Patents Assigned to Merck Patent Gesellschaft mit beschrankter Haftung
  • Patent number: 10273409
    Abstract: The present invention relates to liquid-crystalline media (LC media) having negative or positive dielectric anisotropy comprising self-aligning mesogens (SAMs) which effect homeotropic (vertical) alignment of the LC media at a surface or the cell walls of a liquid-crystal display (LC display). The invention therefore also encompasses LC displays having homeotropic alignment of the liquid-crystalline medium (LC medium) without conventional imide alignment layers. The LC media may be supplemented by a polymerizable or polymerized component, which serves for stabilization of the alignment, for adjustment of the tilt angle and/or as passivation layer.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: April 30, 2019
    Assignee: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Archetti Graziano, Andreas Taugerbeck
  • Patent number: 10155774
    Abstract: The invention relates to novel polymers containing repeating units based on benzodithiophene or derivatives thereof, monomers and methods for their preparation, their use as semiconductors in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices, and to OE and OPV devices comprising these polymers.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: December 18, 2018
    Assignee: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: William Mitchell, Steven Tierney, Changsheng Wang, Nicolas Blouin
  • Patent number: 9944663
    Abstract: The invention relates to a process of preparing substituted pentacenes, to novel pentacenes prepared by this process, to the use of the novel pentacenes as semiconductors or charge transport materials in optical, electrooptical or electronic devices including field effect transistors (FETs), electroluminescent, photovoltaic and sensor devices, and to FETs and other semiconducting components or materials comprising the novel pentacenes.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: April 17, 2018
    Assignee: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Steven Tierney, Martin Heeney, Clare Bailey, Weimin Zhang
  • Publication number: 20180022997
    Abstract: The present invention relates to liquid-crystalline media (LC media) having negative or positive dielectric anisotropy comprising self-aligning mesogens (SAMs) which effect homeotropic (vertical) alignment of the LC media at a surface or the cell walls of a liquid-crystal display (LC display). The invention therefore also encompasses LC displays having homeotropic alignment of the liquid-crystalline medium (LC medium) without conventional imide alignment layers. The LC media may be supplemented by a polymerisable or polymerised component, which serves for stabilisation of the alignment, for adjustment of the tilt angle and/or as passivation layer.
    Type: Application
    Filed: August 1, 2017
    Publication date: January 25, 2018
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Archetti GRAZIANO, Andreas TAUGERBECK
  • Patent number: 9868904
    Abstract: The present invention relates to liquid-crystalline media (LC media) having negative or positive dielectric anisotropy comprising self-aligning mesogens (SAMs) which effect homeotropic (vertical) alignment of the LC media at a surface or the cell walls of a liquid-crystal display (LC display). The invention therefore also encompasses LC displays having homeotropic alignment of the liquid-crystalline medium (LC medium) without conventional imide alignment layers. The LC media may be supplemented by a polymerizable or polymerized component, which serves for stabilization of the alignment, for adjustment of the tilt angle and/or as passivation layer.
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: January 16, 2018
    Assignee: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Archetti Graziano, Andreas Taugerbeck
  • Patent number: 9777216
    Abstract: The invention relates to a liquid-crystalline medium which comprises at least one compound of the formula I, and to the use thereof for an active-matrix display, in particular based on the VA, PSA, PS-VA, PALC, FFS or IPS effect.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: October 3, 2017
    Assignee: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Melanie Klasen-Memmer, Matthias Bremer, Konstantin Schneider
  • Patent number: 9745512
    Abstract: The invention relates to liquid-crystalline mixtures comprising at least one compound of the formula I, in which X, L1, L2, L3, L4 and alkenyl have the meanings indicated in claim 1, in order to increase the pretilt at the polyimide surface, and to liquid-crystalline media comprising one or more compounds of the formula I in electro-optical liquid-crystal displays and in LC lenses.
