Abstract: A pharmaceutical composition for promoting the proliferation of human corl endothelium comprising:1 ml of 0.15M phosphate buffer, at pH 7.4;400-800 .mu.g of heparin;1.0-5.0 .mu.g of Cu.sup.2+ ;37.5-375 .mu.g of /3-0-b-D-gelactopyranosyl-(1-4)-0-(2-acetamido-b-D-glucopyranosyl-6-sulfat e)-1/as the salt of a basic metal; and12.5-125 .mu.g of copolymer (b-gucuronic acid (1-3)-N-acetyl-b-galactosamino-4-(or 6-) -sulfate-(1-4) as the salt of a basic metal. Such a composition is particularly useful for promoting the proliferation of human corneal endothelium in conditions associated with cataract extraction followed by artificial lens implantation, wherein the composition is injected into the patient's anterior eye chamber in an amount of between 0.2-02.25 ml, immediately after performing the operation. In all other cases, the pharmaceutical composition is injected into a patient's anterior eye chamber by phonophoresis in a continuous mode, at intensity 0.1-0.3 V/cm.sup.
Type:
Grant
Filed:
November 1, 1996
Date of Patent:
December 8, 1998
Assignee:
Mezhotraslevoi Nauchno-Tekhnichesky Komplex "Mikrokhirurgia Glaza"
Inventors:
Svyatoslav Nikolaevich Fedorov, Tamara Iliinichna Ronkina, Andrei Valentinovich Zolotarevsky, Sergei Nikolaevich Bagrov, Sergei Viktorovich Novikov, Evgeny Viktorovich Larionov
Abstract: The polymer material is a mixture, consisting substantially of:oligourethanemethacrylate having the following structural formula: ##STR1## methylcarbitol methacrylate ##STR2## methacrylic acid ##STR3## and 2,2'-dimethoxy-2-phenylacetophenone ##STR4## taken in ratio that ensure the ability of the mixture to light curing under the effect of UV radiation. The intraocular lens comprises an optic and a supporting portion, both made substantially of the mentioned polymer material.
Type:
Grant
Filed:
May 31, 1996
Date of Patent:
March 10, 1998
Assignees:
Mezhotraslevoi Nauchno-Tekhnichesky Komplex "Mikrokhirurgia Glaza", Tovarischestvo S Ogranichennoi Otvetstvennostju "Svetoplastik"
Inventors:
Svyatoslav Nikolaevich Fedorov, Leonid Feodosicvich Linnik, Valery Mikhailovich Treushnikov, Elena Alexandrovna Viktorova
Abstract: An intraocular lens includes a optical body including a posterior concave rface with a first radius of curvature, a periphery and a central, axially aligned opening that enhances liquid circulation in the eye, with the ratio of the height of the optical body to the overall height of the lens being between about 0.25 to about 0.5; a positioning element connected to the optical body periphery and including a periphery and a posterior concave surface with a second radius of curvature greater than the first radius of curvature, a ratio of the first to second radii of curvature being between about 0.31 to about 0.
Type:
Grant
Filed:
April 22, 1994
Date of Patent:
January 2, 1996
Assignee:
Mezhotraslevoi Nauchno-Tekhnichesky Komplex "Mikrokhirurgia Glaza"
Abstract: A method for treatment of diseases of the optic tract resides in a rotating magnetic field, which rotates at a variable angular velocity and its rotation is brought in synchronism with the blood flow pulsation in the internal carotid artery, is applied to the bridge of the nose, to the upper portion of the orbit of both eyes, to the temporal areas, to both of the auriculo-temporal regions, and to the region of a projection of the visual analyzers.A device for treatment of diseases of the optic tract, comprising a housing, accommodating a drive and a main permanent magnet whose axle is connected to the shaft of a drive through an elastic element. Besides, a magnetic brake is accommodated in the housing in the zone of action of the magnetic field.
Type:
Grant
Filed:
June 11, 1991
Date of Patent:
February 4, 1992
Assignee:
Mezhotraslevoi Nauchno-Tekhnichesky Komplex "Mikrokhirurgia Glaza"
Inventors:
Svyatoslav N. Fedorov, Leonid F. Linnik, Gennady M. Antropov, Leonid N. Arnautov, Vladimir V. Ippolitov, Valentin F. Streltsov, Alexandr P. Stromakov, Nina A. Shigina
Abstract: A device for ophthalmologic operations comprised of a holder (1), a cutting nstrument (9) provided with a catch (10) and secured on a spring-loaded rod (7) accommodated inside of the holder (1) and having a micrometric thread (11) on the other end. Mounted on the holder (1) by means of a micrometric thread (15) is a thrust bushing (14) which carries the catch which fixes the position of this bushing (14) and is interconnected with a nut by which the rod (2) is moved.
Type:
Grant
Filed:
November 23, 1987
Date of Patent:
December 5, 1989
Assignee:
Mezhotraslevoi Nauchno-tekhnichesky Komplex "Mikrokhirurgia Glaza"
Inventors:
Svyatoslav N. Fedorov, Sergei A. Soloviev, Evgeny I. Degtev, Albina I. Ivashina, Alexandr A. Karavaev