, Jr., David J. Chase
Abstract: An intravaginal device has a working portion (e.g., intravaginal urinary incontinence device suppository, tampon) and an anchoring portion comprising at least one member extending beyond at least one end of the working portion to maintain the working portion in place during use.
Type:
Grant
Filed:
May 10, 2010
Date of Patent:
December 17, 2013
Assignee:
McNeil-PPC, Inc.
Inventors:
Michelle Bartning, Kevin F. Gironda, Mari Hou, Thomas P. Luchino, Kirsten Freislinger Luehrs, Pramod Mavinkurve, Leonard Rosenfeld, Raymond J. Hull, Jr., David J. Chase
Abstract: The invention provides a composition containing hyaluronic acid (HA) or a pharmaceutically-acceptable salt thereof preserved with a cationic preservative and related methods. In one embodiment, the pharmaceutically-acceptable salt is sodium hyaluronate. In another embodiment, the cationic preservative includes benzalkonium chloride (BAK).
Abstract: An intravaginal device has a fluid storage element having a longitudinal axis and is in fluid communication with at least one fluid transport element. The at least one fluid transport element has a first plate having an outwardly oriented surface and an inwardly oriented surface and a second plate coupled to the first plate. The second plate has a first surface disposed and maintained in facing relationship with the inwardly oriented surface of the first plate and an opposite surface. The second plate is capable of separating from the first plate sufficiently to provide inter-plate capillary action. The at least one fluid transport element is bendable about an axis substantially parallel to the longitudinal axis of the fluid storage element.
Type:
Grant
Filed:
March 12, 2009
Date of Patent:
December 10, 2013
Assignee:
McNeil-PPC, Inc.
Inventors:
David J. Chase, Erin Marsee, Mari Hou, Tara Glasgow, Julia K. Iris, Jennifer Sturgeon
Abstract: A tooth sensitivity treatment composition is disclosed. The composition includes a compound of formula I M1-A-M2-B-M1??(I) wherein: M1 is a monovalent or divalent metal; M2 is a polyvalent metal or metal oxide; and A and B are, independently, selected from the group consisting of C2-C6 diacids, triacids, and tetraacids. Methods for treating tooth sensitivity are also disclosed.