    Type: Grant
    Filed: February 15, 2011
    Date of Patent: August 29, 2017
    Assignee: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Michael Wittek, Brigitte Schuler, Volker Reiffenrath
  • Publication number: 20170166567
    Abstract: The invention relates to compounds of the formulae (I) and (II) in which R1, R2, R3, R4, R5, R8, X and m have the meaning indicated in the claims, and/or physiologically acceptable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios. The compounds of the formula (I) can be used for the inhibition of serine/threonine protein kinases and for the sensitisation of cancer cells to anticancer agents and/or ionising radiation. The invention also relates to the use of the compounds of the formula (I) in the prophylaxis, therapy or progress control of cancer, tumours, metastases or angiogenesis disorders, in combination with radiotherapy and/or an anticancer agent. The invention furthermore relates to a process for the preparation of the compounds of the formula (I).
    Type: Application
    Filed: February 27, 2017
    Publication date: June 15, 2017
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Thomas FUCHSS, Werner MEDERSKI, Frank ZENKE
  • Patent number: 9598408
    Abstract: The invention relates to compounds of the formulae (I) and (II) in which R1, R2, R3, R4, R5, R8, X and m have the meaning indicated in the claims, and/or physiologically acceptable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios. The compounds of the formula (I) can be used for the inhibition of serine/threonine protein kinases and for the sensitisation of cancer cells to anticancer agents and/or ionising radiation. The invention also relates to the use of the compounds of the formula (I) in the prophylaxis, therapy or progress control of cancer, tumours, metastases or angiogenesis disorders, in combination with radiotherapy and/or an anticancer agent. The invention furthermore relates to a process for the preparation of the compounds of the formula (I).
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: March 21, 2017
    Assignee: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Thomas Fuchss, Werner Mederski, Frank Zenke
  • Publication number: 20170066966
    Abstract: The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (??), which is distinguished by the fact that it has a value for the ratio ?1/?n2 in the range 6-45 with a clearing point of >60° C. and a ?? of ??2.3. Media of this type are particularly suitable for electro-optical displays having active-matrix addressing based on the ECB, PA LCD, FFS or IPS effect.
    Type: Application
    Filed: August 16, 2013
    Publication date: March 9, 2017
    Applicant: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Melanie KLASSEN-MEMMER, Sabine SCHOEN
  • Patent number: 9455059
    Abstract: The invention relates to novel phenanthro[1,10,9,8-c,d,e,f,g]carbazole polymers, methods and materials for their preparation, their use as semiconductors in organic electronic (OE) devices, and to OE devices comprising these polymers.
    Type: Grant
    Filed: July 14, 2010
    Date of Patent: September 27, 2016
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Nicolas Blouin, William Mitchell, Changsheng Wang, Steven Tierney
  • Publication number: 20160152546
    Abstract: The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays having a polymer-stabilised blue phase, and in LC media for LC displays of the PS or PSA type (“polymer sustained” or “polymer sustained alignment”), and to LC media and LC displays comprising these compounds.
    Type: Application
    Filed: February 5, 2016
    Publication date: June 2, 2016
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Axel JANSEN, Thorsten KODEK, Helmut HAENSEL, Erdal DURMAZ
  • Publication number: 20160046866
    Abstract: The present invention relates to a device for high-frequency technology, or for the microwave region and millimetre wave region of the electromagnetic spectrum, characterised in that it contains a liquid-crystal medium which consists of one or more compounds, which one or more compounds, which contain 6 to 15 five-, six- or seven-membered rings, preferably 1,4-linked phenylene rings, or in that it contains a liquid-crystal medium which itself comprises a component A, which itself consists of one or more of the said compounds, which one or more compounds, which contain 6 to 15 five-, six- or seven-membered rings, preferably 1,4-linked phenylene rings. The present invention additionally relates to compounds of the formula (I), in which the parameters have the meanings given in the text, and to the corresponding, novel liquid-crystal media, to the use and preparation thereof, and to the production and use of the devices.
    Type: Application
    Filed: October 23, 2015
    Publication date: February 18, 2016
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Atsutaka MANABE, Christian JASPER, Volker REIFFENRATH, Elvira MONTENEGRO, Detlef PAULUTH
  • Patent number: 9212244
    Abstract: The present invention relates to curable mixtures for the sealing, encapsulation, bonding or coating of opto-electronic components, such as OLEDs, solar cells, optical sensors and liquid-crystal displays, or for the alignment of liquid crystals. The mixtures comprise in total at least 50 percent by weight of vinyl ethers.
    Type: Grant
    Filed: February 25, 2010
    Date of Patent: December 15, 2015
    Assignee: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Matthias Koehler, Volker Meyer, Edgar Boehm, Michael Junge, Eike Poetsch
  • Publication number: 20150353575
    Abstract: The invention relates to novel polymers containing repeating units based on benzodithiophene or derivatives thereof, monomers and methods for their preparation, their use as semiconductors in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices, and to OE and OPV devices comprising these polymers.
    Type: Application
    Filed: August 19, 2015
    Publication date: December 10, 2015
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: William MITCHELL, Steven TIERNEY, Changsheng WANG, Nicolas BLOUIN
  • Publication number: 20150203491
    Abstract: The invention relates to compounds of the formulae (I) and (II) in which R1, R2, R3, R4, R5, R8, X and m have the meaning indicated in the claims, and/or physiologically acceptable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios. The compounds of the formula (I) can be used for the inhibition of serine/threonine protein kinases and for the sensitisation of cancer cells to anticancer agents and/or ionising radiation. The invention also relates to the use of the compounds of the formula (I) in the prophylaxis, therapy or progress control of cancer, tumours, metastases or angiogenesis disorders, in combination with radiotherapy and/or an anticancer agent. The invention furthermore relates to a process for the preparation of the compounds of the formula (I).
    Type: Application
    Filed: April 1, 2015
    Publication date: July 23, 2015
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Thomas FUCHSS, Werner MEDERSKI, Frank ZENKE
  • Publication number: 20150197819
    Abstract: The invention relates to biomarkers based on gene expression products and methods for determining the efficacy of anti-EGFR antibodies in the treatment of EGFR expressing cancer. The invention is further related to the prediction of sensitivity or resistance of a patient suffering from EGFR expressing cancer to the treatment of said patient with a specific anti-EGFR antibody. The invention is preferably related to the identification of respective biomarkers that allow a better prediction of the clinical outcome of the treatment with anti-EGFR antibodies in patients with KRAS wild-type tumors. In this context, the invention especially relates to anti-EFGR antibody c225/cetuximab (Erbitux®) and its use in patients suffering from colorectal Cancer (CRC).
    Type: Application
    Filed: March 25, 2015
    Publication date: July 16, 2015
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Christopher STROH, Anja VON HEYDEBRECK
  • Publication number: 20150166588
    Abstract: The invention relates to a process for the preparation of salts having perfluoroalkyltricyano- or perfluoroalkylcyanofluoroborate anions, ((per)fluoro)phenyltricyano- or ((per)fluoro)phenylcyanofluoroborate anions, phenyltricyanoborate anions which are mono- or disubstituted by perfluoroalkyl groups having 1 to 4 C atoms or phenylcyanofluoroborate anions which are mono- or disubstituted by perfluoroalkyl groups having 1 to 4 C atoms, by reaction of alkali metal trifluoroperfluoroalkylborate with trialkylsilyl cyanide and a subsequent salt-exchange reaction or by direct reaction of an organic trifluoroperfluoroalkyl borate with trialkylsilyl cyanide.
    Type: Application
    Filed: November 18, 2014
    Publication date: June 18, 2015
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Nikolai (Mykola) IGNATYEV, Michael SCHULTE, Jan SPRENGER, Maik FINZE, Walter FRANK
  • Publication number: 20150140024
    Abstract: The present invention relates to the preparation and use of recombinant variants of group 5 allergens of the Poaceae (true grasses), which are characterised by reduced IgE reactivity compared with known wild-type allergens and at the same time substantially retained reactivity with T-lymphocytes.
    Type: Application
    Filed: December 17, 2010
    Publication date: May 21, 2015
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Martin Wald, Andreas Nandy, Helmut Fiebig, Bernhard Weber, Helga Kahlert, Gerald Reese, Oliver Cromwell
  • Patent number: 8802813
    Abstract: The invention relates to novel polymers comprising cyclohexylene groups which are especially suitable for use in birefringent films with negative optical dispersion, to novel formulations and polymer films comprising them, and to the use of the polymers, formulations and films in optical, electrooptical, electronic, semiconducting or luminescent components or devices.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: August 12, 2014
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Kevin Adlem, Owain Llyr Parri, David Wilkes, Claire Topping